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ClinicalTrials.gov public records Last synced Nov 15, 2026, 9:41 AM EST

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Showing 49–72 of 72 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Gut Permeability Clear all

Conditions: Diarrhea-Predominant Irritable Bowel Syndrome
Interventions: Glutamine; Drug
Lead sponsor: Tulane University; Other
Eligibility: 18 Years to 72 Years
Enrollment: 106 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2015
U.S. locations: 1
States / cities: New Orleans, Louisiana

Conditions: Gastrointestinal Disorders
Interventions: Gluten Healthy, Placebo; Dietary Supplement · Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 70 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Gut Health
Interventions: Butyrate Formulation, Butyrate + Polyphenol Formulation, Placebo; Dietary Supplement
Lead sponsor: Supplement Formulators, Inc.; Industry
Eligibility: 21 Years to 70 Years
Enrollment: 143 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Fort Lauderdale, Florida

Conditions: Functional Dyspepsia
Interventions: Not listed
Lead sponsor: Children's Mercy Hospital Kansas City; Other
Eligibility: 8 Years to 17 Years
Enrollment: 42 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2010
U.S. locations: 1
States / cities: Kansas City, Missouri

Conditions: Eosinophilic Esophagitis
Interventions: Absorbable sugars; Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 80 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Endometriosis
Interventions: lactulose:mannitol (L:M) oral challenge; Drug
Lead sponsor: University of Tennessee; Other
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 46 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2019
U.S. locations: 2
States / cities: Chattanooga, Tennessee

Conditions: Functional Dyspepsia
Interventions: Glutamine, Placebo; Drug
Lead sponsor: David J. Cangemi; Other
Eligibility: 18 Years to 75 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Inflammation
Interventions: Juice Plus+, Placebo; Dietary Supplement · Other
Lead sponsor: University of Memphis; Other
Eligibility: 25 Years to 50 Years · Female only
Enrollment: 57 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Memphis, Tennessee

Conditions: Exercise and Gut-derived Phenolics
Interventions: Flavonoid supplement, Placebo; Dietary Supplement
Lead sponsor: Appalachian State University; Other
Eligibility: 18 Years to 50 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017
U.S. locations: 1
States / cities: Kannapolis, North Carolina

Conditions: Healthy
Interventions: Small Bowel and Colonic Permeability Test; Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 70 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Arterial Stiffness, Blood Pressure, Dysbiosis, Inflammation, Permeability; Increased
Interventions: Freeze-dried grape powder, Placebo powder; Dietary Supplement · Other
Lead sponsor: University of California, Davis; Other
Eligibility: 45 Years to 70 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Davis, California

Conditions: Autism, Inflammation
Interventions: Stool collection, Administration of carbohydrate solution during clinically indicated endoscopy, Questionnaires; Other
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Months to 17 Years
Enrollment: 115 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2017
U.S. locations: 2
States / cities: Boston, Massachusetts • Newton, Massachusetts

Conditions: Short Bowel Syndrome
Interventions: Teduglutide, Placebo; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 75 Years
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Gastrointestinal Dysfunction, Metabolic Disturbance
Interventions: High Dose Hemp Fiber Bar, Low Dose Hemp Fiber Bar, Placebo; Dietary Supplement
Lead sponsor: Appalachian State University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Kannapolis, North Carolina

Conditions: Aging, Diet, Healthy
Interventions: Western Diet; Other
Lead sponsor: University of Delaware; Other
Eligibility: 50 Years to 64 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Newark, Delaware

Conditions: Intestinal Permeability, Gastrointestinal Function
Interventions: Cranberry Beverage, Control Beverage; Other
Lead sponsor: University of Florida; Other
Eligibility: 21 Years to 50 Years
Enrollment: 43 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Prematurity, Intestinal Permeability
Interventions: Lactulose -rhamnose solution; Drug
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: Up to 4 Days
Enrollment: 211 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2021
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Cardiometabolic Health Indicators, Vascular Function in Healthy Volunteers, Inflammation
Interventions: Ataulfo mango; Other
Lead sponsor: University of California, Davis; Other
Eligibility: 12 Years to 19 Years
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Davis, California

Conditions: Mild Cognitive Impairment, Alzheimer Disease (AD), Dementia
Interventions: Not listed
Lead sponsor: University of South Florida; Other
Eligibility: 18 Years and older
Enrollment: 700 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2031
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Colorectal Cancer, Tumor, CRC, GI Cancer, Gastrointestinal Cancer
Interventions: Not listed
Lead sponsor: Viome; Industry
Eligibility: 50 Years to 80 Years
Enrollment: 63 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022
U.S. locations: 1
States / cities: Bellevue, Washington

Conditions: Prematurity Complications
Interventions: measurement of intestinal permeability; Drug
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: Up to 4 Days
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Chronic Kidney Disease
Interventions: Vitamin D3; Drug
Lead sponsor: Rockefeller University; Other
Eligibility: 50 Years to 80 Years
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: New York, New York

Conditions: Irritable Bowel Syndrome, Diarrhea
Interventions: Colesevelam, Placebo; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 65 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: HIV
Interventions: Lubiprostone; Drug
Lead sponsor: Ruth M. Rothstein CORE Center; Other
Eligibility: 18 Years to 65 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Chicago, Illinois

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Glutamine for the Treatment of Patients With Irritable Bowel Syndrome

Change in Permeability of the Small Intestine After Treatment With Gluten

Effectiveness of a Butyrate Formulation and Butyrate + Polyphenol Formulation on Gut Health, Permeability and Associated Symptoms

Intestinal Permeability in Children/Adolescents With Functional Dyspepsia

Intestinal Permeability in Response to Treatment in Eosinophilic Esophagitis Patients

Intestinal Permeability and Endometriosis

A Study of Glutamine to Treat Intestinal Permeability in Functional Dyspepsia

Impact of JuicePlus+ on the Health Status of an Overweight Stressed Population

Flavonoids, Exercise, Gut-Derived Phenolics

Standardizing Method and Development of Normal Values to Measure Human Small Intestinal and Colonic Permeability

Prebiotic Effects of California Grapes on Gut Health and Cardiometabolic Health in Overweight Men and Women

Intestinal Inflammation and Carbohydrate Digestion in Autistic Children

Short Bowel Syndrome and Teduglutide Versus Placebo

Hemp Fiber Ingestion and Gut Permeability After Exercise

Western Diet on Cardiometabolic and Immune Function

The Effect of a Cranberry Beverage on Intestinal Permeability and Gastrointestinal Function in Generally Healthy Adults

Intestinal Permeability in Preterm Infants

Mango Intake and Gut and Cardiometabolic Health in Hispanic/Latino Adolescents

Microbiome in Aging of Gut and Brain

Microbiome in Colorectal Cancer Onset and Progression

Gut Permeability and Microbiome in Preterm Infants

Vitamin D Repletion in Chronic Kidney Disease

Does Welchol (Colesevelam Hydrochloride) Improve Colonic Transit in Diarrhea-predominant Irritable Bowel Syndrome (D-IBS)?

Lubiprostone as a Modulator of Gut Microbial Translocation in HIV With Incomplete CD4 Recovery on Antiretroviral Therapy