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ClinicalTrials.gov public records Last synced Oct 22, 2026, 4:27 AM EDT

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Showing 121–144 of 684 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Hearing Disorder Clear all
Recruiting Phase 2 Interventional

Atorvastatin to Reduce Cisplatin-Induced Hearing Loss Among Individuals With Head and Neck Cancer

NCT04915183
View directory record Official record
Conditions
Hearing Loss, Head and Neck Cancer
Interventions
Placebo, Atorvastatin
Other · Drug
Lead sponsor
National Institute on Deafness and Other Communication Disorders (NIDCD)
NIH
Eligibility
18 Years to 100 Years
Enrollment
224 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2030
U.S. locations
5
States / cities
Atlanta, Georgia • Baltimore, Maryland • Bethesda, Maryland + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 22, 2026, 4:27 AM EDT
Completed No phase listed Observational

Early Diagnosis of Steroid-Responsive & No-Responsive Hearing Loss

NCT00013468
View directory record Official record
Conditions
Hearing Loss
Interventions
Tinnitus
Procedure
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2003
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jan 21, 2009 · Synced Oct 22, 2026, 4:27 AM EDT
Completed Phase 2 Interventional Results available

FX-322 in Adults With Acquired Sensorineural Hearing Loss

NCT05086276
View directory record Official record
Conditions
Hearing Loss, Sensorineural, Noise Induced Hearing Loss, Sudden Hearing Loss
Interventions
FX-322, Placebo
Drug
Lead sponsor
Frequency Therapeutics
Industry
Eligibility
18 Years to 65 Years
Enrollment
142 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
26
States / cities
Tucson, Arizona • Fresno, California • Torrance, California + 23 more
Source: ClinicalTrials.gov public record
Updated Apr 21, 2023 · Synced Oct 22, 2026, 4:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cochlear Implantation in Pediatric Cases of Unilateral Hearing Loss

NCT02963974
View directory record Official record
Conditions
Hearing Loss, Unilateral
Interventions
Cochlear implant
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
42 Months to 78 Months
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 6, 2021 · Synced Oct 22, 2026, 4:27 AM EDT
Completed Not applicable Interventional Results available

Evaluating Benefits of Hearing Aid Microphone Directionality Technologies

NCT04953390
View directory record Official record
Conditions
Hearing Loss
Interventions
Phonak Audeo hearing aid, Phonak hearing aid with multiple directionality settings, adjustable via a mobile app
Device
Lead sponsor
Sonova AG
Industry
Eligibility
18 Years to 90 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Aurora, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 9, 2022 · Synced Oct 22, 2026, 4:27 AM EDT
Completed Not applicable Interventional

Hearing Aid Education and Adaptation System

NCT02839759
View directory record Official record
Conditions
Hearing Loss
Interventions
TELLYHealth
Other
Lead sponsor
Healthcare Technologies and Methods, LLC
Industry
Eligibility
50 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
2
States / cities
Gainesville, Florida • Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated May 14, 2020 · Synced Oct 22, 2026, 4:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Restoration of Spectral Resolution With Hearing-aid Amplification

NCT03850678
View directory record Official record
Conditions
Hearing Loss
Interventions
Hearing Aid
Device
Lead sponsor
University of Nebraska Lincoln
Other
Eligibility
40 Years to 75 Years
Enrollment
209 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Lincoln, Nebraska
Source: ClinicalTrials.gov public record
Updated Jan 14, 2025 · Synced Oct 22, 2026, 4:27 AM EDT
Completed Not applicable Interventional

Brief Cognitive Behavioral Therapy for People With Physical Disabilities

NCT05695430
View directory record Official record
Conditions
Suicide, Suicide, Attempted, Suicidal Ideation, Disability Physical, Disability Hearing, Disability, Vision
Interventions
Brief Cognitive Behavioral Therapy for People with Physical Disabilities
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 28, 2026 · Synced Oct 22, 2026, 4:27 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Safety, Tolerability and Efficacy for CGF166 in Patients With Unilateral or Bilateral Severe-to-profound Hearing Loss

NCT02132130
View directory record Official record
Conditions
Unilateral Severe to Profound Hearing Loss OR Bilateral Severe to Profound Hearing Loss
Interventions
CGF166
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years to 75 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
4
States / cities
Kansas City, Kansas • Baltimore, Maryland • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 8, 2021 · Synced Oct 22, 2026, 4:27 AM EDT
Not yet recruiting No phase listed Observational Accepts healthy volunteers

Cochlear Implantation and Social Outcomes

NCT07584837
View directory record Official record
Conditions
Hearing Loss, Bilateral Sensorineural
Interventions
Cochlear implant
Procedure
Lead sponsor
University of Southern California
Other
Eligibility
60 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2030
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Oct 22, 2026, 4:27 AM EDT
Completed Phase 4 Interventional Results available

Bilateral Benefit in Adult Users of the HiRes 90K Bionic Ear System

NCT00205881
View directory record Official record
Conditions
Hearing Loss
Interventions
HiRes 90K Bionic Ear System
Device
Lead sponsor
Advanced Bionics
Industry
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
9
States / cities
Los Angeles, California • Palo Alto, California • Miami, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Mar 1, 2012 · Synced Oct 22, 2026, 4:27 AM EDT
Terminated Not applicable Interventional Results available

Efficacy of a Coupler-based Fitting Approach for Experienced Users Receiving Replacement Hearing Aids

