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ClinicalTrials.gov public records Last synced Oct 22, 2026, 9:27 PM EDT

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Showing 313–336 of 684 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Hearing Disorder Clear all
Completed No phase listed Interventional Results available

Non-significant Risk Study of a Cochlear Implant Headpiece

NCT05488535
View directory record Official record
Conditions
Hearing Loss, Sensorineural Hearing Loss
Interventions
cochlear implant headpiece
Device
Lead sponsor
Advanced Bionics
Industry
Eligibility
Not listed
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Valencia, California
Source: ClinicalTrials.gov public record
Updated Nov 14, 2023 · Synced Oct 22, 2026, 9:27 PM EDT
Completed Phase 1Phase 2 Interventional

OTO-413 in Subjects With Speech-in-Noise Hearing Impairment

NCT04129775
View directory record Official record
Conditions
Sensorineural Hearing Loss
Interventions
OTO-413, Placebo
Drug
Lead sponsor
Otonomy, Inc.
Industry
Eligibility
21 Years to 64 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
8
States / cities
Colorado Springs, Colorado • Hollywood, Florida • Miami, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Oct 27, 2022 · Synced Oct 22, 2026, 9:27 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Early Communication Intervention for Toddlers With Hearing Loss

NCT03803943
View directory record Official record
Conditions
Hearing Loss, Bilateral
Interventions
Parent-Implemented Communication Intervention (PICT), No Intervention - Business-as-usual control
Behavioral · Other
Lead sponsor
Northwestern University
Other
Eligibility
12 Months to 18 Months
Enrollment
210 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 22, 2026, 9:27 PM EDT
Completed Phase 1Phase 2 Interventional

Study to Determine the Efficacy and Safety of ELS-M11 in Acute Migraine

NCT02057315
View directory record Official record
Conditions
Migraine Headaches
Interventions
ELS-M11, Placebo
Drug
Lead sponsor
Achelios Therapeutics
Industry
Eligibility
18 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
2
States / cities
Ann Arbor, Michigan • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 11, 2017 · Synced Oct 22, 2026, 9:27 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Connectivity Analysis for Investigation of Auditory Impairment in Epilepsy

NCT01212068
View directory record Official record
Conditions
Brain Mapping, Intracranial Central Nervous System Disorder, Epilepsy, Auditory Perceptual Disorder, Hearing Disorder
Interventions
Not listed
Lead sponsor
National Institute on Deafness and Other Communication Disorders (NIDCD)
NIH
Eligibility
18 Years to 50 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2017
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 6, 2017 · Synced Oct 22, 2026, 9:27 PM EDT
Terminated Not applicable Interventional Results available

Venous Sinus Stenting To Treat Intractable Pulsatile Tinnitus Caused By Venous Sinus Stenosis

NCT02734576
View directory record Official record
Conditions
Tinnitus, Pulsatile Tinnitus, Venous Sinus Stenosis, Dural Sinus Stenosis
Interventions
Venous Sinus Stenting with the Precise Pro Stent
Device
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 2, 2021 · Synced Oct 22, 2026, 9:27 PM EDT
Withdrawn Not applicable Interventional

Mindfulness Intervention and Symptom Variability in Hearing

NCT04281225
View directory record Official record
Conditions
Hearing Loss
Interventions
Attention to Variability (ATV), Placebo
Behavioral · Other
Lead sponsor
Harvard University
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 17, 2022 · Synced Oct 22, 2026, 9:27 PM EDT
No Longer Available No phase listed Expanded access

Compassionate Use Arm - ABI541 ABI for 10 NF2 Patients

NCT02589912
View directory record Official record
Conditions
Neurofibromatosis Type 2, Severe Profound Sensorineural Hearing Loss
Interventions
Nucleus Profile ABI541 Auditory Brainstem Implant
Device
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
12 Years to 80 Years
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 6, 2019 · Synced Oct 22, 2026, 9:27 PM EDT
Completed No phase listed Interventional Results available

