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Showing 1–24 of 252 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Health Related Quality of Life Clear all
Completed Not applicable Interventional

Improving Drug Use for Elderly Heart Failure Patients

NCT00388622
View directory record Official record
Conditions
Heart Failure
Interventions
Pharmacist intervention
Behavioral
Lead sponsor
University of North Carolina
Other
Eligibility
50 Years and older
Enrollment
314 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2004
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 16, 2006 · Synced Sep 20, 2026, 5:49 PM EDT
Completed Not applicable Interventional

Improving Exercise Capacity With Tailored Physical Activity in Lymphoma & Breast Cancer Patients Undergoing Tx

NCT03923504
View directory record Official record
Conditions
Hodgkin Lymphoma, Non-hodgkin Lymphoma, Lymphoma, Breast Cancer
Interventions
Physical Activity Intervention (PAI), Healthy Living Control
Other
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 85 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
2
States / cities
Richmond, Virginia • South Hill, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 6, 2023 · Synced Sep 20, 2026, 5:49 PM EDT
Recruiting Phase 2 Interventional

Long-Term Outcomes Following HBOT

NCT07732374
View directory record Official record
Conditions
Traumatic Brain Injury, Post-Concussive Symptoms, Post-Traumatic Stress Disorder
Interventions
Hyperbaric Oxygen Therapy (HBOT)
Drug
Lead sponsor
Summit Hyperbarics and Wellness
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boise, Idaho
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Sep 20, 2026, 5:49 PM EDT
Completed Not applicable Interventional Results available

Technology and Family Thriving Study

NCT05150990
View directory record Official record
Conditions
Alzheimer Disease, Dementia, Caregiver Burnout, Quality of Life, Mental Health Wellness 1, Loneliness, Family Relationship
Interventions
Virtual Reality, Video Chat
Behavioral
Lead sponsor
University of California, Santa Barbara
Other
Eligibility
18 Years and older
Enrollment
186 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
27
States / cities
Calabasas, California • Camarillo, California • Goleta, California + 16 more
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Sep 20, 2026, 5:49 PM EDT
Completed No phase listed Observational

Health-Related Symptom Questionnaires in Measuring Quality of Life in HIV-Infected Participants Treated or Monitored for Anal Lesions

NCT02418494
View directory record Official record
Conditions
High Grade Anal Canal Squamous Intraepithelial Neoplasia, HIV Infection
Interventions
Concept Elicitation, Comprehension Assessment
Other
Lead sponsor
AIDS Malignancy Consortium
Network
Eligibility
35 Years and older
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
6
States / cities
San Francisco, California • Chicago, Illinois • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 8, 2016 · Synced Sep 20, 2026, 5:49 PM EDT
Not listed Phase 4 Interventional

Comparison of Between ThinSeed™ and OncoSeed™ for Permanent Prostate Brachytherapy

NCT01379742
View directory record Official record
Conditions
Prostate Cancer
Interventions
RapidStrand seeds for use with 18g needle, ThinStrand
Device
Lead sponsor
Prostate Cancer Foundation of Chicago
Other
Eligibility
40 Years and older · Male only
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2010
U.S. locations
1
States / cities
Westmont, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 12, 2013 · Synced Sep 20, 2026, 5:49 PM EDT
Completed No phase listed Observational

Quality of Life in Patients Who Have Undergone Stem Cell Transplant

NCT00128960
View directory record Official record
Conditions
Long Term Psychological Affects on HSCT
Interventions
Not listed
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
18 Years and older
Enrollment
173 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Sep 20, 2026, 5:49 PM EDT
Completed Phase 4 Interventional Results available

A Study Evaluating the Efficacy and Impact on Health-related Quality of Life of Levocetirizine in Adults With Seasonal Allergic Rhinitis

