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Conditions: HIV, Opiate Dependence
Interventions: Abstinence-reinforcing contingency management intervention, Performance Feedback intervention; Behavioral
Lead sponsor: Albert Einstein College of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 242 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2017
U.S. locations: 3
States / cities: The Bronx, New York

Conditions: HIV Risk Behavior
Interventions: HIV Risk Behavior Intervention; Behavioral
Lead sponsor: Rhode Island Hospital; Other
Eligibility: 18 Years and older · Female only
Enrollment: 98 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2010
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: HIV Infections
Interventions: Cognitive behavioral intervention, Standard counseling; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older · Male only
Enrollment: 488 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2011
U.S. locations: 2
States / cities: San Francisco, California

Conditions: Risk Behavior, Medication Adherence, HIV
Interventions: 3H+ (Holistic Health for HIV), HHRP+ (Holistic Health Recovery Program); Behavioral
Lead sponsor: University of Connecticut; Other
Eligibility: 18 Years and older
Enrollment: 106 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2018
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Stimulant Abuse, HIV Prevention, Substance Abuse
Interventions: IMPACT, Standard of Care; Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years and older · Male only
Enrollment: 205 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2024
U.S. locations: 2
States / cities: Miami, Florida • Boston, Massachusetts

Conditions: Hiv, Adolescent Behavior, Sex, Safe
Interventions: Queer Sex Ed, Keep It Up, Keep It Up-Control, Young Men's Health Project; Behavioral
Lead sponsor: Northwestern University; Other
Eligibility: 13 Years to 18 Years · Male only
Enrollment: 1,306 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Opioid Use Disorder, Infectious Disease, Risk Reduction Behavior, Substance Use, Substance Abuse, Stimulant Use Disorder
Interventions: Patient Navigator, Mobile Health Unit; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 601 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 3
States / cities: New Haven, Connecticut • Dallas, Texas • Fort Worth, Texas

Conditions: Sex, Substance Use, HIV
Interventions: HIV prevention intervention randomized control trial; Behavioral
Lead sponsor: Hunter College of City University of New York; Other
Eligibility: 18 Years to 29 Years · Male only
Enrollment: 317 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2011
U.S. locations: 1
States / cities: New York, New York

Conditions: Directly Observed Therapy, HIV Infections
Interventions: Invirase, Norvir; Drug
Lead sponsor: Saint Michael's Medical Center; Other
Eligibility: 18 Years and older · Male only
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2006
U.S. locations: 1
States / cities: Newark, New Jersey

Conditions: Sexual Risk Behavior for HIV-infection, Reproductive Health
Interventions: PrEP Decision Aid, Generic Information; Device · Other
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: HIV Infections
Interventions: Delayed ART, Continuous ART; Drug
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 13 Years and older
Enrollment: 883 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2008
U.S. locations: 58
States / cities: Beverly Hills, California • Fresno, California • Mill Valley, California + 24 more

Conditions: HIV/AIDS
Interventions: LINK2 Youth Services Navigation Intervention; Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 16 Years to 25 Years · Male only
Enrollment: 106 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: HIV Infections, Substance Use
Interventions: Safer Sex Skills Building (SSB); Behavioral
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 380 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2012
U.S. locations: 2
States / cities: Richmond, Virginia

Conditions: HIV Infection
Interventions: Healthy Choices - Motivational Enhancement Intervention, Standard care; Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 16 Years to 24 Years
Enrollment: 225 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2008
U.S. locations: 6
States / cities: Los Angeles, California • Fort Lauderdale, Florida • Baltimore, Maryland + 2 more

Conditions: Adherence, Medication, Risk Behavior, Pre-Exposure Prophylaxis, HIV Prevention
Interventions: Emtricitabine / Tenofovir Disoproxil Oral Tablet, DOT Diary mobile app; Drug · Other
Lead sponsor: Public Health Foundation Enterprises, Inc.; Other
Eligibility: 18 Years to 35 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 2
States / cities: San Francisco, California • Atlanta, Georgia

Conditions: Alcohol Use Disorder, Risk Behavior, Health, Dysbiosis, HIV Infections
Interventions: Screening, Brief Intervention, Referral to Treatment (SBIRT); Behavioral
Lead sponsor: Shirish S Barve; Other
Eligibility: 18 Years to 85 Years
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Louisville, Kentucky

