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Showing 1–24 of 1,577 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Head Injury Trauma Clear all
Terminated Not applicable Interventional

Reduction of Concussion Symptoms Through the Use of Osteopathic Manipulative Therapy

NCT04063618
View directory record Official record
Conditions
Concussion, Brain
Interventions
Osteopathic Manipulative Therapy, Standard of Care Concussion Treatment
Procedure
Lead sponsor
Matthew T. Mcelroy, DO
Other
Eligibility
Up to 24 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 30, 2023 · Synced Sep 12, 2026, 2:58 PM EDT
Completed Phase 2Phase 3 Interventional

RECONsolidation of Traumatic Memories to ResOLve Post Traumatic Stress Disorder (RECONTROLPTSD)

NCT03827057
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Traumatic Brain Injury
Interventions
Reconsolidation of Traumatic Memories (RTM), Prolonged Exposure (PE)
Behavioral
Lead sponsor
Uniformed Services University of the Health Sciences
Federal
Eligibility
18 Years and older
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 14, 2025 · Synced Sep 12, 2026, 2:58 PM EDT
Recruiting Phase 1Phase 2 Interventional

A Study to Assess the Safety and Efficacy of IPN10200 in Adult Participants With Upper Limb Spasticity.

NCT04752774
View directory record Official record
Conditions
Spasticity
Interventions
Corabotase, Placebo, Dysport
Biological · Drug
Lead sponsor
Ipsen
Industry
Eligibility
18 Years to 70 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2029
U.S. locations
5
States / cities
Downey, California • Overland Park, Kansas • Farmington Hills, Michigan + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Sep 12, 2026, 2:58 PM EDT
Active, not recruiting No phase listed Observational

Utilizing Electronic Clinical Decision Support to Enhance mTBI Care at the Primary Care Point of Entry

NCT06693778
View directory record Official record
Conditions
Brain Concussion, Mild Traumatic Brain Injury
Interventions
electronic Clinical Decision Support tool for risk stratification of pediatric patients with mTBI
Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
5 Years to 18 Years
Enrollment
3,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Sep 12, 2026, 2:58 PM EDT
Active, not recruiting Not applicable Interventional

Impact of Intensive Computerized Cognitive Training

NCT06130735
View directory record Official record
Conditions
Acquired Brain Injury, Mild Cognitive Impairment, Mild Neurocognitive Disorder
Interventions
Cognitive Computerized Training
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
25 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Sep 12, 2026, 2:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Neuroplasticity in TBI and Schizophrenia

NCT03995368
View directory record Official record
Conditions
Schizophrenia, Traumatic Brain Injury
Interventions
Electroencephalography
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
25 Years to 55 Years
Enrollment
93 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
West Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 12, 2026, 2:58 PM EDT
Completed Not applicable Interventional Results available

Remotely Supervised tDCS for Persistent Post-traumatic Headache

NCT04012853
View directory record Official record
Conditions
Persistent Post Traumatic Headache, Mild Traumatic Brain Injury
Interventions
transcranial direct current stimulation
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
20 Years to 60 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 13, 2023 · Synced Sep 12, 2026, 2:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mind-Body Skills Groups for the Treatment of War Zone Stress in Military and Veteran Populations

NCT01093053
View directory record Official record
Conditions
Stress Disorders, Post Traumatic, Brain Injuries, Depressive Disorder, Anxiety Disorders, Anger
Interventions
Mind-Body Skills Groups, Standard Treatment
Behavioral · Other
Lead sponsor
The Center for Mind-Body Medicine
Other
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Jan 28, 2014 · Synced Sep 12, 2026, 2:58 PM EDT
Completed Phase 1 Interventional

Spreading Depolarization and Ketamine Suppression

NCT02501941
View directory record Official record
Conditions
Cortical Spreading Depolarization, Cortical Spreading Depression, Subarachoid Hemorrhage, Traumatic Brain Injury
Interventions
ketamine
Drug
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years to 90 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Jan 10, 2024 · Synced Sep 12, 2026, 2:58 PM EDT
Terminated Phase 4 Interventional

