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ClinicalTrials.gov public records Last synced Nov 10, 2026, 11:09 PM EST

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Showing 1321–1344 of 3,925 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: HTN Clear all
Completed No phase listed Observational Accepts healthy volunteers

Pulmonary Hypertension, Hypoxia and Sickle Cell Disease

NCT00495638
View directory record Official record
Conditions
Chuvash Polycythemia, Cerebrovascular Disease, Pulmonary Hypertension, Sickle Cell Anemia
Interventions
Not listed
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
3 Years to 20 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2014
U.S. locations
6
States / cities
Washington D.C., District of Columbia • Chicago, Illinois • Bethesda, Maryland + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 16, 2019 · Synced Nov 10, 2026, 11:09 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

Food as Medicine Project

NCT05926193
View directory record Official record
Conditions
Hypertension
Interventions
Tailor Food Bags
Dietary Supplement
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 22, 2023 · Synced Nov 10, 2026, 11:09 PM EST
Not listed No phase listed Observational

Assessment of Heparin Binding Protein for the Prediction of Severe Sepsis

NCT03113721
View directory record Official record
Conditions
Sepsis, Septic Shock, Sepsis With Acute Organ Dysfunction
Interventions
Not listed
Lead sponsor
Axis Shield Diagnostics Ltd
Industry
Eligibility
18 Years and older
Enrollment
571 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
5
States / cities
Philadelphia, Pennsylvania • York, Pennsylvania • Nashville, Tennessee + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 9, 2019 · Synced Nov 10, 2026, 11:09 PM EST
Completed Not applicable Interventional

OPTImizing Precision of Hypertension Care to Maximize Blood Pressure Control Pilot (OPTI-BP Pilot)

NCT02814552
View directory record Official record
Conditions
High Blood Pressure
Interventions
HTN PRA App, Blood Sample
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 65 Years
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
3
States / cities
Macclenny, Florida • Old Town, Florida • Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Oct 25, 2018 · Synced Nov 10, 2026, 11:09 PM EST
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Idiopathic Intracranial Hypertension Treatment Trial

NCT01003639
View directory record Official record
Conditions
Idiopathic Intracranial Hypertension
Interventions
Acetazolamide, Placebo, Formal weight loss counselling program
Drug · Behavioral
Lead sponsor
St. Luke's-Roosevelt Hospital Center
Other
Eligibility
18 Years to 60 Years
Enrollment
165 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
39
States / cities
Birmingham, Alabama • Los Angeles, California • Waterbury, Connecticut + 31 more
Source: ClinicalTrials.gov public record
Updated Dec 12, 2018 · Synced Nov 10, 2026, 11:09 PM EST
Active, not recruiting Phase 3 Interventional

Outcome Study Assessing a 75 Milligrams (mg) Dose of Macitentan in Patients With Pulmonary Arterial Hypertension

NCT04273945
View directory record Official record
Conditions
Pulmonary Arterial Hypertension
Interventions
Macitentan 10 mg, Macitentan 37.5 mg, Macitentan 75 mg, Placebo
Drug
Lead sponsor
Actelion
Industry
Eligibility
18 Years and older
Enrollment
935 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2029
U.S. locations
43
States / cities
Phoenix, Arizona • Scottsdale, Arizona • La Jolla, California + 35 more
Source: ClinicalTrials.gov public record
Updated Nov 3, 2026 · Synced Nov 10, 2026, 11:09 PM EST
Active, not recruiting Not applicable Interventional

DEDICATE: aDvancing carE Management aDoption In Community heAlTh cEnters

NCT06489002
View directory record Official record
Conditions
Social Determinants of Health, Primary Care, Diabetes Mellitus, Type 2, Hypertension, Non-medical Health-related Needs, Contextual Drivers of Health
Interventions
Implementation Support
Other
Lead sponsor
OCHIN, Inc.
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Nov 10, 2026, 11:09 PM EST
Completed Not applicable Interventional

High BP and Home Monitoring Experience (HoME) Study

NCT03650166
View directory record Official record
Conditions
High Blood Pressure
Interventions
MyBP, Personal BP monitor
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
55 Years and older
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 25, 2019 · Synced Nov 10, 2026, 11:09 PM EST
Completed Phase 1 Interventional Accepts healthy volunteers

Dose-Finding, Safety, Pharmacodynamic Effect Study of Sodium Nitrite Inhalation Solution in Normal, Healthy Volunteers

NCT00814645
View directory record Official record
Conditions
Pulmonary Arterial Hypertension
Interventions
Sodium Nitrite Inhalation Solution, Placebo and AIR001 Inhalation Solution (Expansion arm)
Drug
Lead sponsor
Aires Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 17, 2012 · Synced Nov 10, 2026, 11:09 PM EST
Terminated Phase 3 Interventional Results available

Pravastatin to Prevent Preeclampsia

NCT03944512
View directory record Official record
Conditions
Preeclampsia, Obstetric Labor Complications, Hypertension in Pregnancy
Interventions
Pravastatin, Placebo
Drug · Other
Lead sponsor
The George Washington University Biostatistics Center
Other
Eligibility
16 Years and older · Female only
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
12
States / cities
Birmingham, Alabama • Chicago, Illinois • New York, New York + 9 more
Source: ClinicalTrials.gov public record
Updated Dec 23, 2025 · Synced Nov 10, 2026, 11:09 PM EST
Completed Not applicable Interventional

Glaucoma Evaluation With the P200TE

NCT06305481
View directory record Official record
Conditions
Glaucoma
Interventions
P200TE
Device
Lead sponsor
Optos, PLC
Industry
Eligibility
22 Years and older
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
2
States / cities
Cajon, California • Bellevue, Washington
Source: ClinicalTrials.gov public record
Updated Feb 13, 2026 · Synced Nov 10, 2026, 11:09 PM EST
Completed No phase listed Observational Accepts healthy volunteers

Does Lowering Eye Pressure Affect the Results Obtained From Objective Visual Field Testing?

