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Showing 1–16 of 16 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Healthy Ankle Clear all
Not listed No phase listed Observational Accepts healthy volunteers

The Effect of Estrogen and Progesterone Levels on Knee and Ankle Joint Laxity

NCT00005923
View directory record Official record
Conditions
Healthy
Interventions
Not listed
Lead sponsor
National Center for Research Resources (NCRR)
NIH
Eligibility
15 Years to 23 Years
Healthy volunteers
Accepts healthy volunteers
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Jun 23, 2005 · Synced Jul 22, 2026, 9:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of a Talocrural Thrust Manipulation on Lateral Ankle Ligament Integrity in a Subgroup of Healthy Individuals

NCT03731767
View directory record Official record
Conditions
Healthy
Interventions
Distraction thrust manipulation
Procedure
Lead sponsor
Florida Gulf Coast University
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Cape Coral, Florida
Source: ClinicalTrials.gov public record
Updated Jul 21, 2020 · Synced Jul 22, 2026, 9:13 AM EDT
Completed Not applicable Interventional Results available

Iterative Design of Custom Dynamic Orthoses

NCT04800510
View directory record Official record
Conditions
Adult ALL, Healthy
Interventions
Carbon Fiber Custom Dynamic Orthosis (CDO)
Device
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 50 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jan 29, 2026 · Synced Jul 22, 2026, 9:13 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Gait Adaptations to Passive Dynamic Ankle-Foot Orthosis Use

NCT00115401
View directory record Official record
Conditions
Joint Instability
Interventions
Not listed
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
5 Years and older
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Jul 22, 2026, 9:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Different Types of Cupping Therapy and Ankle Range of Motion

NCT06513078
View directory record Official record
Conditions
Healthy
Interventions
Static cupping, Static sham cupping, Dynamic cupping, Dynamic sham cupping
Other
Lead sponsor
Northern Michigan University
Other
Eligibility
18 Years and older
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Marquette, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 24, 2024 · Synced Jul 22, 2026, 9:13 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Development of a Real-time Controller to Estimate Walking Performance Using a Bilateral Ankle Exoskeleton

NCT07393971
View directory record Official record
Conditions
Healthy Young Adults
Interventions
Adaptive Torque Control System for Ankle Exoskeleton
Device
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years to 35 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Jul 22, 2026, 9:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Do Rocker Bottom Shoes and Ankle-Foot Orthoses Reduce Pain and Improve Mobility for Ankle Osteoarthritis Patients

NCT03524729
View directory record Official record
Conditions
Ankle Osteoarthritis, Healthy Ankles
Interventions
Rocker bottom shoe, Ankle foot orthosis, Standard walking shoe
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Jul 22, 2026, 9:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Progressing Ankle Brace Restriction on Walking and Running Gait Characteristics in Healthy Individuals

NCT03641066
View directory record Official record
Conditions
Ankle Sprains
Interventions
Ankle Brace
Device
Lead sponsor
Sport and Spine Rehab Clinical Research Foundation
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 24, 2019 · Synced Jul 22, 2026, 9:13 AM EDT
Not yet recruiting No phase listed Observational Accepts healthy volunteers

Validation of a Portable Ankle Arthrometer

NCT07163897
View directory record Official record
Conditions
Chronic Ankle Instability, CAI, Ankle Sprain, Healthy
Interventions
Cobra Ankle Arthrometer
Device
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 40 Years
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 8, 2025 · Synced Jul 22, 2026, 9:13 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Reliability of Force Measurement Within the Carbon Fiber Orthosis Proximal Cuff

NCT06127264
View directory record Official record
Conditions
Healthy, Ankle Foot Orthosis (AFO), Peripheral Neuropathy
Interventions
Carbon Fiber Custom Dynamic Orthosis (CDO)
Device
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 90 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Dec 30, 2025 · Synced Jul 22, 2026, 9:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Heel Wedges and Carbon Fiber Custom Dynamic Orthoses to Control Knee Biomechanics

NCT05209360
View directory record Official record
Conditions
Adult ALL, Healthy
Interventions
Medial or Lateral Wedge, Carbon Fiber Custom Dynamic Orthosis
Device
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 45 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jan 29, 2024 · Synced Jul 22, 2026, 9:13 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Effect of Cognitive Tasks on Single Limb Balance

NCT07084220
View directory record Official record
Conditions
Chronic Ankle Instability, CAI, Healthy Participants
Interventions
Not listed
Lead sponsor
Towson University
Other
Eligibility
18 Years to 40 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Towson, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 23, 2025 · Synced Jul 22, 2026, 9:13 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

An Evaluation Of Healthy Ankle Motion And Morphology

NCT03619382
View directory record Official record
Conditions
Healthy Ankle
Interventions
Cone Beam Computed Tomography, Radiographs
Radiation
Lead sponsor
Paragon 28
Industry
Eligibility
18 Years to 65 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Atlantis, Florida
Source: ClinicalTrials.gov public record
Updated Jun 17, 2021 · Synced Jul 22, 2026, 9:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Malleo-Lok Stiffness on Lower Limb Mechanics

NCT04806100
View directory record Official record
Conditions
Adult ALL, Healthy
Interventions
Malleo-Lok
Device
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 45 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jun 14, 2023 · Synced Jul 22, 2026, 9:13 AM EDT
Completed Not applicable Interventional Results available

Use of Platelet-Rich Plasma (PRP) and Platelet-Poor Plasma (PPP) to Prevent Infection and Delayed Wound Healing

NCT01639144
View directory record Official record
Conditions
Elective Foot and Ankle Surgery.
Interventions
PRP and PPP
Biological
Lead sponsor
Gary M. Kiebzak, Ph.D.
Other
Eligibility
18 Years to 80 Years
Enrollment
515 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Coral Gables, Florida
Source: ClinicalTrials.gov public record
Updated May 21, 2015 · Synced Jul 22, 2026, 9:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparative Effect of Carbon Fiber Orthosis Cuff Design on Preference, Comfort, and Mechanics

NCT05456295
View directory record Official record
Conditions
Healthy, Lower Limb Injury, Post-Traumatic Osteoarthritis
Interventions
Carbon Fiber Custom Dynamic Orthosis (CDO)
Device
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 65 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jan 14, 2026 · Synced Jul 22, 2026, 9:13 AM EDT