- Conditions
- Granulin Mutation
- Interventions
- FRM-0334, Placebo
- Drug
- Lead sponsor
- FORUM Pharmaceuticals Inc
- Industry
- Eligibility
- 21 Years to 75 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2014
- U.S. locations
- 5
- States / cities
- San Francisco, California • Orlando, Florida • Boston, Massachusetts + 2 more
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Showing 1–5
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- Conditions
- Healthy, Frontotemporal Dementia
- Interventions
- AL001, Placebo
- Biological · Other
- Lead sponsor
- Alector Inc.
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 64 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2019
- U.S. locations
- 5
- States / cities
- Birmingham, Alabama • San Francisco, California • Orlando, Florida + 2 more
- Conditions
- Frontotemporal Dementia
- Interventions
- AL001
- Drug
- Lead sponsor
- Alector Inc.
- Industry
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 33 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2024
- U.S. locations
- 4
- States / cities
- San Francisco, California • Rochester, Minnesota • Philadelphia, Pennsylvania + 1 more
- Conditions
- Frontotemporal Dementia, FTD, FTD-GRN, Dementia, Frontotemporal
- Interventions
- Intrathalamic AAV.PGRN administration, Intrathalamic AVB-101
- Procedure · Genetic
- Lead sponsor
- AviadoBio Ltd
- Industry
- Eligibility
- 30 Years to 75 Years
- Enrollment
- 18 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2030
- U.S. locations
- 3
- States / cities
- Columbus, Ohio • Nashville, Tennessee • Houston, Texas
- Conditions
- Frontotemporal Dementia, FTD, FTD-GRN, Dementia Frontotemporal, C9orf72
- Interventions
- PBFT02
- Drug
- Lead sponsor
- Passage Bio, Inc.
- Industry
- Eligibility
- 35 Years to 75 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2031
- U.S. locations
- 4
- States / cities
- Ann Arbor, Michigan • Philadelphia, Pennsylvania • Nashville, Tennessee + 1 more