NCT00799994
View directory record Official record
Conditions
Glaucoma
Interventions
Not listed
Lead sponsor
Wills Eye
Other
Eligibility
Not listed
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 22, 2016 · Synced Nov 10, 2026, 11:09 PM EST
Completed No phase listed Observational

Comparative Effectiveness of Treatment Strategies for Primary Open-Angle Glaucoma

NCT01645319
View directory record Official record
Conditions
Open Angle Glaucoma
Interventions
Not listed
Lead sponsor
Agency for Healthcare Research and Quality (AHRQ)
Federal
Eligibility
18 Years and older
Enrollment
2,597 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 8, 2014 · Synced Nov 10, 2026, 11:09 PM EST
Completed Phase 2 Interventional Results available

Cooling Leg and Foot Ulcer Skin Post Healing to Prevent Ulcer Recurrence

NCT02626156
View directory record Official record
Conditions
Venous Hypertension Ulcers, Venous Stasis Ulcer, Venous Ulcer, Venous Insufficiency, Leg Ulcer, Foot Ulcer, Varicose Ulcer, Diabetic Foot
Interventions
Cooling gel pack, Cooling cotton pack
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
50 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
2
States / cities
Charleston, South Carolina • Spartanburg, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 30, 2021 · Synced Nov 10, 2026, 11:09 PM EST
Completed Not applicable Interventional Results available

The CHIPS Trial (Control of Hypertension In Pregnancy Study)

NCT01192412
View directory record Official record
Conditions
Gestational Hypertension
Interventions
Intervention is blood pressure management approach.
Procedure
Lead sponsor
University of British Columbia
Other
Eligibility
Female only
Enrollment
987 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
11
States / cities
New Haven, Connecticut • Louisville, Kentucky • Boston, Massachusetts + 7 more
Source: ClinicalTrials.gov public record
Updated Jan 11, 2017 · Synced Nov 10, 2026, 11:09 PM EST
Completed No phase listed Observational Accepts healthy volunteers

Aqueous Outflow Facility Changes With Posture

NCT00571012
View directory record Official record
Conditions
Healthy
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 45 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 26, 2009 · Synced Nov 10, 2026, 11:09 PM EST
Completed Not applicable Interventional

Peginterferon Alpha-2a Maintenance Therapy for Portal Hypertension in Patients With Hepatitis C

NCT00252642
View directory record Official record
Conditions
Hepatitis C, Cirrhosis, Fibrosis
Interventions
Peginterferon Alpha-2a
Drug
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 20, 2017 · Synced Nov 10, 2026, 11:09 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

Prospective Safety and Tolerability Assessment of a Cardiovascular Health Dietary Supplement

NCT02452749
View directory record Official record
Conditions
Hypertension
Interventions
Cardiovascular health dietary supplement
Dietary Supplement
Lead sponsor
National University of Natural Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 15, 2018 · Synced Nov 10, 2026, 11:09 PM EST
Not listed Not applicable Interventional

Effects of a Single Osteopathic Manipulative Treatment (OMT) on Intraocular Pressure (IOP) Reduction

NCT03590249
View directory record Official record
Conditions
Glaucoma
Interventions
Osteopathic Manipulative Treatment
Procedure
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Nov 13, 2023 · Synced Nov 10, 2026, 11:09 PM EST
Completed Not applicable Interventional

Cognitive/Cerebrovascular Consequences of HTN Treatment

NCT00151138
View directory record Official record
Conditions
Hypertension
Interventions
Atenolol (drug), Lisinopril (drug)
Drug
Lead sponsor
University of Pittsburgh
Other
Eligibility
35 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2007
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 17, 2007 · Synced Nov 10, 2026, 11:09 PM EST
Completed Not applicable Interventional

Study Title: Food Rx

NCT03937934
View directory record Official record
Conditions
Diabetes, High Blood Pressure, Obesity, Hypertension, Heart Diseases, Stroke, TIA, Osteoarthritis, Cancer
Interventions
Nutrition Education
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Mankato, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 9, 2020 · Synced Nov 10, 2026, 11:09 PM EST
Withdrawn Phase 4 Interventional

CLCNKA (Ka Renal Chloride Channel[ClC-Ka]) Polymorphism Effects on Hypertrophy Regression

NCT01275352
View directory record Official record
Conditions
Hypertension
Interventions
Eplerenone, placebo
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
40 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
2
States / cities
St Louis, Missouri • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 3, 2015 · Synced Nov 10, 2026, 11:09 PM EST
Completed Phase 2 Interventional

Uric Acid in Essential Hypertension in Children

NCT00288184
View directory record Official record
Conditions
Essential Hypertension
Interventions
Allopurinol, Placebo
Drug
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
12 Years to 18 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 14, 2017 · Synced Nov 10, 2026, 11:09 PM EST
Completed Phase 3 Interventional

The Health Outcomes Management and Evaluation (HOME) Study

NCT01228032
View directory record Official record
Conditions
Diabetes, Hyperlipidemia, Heart Disease, High Blood Pressure
Interventions
Care team
Other
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
447 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Marietta, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 26, 2016 · Synced Nov 10, 2026, 11:09 PM EST