NCT00653224
View directory record Official record
Conditions
Seasonal Allergic Rhinitis
Interventions
levocetirizine dihydrochloride, placebo
Drug
Lead sponsor
UCB Pharma
Industry
Eligibility
18 Years to 65 Years
Enrollment
580 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
38
States / cities
Tucson, Arizona • Los Angeles, California • Sacramento, California + 35 more
Source: ClinicalTrials.gov public record
Updated Aug 30, 2011 · Synced Sep 20, 2026, 5:49 PM EDT
Recruiting Phase 2 Interventional

Compare Adjuvant Monotherapy With Endocrine or Accelerated Partial Breast Irradiation After Lumpectomy

NCT05472792
View directory record Official record
Conditions
Breast Cancer, Quality of Life
Interventions
Accelerated Partial Breast Irradiation (APBI), tamoxifen, anastrozole, exemestane, letrozole, fulvestrant, toremifene
Radiation · Drug
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
65 Years and older · Female only
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2032
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated May 25, 2026 · Synced Sep 20, 2026, 5:49 PM EDT
Recruiting No phase listed Observational

Observational Study to Describe Health-Related Quality of Life and Measure Disease Burden Among Patients With Long QT Syndrome Types (LQTS) 2 and 3

NCT07075445
View directory record Official record
Conditions
Long QT Syndrome Type 3, Long QT Syndrome 2
Interventions
Not listed
Lead sponsor
Thryv Therapeutics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 16, 2025 · Synced Sep 20, 2026, 5:49 PM EDT
Completed Not applicable Interventional

Randomized Controlled Trial of Mind-Body Breathing Therapy (in Chronic Obstructive Pulmonary Disease) To Improve Palliation of Dyspnea and Health-Related Quality of Life

NCT00243282
View directory record Official record
Conditions
Pulmonary Disease, Chronic Obstructive
Interventions
Relaxation Response (instruction, pocket practice card prov), Mindfulness training using model developed from UMass
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
Not listed
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 20, 2009 · Synced Sep 20, 2026, 5:49 PM EDT
Completed Phase 4 Interventional Results available

A Study to Evaluate the Effect of Deucravacitinib on Quality of Life in Participants With Plaque Psoriasis in a Community Setting

NCT05701995
View directory record Official record
Conditions
Psoriasis
Interventions
Deucravacitinib, Placebo
Drug · Other
Lead sponsor
Bristol-Myers Squibb
Industry
Eligibility
18 Years and older
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
35
States / cities
Phoenix, Arizona • Scottsdale, Arizona • North Little Rock, Arkansas + 31 more
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Sep 20, 2026, 5:49 PM EDT
Completed Not applicable Interventional

Oncotool for Cancer Medications

NCT03952312
View directory record Official record
Conditions
Cancer, Cancer, Treatment-Related, Medication Adherence, Communication, Tyrosine Kinase Inhibitor
Interventions
Oncotool Intervention (symptom reporting + TKI education), Oncotool Control (health information)
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 25, 2023 · Synced Sep 20, 2026, 5:49 PM EDT
Terminated No phase listed Observational

Assessment of Health Related Quality of Life in Patients Treated for Rectal Cancer

NCT00532987
View directory record Official record
Conditions
Rectal Cancer, Colon Cancer, Anal Cancer
Interventions
Questionnaire
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
30 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2009
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Feb 27, 2012 · Synced Sep 20, 2026, 5:49 PM EDT
Recruiting Not applicable Interventional

Nutritional Prehabilitation to Improve Cancer Outcomes (N-PICO)

NCT07072377
View directory record Official record
Conditions
Malnutrition, Cancer-related Malnutrition, Quality of Life (QOL), Nutritional Support, Nutritional Interventions, Rural Health
Interventions
Intensity of Nutritional Intervention, Remote or In-Person
Behavioral
Lead sponsor
University of Vermont Medical Center
Other
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Sep 20, 2026, 5:49 PM EDT
Not listed Not applicable Interventional

Self-care App for Family Members of ICU Patients.

