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ClinicalTrials.gov public records Last synced Jul 21, 2026, 11:31 AM EDT

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Showing 1–24 of 452 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Head Injuries, Closed Clear all
Not listed No phase listed Observational Accepts healthy volunteers

Dynamic Vision Testing and Concussion Management Dream Team 65

NCT05326555
View directory record Official record
Conditions
Head Injury, Sport Injury, Concussion, Brain
Interventions
Dynamic Vision Testing (Bertec Vision Advantage System) and Balance Error Scoring System
Diagnostic Test
Lead sponsor
California State University, Northridge
Other
Eligibility
Not listed
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Northridge, California
Source: ClinicalTrials.gov public record
Updated Apr 12, 2022 · Synced Jul 21, 2026, 11:31 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Exercise Reset for Concussion in a Military Environment

NCT05498038
View directory record Official record
Conditions
Brain Concussion
Interventions
Aerobic Exercise
Behavioral
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years to 40 Years
Enrollment
168 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
2
States / cities
Fayetteville, North Carolina • Jacksonville, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Jul 21, 2026, 11:31 AM EDT
Terminated Phase 3 Interventional Results available

Treatment of Chronic Post-Traumatic Headache With OnabotulinumtoxinA

NCT02160535
View directory record Official record
Conditions
Chronic Post Traumatic Headache
Interventions
OnabotulinumtoxinA
Drug
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 60 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 22, 2018 · Synced Jul 21, 2026, 11:31 AM EDT
Recruiting Not applicable Interventional

Wearable Technology to Characterize and Treat mTBI Subtypes: Biofeedback-Based Precision Rehabilitation

NCT06381674
View directory record Official record
Conditions
Mild Traumatic Brain Injury, Concussion, Rehabilitation, Balance Impairment
Interventions
Vestibular therapy for mTBI augmented with audio and visual real-time biofeedback, Vestibular therapy for mTBI
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 60 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
3
States / cities
Portland, Oregon • San Antonio, Texas • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Oct 13, 2025 · Synced Jul 21, 2026, 11:31 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Cerebral Blood Flow Regulation and Concussions

NCT02754206
View directory record Official record
Conditions
Brain Concussion, Post-Concussion Syndrome
Interventions
Not listed
Lead sponsor
Southern Methodist University
Other
Eligibility
18 Years to 30 Years
Enrollment
79 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 13, 2021 · Synced Jul 21, 2026, 11:31 AM EDT
Active, not recruiting Not applicable Interventional

Brain Stimulation for Concussion

NCT05889117
View directory record Official record
Conditions
Transcranial Magnetic Stimulation, Magnetic Resonance Imaging, Neuropsychological Tests, Traumatic Brain Injury, Post-Concussion Syndrome
Interventions
Intermittent theta-burst treatment (iTBS) using MagPro Transcranial Magnetic Stimulator (manufacturer: Magventure)
Device
Lead sponsor
The Mind Research Network
Other
Eligibility
18 Years to 64 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Sep 29, 2025 · Synced Jul 21, 2026, 11:31 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Tissue Repository and Master Database for Concussion Biomarker and Risk Calculator Development

NCT02519998
View directory record Official record
Conditions
Brain Concussion
Interventions
Concussion
Other
Lead sponsor
Thomas Jefferson University
Other
Eligibility
10 Years and older
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 10, 2015 · Synced Jul 21, 2026, 11:31 AM EDT
Completed Not applicable Interventional Results available

Noninvasive Brain Stimulation on Memory in Individuals With Mild Cognitive Impairment and History of Brain Injury

NCT04504630
View directory record Official record
Conditions
Amnestic Mild Cognitive Impairment, Traumatic Brain Injury, Mild Traumatic Brain Injury
Interventions
High Definition Transcranial Direct Current Stimulation, Sham HD-tDCS
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
50 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 12, 2026 · Synced Jul 21, 2026, 11:31 AM EDT
Completed Not applicable Interventional Results available

