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Showing 25–45 of 21 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Gum Recession Clear all
Withdrawn Not applicable Interventional Accepts healthy volunteers

Root Coverage Comparing an Allograft to a Bovine Xenograft

NCT02810067
View directory record Official record
Conditions
Gingival Recession
Interventions
Tunnel + AlloDerm, Tunnel + Novomatrix
Procedure
Lead sponsor
University of Louisville
Other
Eligibility
18 Years to 120 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 17, 2018 · Synced Jul 22, 2026, 6:54 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

A Comparison of Side Access Mucosal Releasing Incision (SAMRI) and Sulcular Tunnel Access to Treat Gingival Recession.

NCT04179448
View directory record Official record
Conditions
Gingival Recession, Lack of Keratinized Gingiva
Interventions
SAMRI, STA
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 99 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Jul 22, 2026, 6:54 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Palatal Wound Healing After Free Gingival Graft Harvest in Diabetic Patients: A Clinical Trial

NCT07500935
View directory record Official record
Conditions
Diabetes Mellitus, Gingival Recession, Generalized, Gingival Recession, Localized
Interventions
Free gingival graft
Procedure
Lead sponsor
Mauro Santamaria
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Jul 22, 2026, 6:54 PM EDT
Recruiting Not applicable Interventional

Patient-reported Outcomes of Donor Site Healing Using Different Palatal Protection Techniques

NCT06892496
View directory record Official record
Conditions
Mucosal Erosion, Gingival Recession
Interventions
Visual Analog scale (VAS) questionnaire, Vacuum-formed retainer (VFR) technique, 3-D printed acrylic resin stent (3DS) technique, Flowable resin composite stent (FRC) technique, Photographs of the patient's palate, Measuring graft dimensions, Chairside Polymer Stent
Other
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Jul 22, 2026, 6:54 PM EDT
Active, not recruiting Phase 4 Interventional Accepts healthy volunteers

Microderm for Root Coverage Procedures

NCT07203326
View directory record Official record
Conditions
Connective Tissue Graft, Gum Recession
Interventions
Alloderm, MicroDerm
Biological
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 25, 2025 · Synced Jul 22, 2026, 6:54 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Palatal Volumetric Change Analysis Following Connective Tissue Graft With and Without Donor Site Augmentation

NCT05961566
View directory record Official record
Conditions
Recession, Gingival
Interventions
Use of collagen matrix after subepithelial connective tissue graft harvest
Device
Lead sponsor
Hailey Bivens
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 18, 2024 · Synced Jul 22, 2026, 6:54 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Root Coverage Using ADM and Coronally Positioned Tunnel With or Without Enamel Matrix Derivative

NCT05565079
View directory record Official record
Conditions
Recession, Gingival
Interventions
Regenerative tissue matrix and enamel matrix derivative, Regenerative tissue matrix
Biological
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Jul 22, 2026, 6:54 PM EDT
Not yet recruiting Not applicable Interventional

Modified Coronally Advanced Tunnel for Mandibular Lingual Root Coverage

NCT07590960
View directory record Official record
Conditions
Gingival Recession, Mucogingival Deformity - Insufficient Keratinized Tissue
Interventions
Modified Coronally Advanced Tunnel with Connective Tissue Graft
Procedure
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Jul 22, 2026, 6:54 PM EDT
Completed Not applicable Interventional

A Pilot Clinical Trial of Gintuit (TM)in Establishing a Functional Zone of Attached Gingiva

NCT01547962
View directory record Official record
Conditions
Gingival Recession
Interventions
Gintuit, autologous Free Gingival Graft (FGG)
Device · Other
Lead sponsor
Organogenesis
Industry
Eligibility
18 Years to 70 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 8, 2012 · Synced Jul 22, 2026, 6:54 PM EDT
Completed Phase 4 Interventional

Pilot Study for Healing and Safety Outcomes in Gingival Recession

NCT04614350
View directory record Official record
Conditions
Gingival Recession
Interventions
Markman Biologics Microsurfaced ADM, AlloDerm
Biological
Lead sponsor
McGuire Institute
Industry
Eligibility
18 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 23, 2022 · Synced Jul 22, 2026, 6:54 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Platelet Rich Fibrin and Autologous Fibrin Glue

