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Showing 1–24 of 80 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Healing Surgical Wounds Clear all
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Distance Healing in Wound Healing

NCT00067717
View directory record Official record
Conditions
Breast Reconstruction Surgery
Interventions
Distance healing
Behavioral
Lead sponsor
California Pacific Medical Center Research Institute
Other
Eligibility
34 Years to 64 Years · Female only
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2008
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 19, 2014 · Synced Sep 23, 2026, 8:59 AM EDT
Enrolling by invitation Not applicable Interventional

Comparing the Impact of AMNIOEFFECT Application vs Standard of Care on Post-Operative Healing in Patients Who Have Undergone Thyroid and Parathyroid Surgery Via the Transcutaneous Approach

NCT07173621
View directory record Official record
Conditions
Thyroid; Wound, Parathyroid Diseases, Surgical Incision, Incision
Interventions
Amnioeffect
Other
Lead sponsor
Sarasota Memorial Health Care System
Other
Eligibility
18 Years and older
Enrollment
334 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Sarasota, Florida
Source: ClinicalTrials.gov public record
Updated Aug 2, 2026 · Synced Sep 23, 2026, 8:59 AM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Efficacy and Safety of 0.25% Timolol Gel in Healing Surgical Open Wounds

NCT03452072
View directory record Official record
Conditions
Wound of Skin, Wound Heal, Wound Open, Surgical Wound
Interventions
0.25% Timolol gel with paraffin gauze dressings, Vaseline dressing
Drug · Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
87 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Sep 23, 2026, 8:59 AM EDT
Not yet recruiting Phase 2 Interventional

Efficacy and Safety of Topical Timolol in Secondary Intention Surgical Wounds Healing

NCT07384767
View directory record Official record
Conditions
Mohs Micrographic Surgery, Excision Margin
Interventions
Timolol 0.5% Ophthalmic Solution, Hydrogel of placebo
Drug · Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Sep 23, 2026, 8:59 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Incisional Negative Pressure Wound Therapy in High Risk Patients Undergoing Panniculectomy: A Prospective Randomized Controlled Trial

NCT03010137
View directory record Official record
Conditions
Complications Wounds, Negative Pressure Wound Therapy, Wound Healing Delayed, Incisional, Panniculectomy, Incisional Negative Pressure Wound Therapy, Incisional Vac, Wound Vac, Obese, Renal Failure, Kidney Transplant; Complications, Wound Healing Complication
Interventions
Incisional Negative Pressure Wound Therapy, Standard Closure with Skin Glue, PICO (Smith&Nephew), Dermabond
Procedure · Device
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jun 8, 2020 · Synced Sep 23, 2026, 8:59 AM EDT
Enrolling by invitation Not applicable Interventional

Preoperative Silicone Ointment and Wound Healing

NCT05461157
View directory record Official record
Conditions
Wound Heal, Scar, Scar, Hypertrophic, Keloid, Keloid Scar Following Surgery, Surgical Incision
Interventions
Preoperative silicone ointment, Preoperative placebo ointment
Device · Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Sep 23, 2026, 8:59 AM EDT
Recruiting Phase 1 Interventional

Topical 0.5% Timolol Solution for Healing Lower Extremity Wounds

NCT06941467
View directory record Official record
Conditions
Wound Healing, Mohs Micrographic Surgery
Interventions
Timolol Maleate Solution, Standard of Care
Drug · Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 22, 2025 · Synced Sep 23, 2026, 8:59 AM EDT
Completed Not applicable Interventional Results available

The Effect of Natrox® Oxygen Wound Therapy on the Healing Rate of Chronic Diabetic Foot Ulcers

NCT03905863
View directory record Official record
Conditions
Diabetic Foot Ulcer, Surgical Wound
Interventions
Natrox® Oxygen Wound Therapy
Device
Lead sponsor
Inotec AMD Limited
Industry
Eligibility
18 Years and older
Enrollment
145 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
19
States / cities
Los Angeles, California • Miami, Florida • Miami Lakes, Florida + 15 more
Source: ClinicalTrials.gov public record
Updated Nov 21, 2021 · Synced Sep 23, 2026, 8:59 AM EDT
Recruiting Phase 3 Interventional