Sub-Threshold Exercise Treatment for Adolescents With Sports Related Concussion

NCT02710123
View directory record Official record
Conditions
Brain Injury, Concussion
Interventions
Sub-Threshold exercise prescription, Structured stretching prescription
Other
Lead sponsor
University at Buffalo
Other
Eligibility
10 Years to 18 Years
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Jul 21, 2026, 11:31 AM EDT
Recruiting Not applicable Interventional

Evaluation of Cognitive Behavioral Therapy for Insomnia (CBT-I) in Individuals With Mild Traumatic Brain Injury (mTBI)

NCT07385105
View directory record Official record
Conditions
Sleep Architecture, Mild Traumatic Brain Injury, Sleep, Sleep and Circadian Problems
Interventions
Cognitive behavioral Therapy for insomnia (CBT-I)
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 60 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Jul 21, 2026, 11:31 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Is Y-Balance Test Predictive of Concussion

NCT05344703
View directory record Official record
Conditions
Concussion, Brain, Concussion; Eye
Interventions
Y Balance Plus Visual Perturbations, Y balance
Device · Diagnostic Test
Lead sponsor
Arkansas Colleges of Health Education
Other
Eligibility
11 Years to 19 Years
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
2
States / cities
Fort Smith, Arkansas
Source: ClinicalTrials.gov public record
Updated Apr 24, 2022 · Synced Jul 21, 2026, 11:31 AM EDT
Recruiting Not applicable Interventional

Clinical Trial Comparing the Efficacy of Two Teletherapy Programs at Improving Psychological Health in People With Brain Injury

NCT07436754
View directory record Official record
Conditions
Mild Traumatic Brain Injury, Alexithymia
Interventions
Program 1, Program 2
Behavioral
Lead sponsor
Hackensack Meridian Health
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
3
States / cities
Indianapolis, Indiana • Bethesda, Maryland • Edison, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Jul 21, 2026, 11:31 AM EDT
Recruiting Not applicable Interventional

Remotely Supervised tDCS+ for Complex Attention in mTBI (Cognetric)

NCT06413173
View directory record Official record
Conditions
Brain Concussion, Brain Trauma, Attention Concentration Difficulty, Brain Injuries, Brain Injuries, Traumatic, Neurocognitive Dysfunction, Attention Impaired, Memory Impairment, Mild Traumatic Brain Injury, Mild Cognitive Impairment, Post Concussive Symptoms
Interventions
Active tDCS and Cognitive Training Intervention, Sham tDCS and Cognitive Training Intervention
Combination Product
Lead sponsor
United States Naval Medical Center, San Diego
Federal
Eligibility
18 Years to 60 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
2
States / cities
San Diego, California • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 11, 2025 · Synced Jul 21, 2026, 11:31 AM EDT
Terminated Phase 3 Interventional Results available

Study to Evaluate the Safety, Tolerability, and Efficacy of Armodafinil as Treatment for Patients With Excessive Sleepiness Associated With Mild or Moderate Closed Traumatic Brain Injury

NCT00983437
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Armodafinil
Drug
Lead sponsor
Cephalon, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
61
States / cities
Birmingham, Alabama • Tucson, Arizona • Hot Springs, Arkansas + 49 more
Source: ClinicalTrials.gov public record
Updated Dec 16, 2021 · Synced Jul 21, 2026, 11:31 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Chronic Postconcussive Headache: A Placebo-Controlled Treatment Trial of Prazosin

NCT02266329
View directory record Official record
Conditions
Posttraumatic Headache, Combat Disorders, Post Concussion Syndrome, Headache, Mild Traumatic Brain Injury, Posttraumatic Migraine
Interventions
prazosin hydrochloride, placebo
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 29, 2026 · Synced Jul 21, 2026, 11:31 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Combined Effect of Chronic Cannabis Use and Subconcussive Head Impacts on Brain Health

NCT04641832
View directory record Official record
Conditions
Concussion, Mild
Interventions
Soccer heading
Other
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 26 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 1, 2023 · Synced Jul 21, 2026, 11:31 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Indirect Intracranial Pressure Measurement in Patients With Suspected or Documented Concussion

