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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Genital Prolapse Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

Does Spinal Anesthesia for Prolapse Surgery With Lead to Urinary Retention?

NCT02547155
View directory record Official record
Conditions
Urinary Retention, Uterine Prolapse
Interventions
Spinal anesthesia, General anesthesia
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
40 Years and older · Female only
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Weston, Florida
Source: ClinicalTrials.gov public record
Updated Apr 19, 2017 · Synced Sep 24, 2026, 7:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Laparoscopic Versus Robotic Assisted Laparoscopic Sacrocolpopexy for Vaginal Prolapse

NCT00551993
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
robotic laparoscopic sacrocolpopexy, Laparoscopic Sacral Colpopexy
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
21 Years and older · Female only
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2011
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 18, 2014 · Synced Sep 24, 2026, 7:03 PM EDT
Completed Phase 4 Interventional Results available

Investigation to Minimize Prolapse Recurrence of the Vagina Using Estrogen

NCT02431897
View directory record Official record
Conditions
Pelvic Organ Prolapse, Urogenital Prolapse, Vaginal Vault Prolapse, Cystocele, Uterine Prolapse, Vaginal Prolapse, Pelvic Floor Disorders
Interventions
Conjugated Estrogens Cream, Placebo Cream
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
48 Years and older · Female only
Enrollment
206 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
3
States / cities
Birmingham, Alabama • Providence, Rhode Island • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 5, 2023 · Synced Sep 24, 2026, 7:03 PM EDT
Completed Not applicable Interventional

Evaluating Sexual Function After Vaginal Repair With Perineorrhaphy

NCT01779739
View directory record Official record
Conditions
Sexual Function
Interventions
Perineorrhaphy
Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
19 Years to 105 Years · Female only
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
2
States / cities
Birmingham, Alabama • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 21, 2018 · Synced Sep 24, 2026, 7:03 PM EDT
Completed No phase listed Observational Results available

Restorelle Direct Fix Anterior and Posterior (A&P) for Female Pelvic Organ Prolapse: A Prospective Post Market Study

NCT01378065
View directory record Official record
Conditions
Pelvic Organ Prolapse (POP)
Interventions
Restorelle Direct Fix A&P
Device
Lead sponsor
Coloplast A/S
Industry
Eligibility
18 Years and older · Female only
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
6
States / cities
Baltimore, Maryland • Grand Rapids, Michigan • Marshall, Missouri + 3 more
Source: ClinicalTrials.gov public record
Updated May 11, 2020 · Synced Sep 24, 2026, 7:03 PM EDT
Active, not recruiting Not applicable Interventional

Impact of Preop Video on Patient Anxiety

NCT05633901
View directory record Official record
Conditions
Prolapse, Vaginal, Prolapse, Uterine, Prolapse; Female
Interventions
Educational Video, Standard Counseling
Other
Lead sponsor
TriHealth Inc.
Other
Eligibility
18 Years and older · Female only
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
2
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 21, 2024 · Synced Sep 24, 2026, 7:03 PM EDT
Active, not recruiting Not applicable Interventional

Clinical Investigation of the da Vinci Surgical System

NCT05682742
View directory record Official record
Conditions
Thymoma, Mediastinal Tumor, Gynecologic Disease, Gynecologic Cancer, Pelvic Organ Prolapse, Prostate Disease, Prostate Cancer, Inguinal Hernia, Ventral Hernia, Obesity, Morbid
Interventions
Robotic-assisted Surgery
Device
Lead sponsor
Intuitive Surgical
Industry
Eligibility
21 Years and older
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
4
States / cities
Orlando, Florida • Lansing, Michigan • Ridgewood, New Jersey + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 2, 2024 · Synced Sep 24, 2026, 7:03 PM EDT
Not listed No phase listed Observational