The Effect of Bacterial Decolonization Before Skin Cancer Surgery on Infection Rate of Lower Extremity Wounds Left Open to Heal

NCT07142408
View directory record Official record
Conditions
Surgical Wound Infection
Interventions
Chlorhexidine gluconate (4%), Mupirocin 2% Ointment
Drug
Lead sponsor
The Cooper Health System
Other
Eligibility
18 Years and older
Enrollment
848 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2030
U.S. locations
1
States / cities
Marlton, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 25, 2025 · Synced Sep 23, 2026, 8:59 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Wound Healing in Primary TKA

NCT06007599
View directory record Official record
Conditions
Total Knee Replacement, Wound Complication
Interventions
Skin closure using skin adhesive, Skin closure without skin adhesive
Procedure
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years and older
Enrollment
216 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 22, 2023 · Synced Sep 23, 2026, 8:59 AM EDT
Not listed No phase listed Observational

Long Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds

NCT03880188
View directory record Official record
Conditions
Wounds and Injuries, Wound Infection, Facial Bones Fracture, Soft Tissue Injuries, Skull Fractures, Surgical Wound, Surgical Wound Infection, Wound Healing, Disturbance of Wound Healing, Wound; Head, Multiple, Wound; Head, Scalp, Wound; Head, Wound Complication, Wound Dehiscence, Wound of Skin, Wound Open, Wounds, Penetrating, Wounds, Nonpenetrating, Wounds
Interventions
Not listed
Lead sponsor
Dufresne, Craig, MD, PC
Other
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Fairfax, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 15, 2022 · Synced Sep 23, 2026, 8:59 AM EDT
Recruiting Not applicable Interventional

Study of Miro3D Wound Matrix for Healing Wounds and Ulcers in Outpatient Care

NCT06939673
View directory record Official record
Conditions
Diabetic Foot Ulcers (DFUs), Venous Leg Ulcers (VLUs), Pressure Ulcers, Surgical Wound Dehiscence (SWD), Chronic Wounds, Undermined and Tunneling Wounds
Interventions
Acellular Porcine-Derived Wound Matrix
Device
Lead sponsor
Reprise Biomedical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
2
States / cities
Coconut Creek, Florida • Tamarac, Florida
Source: ClinicalTrials.gov public record
Updated Dec 23, 2025 · Synced Sep 23, 2026, 8:59 AM EDT
Recruiting Not applicable Interventional

Negative Pressure Wound Therapy in Healing Abdominal Incision in Obese Patients Undergoing Breast Reconstruction Surgery

NCT04003038
View directory record Official record
Conditions
Body Mass Index Greater Than or Equal to 30, Malignant Breast Neoplasm, Mammoplasty Patient, Obesity
Interventions
Negative Pressure Wound Therapy, Wound Care Management
Procedure
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Sep 23, 2026, 8:59 AM EDT
Not yet recruiting Phase 2 Interventional

The Effects of Timolol On Healing and Cosmesis of Mohs Scalp Wounds: An Open Label Trial

NCT07583862
View directory record Official record
Conditions
Surgical Wounds, Mohs Surgery
Interventions
Topical Timolol, Normal Saline
Drug
Lead sponsor
Geisinger Clinic
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 12, 2026 · Synced Sep 23, 2026, 8:59 AM EDT
Not yet recruiting Phase 1 Interventional

Impact of BPC-157 on Recovery Following Rotator Cuff Repair Surgery

NCT07803250
View directory record Official record
Conditions
Rotator Cuff Tear
Interventions
BPC-157, Sham (No Treatment)
Drug · Other
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Sep 23, 2026, 8:59 AM EDT
Completed Phase 2 Interventional

Evaluating rhPDGF-BB-Enhanced Wound Matrix for Head and Neck Reconstruction

NCT06634030
View directory record Official record
Conditions
Wound Healing, Surgical Wound
Interventions
RhPDGF-BB, Saline
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
22 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Sep 23, 2026, 8:59 AM EDT
Withdrawn Phase 2 Interventional

A Proof-of-Concept Study Investigating the Safety and Efficacy of ZT-031 on Hip Fracture Healing in Men and Postmenopausal Women