NCT02699359
View directory record Official record
Conditions
Brain Concussion, Brain Injuries
Interventions
HS-1000 recording
Device
Lead sponsor
HeadSense Medical
Industry
Eligibility
12 Years to 17 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Akron, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 29, 2019 · Synced Jul 21, 2026, 11:31 AM EDT
Recruiting No phase listed Observational

Screening Emotions in Adolescents at the Hospital for mTBI

NCT06370520
View directory record Official record
Conditions
Brain Injury Traumatic Mild, Brain Injuries, Brain Injuries, Acute, Head Injury With Intracranial Hemorrhage, Head Injury Trauma, Brain Injury Traumatic Focal With Loss of Consciousness, Skull Fractures, Diffuse Axonal Injury, Intracranial Hemorrhages, Head Injury
Interventions
Validated Questionnaires, Questionnaires, Clinician / Medical Record Variables
Behavioral · Other
Lead sponsor
University of California, Davis
Other
Eligibility
11 Years to 17 Years
Enrollment
2,592 participants
Timeline
2024 – 2028
U.S. locations
6
States / cities
Sacramento, California • Philadelphia, Pennsylvania • Providence, Rhode Island + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 25, 2025 · Synced Jul 21, 2026, 11:31 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Bright Light Therapy in Mild Traumatic Brain Injury

NCT01747811
View directory record Official record
Conditions
Concussion, Mild, Post-Concussion Symptoms, Sleep Problems
Interventions
wavelength-1 bright light, wavelength-2 bright light
Device
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 50 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated May 31, 2017 · Synced Jul 21, 2026, 11:31 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Craniosacral Therapy for Concussion Symptoms

NCT04820192
View directory record Official record
Conditions
Post-Concussion Syndrome
Interventions
Craniosacral Therapy
Other
Lead sponsor
Special Therapies, Inc.
Other
Eligibility
14 Years to 90 Years
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Waukesha, Wisconsin
Source: ClinicalTrials.gov public record
Updated Mar 28, 2021 · Synced Jul 21, 2026, 11:31 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Screening Brain MRI in High School Football: Does the Guardian Cap Reduce the Risk of Traumatic Brain Injury

NCT02757053
View directory record Official record
Conditions
Brain Concussion, Brain Injuries, Diffuse Axonal Injury, Athletic Injuries, Injury, Brain, Traumatic
Interventions
Guardian Cap
Device
Lead sponsor
Mosaic Life Care
Other
Eligibility
12 Years to 20 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Saint Joseph, Missouri
Source: ClinicalTrials.gov public record
Updated May 13, 2018 · Synced Jul 21, 2026, 11:31 AM EDT
Completed Not applicable Interventional

Neuraceq™ PET for Detection of Brain Changes in Young Athletes Post-concussion

NCT05270083
View directory record Official record
Conditions
Concussion, Brain
Interventions
NeuraCeq PET imaging with intravenous (IV) dose of 300MBq of Neuraceq™ ([F-18]Florbetaben)
Diagnostic Test
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years to 40 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Feb 27, 2024 · Synced Jul 21, 2026, 11:31 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Unblinded Data Collection Study of Concussion Using BrainPulse

NCT02992795
View directory record Official record
Conditions
Concussion, Intermediate
Interventions
BrainPulse
Device
Lead sponsor
Jan Medical, Inc.
Industry
Eligibility
18 Years to 28 Years
Enrollment
353 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Laramie, Wyoming
Source: ClinicalTrials.gov public record
Updated Sep 19, 2018 · Synced Jul 21, 2026, 11:31 AM EDT
Active, not recruiting Phase 2 Interventional

BCAAs in Concussion 2.0

NCT06829498
View directory record Official record
Conditions
Concussion, Brain, Concussion, Mild, Concussion
Interventions
BCAA, Placebo
Drug · Other
Lead sponsor
Akiva Cohen
Other
Eligibility
11 Years to 23 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Jul 21, 2026, 11:31 AM EDT