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Showing 1–24 of 165 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: HIV/AIDS, Medication Adherence Clear all
Completed Phase 1 Interventional

Therapeutic Drug Monitoring and Viral Resistance Testing in the Treatment of HIV-Infected Children

NCT00032669
View directory record Official record
Conditions
HIV Infections
Interventions
HAART
Drug
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
Not listed
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2006
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Sep 15, 2026, 10:38 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Feasibility, Acceptability, and Preliminary Efficacy of an HIV Prevention Intervention for Older Black Women

NCT07181616
View directory record Official record
Conditions
Health Risk Behaviors
Interventions
Adapted W2W, Waitlist Control
Behavioral
Lead sponsor
Laneshia Conner
Other
Eligibility
50 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Sep 15, 2026, 10:38 AM EDT
Completed Not applicable Interventional

Mobile Health Application to Improve HIV Medication Adherence

NCT02676128
View directory record Official record
Conditions
HIV, Medication Adherence, Mobile Health
Interventions
Twine Collaborative Care Application, Information-Motivation-Behavioral Skills Model of ART Adherence
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 5, 2020 · Synced Sep 15, 2026, 10:38 AM EDT
Not yet recruiting Not applicable Interventional

Addressing Barriers to Anti-hypertensive Medication Adherence Among PLWH Who Have Achieved Viral Suppression

NCT05459077
View directory record Official record
Conditions
Hypertension, HIV-1-infection
Interventions
Hypertension control through education and monitoring
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Sep 15, 2026, 10:38 AM EDT
Completed Phase 3 Interventional

The Effect of Teaching HIV-Infected Patients About HIV and Treatment

NCT00002409
View directory record Official record
Conditions
HIV Infections
Interventions
Lamivudine/Zidovudine, Abacavir sulfate
Drug
Lead sponsor
Glaxo Wellcome
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
25
States / cities
Los Angeles, California • Oakland, California • Washington D.C., District of Columbia + 16 more
Source: ClinicalTrials.gov public record
Updated Jun 23, 2005 · Synced Sep 15, 2026, 10:38 AM EDT
Not listed Phase 1 Interventional

An Electronic Pillbox for People With HIV

NCT00071500
View directory record Official record
Conditions
HIV Infections
Interventions
MedSignals™
Device
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2009
U.S. locations
1
States / cities
Santa Barbara, California
Source: ClinicalTrials.gov public record
Updated Sep 25, 2008 · Synced Sep 15, 2026, 10:38 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Single Dose Truvada Study

NCT03719053
View directory record Official record
Conditions
Medication Adherence, HIV Prevention
Interventions
Tenofovir
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 15, 2020 · Synced Sep 15, 2026, 10:38 AM EDT
Completed Phase 3 Interventional

Next Generation Ingestible Sensors for Medication Adherence Measurement

NCT05592613
View directory record Official record
Conditions
HIV Infection, Adherence, Medication, Adherence, Treatment, Pre-Exposure Prophylaxis, Antiretroviral Therapy
Interventions
Next-generation Reader and ID-Cap System, Truvada for pre-exposure prophylaxis (PrEP), Biktarvy for antiretroviral therapy (ART)
Device · Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 24, 2024 · Synced Sep 15, 2026, 10:38 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Comparing Mobile Health Strategies to Improve Pre-exposure Prophylaxis Use (PrEP) for HIV Prevention

NCT04855773
View directory record Official record
Conditions
HIV Infections, Sexually Transmitted Diseases
Interventions
PrEPmate, Dot Diary
Other · Device
Lead sponsor
Public Health Foundation Enterprises, Inc.
Other
Eligibility
15 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
4
States / cities
San Francisco, California • Washington D.C., District of Columbia • Miami, Florida
Source: ClinicalTrials.gov public record
Updated Sep 27, 2022 · Synced Sep 15, 2026, 10:38 AM EDT
Completed Not applicable Interventional Results available

Secondary HIV Prevention and Adherence Among HIV-infected Drug Users

NCT01741311
View directory record Official record
Conditions
Risk Behavior, Medication Adherence, HIV
Interventions
3H+ (Holistic Health for HIV), HHRP+ (Holistic Health Recovery Program)
Behavioral
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years and older
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 7, 2025 · Synced Sep 15, 2026, 10:38 AM EDT
Active, not recruiting Not applicable Interventional

Promoting HIV Risk Reduction Among People Who Inject Drugs: A Stepped Care Approach Using Contingency Management With PrEP Adherence and Support Services

NCT04738825
View directory record Official record
Conditions
Opioid-use Disorder, HIV Prevention Program
Interventions
Contingency Management with stepped care to PrEP adherence and support services (CoMPASS)
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
526 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
6
States / cities
Bridgeport, Connecticut • Danbury, Connecticut • New Haven, Connecticut + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Sep 15, 2026, 10:38 AM EDT
Completed Not applicable Interventional

Improving Antiretroviral Medication Adherence Among HIV-infected Youth

NCT01347437
View directory record Official record
Conditions
HIV Infection
Interventions
Positive STEPS
Behavioral
Lead sponsor
Fenway Community Health
Other
Eligibility
13 Years to 24 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
3
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 16, 2017 · Synced Sep 15, 2026, 10:38 AM EDT
Not listed Not applicable Interventional