NCT00787358
View directory record Official record
Conditions
Hip Fracture
Interventions
ZT-031, placebo
Drug · Other
Lead sponsor
Zelos Therapeutics
Industry
Eligibility
30 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jun 3, 2009 · Synced Sep 23, 2026, 8:59 AM EDT
Not listed No phase listed Observational

Short Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds

NCT03872544
View directory record Official record
Conditions
Wound; Head, Multiple, Wound; Head, Scalp, Wound; Head, Wound Infection, Wound Complication, Wound Dehiscence, Wound of Skin, Wound Open, Wounds, Penetrating, Wounds, Nonpenetrating, Wounds and Injuries, Wounds, Disturbance of Wound Healing, Facial Bones Fracture, Soft Tissue Injuries, Skull Fractures, Surgical Wound, Surgical Wound Infection, Wound Healing
Interventions
Not listed
Lead sponsor
Dufresne, Craig, MD, PC
Other
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Fairfax, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 15, 2022 · Synced Sep 23, 2026, 8:59 AM EDT
Completed Not applicable Interventional Results available

A Study of a Novel Silicone Dressing to Minimize Scar Formation

NCT01399099
View directory record Official record
Conditions
Hypertrophic
Interventions
embrace device
Device
Lead sponsor
Neodyne Biosciences, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
13
States / cities
Atherton, California • Bakersfield, California • Danville, California + 10 more
Source: ClinicalTrials.gov public record
Updated Nov 18, 2024 · Synced Sep 23, 2026, 8:59 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Healing Ointment Usage Post-surgical Procedure

NCT05686928
View directory record Official record
Conditions
Surgical Wound
Interventions
Cetaphil Healing Ointment
Drug
Lead sponsor
Galderma R&D
Industry
Eligibility
18 Years to 85 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
2
States / cities
Dallas, Texas • Frisco, Texas
Source: ClinicalTrials.gov public record
Updated May 21, 2025 · Synced Sep 23, 2026, 8:59 AM EDT
Completed Not applicable Interventional

The Effects of Topical Calcium Glycerophosphate on Surgical Wound Healing and Residual Scarring

NCT01264588
View directory record Official record
Conditions
Wound Healing, Scarring
Interventions
Topical calcium glycerophosphate lotion
Other
Lead sponsor
AkPharma Inc.
Industry
Eligibility
45 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Egg Harbor, New Jersey
Source: ClinicalTrials.gov public record
Updated Dec 21, 2010 · Synced Sep 23, 2026, 8:59 AM EDT
Not yet recruiting No phase listed Observational

Surgical Critical Care Initiative (SC2i) Tissue and Data Acquisition Protocol (TDAP) in Burn Patients Improving the Robustness and Generalizability of Post-burn Sepsis Prediction With the Post-Burn Sepsis Digital Twin. Group 1

NCT07249762
View directory record Official record
Conditions
Sepsis, Burn Injury, Wound Healing, Critical Illness, Multiple Organ Dysfunction Syndrome
Interventions
Observational Cohort (No Intervention)
Other
Lead sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine
Other
Eligibility
18 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
3
States / cities
Tampa, Florida • Atlanta, Georgia • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Sep 23, 2026, 8:59 AM EDT
Completed Not applicable Interventional Results available

PICO Breast Reduction Clinical Study Looking at Incision Healing Complications

NCT01640366
View directory record Official record
Conditions
Delayed Healing
Interventions
PICO
Device
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
3
States / cities
Chicago, Illinois • The Bronx, New York • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 27, 2020 · Synced Sep 23, 2026, 8:59 AM EDT
Not listed No phase listed Observational

Negative Pressure Wound Therapy Registry

NCT02467998
View directory record Official record
Conditions
Diabetic Foot Ulcers, Venous Stasis Ulcer, Pressure Ulcer, Surgical Wound Dehiscence, Burns, Other Types of Chronic Non Healing Wounds
Interventions
NPWT
Device
Lead sponsor
U.S. Wound Registry
Other
Eligibility
Not listed
Enrollment
50,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2005
U.S. locations
1
States / cities
The Woodlands, Texas
Source: ClinicalTrials.gov public record
Updated Apr 30, 2018 · Synced Sep 23, 2026, 8:59 AM EDT