A RETROspective Data Collection of comPRESSion Anastomosis Using the ColonRing

NCT01880918
View directory record Official record
Conditions
Diverticulum, Colon, Colorectal Neoplasms, Crohn Disease, Colitis, Ulcerative, Colostomy, Ileostomy - Stoma, Rectal Prolapse, Intestinal Polyposis, Lymphoma, Endometriosis, Intestinal Volvulus
Interventions
Not listed
Lead sponsor
novoGI
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
3
States / cities
Atlamonte Springs, Florida • Port Charlotte, Florida • Springfield, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 18, 2013 · Synced Sep 24, 2026, 7:03 PM EDT
Completed Not applicable Interventional Results available

Prediction of Postsurgical Symptomatic Outcomes With Preoperative Pessary Use

NCT02680145
View directory record Official record
Conditions
Vaginal Vault Prolapse, Pelvic Organ Prolapse, Uterine Prolapse, Pelvic Floor Prolapse
Interventions
Preoperative Pessary Use
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 19, 2020 · Synced Sep 24, 2026, 7:03 PM EDT
Completed Not applicable Interventional

Sacrocolpopexy With Posterior Repair Obstructed Defecation Symptoms

NCT03658395
View directory record Official record
Conditions
Vaginal Prolapse
Interventions
Laparoscopic Sacrocolopopexy, Posterior repair
Procedure
Lead sponsor
University of Oklahoma
Other
Eligibility
21 Years to 80 Years · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Dec 5, 2024 · Synced Sep 24, 2026, 7:03 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Study of Robotic Assisted Laparoscopic Sacral Colpopexy Using Alyte Mesh

NCT01320644
View directory record Official record
Conditions
Pelvic Organ Prolapse, Urinary Incontinence, Mesh Erosion
Interventions
Not listed
Lead sponsor
Atlantic Health System
Other
Eligibility
21 Years and older · Female only
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Morristown, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 10, 2016 · Synced Sep 24, 2026, 7:03 PM EDT
Completed Phase 2 Interventional Results available

Dexamethasone Administration To Improve Patient Recovery In Ambulatory Vaginal Prolapse Surgery: Is There A Role?

NCT03338400
View directory record Official record
Conditions
Quality of Recovery, Same Day Surgery, Nausea and Vomiting, Postoperative, Vaginal Prolapse
Interventions
Dexamethasone, Normal saline
Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Weston, Florida
Source: ClinicalTrials.gov public record
Updated Apr 13, 2021 · Synced Sep 24, 2026, 7:03 PM EDT
Terminated No phase listed Observational

Exair® Versus Native Tissue Repair for Prolapse

NCT02162628
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Exair Prolapse Repair System, Total Native Tissue Repair
Device · Procedure
Lead sponsor
Coloplast A/S
Industry
Eligibility
18 Years and older · Female only
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
13
States / cities
Savannah, Georgia • Fort Wayne, Indiana • Dearborn, Michigan + 9 more
Source: ClinicalTrials.gov public record
Updated Dec 13, 2015 · Synced Sep 24, 2026, 7:03 PM EDT
Completed Phase 4 Interventional Results available

Lessons on Urethral Lidocaine in Urodynamics

NCT04038099
View directory record Official record
Conditions
Urethra Issue, Pelvic Organ Prolapse, Urinary Incontinence, Vaginal Vault Prolapse, Cystocele, Uterine Prolapse, Vaginal Prolapse, Pelvic Floor Disorders
Interventions
Water-Based Vaginal Lubricant, lidocaine topical
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 31, 2023 · Synced Sep 24, 2026, 7:03 PM EDT
Completed No phase listed Observational

What is the Impact of the Presence of a Support Person on Informed Consent

NCT03966469
View directory record Official record
Conditions
Surgery, Knowledge, Attitudes, Practice, Prolapse, Vaginal, Urinary Incontinence
Interventions
Preoperative support person present, Patient Present Only
Other
Lead sponsor
Hartford Hospital
Other
Eligibility
18 Years to 89 Years · Female only
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 6, 2020 · Synced Sep 24, 2026, 7:03 PM EDT
Active, not recruiting Not applicable Interventional

