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ClinicalTrials.gov public records Last synced Nov 15, 2026, 2:14 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 121–144 of 253 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Gingival Diseases Clear all

Conditions: Gingivitis, Plaque
Interventions: manual Tooth Brush + Colgate Total TP (0.454% SnF, 1100 ppm F), manual toothbrush + Colgate dental cream; Drug
Lead sponsor: Colgate Palmolive; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 82 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024
U.S. locations: 1
States / cities: Costa Mesa, California

Conditions: Gingivitis
Interventions: Airflosser, Manual Floss; Device
Lead sponsor: Tufts University; Other
Eligibility: 18 Years to 70 Years
Enrollment: 257 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Gingivitis
Interventions: Interdental cleaning device with water, Interdental cleaning device with essential-oil mouthrinse; Device
Lead sponsor: Johnson & Johnson Consumer and Personal Products Worldwide; Industry
Eligibility: 18 Years and older
Enrollment: 140 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011
U.S. locations: 1
States / cities: Las Vegas, Nevada

Conditions: Gingival Recession
Interventions: Coronally Advanced Flap, Intrasulcular Tunneling, Vestibular Incision Subperiosteal Tunnel Access (VISTA), Leukocyte-Platelet Rich Fibrin (L-PRF); Procedure · Biological · Device
Lead sponsor: University of Southern California; Other
Eligibility: 18 Years to 70 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Gingival Diseases
Interventions: Fluoride, Triclosan and fluoride, Herbal Ingredient and fluoride; Drug
Lead sponsor: Colgate Palmolive; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 103 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Recession, Gingival
Interventions: Flap Surgery for root coverage with Alloderm and xenograft, Tunnel Surgery for root coverage with Alloderm and xenograft; Procedure
Lead sponsor: University of Louisville; Other
Eligibility: 18 Years and older
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Louisville, Kentucky

Conditions: Gingival Diseases
Interventions: 0.76% Sodium Monofluorophosphate Dentifrice, 0.454% Stannous Fluoride Dentifrice; Drug
Lead sponsor: Procter and Gamble; Industry
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022
U.S. locations: 1
States / cities: Las Vegas, Nevada

Conditions: Gingivitis
Interventions: AirFloss + BreathRx, AirFloss + Listerine, Dental Floss, Manual Toothbrush; Device
Lead sponsor: Philips Oral Healthcare; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 290 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014
U.S. locations: 1
States / cities: Las Vegas, Nevada

Conditions: Gingivitis, Supragingival Plaque
Interventions: Brushing and Flossing of teeth, Brushing Only; Device · Other
Lead sponsor: Indiana University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 64 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Gingivitis
Interventions: Oscillating rotating power toothbrush; Device
Lead sponsor: Marquette University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 55 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Milwaukee, Wisconsin

Conditions: Gingivitis
Interventions: Stannous Fluoride Dentifrice, Sodium Fluoride Dentifrice, electric toothbrush, Cetylpyridinium Chloride (CPC), manual toothbrush; Drug · Device
Lead sponsor: Procter and Gamble; Industry
Eligibility: 18 Years and older
Enrollment: 69 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011
U.S. locations: 1
States / cities: Las Vegas, Nevada

Conditions: Gingivitis
Interventions: Stannous fluoride toothpaste, Sodium fluoride toothpaste; Drug
Lead sponsor: HALEON; Industry
Eligibility: 18 Years and older
Enrollment: 159 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Fort Wayne, Indiana

Conditions: Dental Plaque
Interventions: Experimental: U-shaped Power Toothbrush, Placebo Comparator: Soft Manual Toothbrush; Device
Lead sponsor: Lander Enterprises, LLC; Industry
Eligibility: 5 Years to 8 Years
Enrollment: 22 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023
U.S. locations: 1
States / cities: Fort Wayne, Indiana

Conditions: Dental Plaque
Interventions: Automated mouthpiece-based toothbrush, Manual toothbrush; Device
Lead sponsor: University of Washington; Other
Eligibility: 5 Years to 17 Years
Enrollment: 42 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Peri-implant Mucositis, Gingivitis
Interventions: interruption of oral hygiene; Behavioral
Lead sponsor: UConn Health; Other
Eligibility: 21 Years and older
Enrollment: 18 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: Farmington, Connecticut

Conditions: Periodontitis, Gingivitis, Periodontal Disease, Periodontal Infections, Oral Infections, Periapical Infections, Pneumonia, Diabetes
Interventions: Comprehensive Oral Evaluation, Intraoral Complete Radiographic Series, • Teledentistry-synchronous and asynchronous, Periodontal Therapy, Periodontal Maintenance Procedure, Application of Caries Arresting Medicament, Oral Hygiene Assistance, Referral for Treatment of Acute Oral Infection; Other · Procedure
Lead sponsor: Missouri Department of Health and Senior Services; Other
Eligibility: 60 Years to 100 Years
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Jefferson City, Missouri

