Independent directory Public ClinicalTrials.gov records United States
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Showing 1–24 of 312 matching trials from the live ClinicalTrials.gov search.
Completed Not applicable Interventional Accepts healthy volunteers

Physical Activity and Cognition Study

NCT02773121
Conditions
Aging
Interventions
Physical Activity
Behavioral
Lead sponsor
Boston University
Other
Eligibility
55 Years to 85 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Terminated Not applicable Interventional Accepts healthy volunteers

Effect of Selenium Intervention on Inflammation in Older Adults

NCT01289925
Conditions
Inflammation
Interventions
Selenium, Sugar Pill Placebo
Dietary Supplement · Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
70 Years to 110 Years
Enrollment
182 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2012
U.S. locations
1
States / cities
Baltimore, Maryland
Recruiting Not applicable Interventional Accepts healthy volunteers

Ultrasound for Healthy Aging

NCT07168525
Conditions
Aging
Interventions
Ultrasound spa, Sham ultrasound spa
Device · Other
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
70 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
San Antonio, Texas
Recruiting No phase listed Observational Accepts healthy volunteers

Molecular Indicators of Systematic Fitness

NCT07393841
Conditions
Healthy Adult, Fitness Testing, Athlete, Aging, Exercise Physiology, Human Performance
Interventions
There is no intervention.
Other
Lead sponsor
VO Health, Inc.
Industry
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
New Haven, Connecticut
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Exploring How Osteopathic Manipulative Treatment May Affect Spinal Fluid Flow: An MRI Study

NCT07629765
Conditions
Osteopathic Manipulative Treatment (OMT) Effects on Cerebrospinal Fluid (CSF) Dynamics
Interventions
Osteopathic Manipulative Treatment (OMT)
Other
Lead sponsor
Edward Via Virginia College of Osteopathic Medicine
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Auburn, Alabama
Recruiting No phase listed Observational Accepts healthy volunteers

Tau PET in Imaging and Cognition: Healthy Adults From 55-90

NCT03372317
Conditions
Mild Cognitive Impairment, Aging
Interventions
18F-MK-6240
Drug
Lead sponsor
Yaakov Stern
Other
Eligibility
55 Years to 90 Years
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2027
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Accepts healthy volunteers

Development of Physical Activity Features for Ear-worn Devices

NCT05350046
Conditions
Hearing Loss, Well Aging
Interventions
Ear-worn prototype devices
Device
Lead sponsor
57GGardner
Industry
Eligibility
40 Years to 85 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Fremont, California
Completed Not applicable Interventional Accepts healthy volunteers

Healthy Lifetime - Sustainability and Quality Study

NCT05071326
Conditions
Aging Well
Interventions
Nurse-led health coaching
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
30 Years and older
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Aging, Facial Aging
Interventions
Not listed
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
10,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Sleep and Healthy Aging Research on Depression for Younger Women

NCT03848715
Conditions
Anhedonia, Depression
Interventions
Endotoxin, Placebo
Biological
Lead sponsor
University of California, Los Angeles
Other
Eligibility
25 Years to 44 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Completed Not applicable Interventional Accepts healthy volunteers

Aquatic Exercise for Cognition and Mobility in Older Adults

NCT05501249
Conditions
Aging Well, Aging Problems, Cognitive Change, Gait, Unsteady, Mobility Limitation
Interventions
Aquatic Integrated Cognitive Motor Training
Behavioral
Lead sponsor
Emily Dunlap
Other
Eligibility
65 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Austin, Texas
Recruiting Not applicable Interventional Accepts healthy volunteers

Neuromodulation and Fatigue

NCT05487131
Conditions
Healthy Aging, Fatigue
Interventions
electrical stimulation
Behavioral
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 50 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Norman, Oklahoma
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

The Physiological Chronobiome Modified by Age, Sex and Under Evoked Conditions

NCT04225442
Conditions
Healthy, Healthy Aging
Interventions
Fatty meal to challenge the physiological chronobiome in healthy young and old
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 75 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2028
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Completed No phase listed Observational

