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ClinicalTrials.gov public records Last synced Nov 15, 2026, 1:35 PM EST

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Showing 73–96 of 253 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Gingival Diseases Clear all

Conditions: Gingiviits
Interventions: oscillating-rotating powered toothbrush, side-to-side powered toothbrush; Device
Lead sponsor: Philips Clinical & Medical Affairs Global; Industry
Eligibility: 18 Years to 59 Years
Enrollment: 295 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021
U.S. locations: 1
States / cities: Fort Wayne, Indiana

Conditions: Periodontal Diseases
Interventions: Connective Tissue Graft Technique, Pinhole Surgical Technique; Procedure
Lead sponsor: State University of New York at Buffalo; Other
Eligibility: 19 Years and older
Enrollment: 43 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2023
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Gingival Recession Localized Moderate, Dental Implant
Interventions: Zderm; Device
Lead sponsor: The University of Texas Health Science Center at San Antonio; Other
Eligibility: 18 Years to 89 Years
Enrollment: 68 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Gingivitis
Interventions: 0.454% stannous fluoride, 0.76% sodium monofluorophosphate, 0.454% stannous fluoride AM and 0.76% sodium monofluorophosphate PM; Drug
Lead sponsor: Procter and Gamble; Industry
Eligibility: 18 Years and older
Enrollment: 90 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Las Vegas, Nevada

Conditions: Gingivitis
Interventions: Stent-Induced Biofilm Overgrowth; Procedure
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 30 Years
Enrollment: 6 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Post-operative Ileus
Interventions: Nicotine gum, Regular chewing gum; Drug · Other
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years to 85 Years
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: Weston, Florida

Conditions: Gingivitis
Interventions: Toothpaste without triclosan, Triclosan; Other
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years to 40 Years
Enrollment: 32 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Gingival Recession
Interventions: Tunneled coronally advanced flap; Procedure
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Idiopathic Thrombocytopenic Purpura
Interventions: Eltrombopag, Placebo; Drug
Lead sponsor: GlaxoSmithKline; Industry
Eligibility: 1 Year to 17 Years
Enrollment: 92 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 4
States / cities: Los Angeles, California • St. Petersburg, Florida • Brooklyn, New York + 1 more

Conditions: Periodontal Diseases, Gingivitis, Periodontitis, Halitosis
Interventions: Gingival health formulation in an accelerating device, Gingival health formulation on a toothbrush, OTC fluoride toothpaste; Other
Lead sponsor: Glo Science, Inc.; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 39 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Cambridge, Massachusetts

Conditions: Gingivitis, Dental Plaque
Interventions: Oscillating-rotating electric toothbrush, Sonic electric toothbrush, Manual toothbrush; Device
Lead sponsor: Procter and Gamble; Industry
Eligibility: 18 Years and older
Enrollment: 2,929 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Toothbrushing, Gingivitis, Cleft Lip and Palate
Interventions: Toothbrush; Device
Lead sponsor: Children's Hospital Los Angeles; Other
Eligibility: 6 Years to 20 Years
Enrollment: 198 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Gingival Recession
Interventions: Gintuit, Autologous palatal tissue; Device · Other
Lead sponsor: Organogenesis; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 96 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2008
U.S. locations: 4
States / cities: Boston, Massachusetts • Ann Arbor, Michigan • Houston, Texas + 1 more

Conditions: Gingivitis, Dental Plaque
Interventions: Next Science OTC Oral Rinse with Essential Oils, OTC Oral Rinse Control; Combination Product
Lead sponsor: University of Florida; Other
Eligibility: 18 Years to 60 Years
Enrollment: 118 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 2
States / cities: Gainesville, Florida

Conditions: Plaque, Gingivitis
Interventions: stannous fluoride toothpaste, cavity protection toothpaste; Drug
Lead sponsor: Procter and Gamble; Industry
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015
U.S. locations: 1
States / cities: Fort Wayne, Indiana

Conditions: Gingivitis, Investigation of Biological Markers of Inflammation
Interventions: Iocide Oral Rinse, Placebo; Drug
Lead sponsor: Biomedical Development Corporation; Industry
Eligibility: 18 Years and older
Enrollment: 76 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Gingivitis, Plaque
Interventions: Water Flosser, Control; Device · Other
Lead sponsor: Procter and Gamble; Industry
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021
U.S. locations: 1
States / cities: Fort Wayne, Indiana