NCT04316767
View directory record Official record
Conditions
Post Intensive Care Unit Syndrome
Interventions
App Intervention
Behavioral
Lead sponsor
Kent State University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Akron, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 1, 2020 · Synced Sep 20, 2026, 5:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Probiotics and Health-related Quality of Life in Individuals With Seasonal Allergies

NCT02349711
View directory record Official record
Conditions
Healthy
Interventions
Probiotic mixture, Placebo
Dietary Supplement
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 60 Years
Enrollment
224 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 8, 2017 · Synced Sep 20, 2026, 5:49 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Study on the Impact of Patient Navigators on the Health Education and Quality of Life in Formerly Incarcerated Patients

NCT02259634
View directory record Official record
Conditions
HIV/AIDS, Diabetes Mellitus, Hypertension, Substance Use
Interventions
Patient Navigation
Behavioral
Lead sponsor
St. Luke's-Roosevelt Hospital Center
Other
Eligibility
18 Years and older
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 19, 2015 · Synced Sep 20, 2026, 5:49 PM EDT
Completed No phase listed Observational

A Disease Registry of Patients With Mantle Cell Lymphoma

NCT03816683
View directory record Official record
Conditions
Mantle Cell Lymphoma
Interventions
Not listed
Lead sponsor
AstraZeneca
Industry
Eligibility
18 Years to 130 Years
Enrollment
227 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
32
States / cities
Montgomery, Alabama • Clovis, California • Boulder, Colorado + 26 more
Source: ClinicalTrials.gov public record
Updated Nov 13, 2025 · Synced Sep 20, 2026, 5:49 PM EDT
Completed No phase listed Observational

Pyruvate Kinase Deficiency Natural History Study

NCT02053480
View directory record Official record
Conditions
Pyruvate Kinase Deficiency, Congenital Non-Spherocytic Hemolytic Anemia
Interventions
Not listed
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Not listed
Enrollment
254 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
19
States / cities
Phoenix, Arizona • Palo Alto, California • Atlanta, Georgia + 16 more
Source: ClinicalTrials.gov public record
Updated May 21, 2020 · Synced Sep 20, 2026, 5:49 PM EDT
Terminated Not applicable Interventional

Aquatic vs. Land Locomotor Training Overground Locomotor Training in Improving Ambulatory Function and Health-Related Quality of Life

NCT02774603
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Aquatic Locomotor Training, Land Locomotor Training
Other
Lead sponsor
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Other
Eligibility
18 Years to 65 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 8, 2018 · Synced Sep 20, 2026, 5:49 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

How Does Perimenopausal Menorrhagia Affect Women's Quality of Life and Cognitive Function?

NCT06798584
View directory record Official record
Conditions
Iron Deficiency Anemia Treatment, Iron Deficiency, Iron Deficiency (Without Anemia)
Interventions
FeoSol Original Iron Supplement Tablets, 21st Century Gelatin Capsules
Dietary Supplement
Lead sponsor
Purdue University
Other
Eligibility
18 Years and older · Female only
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 12, 2025 · Synced Sep 20, 2026, 5:49 PM EDT
Completed No phase listed Observational

Health-related Quality of Life, Symptom Severity, and Pain Among Patients With PIK3CA-related Overgrowth Spectrum: A Mixed-methods Observational Study

NCT05294289
View directory record Official record
Conditions
PIK3CA-related Overgrowth Spectrum
Interventions
Alpelisib
Other
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
5 Years to 99 Years
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
East Hanover, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 23, 2025 · Synced Sep 20, 2026, 5:49 PM EDT
Completed No phase listed Observational

Outcomes in Liver Disease Patient With and Without HIV Co-infection-Sub Study 2: HCV Treatment: Health Related Quality

NCT02427204
View directory record Official record
Conditions
Hepatitis C Infection
Interventions
Not listed
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 25, 2019 · Synced Sep 20, 2026, 5:49 PM EDT