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ClinicalTrials.gov public records Last synced Oct 15, 2026, 11:36 AM EDT

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Showing 361–384 of 511 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Healthy Older Adults Clear all
Completed Phase 1 Interventional Accepts healthy volunteers

Open-Label, Placebo-Controlled, Parallel Group Study in Healthy Volunteers to Evaluate the Effects of Two Single MT 400 or Naproxen Sodium Tablets

NCT00596245
View directory record Official record
Conditions
Healthy
Interventions
MT400
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 35 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Apr 16, 2015 · Synced Oct 15, 2026, 11:36 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

To Assess the Effect of Food on the Pharmacokinetics of Selumetinib (AZD6244; ARRY-142886) (Hyd-Sulfate) in Healthy Male Volunteers

NCT01974349
View directory record Official record
Conditions
Solid Tumours
Interventions
selumetinib (oral)
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
18 Years to 45 Years · Male only
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Overland Park, Kansas
Source: ClinicalTrials.gov public record
Updated Aug 13, 2014 · Synced Oct 15, 2026, 11:36 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Alcohol Sensitivity Among Older Adults Who Consume Alcohol

NCT07636447
View directory record Official record
Conditions
Healthy Adult Participants
Interventions
Alcohol (Oral), Placebo Control
Other
Lead sponsor
University of Florida
Other
Eligibility
65 Years to 80 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 15, 2026, 11:36 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Alternative Schedule Study For VLA15, a Vaccine Candidate Against Lyme Borreliosis

NCT03970733
View directory record Official record
Conditions
Lyme Borreliosis
Interventions
VLA15, Placebo
Biological
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 65 Years
Enrollment
246 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
5
States / cities
Milford, Connecticut • Stamford, Connecticut • Binghamton, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 21, 2023 · Synced Oct 15, 2026, 11:36 AM EDT
Completed Not applicable Interventional

'Food, Fun, Fresh, Family' Program for Healthy Eating and Growth for Elementary-age Children.

NCT06010784
View directory record Official record
Conditions
Diet, Healthy Growth
Interventions
Family support, BGCAA's after-school program with CATCH curriculum
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
5 Years to 11 Years
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 15, 2026, 11:36 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Effect of Sugar Sweetened and Diet Beverages Consumed as Part of a Weight-Maintenance Diet on Fat Storage

NCT02252952
View directory record Official record
Conditions
Focus: Understanding the Obesogenic Potential of Sugars and Non-caloric Sweeteners
Interventions
Beverage Consumption
Other
Lead sponsor
Rippe Lifestyle Institute
Industry
Eligibility
20 Years to 50 Years
Enrollment
99 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2013
U.S. locations
1
States / cities
Celebration, Florida
Source: ClinicalTrials.gov public record
Updated Dec 16, 2014 · Synced Oct 15, 2026, 11:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cognitive Multi-Tasking Training in Healthy Older Adults

NCT04195230
View directory record Official record
Conditions
Age-related Cognitive Decline
Interventions
Multi-tasking Training
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
60 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 28, 2022 · Synced Oct 15, 2026, 11:36 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Effects of Donepezil HCL on Task-Activated fMRI Brain Activation in Healthy Older Adults at Genetic Risk for Alzheimer's Disease

NCT02087865
View directory record Official record
Conditions
Genetic Risk for Alzheimer's Disease
Interventions
donepezil HCL, Placebo
Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
60 Years to 75 Years
Enrollment
89 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2021
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 30, 2023 · Synced Oct 15, 2026, 11:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Adaptation of a Health Promotion Nutrition Program for Older Adults

NCT03205007
View directory record Official record
Conditions
Nutrition Disorders in Old Age
Interventions
Health promotion nutrition program
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
60 Years and older
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
2
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 24, 2019 · Synced Oct 15, 2026, 11:36 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

A Study to Evaluate the Safety, Tolerability, and Immunogenicity of V114 When Administered Concomitantly With Influenza Vaccine in Healthy Adults 50 Years of Age or Older (V114-021/PNEU-FLU)

NCT03615482
View directory record Official record
Conditions
Pneumococcal Infections
Interventions
V114, QIV, Matching Placebo for V114
Biological
Lead sponsor
Merck Sharp & Dohme LLC
Industry
Eligibility
50 Years and older
Enrollment
1,200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
45
States / cities
Birmingham, Alabama • Chandler, Arizona • Mesa, Arizona + 39 more
Source: ClinicalTrials.gov public record
Updated May 22, 2024 · Synced Oct 15, 2026, 11:36 AM EDT
Active, not recruiting Phase 3 Interventional Accepts healthy volunteers

A Clinical Study to Evaluate the Safety, Tolerability, and Immunogenicity of VAX-31 With Influenza Vaccine in Adults ≥ 50 Years of Age

NCT07365826
View directory record Official record
Conditions
Pneumococcal Vaccines
Interventions
31-valent pneumococcal conjugate vaccine, Seasonal Influenza Vaccine (SIV) (Flublok), Placebo
Biological
Lead sponsor
Vaxcyte, Inc.
Industry
Eligibility
50 Years and older
Enrollment
1,390 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
25
States / cities
Phoenix, Arizona • Fort Collins, Colorado • DeLand, Florida + 22 more
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Oct 15, 2026, 11:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

MBCT Intervention: Healthy Mind, Healthy Living

NCT05965349
View directory record Official record
Conditions
Mindfulness Based Cognitive Therapy, Depression, Sleep, Anxiety Depression
Interventions
Healthy Mind, Healthy Living
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
50 Years to 89 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 3, 2025 · Synced Oct 15, 2026, 11:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Probiotics (L. Gasseri, B. Bifidum, B. Longum) on Immune and Intestinal Health in Healthy Older Adults