Patient-Centered Outcomes in the Surgical Treatment of Uterovaginal Prolapse

NCT05063331
View directory record Official record
Conditions
Uterine Prolapse
Interventions
Minimally invasive supracervical hysterectomy and sacrocolpopexy (MI-SCH+SCP), Vaginal hysterectomy with uterosacral ligament suspension (TVH+USLS)
Procedure
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2029
U.S. locations
7
States / cities
Jacksonville, Florida • Chicago, Illinois • Durham, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Sep 24, 2026, 7:03 PM EDT
Terminated No phase listed Observational

Observing Pelvic Organ Prolapse Symptoms And Treatment Outcomes

NCT00784602
View directory record Official record
Conditions
Genital Prolapse
Interventions
Not listed
Lead sponsor
Melissa Fischer, MD
Other
Eligibility
21 Years and older · Female only
Enrollment
301 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 2, 2018 · Synced Sep 24, 2026, 7:03 PM EDT
Completed No phase listed Observational

One Year Outcome After Robotic Assisted Laparoscopic Sacral Colpopexy, a Case Series Review

NCT01055860
View directory record Official record
Conditions
Pelvic Organ Prolapse, Urinary Incontinence
Interventions
Not listed
Lead sponsor
Atlantic Health System
Other
Eligibility
21 Years and older · Female only
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Morristown, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 21, 2011 · Synced Sep 24, 2026, 7:03 PM EDT
Completed No phase listed Observational

Electronic Catheter Stethoscope

NCT01463462
View directory record Official record
Conditions
Pelvic Organ Prolapse, Gynecologic Cancers, Uterine Leiomyomata, Adenomyosis, Endometrial Hyperplasia, Other Abnormal Uterine and Vaginal Bleeding, Pelvic Mass, Pelvic Pain
Interventions
Not listed
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older · Female only
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated May 26, 2016 · Synced Sep 24, 2026, 7:03 PM EDT
Completed Phase 4 Interventional

Dilators for Dyspareunia Prevention

NCT01299363
View directory record Official record
Conditions
Post-operative Dyspareunia
Interventions
Dilator use
Behavioral
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Apr 8, 2015 · Synced Sep 24, 2026, 7:03 PM EDT
Withdrawn Phase 2 Interventional Accepts healthy volunteers

Vaginal Creams to Reduce Vaginal Erosion in Pessary Users

NCT02316249
View directory record Official record
Conditions
Atrophy of Vagina, Vaginal Ulceration, Vaginitis
Interventions
Estradiol, placebo
Drug · Other
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
Great Neck, New York
Source: ClinicalTrials.gov public record
Updated Oct 1, 2015 · Synced Sep 24, 2026, 7:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Randomized Controlled Trial Comparing Acellular Collagen Biomesh (Pelvisoft) to Polypropylene Mesh(Pelvitex) for Sacral Colpopexy

NCT00564083
View directory record Official record
Conditions
Uterine Prolapse
Interventions
sacral colpopexy
Procedure
Lead sponsor
Atlantic Health System
Other
Eligibility
18 Years and older · Female only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2010
U.S. locations
1
States / cities
Morristown, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 21, 2011 · Synced Sep 24, 2026, 7:03 PM EDT
Completed Phase 4 Interventional Results available

Efficacy Study of Vaginal Mesh for Anterior Prolapse

NCT00557882
View directory record Official record
Conditions
Vaginal Prolapse, Uterine Prolapse, Cystocele, Pelvic Organ Prolapse
Interventions
synthetic polypropylene mesh
Device
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
21 Years and older · Female only
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Oct 29, 2020 · Synced Sep 24, 2026, 7:03 PM EDT
Active, not recruiting Not applicable Interventional

Perineal Massage for Pessary Examinations

NCT06416982
View directory record Official record
Conditions
Prolapse, Vaginal, Stress Urinary Incontinence, Pessaries, Pain
Interventions
Perineal massage
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older · Female only
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Sep 24, 2026, 7:03 PM EDT