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ClinicalTrials.gov public records Last synced Jun 11, 2026, 12:21 AM EDT

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Showing 1–18 of 18 matching trials from the live ClinicalTrials.gov search.
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Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

A Multilevel, Multiphase Optimization Strategy for PrEP (MOST:PrEP)

NCT06334341
Conditions
HIV Seropositivity
Interventions
Computer-based simulation training for providers, Best Practice Alert, HIV Risk Assessment, PrEP Informational Video
Behavioral
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
1,380 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Detroit, Michigan
Conditions
HIV/AIDS
Interventions
Know@Home, Self-test Kit
Behavioral · Other
Lead sponsor
Emory University
Other
Eligibility
18 Years and older · Male only
Enrollment
2,195 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Atlanta, Georgia
Conditions
HIV Pre-exposure Prophylaxis, HIV Prevention and Care, Mobile Health Technology (mHealth), Adherence, Doxycycline STI PEP
Interventions
MyPrEP Plus Package, Standard of Care (SOC)
Device · Behavioral
Lead sponsor
Public Health Foundation Enterprises, Inc.
Other
Eligibility
18 Years and older · Male only
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
San Francisco, California
Conditions
Human Immunodeficiency Virus (HIV), HIV Pre-Exposure Prophylaxis
Interventions
MK-8527, FTC/TDF, Placebo to MK-8527, Placebo to FTC/TDF
Drug
Lead sponsor
Merck Sharp & Dohme LLC
Industry
Eligibility
16 Years and older
Enrollment
4,390 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
23
States / cities
Birmingham, Alabama • Mobile, Alabama • Los Angeles, California + 20 more
Conditions
HIV-infection/AIDS
Interventions
Cultural adaptation of a patient-provider communication tool
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older · Female only
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Birmingham, Alabama
Recruiting Not applicable Interventional Accepts healthy volunteers

California MEPS Hub

NCT07433985
Conditions
HIV Prevention, Sexually Transmitted Infections (STI), Preexposure Prophylaxis (PrEP), Incarceration, Hepatitis C Virus (HCV), Substance Use Disorder (SUD)
Interventions
Mobile Enhanced Prevention Support (MEPS), Control
Behavioral · Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 59 Years · Male only
Enrollment
318 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
3
States / cities
Oakland, California • Riverside, California
Withdrawn Not applicable Interventional Accepts healthy volunteers

Pre-Exposure Prophylaxis and Timed Intercourse for HIV-Discordant Couples

NCT02572505
Conditions
HIV, Infertility
Interventions
Truvada
Drug
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 40 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Columbia, Missouri
Conditions
HIV Prevention Program
Interventions
PrEP Awareness and Uptake Educational Program
Behavioral
Lead sponsor
Morehouse School of Medicine
Other
Eligibility
18 Years to 26 Years
Enrollment
123 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Atlanta, Georgia
Conditions
HIV Preexposure Prophylaxis
Interventions
ISL, FTC/TDF, FTC/TAF, Placebo to ISL, Placebo to FTC/TDF, Placebo to FTC/TAF
Drug
Lead sponsor
Merck Sharp & Dohme LLC
Industry
Eligibility
16 Years and older · Male only
Enrollment
494 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
15
States / cities
Birmingham, Alabama • Los Angeles, California • San Francisco, California + 11 more
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Client-Centered Care Coordination for Black Men Who Have Sex With Men

NCT06056544
Conditions
HIV Prevention, HIV Pre-exposure Prophylaxis
Interventions
Client Centered Care Coordination
Behavioral
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older · Male only
Enrollment
350 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Conditions
HIV
Interventions
maraviroc
Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years and older · Female only
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Atlanta, Georgia
Completed No phase listed Observational Accepts healthy volunteers

Sustainable Healthcenter Implementation PrEP Pilot Study

NCT02074891
Conditions
HIV Chemoprophylaxis, HIV Preexposure Prophylaxis
Interventions
coformulated TDF/FTC
Drug
Lead sponsor
Centers for Disease Control and Prevention
Federal
Eligibility
18 Years and older
Enrollment
1,420 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
5
States / cities
Washington D.C., District of Columbia • Chicago, Illinois • Jackson, Mississippi + 1 more
Recruiting Not applicable Interventional Accepts healthy volunteers

The Collaborative Care PrTNER Study

NCT06585631
Conditions
HIV, Substance Use Disorders, Substance Use, AIDS
Interventions
CC PrTNER
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
15 Years to 29 Years · Male only
Enrollment
275 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
2
States / cities
Baltimore, Maryland • Philadelphia, Pennsylvania
Conditions
HIV Infections, Opioid Use, Trauma, Psychological
Interventions
Not listed
Lead sponsor
Alexis Roth
Other
Eligibility
18 Years and older · Female only
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Clinical Decision Support for PrEP

NCT05245201
Conditions
HIV Infections, Preexposure Prophylaxis (PrEP)
Interventions
Standard of care, Clinical decision support for PrEP
Other
Lead sponsor
Harvard Pilgrim Health Care
Other
Eligibility
15 Years and older
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
3
States / cities
Los Angeles, California • Ahoskie, North Carolina • Gastonia, North Carolina
Conditions
Preexposure Prophylaxis, HIV Infections
Interventions
GYN Residency Training, Social Media Campaign
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 99 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
New Orleans, Louisiana
Conditions
HIV Infections, Opioid Use, Trauma, Psychological
Interventions
Expressive Writing, Contingency Management
Behavioral
Lead sponsor
Drexel University
Other
Eligibility
18 Years and older · Female only
Enrollment
219 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Terminated Phase 3 Interventional Accepts healthy volunteers Results available

Oral ISL QM as PrEP in Cisgender Women at High Risk for HIV-1 Infection (MK-8591-022)

NCT04644029
Conditions
HIV-I, Human Immunodeficiency Virus Type 1, Prophylaxis
Interventions
Islatravir, Placebo to FTC/TDF, FTC/TDF, Placebo to ISL
Drug
Lead sponsor
Merck Sharp & Dohme LLC
Industry
Eligibility
16 Years to 45 Years · Female only
Enrollment
730 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
13
States / cities
Birmingham, Alabama • Washington D.C., District of Columbia • Miami, Florida + 10 more