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Showing 1–24 of 56 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Hazardous Behavior Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

Affirmative Psychotherapy for Sexual Minority Women's Mental and Behavioral Health

NCT05509166
View directory record Official record
Conditions
Heavy Drinking, Mental Health Issue
Interventions
LGBTQ-affirmative Cognitive Behavioral Therapy, LGBTQ-affirmative Treatment-As-Usual
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
274 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Sep 3, 2026, 9:24 AM EDT
Completed Not applicable Interventional

Personalized Feedback Intervention for Alcohol and Opioid Use Among Adults With Chronic Pain

NCT04592978
View directory record Official record
Conditions
Alcohol Drinking, Pain, Opioid Use, Feedback, Psychological
Interventions
Pain-Alcohol Personalized Feeback Intervention, Control Personalized Feedback Intervention
Behavioral
Lead sponsor
Syracuse University
Other
Eligibility
21 Years and older
Enrollment
206 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Oct 19, 2025 · Synced Sep 3, 2026, 9:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cannabis Impairment Detection Application (CIDA)

NCT04230460
View directory record Official record
Conditions
Driving Under the Influence, Marijuana Intoxication, Alcohol Intoxication
Interventions
Cannabis (THC) (Inhaled) Placebo, Cannabis (High% THC) (Inhaled), Cannabis (Very High% THC) (Inhaled), Alcohol (oral)
Drug
Lead sponsor
Advanced Brain Monitoring, Inc.
Industry
Eligibility
18 Years to 50 Years
Enrollment
124 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jul 11, 2021 · Synced Sep 3, 2026, 9:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Validation of Alcohol Level Identification Using DRIVESC

NCT07282405
View directory record Official record
Conditions
Driving Impaired
Interventions
DRIVESC, Alcohol
Diagnostic Test · Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 64 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Sep 3, 2026, 9:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Computerized Brief Alcohol Intervention (BI) for Binge Drinking HIV At-Risk and Infected Women

NCT01125371
View directory record Official record
Conditions
Alcohol; Harmful Use, Binge Drinking, Risk Behavior, HIV Infection
Interventions
Computerized brief alcohol intervention + IVR booster calls, Computerized brief alcohol intervention, Attention Control
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 90 Years · Female only
Enrollment
439 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 23, 2022 · Synced Sep 3, 2026, 9:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluating Perceived Fitness to Drive While Intoxicated

NCT05028413
View directory record Official record
Conditions
Alcohol Drinking, Alcohol Intoxication, Perception, Self, Drinking, Alcohol, Driving Under the Influence, Drinking Behavior
Interventions
Participants Shown their Breath Alcohol Content Measurement
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
21 Years to 39 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 30, 2024 · Synced Sep 3, 2026, 9:24 AM EDT
Withdrawn Not applicable Interventional

Pediatric Source Control for Hazardous Particulate Exposure in Aerosol Generating Procedures

NCT04577209
View directory record Official record
Conditions
Risk Reduction
Interventions
Disposable oxygen face tent
Device
Lead sponsor
Stanford University
Other
Eligibility
2 Years to 18 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated May 3, 2025 · Synced Sep 3, 2026, 9:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Developing a Team-Delivered Intervention for Smoking and Hazardous Drinking for Primary Care Veterans With Cardiovascular Diseases

NCT05275582
View directory record Official record
Conditions
Cigarette Use, Alcohol Use Above Recommended Limits, Cardiovascular Risk Factors (e.g., Hypertension), Cardiovascular Diseases
Interventions
CARE
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
2
States / cities
Buffalo, New York • Syracuse, New York
Source: ClinicalTrials.gov public record
Updated May 19, 2025 · Synced Sep 3, 2026, 9:24 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Strengths-based Linkage to Alcohol Care (SLAC) for Hazardous Drinkers in Primary Care

NCT05023317
View directory record Official record
Conditions
Alcohol-induced Disorders, Alcohol Drinking, Mental Health
Interventions
Strengths-based linkage to alcohol care, Usual care
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
2
States / cities
Little Rock, Arkansas • Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jan 12, 2026 · Synced Sep 3, 2026, 9:24 AM EDT
Active, not recruiting Not applicable Interventional

CBT vs. Supportive Texts for PTSD & Hazardous Drinking (Project Better Study 2)

NCT06648395
View directory record Official record
Conditions
Alcohol Use, Posttraumatic Stress Disorder
Interventions
CBT Text Messages, Supportive Messages
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
333 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 7, 2025 · Synced Sep 3, 2026, 9:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Computer-Delivered PFI for Anxiety Sensitivity/Alcohol Intervention for Hazardous Drinkers With Elevated Anxiety Sensitivity

NCT03917875
View directory record Official record
Conditions
Alcohol Drinking, Anxiety, Coping Behavior
Interventions
Personalized feedback intervention
Behavioral
Lead sponsor
University of Houston
Other
Eligibility
18 Years and older
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 24, 2020 · Synced Sep 3, 2026, 9:24 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