Evaluation of Remote Fitting in Adult and Pediatric Users of the HiResolution Bionic Ear System

NCT05034731
View directory record Official record
Conditions
Hearing Loss, Ear Diseases, Hearing Disorders, Otolaryngological Disease
Interventions
Remote Fitting, In-Office Fitting
Device
Lead sponsor
Advanced Bionics
Industry
Eligibility
13 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 21, 2023 · Synced Oct 22, 2026, 9:27 PM EDT
Completed Phase 1 Interventional

FX-322 in Adults With Severe Sensorineural Hearing Loss

NCT04629664
View directory record Official record
Conditions
Hearing Loss, Sensorineural, Noise Induced Hearing Loss, Sudden Hearing Loss
Interventions
FX-322, Placebo
Drug · Other
Lead sponsor
Frequency Therapeutics
Industry
Eligibility
18 Years to 65 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
7
States / cities
Novi, Michigan • Omaha, Nebraska • Amherst, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 1, 2022 · Synced Oct 22, 2026, 9:27 PM EDT
Withdrawn No phase listed Observational

Hearing Changes After Surgery

NCT04322747
View directory record Official record
Conditions
Hearing Loss
Interventions
Distortion product otoacoustic emissions (DPOAE)
Diagnostic Test
Lead sponsor
Gateway Biotechnology, Inc.
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 9, 2022 · Synced Oct 22, 2026, 9:27 PM EDT
Completed Not applicable Interventional Results available

Expanded Indications in the Adult Cochlear Implant Population

NCT03236909
View directory record Official record
Conditions
Hearing Loss, Sensorineural
Interventions
MED-EL SYNCHRONY/SYNCHRONY PIN Cochlear Implant System
Device
Lead sponsor
Med-El Corporation
Industry
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
4
States / cities
Miami, Florida • Chapel Hill, North Carolina • Nashville, Tennessee + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 24, 2025 · Synced Oct 22, 2026, 9:27 PM EDT
Completed Phase 1 Interventional

NAC to Prevent Cisplatin-induced Hearing Loss

NCT02094625
View directory record Official record
Conditions
Neuroectodermal Tumors, Primitive, Liver Neoplasms, Osteosarcoma, Other Childhood Cancers Using Cisplatin-based Regimens
Interventions
N-Acetylcysteine
Drug
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
1 Year to 21 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 18, 2023 · Synced Oct 22, 2026, 9:27 PM EDT
Recruiting Not applicable Interventional

Benefits of Choir for Older Adults With Unaddressed Hearing Loss (WP2)

NCT06580847
View directory record Official record
Conditions
Hearing Loss, Age-Related, Speech Intelligibility, Psychosocial Functioning
Interventions
Group Singing, Audiobook Club
Behavioral
Lead sponsor
Toronto Metropolitan University
Other
Eligibility
60 Years and older
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 18, 2025 · Synced Oct 22, 2026, 9:27 PM EDT
Completed Not applicable Interventional Results available

Clinical Investigation of New CI Delivery Models in an Adult Nucleus CI Population

NCT03304106
View directory record Official record
Conditions
Sensorineural Hearing Loss, Bilateral, Cochlear Implant
Interventions
Commercially available cochlear implant and AI system
Device
Lead sponsor
Cochlear
Industry
Eligibility
12 Years and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
9
States / cities
Englewood, Colorado • Baltimore, Maryland • Ann Arbor, Michigan + 6 more
Source: ClinicalTrials.gov public record
Updated Oct 29, 2020 · Synced Oct 22, 2026, 9:27 PM EDT
Completed Phase 4 Interventional Results available

Safety and Tolerability Study of Daily Dosing Rimegepant in Episodic Migraine Prevention