A Study to Evaluate the Efficacy of Somatropin in Adults With Growth Hormone Deficiency Caused by Trauma and/or Head Injury

NCT00638053
View directory record Official record
Conditions
Brain Injuries, Growth Hormone Deficiency Dwarfism
Interventions
somatropin
Genetic
Lead sponsor
Pfizer
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2003
U.S. locations
4
States / cities
Pittsburgh, Pennsylvania • El Paso, Texas • Salt Lake City, Utah + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 31, 2008 · Synced Sep 12, 2026, 2:58 PM EDT
Active, not recruiting Not applicable Interventional

Expanding Delivery of an Evidence-based Weight-loss Intervention to Enhance Access and Reach Underserved Groups After TBI

NCT05699772
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Telehealth-delivered Group Lifestyle Balance for people with TBI (tGLB-TBI), Brain Health Group (BHG)
Behavioral
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years to 80 Years
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 5, 2025 · Synced Sep 12, 2026, 2:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Blended Reality Immersion for Geriatric Head Trauma: The BRIGHT Study

NCT06074328
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Virtual Reality Neurocognitive Exercises administered through an Oculus Headset
Device
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
65 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 18, 2025 · Synced Sep 12, 2026, 2:58 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

An Exploration of the Relationship Between Chronic Pain and Suicide Attempt Among Veterans

NCT01502436
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Traumatic Brain Injury, Suicide Attempt
Interventions
Not listed
Lead sponsor
VA Eastern Colorado Health Care System
Federal
Eligibility
18 Years to 89 Years
Enrollment
230 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2014
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 27, 2023 · Synced Sep 12, 2026, 2:58 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Addressing Attitudes to Improve Use of Protective Headwear in Older Adults

NCT01582464
View directory record Official record
Conditions
Injury of Unknown Intent Due to Fall From Height, Traumatic Brain Injury
Interventions
Social Marketing for protective headgear
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
65 Years and older
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Multiple, California
Source: ClinicalTrials.gov public record
Updated May 8, 2016 · Synced Sep 12, 2026, 2:58 PM EDT
Completed Not applicable Interventional

Strategy Based Technique to Enhance Memory (STEM) for Improving New Learning and Memory (NLM) in Moderate to Severe TBI

NCT04054596
View directory record Official record
Conditions
Traumatic Brain Injury, Cognitive Impairment
Interventions
SME
Behavioral
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
1
States / cities
East Hanover, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 19, 2025 · Synced Sep 12, 2026, 2:58 PM EDT
Completed Not applicable Interventional

Pilot Trial for Adults With Acquired Brain Injury

NCT05793827
View directory record Official record
Conditions
Acquired Brain Injury, Traumatic Brain Injury, Stroke
Interventions
Adapted Hatha Yoga, Low-Impact Exercise
Behavioral
Lead sponsor
Colorado State University
Other
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 25, 2024 · Synced Sep 12, 2026, 2:58 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

EEG Diagnostic for Repetitive Sub-concussive Head Impacts

NCT05562544
View directory record Official record
Conditions
Concussion
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 38 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Jun 20, 2024 · Synced Sep 12, 2026, 2:58 PM EDT
Not listed No phase listed Observational

Optimization of Human Cortical Stimulation

NCT01198964
View directory record Official record
Conditions
Epilepsy, Brain Injury
Interventions
Low-level cortical stimulation
Procedure
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2023
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 26, 2021 · Synced Sep 12, 2026, 2:58 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

