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ClinicalTrials.gov public records Last synced Oct 6, 2026, 2:41 PM EDT

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Showing 25–45 of 45 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Gut Dysbiosis Clear all
Completed Not applicable Interventional

The Use of A Prebiotic to Promote a Healthy Gut Microbiome in Pediatric Stem Cell Transplant Recipients

NCT04111471
View directory record Official record
Conditions
Microbial Colonization
Interventions
Prebiotics, Placebos
Dietary Supplement
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
2 Years to 18 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 21, 2024 · Synced Oct 6, 2026, 2:41 PM EDT
Not yet recruiting Phase 2 Interventional

Herbal Supplement (Biocidin REMOVE) for Bacterial Overgrowth in Irritable Bowel Syndrome

NCT07768267
View directory record Official record
Conditions
Irritable Bowel Syndrome (IBS), Small Intestinal Bacterial Overgrowth Syndrome (SIBO)
Interventions
Biocidin REMOVE, Placebo
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 4, 2026 · Synced Oct 6, 2026, 2:41 PM EDT
Completed Phase 1 Interventional

Vitamin D Regulation of Gut Specific B Cells and Antibodies Targeting Gut Bacteria in Inflammatory Bowel Disease

NCT04828031
View directory record Official record
Conditions
Inflammatory Bowel Diseases, Ulcerative Colitis, Crohn Disease
Interventions
Vitamin D
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Sep 21, 2023 · Synced Oct 6, 2026, 2:41 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Exercise, Hypertension, and Gut Dysbiosis in African Americans

NCT03897777
View directory record Official record
Conditions
Hypertension
Interventions
Exercise Training effect on Hypertension and Gut Dysbiosis
Behavioral
Lead sponsor
North Carolina Agriculture & Technical State University
Other
Eligibility
30 Years to 50 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2030
U.S. locations
1
States / cities
Greensboro, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 6, 2026, 2:41 PM EDT
Completed Early Phase 1 Interventional

Bacterial Intestinal Gut Modification Around Cancer Surgery (BIG MACS) Diet

NCT05658263
View directory record Official record
Conditions
Dysbiosis, Sarcopenia, Colon Cancer
Interventions
Standard Diet, BIG MACS Diet
Dietary Supplement
Lead sponsor
University of Minnesota
Other
Eligibility
25 Years to 70 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated May 13, 2025 · Synced Oct 6, 2026, 2:41 PM EDT
Active, not recruiting No phase listed Observational

REMBRANDT: REcovery of the MicroBiome fRom Antibiotics for Dental implanTs

NCT05622721
View directory record Official record
Conditions
Dysbiosis, Clostridium Difficile, Pet-Human Bonding, Antibiotic-Associated Colitis
Interventions
Not listed
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Oct 6, 2026, 2:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Gut-level Antiinflammatory Activities of Green Tea in Metabolic Syndrome

NCT03973996
View directory record Official record
Conditions
Dysbiosis, Endotoxemia, Metabolic Syndrome, Inflammation
Interventions
Green Tea Extract, Placebo
Dietary Supplement
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 65 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 19, 2025 · Synced Oct 6, 2026, 2:41 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Pulse Education and Children

NCT07648446
View directory record Official record
Conditions
Dysbiosis, Cardiometabolic Health Indicators, Education on Feeding and Health Status, Gut Motility
Interventions
Education Only, Education + Pulse Provision, Cooking Class
Other
Lead sponsor
Florida State University
Other
Eligibility
6 Years to 13 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Oct 6, 2026, 2:41 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Alcohol Misuse, Gut Microbial Dysbiosis and PrEP Care Continuum: Application and Efficacy of SBIRT Intervention

NCT06005298
View directory record Official record
Conditions
Alcohol Use Disorder, Risk Behavior, Health, Dysbiosis, HIV Infections
Interventions
Screening, Brief Intervention, Referral to Treatment (SBIRT)
Behavioral
Lead sponsor
Shirish S Barve
Other
Eligibility
18 Years to 85 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Jul 22, 2024 · Synced Oct 6, 2026, 2:41 PM EDT
Completed Not applicable Interventional

A Trial of a Multi-Component Nutritional Supplement in Hydrogen-Dominant Small Intestinal Bacterial Overgrowth