Stress-Reducing Interventions in HIV+ Patients: Pilot

NCT00599599
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, HIV Infections
Interventions
Prolonged Exposure Therapy
Behavioral
Lead sponsor
Kent State University
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
2
States / cities
Akron, Ohio • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 4, 2009 · Synced Sep 15, 2026, 10:38 AM EDT
Completed Not applicable Interventional

Managing Medications

NCT00222716
View directory record Official record
Conditions
HIV Infections
Interventions
Problem solving counseling
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
349 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 25, 2017 · Synced Sep 15, 2026, 10:38 AM EDT
Completed Not applicable Interventional

Electronic Intervention for HIV Medication Adherence

NCT01291485
View directory record Official record
Conditions
HIV
Interventions
Life Steps for Medication Adherence
Behavioral
Lead sponsor
Oklahoma State University Center for Health Sciences
Other
Eligibility
18 Years and older
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Oct 9, 2012 · Synced Sep 15, 2026, 10:38 AM EDT
Completed Not applicable Interventional

A Study of Two Adherence Plans to Help HIV-Positive Patients Take Their Medications Correctly

NCT00001129
View directory record Official record
Conditions
HIV Infections
Interventions
Electronic Medication Reminder System, Medication Manager
Device · Behavioral
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
Not listed
Enrollment
1,248 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2003
U.S. locations
20
States / cities
San Francisco, California • Denver, Colorado • New Haven, Connecticut + 14 more
Source: ClinicalTrials.gov public record
Updated Sep 30, 2013 · Synced Sep 15, 2026, 10:38 AM EDT
Completed Not applicable Interventional

Promoting Adherence to Anti-HIV Drug Regimens

NCT00051805
View directory record Official record
Conditions
HIV Infections
Interventions
Promotion of adherence to ARV medications
Behavioral
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
19 Years and older
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2006
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 17, 2007 · Synced Sep 15, 2026, 10:38 AM EDT
Completed Not applicable Interventional

Improving Drug Adherence Among Adolescents in Uganda Using SMS Reminders

NCT02128087
View directory record Official record
Conditions
Human Immunodeficiency Virus
Interventions
Two-way SMS intervention, One-way SMS intervention group
Behavioral
Lead sponsor
RAND
Other
Eligibility
15 Years to 24 Years
Enrollment
330 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Apr 13, 2017 · Synced Sep 15, 2026, 10:38 AM EDT
Completed Not applicable Interventional

Cell Phone Reminders Intervention

NCT01049568
View directory record Official record
Conditions
HAART Non-Adherence, HIV, HIV Infections
Interventions
Cell Phone Intervention
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
15 Years to 24 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
5
States / cities
Los Angeles, California • San Francisco, California • Washington D.C., District of Columbia + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 27, 2017 · Synced Sep 15, 2026, 10:38 AM EDT
Withdrawn Not applicable Interventional

mHealth Facilitated Intervention to Improve HIV Pre-Exposure Prophylaxis Adherence

NCT04990583
View directory record Official record
Conditions
Pre-Exposure Prophylaxis, Telemedicine, Medication Adherence
Interventions
Face-to-Face PrEP Adherence Intervention Based on LifeSteps, Adherence Coaching Facilitated by Carium Adherence App
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Apr 4, 2023 · Synced Sep 15, 2026, 10:38 AM EDT
Completed Not applicable Interventional

Medication Adherence and Outcomes Among Patients in United States With HIV

NCT03995745
View directory record Official record
Conditions
Human Immunodeficiency Virus, Medication Adherence
Interventions
Medication adherence and financial incentives
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 18, 2020 · Synced Sep 15, 2026, 10:38 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Project ADHERE: Clinical Proof-of-Concept of a Tenofovir (TFV) Aptamer-Based Biosensor

NCT04870671
View directory record Official record
Conditions
HIV/AIDS, Adherence, Medication, Drug Use
Interventions
Tenofovir Disoproxil Fumarate/Emtricitabine (TDF/FTC)
Drug
Lead sponsor
Eastern Virginia Medical School
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 29, 2024 · Synced Sep 15, 2026, 10:38 AM EDT
Withdrawn Phase 2 Interventional Accepts healthy volunteers

Combined Injectable Treatment for HIV and OUD

NCT05991622
View directory record Official record
Conditions
Human Immunodeficiency Virus, Opioid Use Disorder
Interventions
Combined LAI Treatment: Cabenuva and Sublocade
Drug
Lead sponsor
Rhode Island Hospital
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Sep 15, 2026, 10:38 AM EDT
Completed No phase listed Observational

A Medication Adherence Intervention for HIV Infected Veterans

NCT00013065
View directory record Official record
Conditions
HIV Infection
Interventions
Not listed
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 65 Years
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2003
U.S. locations
4
States / cities
Tucson, Arizona • Palo Alto, California • San Diego, California + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 6, 2015 · Synced Sep 15, 2026, 10:38 AM EDT