Conditions: HIV Infections, Sexually Transmitted Infections
Interventions: Healthy Love Workshop, HIV/AIDS 101 Workshop; Behavioral
Lead sponsor: Centers for Disease Control and Prevention; Federal
Eligibility: 18 Years and older · Female only
Enrollment: 313 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2008
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Cocaine-Related Disorders, Heroin Dependence, Opioid-Related Disorders, Substance Abuse, Intravenous
Interventions: employment-based reinforcement; Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 67 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2010
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: HIV Medication Adherence, Methamphetamine Use, Sexual Risk, Poly-substance Use, HIV Infections
Interventions: Motivational Interviewing + Cognitive Behavioral Skills Training, Education Attention Control; Behavioral
Lead sponsor: Hunter College of City University of New York; Other
Eligibility: 18 Years and older · Male only
Enrollment: 210 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2012
U.S. locations: 1
States / cities: New York, New York

Conditions: Substance Use Disorders, HIV Infections
Interventions: Virtual Reality Tool; Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 15 Years to 30 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Risk Reduction
Interventions: Information-motivation-behavior skills and cognitive processing therapy, Pre and Post HIV-Test Counseling; Behavioral
Lead sponsor: Fenway Community Health; Other
Eligibility: 18 Years and older · Male only
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 2
States / cities: Boston, Massachusetts

Conditions: HIV, Depression, Posttraumatic Stress Disorder
Interventions: Enhanced Sexual Health Intervention for Men (ES-HIM), Health Promotion (HP) Comparison Arm; Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years and older · Male only
Enrollment: 118 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2011
U.S. locations: 4
States / cities: Inglewood, California • Los Angeles, California

Conditions: HIV Infections, Domestic Violence, Sexually Transmitted Diseases
Interventions: Motivational interviewing to reduce risk for HIV and DV; Behavioral
Lead sponsor: Multnomah County Health Department; Government
Eligibility: 18 Years and older · Female only
Enrollment: 530 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2000 – 2005
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: HIV Infections, Peripheral Nervous System Disease
Interventions: Not listed
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 13 Years and older
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2001 – 2004
U.S. locations: 18
States / cities: Birmingham, Alabama • Los Angeles, California • Denver, Colorado + 11 more

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Project FIRST - Financial Incentives to Reduce Substance Use and Improve Treatment

Reducing HIV Risk Among Pregnant Women in Drug Treatment

Specialized Cognitive-Behavioral Counseling Intervention to Reduce HIV Transmission Risk Behavior in HIV-Infected Men

Secondary HIV Prevention and Adherence Among HIV-infected Drug Users

Integrated BA and HIV RR Counseling for MSM With Stimulant Abuse

A Pragmatic Trial of An Adaptive eHealth HIV Prevention Program for Diverse Adolescent MSM

Addressing Risk Through Community Treatment for Infectious Disease and Opioid Use Disorder Now (ACTION) Among Justice-involved Populations

Risk Reduction Intervention for Vulnerable Young Adult Males

Directly Observed Therapy in High Risk Populations in Newark, NJ

Integrating PrEP Decision Making Into Counseling in Sexual and Reproductive Health Clinics

Effects of Two Anti-HIV Drug Regimens on HIV Transmission Risk Behavior Among SMART Study Participants

Youth Services Navigation Intervention for HIV+ Youth Being Released From or At-risk for Incarceration

Reducing HIV: Safer Sex Skill Building in Pregnant Drug Abusing Women

Healthy Choices to Promote Health and Reduce Risk in HIV-Infected Youth

DOT Diary Mobile App for Pre-Exposure Prophylaxis Adherence in Young Men

Alcohol Misuse, Gut Microbial Dysbiosis and PrEP Care Continuum: Application and Efficacy of SBIRT Intervention

Evaluation of the Healthy Love Workshop, an HIV Prevention Intervention for African American Women

Employment-based Reinforcement of Naltrexone Ingestion and Abstinence

Intervention Targeting Medication Adherence and Methamphetamine Use in HIV Positive Men (ACE)

Development and Evaluation of a Virtual Reality Tool for At-Risk Trauma-Exposed Young People

HIV Prevention and Trauma Treatment in Men Who Have Sex With Men and Who Have a History of Sexual Abuse

An HIV Intervention for Black Men at Risk - The Enhanced Sexual Health Intervention for Men (ES-HIM)

Reducing HIV & Domestic Violence Risk in Women Offenders

Nerve Damage in Patients With HIV Infection Who Have Been Treated With Anti-HIV Drugs