NCT07215676
View directory record Official record
Conditions
Small Intestinal Bacterial Overgrowth Syndrome (SIBO), Small Intestinal Bacterial Overgrowth
Interventions
AV1PD1A
Dietary Supplement
Lead sponsor
National University of Natural Medicine
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated May 12, 2026 · Synced Oct 6, 2026, 2:41 PM EDT
Completed Phase 4 Interventional Results available

Vitamin D and Prebiotics for Intestinal Health in Cystic Fibrosis

NCT04118010
View directory record Official record
Conditions
Cystic Fibrosis, Dysbiosis
Interventions
Vitamin D3, Placebo vitamin D3, Inulin, Placebo Inulin
Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 7, 2024 · Synced Oct 6, 2026, 2:41 PM EDT
Active, not recruiting Not applicable Interventional

A Study of Healthy Microbiome, Healthy Mind

NCT06020703
View directory record Official record
Conditions
Critical Illness, COVID-19, PICS, Cognitive Impairment, Mental Health Impairment, Weakness, Muscle, Dysbiosis
Interventions
Fermented Food Diet
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Oct 6, 2026, 2:41 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Factors Mediating Gut Microbiota Dysbiosis and Metabolic Disease in HIV Patients.

NCT02258685
View directory record Official record
Conditions
HIV, Lipodystrophy
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 65 Years
Enrollment
93 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 18, 2019 · Synced Oct 6, 2026, 2:41 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Pilot Study Assessing Intestinal Microbiota Diversification and Changes After Travel to South(East) Asia From the US

NCT03043300
View directory record Official record
Conditions
Dysbiosis
Interventions
Screening Criteria Review, Pre-Travel Questionnaire, Pre-Travel Stool Specimen Collection, Short-Term Post-Travel Questionnaire, Short-Term Post-Travel Stool Specimen Collection, Long-Term Post-Travel Questionnaire, Long-Term Post-Travel Stool Specimen Collection
Other
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
2
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 30, 2019 · Synced Oct 6, 2026, 2:41 PM EDT
Completed Not applicable Interventional Results available

Multisensory Early Oral Administration of Human Milk in Preterm Infants

NCT06230848
View directory record Official record
Conditions
Infant Development, Stress
Interventions
Multisensory Early Oral Administration of Human Milk (M-MILK)
Other
Lead sponsor
Loyola University
Other
Eligibility
0 Years to 1 Year
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Maywood, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 8, 2026 · Synced Oct 6, 2026, 2:41 PM EDT
Completed Phase 1 Interventional

Fecal Microbiota Transplantation in HIV

NCT02256592
View directory record Official record
Conditions
HIV
Interventions
Fecal Microbiota
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 75 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 4, 2017 · Synced Oct 6, 2026, 2:41 PM EDT
Completed Not applicable Interventional

Influences of High-fiber, Organic Whole-food Formula on the Gut Microbiome in Critically Ill Children

NCT03414775
View directory record Official record
Conditions
Critical Illness, Dysbiosis, Pediatric ALL
Interventions
Nourish, Pediasure
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
1 Year to 17 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 12, 2026 · Synced Oct 6, 2026, 2:41 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Effect of Lentils and Chickpeas on Gut Microbiome and Metabolic Health

NCT06914375
View directory record Official record
Conditions
Dysbiosis
Interventions
Goya Foods - Canned Chickpeas, Goya Foods - Canned Lentils, Control
Other
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 30 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 6, 2026, 2:41 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Almonds, Gut Microbiome and Kids

NCT07636850
View directory record Official record
Conditions
Dysbiosis, Cardiometabolic Health Indicators
Interventions
Creamy Richards 100% Almonds! Creamy Natural Almond Butter, Cadbury Milk Chocolate Spread
Other
Lead sponsor
Florida State University
Other
Eligibility
6 Years to 13 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Oct 6, 2026, 2:41 PM EDT
Recruiting Early Phase 1 Interventional

Cranberry and Gut Health in Crohn's Disease

NCT07170462
View directory record Official record
Conditions
Crohn Disease (CD), Crohn Disease
Interventions
Cranberry powder, Placebo
Drug · Dietary Supplement
Lead sponsor
Ana Maldonado-Contreras
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Oct 6, 2026, 2:41 PM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Human Milk Oligosaccharide-Based Synbiotic Supplement for Intestinal Microbiota Dysbiosis

NCT06615986
View directory record Official record
Conditions
Healthy Volunteers
Interventions
Cardiosyn
Dietary Supplement
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
18 Years to 99 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Oct 6, 2026, 2:41 PM EDT