Conditions: Gingival Recession, Mucogingival Deformity - Insufficient Keratinized Tissue
Interventions: Modified Coronally Advanced Tunnel with Connective Tissue Graft; Procedure
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years to 65 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Recession, Gingival
Interventions: Mandibular Incisor root coverage procedure; Procedure
Lead sponsor: Case Western Reserve University; Other
Eligibility: 18 Years and older
Enrollment: 36 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Gingivitis, Periodontitis
Interventions: ClōSYS® Sensitive Fluoride Toothpaste, ClōSYS® Sensitive Rinse; Drug · Other
Lead sponsor: Rowpar Pharmaceuticals, Inc.; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Mesa, Arizona

Conditions: Gingivitis
Interventions: Probiotics; Other
Lead sponsor: Sunstar Americas; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 62 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Cambridge, Massachusetts

Conditions: Dental Plaque, Gingivitis
Interventions: Triclosan/fluoride toothpaste, stannous fluoride toothpaste, fluoride only toothpaste, Cetylpyridinium chloride mouthwash, Fluoride only mouthwash; Drug
Lead sponsor: Colgate Palmolive; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 179 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014
U.S. locations: 1
States / cities: Cedar Knolls, New Jersey

Conditions: Periodontal Diseases, Periodontitis, Gum Disease
Interventions: Erchonia® FX405, Placebo Laser; Device
Lead sponsor: Erchonia Corporation; Industry
Eligibility: 22 Years to 75 Years
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 2
States / cities: Thousand Oaks, California • Acton, Massachusetts

Conditions: Bad Breath, Tooth Sensitivity
Interventions: Larineco Remineralizing Gum; Dietary Supplement
Lead sponsor: Larine C Corporation; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 1
States / cities: Las Vegas, Nevada

Conditions: Periodontal Diseases, Periodontitis, Apical, Chronic Nonsuppurative, Suppuration of Gingival Crevice
Interventions: Scaling and Root Planing, Diode Laser + Scaling and Root Planing; Procedure
Lead sponsor: University of Nebraska; Other
Eligibility: 30 Years and older
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Lincoln, Nebraska

Search by objective public record fields.

Clinical Research Study to Assess the Efficacy of Two Brushing Regimens in the Reduction of Established Dental Plaque and Gingivitis.

Philips AirFlosser Study

A Study to Determine the Effects of Adding an Experimental Device With Mouthrinse to Oral Care Regimen

Efficacy of Methods to Treat Multiple Gingival Recession Defects

Compare the Clinical Efficacy of Prototype Toothpastes.

Root Coverage With Acellular Dermal Matrix and Bovine Derived Osseous

Brief Title: a Clinical Study to Assess Gingivitis

Efficacy and Safety Study of Interproximal Cleaning Modalities on Oral Health

Evaluation of the Efficacy and Safety of a Loop Stretchable Dental Floss

Powertoothbrushing for Treating Gingivitis

A Study is to Evaluate a Regimen on Gingivitis Using Traditional and Novel Assessment Methods

A Clinical Study Investigating the Effects of a Dentifrice Containing 0.454% Stannous Fluoride on Gingivitis Treatment and Plaque Reduction When Used Twice Daily for 12 Weeks

Plaque Removal Efficacy of a U-Shaped Sonic Power Toothbrush in Children

Efficacy of Plaque Removal of a Novel Brushing Device

Experimental Peri-implant Mucositis in Humans

Extending Dental Care to Nursing Home Residents to Reduce Mouth Infections and Incidence of Pneumonia and Improve Diabetic Glucose Control

Modified Coronally Advanced Tunnel for Mandibular Lingual Root Coverage

Comparison of Two Methods of Covering a Single Lower Front Tooth With Receded Gums

Efficacy of ClōSYS® Sensitive Fluoride Toothpaste and ClōSYS® Sensitive Rinse Regimen on MGI, PI and BOP

A Clinical Trial to Evaluate Long-term Efficacy and Safety of Lozenges Containing Lactobacilli Reuteri (Prodentis™) on Gingivitis

Clinical Study Comparing Dental Plaque and Gingivitis Reduction After Using One of Three Oral Hygiene Multi-component Regimens (Using of a Manual Toothbrush, a Toothpaste and a Mouthwash)

An Evaluation of the Effect of the Erchonia FX-405 Laser as an Adjunctive Treatment of Periodontitis

A Clinical Trial to Evaluate the Effects of Larineco Remineralizing Gum on Oral Health, Breath Freshness, Tooth Sensitivity, and Gum Comfort

Diode Laser Study for Periodontal Maintenance Patients