Lactate for Energy and Neurocognition

NCT05207397
Conditions
Healthy Aging, Alzheimer Disease
Interventions
Lactate infusion
Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
60 Years to 95 Years
Enrollment
24 participants
Timeline
2023 – 2024
U.S. locations
1
States / cities
Kansas City, Kansas
Conditions
Arthritis, Diabetes, Hypertension, Preventive Behaviors
Interventions
AFEP, "10 Keys" to Healthy Aging
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
50 Years and older
Enrollment
462 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Allegheny County Primarily, Pennsylvania
Conditions
Healthy Aging, Alzheimer's Disease (AD)
Interventions
Web-based Cognitive Training (with strategy), Web-based Cognitive Training (without strategy)
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
60 Years to 75 Years
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Newark, New Jersey
Recruiting Not applicable Interventional Accepts healthy volunteers

Balance Control and Recovery in Diabetes Peripheral Neuropathy

NCT06544876
Conditions
Diabetic Peripheral Neuropathy, Diabetic Peripheral Neuropathy Type 2, Diabetic Peripheral Neuropathy Type 2 - Uncontrolled, Healthy Aging
Interventions
sit-to-stand, stand to sit, standing perturbation, MRI of sciatic nerve
Behavioral · Other
Lead sponsor
Lisa Griffin
Other
Eligibility
50 Years to 99 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Austin, Texas
Completed Phase 2 Interventional Accepts healthy volunteers

The CHAT (Community Health Advice by Telephone) Study

NCT00131092
Conditions
Health Behavior, Healthy
Interventions
The Stanford Active Choices program, The TLC system
Behavioral
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
55 Years and older
Enrollment
225 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2003
U.S. locations
1
States / cities
Stanford, California
Not listed Not applicable Interventional Accepts healthy volunteers

IV Administration of ChromaDex's Niagen® as Compared to NAD+

NCT06382688
Conditions
Healthy Aging
Interventions
NAD+ (nicotinamide adenine dinucleotide) IV, Niagen® (nicotinamide riboside) IV, Niagen® (nicotinamide riboside) oral, Placebo
Dietary Supplement · Other
Lead sponsor
Nutraceuticals Research Institute
Other
Eligibility
40 Years and older
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Franklin, Tennessee
Completed No phase listed Observational Accepts healthy volunteers

Patterns of Natural Aging and the Role of Senescence Registry

NCT05123859
Conditions
Healthy Aging
Interventions
Not listed
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
25 Years to 85 Years
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Conditions
Healthy Aging, Inflammaging, Metabolic Health, Quercetin, Coenzyme Q10
Interventions
Quercetin (dietary supplement), Coenzyme Q10, Rice Flour
Dietary Supplement
Lead sponsor
Applied Science & Performance Institute
Industry
Eligibility
50 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Tampa, Florida
Recruiting Not applicable Interventional Accepts healthy volunteers

Multimodal Musical Stimulation for Healthy Neurocognitive Aging

NCT06229093
Conditions
Aging
Interventions
Gamma, Synchrony
Device
Lead sponsor
Northeastern University
Other
Eligibility
18 Years to 95 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Not listed Not applicable Interventional Accepts healthy volunteers Results available

The Safety and Efficacy Study of RiaGev in Healthy Adults

NCT04483011
Conditions
Metabolic Syndrome, Premature Aging
Interventions
RiaGev
Dietary Supplement
Lead sponsor
Bioenergy Life Science, Inc.
Industry
Eligibility
36 Years to 65 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Saint Paul, Minnesota
Completed No phase listed Observational Accepts healthy volunteers

Nutrient Regulation of Amino Acid Transporters in Aging Human Skeletal Muscle

NCT01669590
Conditions
Healthy
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 75 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
1
States / cities
Salt Lake City, Utah