Conditions: Dental Plaque, Gingivitis
Interventions: Triclosan/fluoride toothpaste, stannous fluoride toothpaste, fluoride toothpaste, Fluoride Mouthwash, cetylpyridinium chloride Mouthwash; Drug
Lead sponsor: Colgate Palmolive; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 129 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014
U.S. locations: 1
States / cities: Loma Linda, California

Conditions: Pain, Postoperative, Gingival Diseases
Interventions: amnion-chorion membrane, Sutures; Device · Procedure
Lead sponsor: Harvard Medical School (HMS and HSDM); Other
Eligibility: 18 Years to 85 Years
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Pregnancy-associated Gingivitis
Interventions: counseling; Behavioral
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 16 Years and older · Female only
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2009
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Gingival Recession
Interventions: Tunnel + AlloDerm, Tunnel + Novomatrix; Procedure
Lead sponsor: University of Louisville; Other
Eligibility: 18 Years to 120 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Louisville, Kentucky

Conditions: Oral Health Related Quality of Life (OHRQoL)
Interventions: Botanical A, Botanical B, Vehicle (Placebo solution); Dietary Supplement
Lead sponsor: Access Business Group; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Grand Rapids, Michigan

Conditions: Gingivitis, Plaque
Interventions: Oscillating-rotating electric toothbrush, Side-to-side electric toothbrush, Manual toothbrush; Device
Lead sponsor: Procter and Gamble; Industry
Eligibility: 18 Years and older
Enrollment: 2,145 participants
Timeline: 2018
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Palatal Neoplasms, Lip Neoplasm, Gingival Neoplasms, Leukoplakia, Oral, Tongue Neoplasms, Oropharyngeal Neoplasms, Oral Ulcer
Interventions: OncAlert; Device
Lead sponsor: Vigilant Biosciences, Inc.; Industry
Eligibility: 23 Years and older
Enrollment: 893 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 26
States / cities: Beverly Hills, California • La Mesa, California • Loma Linda, California + 22 more

Search by objective public record fields.

Comparion of Effects of Two Different Power Toothbrushes on Plaque and Gum Health

Pinhole Surgical Technique Compared to Connective Tissue Graft in Treatment of Gingival Recession

Free Soft Tissue Grafts (FSTG) Using Autograft Palatal Donor Tissue vs. Xenograft Collagen Matrix (Zderm™)

A Three Month Bleeding-Model Clinical Study

Atlas of Experimental Gingivitis in Humans

Nicotine Gum Recovery After Colorectal Surgery

Study of the Anti-Inflammatory Effects of Colgate Total® During an Experimental Gingivitis Model

Treatment of Gingival Recession Defects Using Platelet-Rich Fibrin With an Allogenic Dermal Matrix

Study of a New Medication for Childhood Chronic Immune Thrombocytopenia (ITP), a Blood Disorder of Low Platelet Counts That Can Lead to Bruising Easily, Bleeding Gums, and/or Bleeding Inside the Body.

Randomized Trial of a Gum Health Formulation

A Meta-analysis Comparing Toothbrushes on Plaque Removal and Gingival Health

Effectiveness of Dual Light Electric Toothbrush vs. Manual Toothbrush in Orthodontic Patients Undergoing Oral Surgery

Safety and Efficacy of Gintuit(TM)for Oral Soft Tissue Regeneration

Next Science Antimicrobial Mouth Rinse Study

A Pilot Study to Evaluate a Method for Plaque When Comparing Stannous Fluoride Toothpaste to a Regular Dentifrice

Efficacy of Iocide Oral Rinse Against Gingival Inflammation

Measuring Efficacy of an Oral-Irrigator After Three Weeks of Use

The Clinical Investigation of Toothpaste as Compared to Toothpaste and Mouthwash in Reducing Plaque and Gingivitis: A Six-week Clinical Study in the US

Effect of Using Placental Membranes on Healing and Post-op Pain After Gum Surgery

A Study to Evaluate Associations Between Gingivitis and Pregnancy Outcomes

Root Coverage Comparing an Allograft to a Bovine Xenograft

New Functional Ingredient for Oral Care

The Effects of Oscillating-Rotating Electric Toothbrushes on Plaque and Gingival Health

Clinical Evaluation of the OncAlert RAPID in Subjects Presenting for Evaluation and/or Initial Biopsy; Impact on Decision-Making