The Impact and Detection of Driving Impairments Associated With Acute Cannabis Smoking

NCT02849587
View directory record Official record
Conditions
Cannabis Intoxication
Interventions
Cannabis
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
21 Years to 55 Years
Enrollment
199 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jan 3, 2022 · Synced Sep 3, 2026, 9:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Smartphone-paired Breathalyzers and Loss- and Gain-framed Texts for Reducing Drinking and Driving

NCT03335735
View directory record Official record
Conditions
Alcohol Drinking, Alcohol Intoxication, Alcohol Impairment, Drive, Driving Impaired, Driving Under the Influence, Behavior, Drinking
Interventions
Loss-framed text message, Gain-Framed text message
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
21 Years to 39 Years
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 7, 2018 · Synced Sep 3, 2026, 9:24 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Parent Intervention to Reduce College Student Drinking and Consequences

NCT04247191
View directory record Official record
Conditions
Underage Drinking, Driving Under the Influence, Drinking, Teen, Drinking, College
Interventions
P-Chat+, PBI
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
18 Years to 19 Years
Enrollment
2,061 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Sep 3, 2026, 9:24 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Naltrexone for At-Risk and Problem Drinking in Smoking Cessation Treatment

NCT00938886
View directory record Official record
Conditions
Hazardous Drinking, Cigarette Smoking
Interventions
Naltrexone, Placebo
Drug
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2015
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 14, 2017 · Synced Sep 3, 2026, 9:24 AM EDT
Completed No phase listed Observational

Effect of Interferon Beta-1a (Avonex®) on Changes of Non-conventional MRI Measures in Patients With MS

NCT00463710
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Avonex® monotherapy (6.0 MIU administered i.m. each week)
Drug
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years to 65 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Dec 27, 2020 · Synced Sep 3, 2026, 9:24 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Ability of Partial Inverse Agonist, Iomazenil, to Block Ethanol Effects in Humans

NCT01590277
View directory record Official record
Conditions
Active Ethanol and Active Iomazenil, Active Ethanol and Placebo Iomazenil, Placebo Ethanol and Active Iomazenil, Placebo Ethanol and Placebo Iomazenil, Alcohol Effect, Driving Under the Influence, Alcohol Impairment
Interventions
Active Ethanol, Active Iomazenil, Placebo
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 35 Years · Male only
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2018
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 8, 2024 · Synced Sep 3, 2026, 9:24 AM EDT
Completed Not applicable Interventional

Study of an Emergency Department-based Intervention to Reduce Alcohol Misuse in Older Adults

NCT02236494
View directory record Official record
Conditions
Alcohol Abuse
Interventions
Brief Negotiated Interview, General Health Information
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
65 Years and older
Enrollment
222 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 11, 2017 · Synced Sep 3, 2026, 9:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Alcohol Impaired Driving in the Natural Environment

NCT03503396
View directory record Official record
Conditions
Driving Under the Influence
Interventions
BAC Driving Feedback/Warning, No Feedback
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
21 Years to 30 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated May 2, 2023 · Synced Sep 3, 2026, 9:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating Change in Drinking Identity as a Mechanism for Reducing Hazardous Drinking - Study 2

NCT03889873
View directory record Official record
Conditions
Drinking; Excess, Habit (Continual), Identity, Social
Interventions
Narrative Writing
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 25 Years
Enrollment
329 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 3, 2021 · Synced Sep 3, 2026, 9:24 AM EDT
Not listed Not applicable Interventional

Brief Personalized Feedback Intervention for Hazardous Drinking in an HIV Clinic

NCT03935945
View directory record Official record
Conditions
Alcohol Consumption
Interventions
Personalized Feedback Intervention
Behavioral
Lead sponsor
University of Houston
Other
Eligibility
18 Years to 50 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 1, 2019 · Synced Sep 3, 2026, 9:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Testing Brief Personalized Feedback Integrating Lab-based Alcohol Cue Information

NCT05873556
View directory record Official record
Conditions
Alcohol Consumption
Interventions
Lab-based Cue Reactivity Personalized Feedback Intervention (PFI)
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 24 Years
Enrollment
93 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 24, 2025 · Synced Sep 3, 2026, 9:24 AM EDT
Completed Not applicable Interventional

Behavior and Driving Safety Study II

NCT01270217
View directory record Official record
Conditions
Alcoholic Intoxication
Interventions
Brief motivational interview
Behavioral
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jul 10, 2017 · Synced Sep 3, 2026, 9:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Bystander Intervention for Hazardous Drinking

NCT06543342
View directory record Official record
Conditions
Hazardous Behavior, Alcohol Consequences
Interventions
Bystander Brief Motivational Intervention
Behavioral
Lead sponsor
Brown University
Other
Eligibility
17 Years and older
Enrollment
187 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 15, 2024 · Synced Sep 3, 2026, 9:24 AM EDT