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Showing 1–15 of 15 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Guilt Clear all
Recruiting Not applicable Interventional

Healthy Recovery After Trauma Study

NCT04585685
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Shame, Guilt, Sexual Assault and Rape
Interventions
Cognitive Processing Therapy, Self-Compassion Therapy
Behavioral
Lead sponsor
Christal L Badour
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Nov 9, 2025 · Synced Jul 21, 2026, 4:01 PM EDT
Recruiting Not applicable Interventional

Trauma-Informed Guilt Reduction Therapy Compared to Prolonged Exposure

NCT06296589
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Trauma Informed Guilt Reduction Therapy, Prolonged Exposure Therapy
Behavioral
Lead sponsor
Veterans Medical Research Foundation
Other
Eligibility
18 Years and older
Enrollment
158 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
3
States / cities
Little Rock, Arkansas • New Orleans, Louisiana • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 21, 2025 · Synced Jul 21, 2026, 4:01 PM EDT
Not listed Phase 2 Interventional Accepts healthy volunteers

Jail-Based Impact of Crime Intervention

NCT01378936
View directory record Official record
Conditions
Substance Abuse, HIV Risk, Criminogenic Thinking, Shame, Guilt, Empathy
Interventions
MI plus IOC group intervention, Motivational Interview only
Behavioral
Lead sponsor
George Mason University
Other
Eligibility
18 Years and older · Male only
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2016
U.S. locations
1
States / cities
Fairfax, Virginia
Source: ClinicalTrials.gov public record
Updated May 6, 2013 · Synced Jul 21, 2026, 4:01 PM EDT
Completed Not applicable Interventional Results available

Technology and Family Thriving Study

NCT05150990
View directory record Official record
Conditions
Alzheimer Disease, Dementia, Caregiver Burnout, Quality of Life, Mental Health Wellness 1, Loneliness, Family Relationship
Interventions
Virtual Reality, Video Chat
Behavioral
Lead sponsor
University of California, Santa Barbara
Other
Eligibility
18 Years and older
Enrollment
186 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
27
States / cities
Calabasas, California • Camarillo, California • Goleta, California + 16 more
Source: ClinicalTrials.gov public record
Updated Jul 14, 2025 · Synced Jul 21, 2026, 4:01 PM EDT
Completed Not applicable Interventional

Psychotherapy Treatment of Deployment-Related PTSD in Primary Care Settings

NCT00974402
View directory record Official record
Conditions
Post-Traumatic Stress Disorders, Stress Disorders, Combat Disorders
Interventions
Cognitive Behavioral Therapy
Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
3
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Sep 17, 2014 · Synced Jul 21, 2026, 4:01 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Dose Escalation, Double-Blind Treatment With Duloxetine Hydrochloride Once Daily Dosing for Evaluation of Safety in Major Depression

NCT00042575
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Duloxetine
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002
U.S. locations
9
States / cities
Trumbull, Connecticut • Lafayette, Indiana • Gaithersburg, Maryland + 6 more
Source: ClinicalTrials.gov public record
Updated Jul 18, 2006 · Synced Jul 21, 2026, 4:01 PM EDT
Active, not recruiting Not applicable Interventional

Non-Inferiority Trial of TrIGR for PTSD

NCT05789329
View directory record Official record
Conditions
PTSD
Interventions
Trauma Informed Guilt Reduction Therapy, Cognitive Processing Therapy
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
2
States / cities
San Diego, California • Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jun 28, 2026 · Synced Jul 21, 2026, 4:01 PM EDT
Completed Not applicable Interventional

A Ten-Week Online Acceptance and Commitment Therapy Intervention for Family Caregivers of People With Dementia

NCT05043441
View directory record Official record
Conditions
Depressive Symptoms
Interventions
Acceptance and commitment therapy (ACT), Psychoeducation
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 8, 2024 · Synced Jul 21, 2026, 4:01 PM EDT
Terminated Not applicable Interventional

Effectiveness of Compassion Focused Therapy (CFT)

NCT05044715
View directory record Official record
Conditions
Compassion, Self-Criticism, Shame, Guilt
Interventions
Treatment as Usual, Compassion-Focused Therapy (CFT)
Behavioral
Lead sponsor
Brigham Young University
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Provo, Utah
Source: ClinicalTrials.gov public record
Updated Jun 8, 2023 · Synced Jul 21, 2026, 4:01 PM EDT
Completed Phase 3 Interventional

Open-Label Treatment With Duloxetine Hydrochloride Once-Daily Dosing for Evaluation of Stabilization Dose in Patients With Major Depression

NCT00042562
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
duloxetine
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2003
U.S. locations
23
States / cities
Carlsbad, California • Los Angeles, California • Stanford, California + 20 more
Source: ClinicalTrials.gov public record
Updated Jul 18, 2006 · Synced Jul 21, 2026, 4:01 PM EDT
Completed Not applicable Interventional

Guided Eight-week Online Acceptance and Commitment Therapy for Distressed Family Caregivers of People With Dementia

NCT04847986
View directory record Official record
Conditions
Psychological Distress
Interventions
acceptance and commitment therapy (ACT), Control group
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 27, 2022 · Synced Jul 21, 2026, 4:01 PM EDT
Not listed Phase 1Phase 2 Interventional

Trial of Impact of Crime Group Intervention for Jail Inmates

NCT01380977
View directory record Official record
Conditions
Crime, Substance Abuse, HIV Risk, Criminogenic Thinking, Shame
Interventions
Impact of Crime group intervention
Behavioral
Lead sponsor
George Mason University
Other
Eligibility
18 Years and older · Male only
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2016
U.S. locations
1
States / cities
Fairfax, Virginia
Source: ClinicalTrials.gov public record
Updated May 6, 2013 · Synced Jul 21, 2026, 4:01 PM EDT
Withdrawn Not applicable Interventional

Videoconferencing Acceptance and Commitment Therapy With a Web App Use for Family Caregivers of People With Dementia

NCT05518968
View directory record Official record
Conditions
Depression
Interventions
Acceptance and commitment therapy
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 4, 2024 · Synced Jul 21, 2026, 4:01 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Victim Impact Modules for Jail Inmates

NCT01381146
View directory record Official record
Conditions
Substance Abuse, HIV Risk, Shame, Guilt, Empathy, Criminogenic Thinking
Interventions
Impact of Crime Modules, TAU
Behavioral
Lead sponsor
George Mason University
Other
Eligibility
18 Years and older · Male only
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Fairfax, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 24, 2017 · Synced Jul 21, 2026, 4:01 PM EDT
Completed Not applicable Interventional Results available

Trauma Informed Guilt Reduction Therapy

NCT02512445
View directory record Official record
Conditions
Guilt, Shame, Post-traumatic Stress Disorders
Interventions
Trauma Informed Guilt Reduction Therapy, Supportive Care Therapy
Behavioral
Lead sponsor
Veterans Medical Research Foundation
Other
Eligibility
18 Years and older
Enrollment
145 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2023
U.S. locations
3
States / cities
San Diego, California • Boston, Massachusetts • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 8, 2025 · Synced Jul 21, 2026, 4:01 PM EDT