NCT05207865
View directory record Official record
Conditions
Migraine, Episodic Migraine, Phonophobia, Photophobia
Interventions
Rimegepant
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years and older
Enrollment
441 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
19
States / cities
Phoenix, Arizona • Hawthorne, California • North Hollywood, California + 15 more
Source: ClinicalTrials.gov public record
Updated Sep 3, 2025 · Synced Oct 22, 2026, 9:27 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Transcranial Magnetic Stimulation for Tinnitus

NCT01104207
View directory record Official record
Conditions
Tinnitus
Interventions
repetitive transcranial magnetic stimulation (rTMS), placebo rTMS
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 29, 2017 · Synced Oct 22, 2026, 9:27 PM EDT
Not listed Not applicable Interventional

Treatment of Tinnitus With Noninvasive Neuromodulation and Listening Therapy

NCT04934371
View directory record Official record
Conditions
Tinnitus, Subjective, Hyperacusis, Hearing Disorders
Interventions
Transcranial Direct Current Stimulation (tDCS), Sham TDCS
Device
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated May 8, 2024 · Synced Oct 22, 2026, 9:27 PM EDT
Terminated Not applicable Interventional

Investigating the DNN Noise Reduction Feature in Phonak Hearing Aids Using Ecological Momentary Assessment

NCT07526428
View directory record Official record
Conditions
Hearing Loss
Interventions
Phonak Audeo Infinio Hearing Aid, Competitor Device A
Device
Lead sponsor
Sonova AG
Industry
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Aurora, Illinois
Source: ClinicalTrials.gov public record
Updated May 29, 2026 · Synced Oct 22, 2026, 9:27 PM EDT
Completed No phase listed Observational

Natural History and Genetic Studies of Usher Syndrome

NCT00106743
View directory record Official record
Conditions
Retinitis Pigmentosa Syndromic, Congenital Deafness, Usher Syndrome, Retinitis Pigmentosa and Deafness, Retinitis Pigmentosa
Interventions
Not listed
Lead sponsor
National Eye Institute (NEI)
NIH
Eligibility
2 Years and older
Enrollment
249 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2019
U.S. locations
2
States / cities
Bethesda, Maryland • New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 12, 2019 · Synced Oct 22, 2026, 9:27 PM EDT
Active, not recruiting Not applicable Interventional

Investigation to Evaluate the Safety and Effectiveness of Cochlear Implantation in Children and Adults With Unilateral Hearing Loss/Single-sided Deafness

NCT05318417
View directory record Official record
Conditions
Hearing Loss, Unilateral, Deafness, Unilateral
Interventions
The Cochlear™ Nucleus® Cochlear Implant (CI) System
Device
Lead sponsor
Cochlear
Industry
Eligibility
5 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
6
States / cities
Palo Alto, California • Englewood, Colorado • Iowa City, Iowa + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 22, 2026, 9:27 PM EDT
Not listed Phase 2 Interventional

Cholesterol and Antioxidant Treatment in Patients With Smith-Lemli-Opitz Syndrome (SLOS)

NCT01773278
View directory record Official record
Conditions
Smith-Lemli-Opitz Syndrome, Cone-Rod Dystrophy, Hearing Loss
Interventions
Antioxidants, Cholesterol
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
Up to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2025
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated May 8, 2024 · Synced Oct 22, 2026, 9:27 PM EDT
Active, not recruiting Not applicable Interventional

Clinical Utility of Residual Hearing in the Cochlear Implant Ear

NCT04707885
View directory record Official record
Conditions
Hearing Loss, Sensorineural, Hearing Loss, Hearing Loss, Bilateral
Interventions
Electrocochleography
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 79 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
5
States / cities
Rochester, Minnesota • St Louis, Missouri • Chapel Hill, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Oct 22, 2026, 9:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Using Community Health Navigators to Advance Cancer Screening Adherence

NCT06492993
View directory record Official record
Conditions
Cancer, Deafness
Interventions
Education
Other
Lead sponsor
Gallaudet University
Other
Eligibility
45 Years to 80 Years
Enrollment
184 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Apr 2, 2026 · Synced Oct 22, 2026, 9:27 PM EDT