PatientSpot Formerly Known as ArthritisPower

NCT03840928
View directory record Official record
Conditions
Rheumatoid Arthritis, Ankylosing Spondylitis, Fibromyalgia, Gout, Crohn Disease, Juvenile Idiopathic Arthritis, Lupus Erythematosus, Myositis, Osteoarthritis, Osteoporosis, Psoriasis, Psoriatic Arthritis, Scleroderma, Dermatomyositis, Inflammatory Bowel Diseases, Polymyositis, Axial Spondyloarthritis, Diffuse Idiopathic Skeletal Hyperostosis, Polymyalgia Rheumatica, Giant Cell Arteritis, Temporal Arteritis, Wegener, Relapsing Polychondritis, Undifferentiated Connective Tissue Disease, Spinal Cord Injuries, Alzheimer Disease, Amyotrophic Lateral Sclerosis, Ataxia, Bell Palsy, Brain Tumor, Cerebral Aneurysm, Epilepsy, Guillain-Barre Syndrome, Headache, Head Injury, Hydrocephalus, Lumbar Disc Disease, Meningitis, Multiple Sclerosis, Muscular Dystrophy, Neurocutaneous Syndromes, Parkinson Disease, Stroke, Cluster Headache, Tension-Type Headache, Chronic Obstructive Pulmonary Disease, Asthma, Lung Cancer, Cystic Fibrosis, Sleep Apnea, Eczema, Alopecia, Chronic Inflammation, Unstable Angina, Heart Attack, Heart Failure, Arrythmia, Valve Heart Disease, High Blood Pressure, Congenital Heart Disease, Peripheral Arterial Disease, Diabetes, Chronic Liver Disease, Obesity
Interventions
Not listed
Lead sponsor
Global Healthy Living Foundation
Other
Eligibility
19 Years and older
Enrollment
40,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2025
U.S. locations
1
States / cities
Upper Nyack, New York
Source: ClinicalTrials.gov public record
Updated Dec 12, 2023 · Synced Sep 12, 2026, 2:58 PM EDT
Completed Not applicable Interventional

Improving Executive Functioning After Traumatic Brain Injury (TBI): A Trial of the "Short Term Executive Plus" Program

NCT00627237
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Immediate Start, Waitlist
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 23, 2013 · Synced Sep 12, 2026, 2:58 PM EDT
Completed No phase listed Observational

Objective Brain Function Assessment of mTBI/Concussion in High School Athletes

NCT02661633
View directory record Official record
Conditions
Brain Injuries, Traumatic, Concussion, Brain, Concussion, Mild, Concussion, Intermediate, Concussion, Severe
Interventions
BrainScope Ahead 200iD, Advanced MRI Neuroimaging
Device
Lead sponsor
BrainScope Company, Inc.
Industry
Eligibility
13 Years to 19 Years
Enrollment
177 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
4
States / cities
Fayetteville, Arkansas • Bethesda, Maryland • East Lansing, Michigan + 1 more
Source: ClinicalTrials.gov public record
Updated May 22, 2019 · Synced Sep 12, 2026, 2:58 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Traumatic Brain Injury Feasibility Study (EPIC-011)

NCT02471625
View directory record Official record
Conditions
Traumatic Brain Injury, Controls
Interventions
ClearView Scanning
Device
Lead sponsor
Epic Research & Diagnostics, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2015
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Nov 19, 2015 · Synced Sep 12, 2026, 2:58 PM EDT
Completed Phase 2 Interventional Results available

Study of Allogeneic Umbilical Cord Blood Infusion for Adults With Ischemic Stroke

NCT03004976
View directory record Official record
Conditions
Stroke, Stroke, Acute, Brain Injury, Acute
Interventions
Umbilical Cord Blood, Placebo
Biological · Other
Lead sponsor
Joanne Kurtzberg, MD
Other
Eligibility
18 Years to 90 Years
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
6
States / cities
Aurora, Colorado • Gainesville, Florida • Atlanta, Georgia + 3 more
Source: ClinicalTrials.gov public record
Updated Dec 5, 2022 · Synced Sep 12, 2026, 2:58 PM EDT
Terminated Not applicable Interventional

A Prospective, Randomized Trial of Early Versus Late Tracheostomy in Trauma Patients With Severe Brain Injury

NCT00292097
View directory record Official record
Conditions
Respiratory Failure, Traumatic Brain Injury
Interventions
Early tracheostomy, Late tracheostomy
Procedure
Lead sponsor
Memorial Medical Center
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Johnstown, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 4, 2008 · Synced Sep 12, 2026, 2:58 PM EDT