NCT01662206
View directory record Official record
Conditions
Healthy
Interventions
Probiotic, Placebo
Dietary Supplement
Lead sponsor
University of Florida
Other
Eligibility
65 Years to 80 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 17, 2013 · Synced Oct 15, 2026, 11:36 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

First-In-Human Study Of Single And Multiple Ascending Doses Of PF-06751979

NCT02509117
View directory record Official record
Conditions
Healthy Subjects
Interventions
PF-06751979 single ascending dose, Placebo single dose, PF-06751979 multiple ascending dose, Placebo multiple dose, PF-06751979 multiple dose
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 85 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
2
States / cities
Glendale, California
Source: ClinicalTrials.gov public record
Updated Nov 1, 2018 · Synced Oct 15, 2026, 11:36 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

The Healthy Elderly Longevity Cohort

NCT01004133
View directory record Official record
Conditions
Healthy
Interventions
Not listed
Lead sponsor
Scripps Translational Science Institute
Other
Eligibility
80 Years and older
Enrollment
5,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2030
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jan 17, 2025 · Synced Oct 15, 2026, 11:36 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Physical and Cognitive Aging Study in Older Adults

NCT06726616
View directory record Official record
Conditions
Older Adults (65 Years and Older), Hispanic Americans, Cognitive Aging, Aging, Healthy, Exercise
Interventions
Not listed
Lead sponsor
University of Florida
Other
Eligibility
55 Years to 85 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Oct 15, 2026, 11:36 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

A Study To Investigate A Clostridium Difficile Vaccine In Healthy Adults Aged 50 to 85 Years, Who Will Each Receive 3 Doses Of Vaccine.

NCT02117570
View directory record Official record
Conditions
Clostridium Difficile Associated Disease
Interventions
Clostridium difficile vaccine, Placebo
Biological
Lead sponsor
Pfizer
Industry
Eligibility
50 Years to 85 Years
Enrollment
185 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
12
States / cities
DeLand, Florida • Savannah, Georgia • Stockbridge, Georgia + 9 more
Source: ClinicalTrials.gov public record
Updated Jan 30, 2017 · Synced Oct 15, 2026, 11:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

HealthyWE: Achieving a Healthy Weight and Reducing Pain

NCT07095673
View directory record Official record
Conditions
Obesity &Amp; Overweight
Interventions
HealthyWE
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
19 Years and older
Enrollment
89 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Camden, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Oct 15, 2026, 11:36 AM EDT
Completed Not applicable Interventional

The Effects of a Mobile Health Intervention and Health Coach Text Messaging on Cardiovascular Risk of Older Adults

NCT03720327
View directory record Official record
Conditions
Cardiovascular Diseases, Cardiovascular Risk Factor
Interventions
Get FIT+
Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
60 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
5
States / cities
Anaheim, California • Irvine, California • Orange, California + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 18, 2022 · Synced Oct 15, 2026, 11:36 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

A Study of IVX-A12 in Adults Participants

NCT06481579
View directory record Official record
Conditions
Healthy Participants
Interventions
IVX-A12, Licensed RSV Vaccine
Biological
Lead sponsor
Icosavax, Inc.
Industry
Eligibility
60 Years and older
Enrollment
143 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
5
States / cities
Anaheim, California • Rolling Hills Estates, California • Hollywood, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 26, 2025 · Synced Oct 15, 2026, 11:36 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Safety and Immunogenicity of Two Doses of H5N1 Influenza Vaccine in Elderly Subjects

NCT01766921
View directory record Official record
Conditions
Pandemic H5N1 Influenza
Interventions
Adjuvanted H5N1 pandemic influenza vaccine
Biological
Lead sponsor
Novartis Vaccines
Industry
Eligibility
65 Years and older
Enrollment
1,393 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
12
States / cities
Phoenix, Arizona • Hollywood, Florida • Wichita, Kansas + 7 more
Source: ClinicalTrials.gov public record
Updated Jan 30, 2019 · Synced Oct 15, 2026, 11:36 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

QA102 Phase 1 Study in Healthy Young and Older Adult Subjects

NCT04894071
View directory record Official record
Conditions
Age-related Macular Degeneration
Interventions
QA102, Placebo
Drug
Lead sponsor
Smilebiotek Zhuhai Limited
Industry
Eligibility
18 Years to 75 Years
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jan 14, 2022 · Synced Oct 15, 2026, 11:36 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Evaluation of a Single Vaccination With One of Three Ascending Dose Levels of a 4-Antigen Staphylococcus Aureus Vaccine (SA4Ag) in Healthy Adults Aged 18 to <65 Years

NCT01364571
View directory record Official record
Conditions
Staphylococcal Infections
Interventions
SA4Ag vaccine low dose, Blood draw, Colonization swab sample, SA4Ag vaccine mid dose, Blood sample, SA4Ag vaccine high dose, Placebo
Biological · Procedure
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 64 Years
Enrollment
456 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
16
States / cities
Hollywood, Florida • South Miami, Florida • Overland Park, Kansas + 10 more
Source: ClinicalTrials.gov public record
Updated Mar 4, 2019 · Synced Oct 15, 2026, 11:36 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Study on the Safety and Immune Response to an mRNA-based RSV Investigational Vaccine in Healthy Adults Aged 18-45 Years

NCT06573281
View directory record Official record
Conditions
Respiratory Syncytial Virus Infections
Interventions
Investigational RSV vaccine 1, Investigational RSV vaccine 2, Investigational RSV vaccine 3, Investigational RSV vaccine 4, Investigational RSV vaccine 5, Investigational RSV vaccine 6, Placebo
Biological · Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 45 Years
Enrollment
213 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
5
States / cities
Rolling Hills Estates, California • Atlanta, Georgia • Lenexa, Kansas + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Oct 15, 2026, 11:36 AM EDT