NCT03734458
View directory record Official record
Conditions
Gingival Recession
Interventions
Group A - PRF plus AFG with a CAF, Group B - PRF only with a CAF, Group C - CTG with a CAF
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 7, 2019 · Synced Jul 22, 2026, 6:54 PM EDT
Completed Not applicable Interventional Results available

Expression of Angiogenic Biomarkers During Healing of Intra-Oral Soft Tissue Engineered Grafts

NCT01134081
View directory record Official record
Conditions
Gingival Recession
Interventions
CelTx™, Free Gingival Graft
Biological · Procedure
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 20, 2017 · Synced Jul 22, 2026, 6:54 PM EDT
Completed Not applicable Interventional

Pinhole Surgical Technique Compared to Connective Tissue Graft in Treatment of Gingival Recession

NCT04356391
View directory record Official record
Conditions
Periodontal Diseases
Interventions
Connective Tissue Graft Technique, Pinhole Surgical Technique
Procedure
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
19 Years and older
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated May 24, 2023 · Synced Jul 22, 2026, 6:54 PM EDT
Completed Not applicable Interventional Results available

Study of Root Coverage With Acellular Dermal Matrix: Puros® Dermis Versus Alloderm®

NCT00881959
View directory record Official record
Conditions
Gingival Recession
Interventions
Puros® Dermis versus Alloderm®
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
4
States / cities
Birmingham, Alabama • Ann Arbor, Michigan • Newark, New Jersey + 1 more
Source: ClinicalTrials.gov public record
Updated May 26, 2015 · Synced Jul 22, 2026, 6:54 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Root Coverage Using a Xenograph for Treatment of Gingival Recession

NCT02657395
View directory record Official record
Conditions
Localized Gingival Recession
Interventions
PriMatrix
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 90 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 24, 2017 · Synced Jul 22, 2026, 6:54 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Progenitor Potential of Mesenchymal Stem Cells in Palatal Tissue Harvested From Molar and Premolar Sites

NCT03570333
View directory record Official record
Conditions
Gingival Recession, Lack of Keratinized Gingiva (Disorder)
Interventions
progenitor potential of Gingival Mesenchymal cells
Diagnostic Test
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 70 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2025
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Dec 18, 2025 · Synced Jul 22, 2026, 6:54 PM EDT
Completed No phase listed Observational

Facial Mucosal Level Determinants for Single Immediately Placed Implants Evaluated by Novel Ultrasonography

NCT03558282
View directory record Official record
Conditions
Gingival Recession
Interventions
Recession Observation, Crown Contour Observation
Other · Diagnostic Test
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 14, 2019 · Synced Jul 22, 2026, 6:54 PM EDT
Recruiting No phase listed Observational

Taking Measurements of a Gum Graft Site as it Heals

NCT07386457
View directory record Official record
Conditions
Gingival Recession
Interventions
Gingival graft surgery to treat gingival recession
Procedure
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 50 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 19, 2026 · Synced Jul 22, 2026, 6:54 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pinhole Versus Tunnel for Soft Tissue Recession

NCT04513041
View directory record Official record
Conditions
Gingival Recession
Interventions
Pinhole surgical technique and tunnel technique in a split mouth design
Procedure
Lead sponsor
Mohanad Al-Sabbagh
Other
Eligibility
18 Years to 75 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Jul 22, 2026, 6:54 PM EDT
Not listed No phase listed Observational

Collagen Matrix With and Without Enamel Matrix Derivative

NCT03467802
View directory record Official record
Conditions
Gingival Recession
Interventions
enamel matrix derivative, Porcine collagen matrix
Biological · Device
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
18 Years and older
Enrollment
30 participants
Timeline
2019 – 2021
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 30, 2019 · Synced Jul 22, 2026, 6:54 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

To Compare Two Commonly Used Soft Tissue Grafting Techniques to Achieve Coronal Flap Advancement and Root Coverage

NCT03566108
View directory record Official record
Conditions
Gingival Recession
Interventions
VISTA, STA
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 99 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Nov 17, 2024 · Synced Jul 22, 2026, 6:54 PM EDT