NCT03569228
View directory record Official record
Conditions
Hearing Loss
Interventions
Study 1 - ITE hearing aids, Study 1 - BTE hearing aids, Study 3 (open-fit comparison), Study 3 (closed-fit comparison), Study 3 (experimental open-fit), Study 3 (experimental closed-fit)
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 85 Years
Enrollment
163 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 25, 2025 · Synced Oct 22, 2026, 4:27 AM EDT
Completed Not applicable Interventional

Adaptation and Pilot Testing of a Behavioral Parent Training Program for Parents of Deaf and Hard of Hearing Children

NCT03483428
View directory record Official record
Conditions
Hearing Loss, Behavior Disorders, Parenting
Interventions
Interventionist training and supervision, Behavioral parent training
Behavioral
Lead sponsor
University of Kentucky
Other
Eligibility
2 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Apr 17, 2019 · Synced Oct 22, 2026, 4:27 AM EDT
Not listed Not applicable Interventional

Evaluation of Hearing Protection Fit Testing Program

NCT02109757
View directory record Official record
Conditions
Hearing Loss
Interventions
Software intervention and education, Education only
Other
Lead sponsor
United States Air Force
Federal
Eligibility
Not listed
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2014
U.S. locations
2
States / cities
Elemendorf Air Force Base, Alaska • Dayton, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 10, 2014 · Synced Oct 22, 2026, 4:27 AM EDT
Active, not recruiting Phase 4 Interventional

Repurposed Use of Allergic Rhinitis and Allergic Asthma Drug to Reduce Vertigo and Hearing Loss in Meniere's Disease

NCT04815187
View directory record Official record
Conditions
Meniere Disease, Allergic Rhinitis, Vertigo
Interventions
Montelukast, Placebo
Drug
Lead sponsor
House Ear Institute
Other
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
2
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 18, 2025 · Synced Oct 22, 2026, 4:27 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Study to Evaluate the Safety and Pharmacokinetics of SPI-1005

NCT01452607
View directory record Official record
Conditions
Hearing Loss, Cancer
Interventions
SPI-1005, Placebo
Drug
Lead sponsor
Sound Pharmaceuticals, Incorporated
Industry
Eligibility
19 Years to 50 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006
U.S. locations
1
States / cities
Lincoln, Nebraska
Source: ClinicalTrials.gov public record
Updated Jun 29, 2016 · Synced Oct 22, 2026, 4:27 AM EDT
Active, not recruiting Not applicable Interventional

A Pivotal Study to Evaluate the Clinical Benefit, Performance and Safety of a Totally Implantable Cochlear Implant (TICI) System in Adults

NCT07287124
View directory record Official record
Conditions
Hearing Loss, Bilateral Sensorineural
Interventions
Cochlear implant
Device
Lead sponsor
Cochlear
Industry
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
11
States / cities
Englewood, Colorado • Miami, Florida • Iowa City, Iowa + 8 more
Source: ClinicalTrials.gov public record
Updated Oct 1, 2026 · Synced Oct 22, 2026, 4:27 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Evaluation of Revised Indicatons (ERID) for Cochlear Implant Candidacy for the Adult CMS Population

NCT02075229
View directory record Official record
Conditions
Bilateral Sensorineural Hearing Loss
Interventions
Cochlear implant
Device
Lead sponsor
American Cochlear Implant Alliance
Other
Eligibility
65 Years and older
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
19
States / cities
Los Angeles, California • Englewood, Colorado • Miami, Florida + 16 more
Source: ClinicalTrials.gov public record
Updated Jul 27, 2021 · Synced Oct 22, 2026, 4:27 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Evaluation of Flexible Conductive Hearing Aids

NCT07222202
View directory record Official record
Conditions
Conductive Hearing Loss
Interventions
flexible conductive hearing aid
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
6 Months to 80 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 22, 2026, 4:27 AM EDT
Completed Not applicable Interventional Results available

In Field Performance of a Hearing Aid Transducer

NCT04787055
View directory record Official record
Conditions
Hearing Loss
Interventions
Receiver-in-canal hearing instrument
Device
Lead sponsor
Sonova AG
Industry
Eligibility
18 Years to 99 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Aurora, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 21, 2023 · Synced Oct 22, 2026, 4:27 AM EDT
Recruiting Not applicable Interventional

Speech Understanding and Listening Effort Benefits of Hearing Instruments

NCT07116135
View directory record Official record
Conditions
Hearing Loss, Bilateral
Interventions
hearing instruments
Device
Lead sponsor
Sonova AG
Industry
Eligibility
18 Years to 95 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Aug 11, 2025 · Synced Oct 22, 2026, 4:27 AM EDT
Completed No phase listed Observational

Natural History and Genetic Studies of Usher Syndrome

NCT00106743
View directory record Official record
Conditions
Retinitis Pigmentosa Syndromic, Congenital Deafness, Usher Syndrome, Retinitis Pigmentosa and Deafness, Retinitis Pigmentosa
Interventions
Not listed
Lead sponsor
National Eye Institute (NEI)
NIH
Eligibility
2 Years and older
Enrollment
249 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2019
U.S. locations
2
States / cities
Bethesda, Maryland • New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 12, 2019 · Synced Oct 22, 2026, 4:27 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Effectiveness of Hearing-aid Based Wind-noise Algorithm

NCT00738244
View directory record Official record
Conditions
Hearing Impairment
Interventions
Not listed
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Sep 26, 2011 · Synced Oct 22, 2026, 4:27 AM EDT
Completed Phase 2 Interventional

Comparison of Single Versus Repeat Doses of AM-101 in the Treatment of Acute Inner Ear Tinnitus

NCT01270282
View directory record Official record
Conditions
Tinnitus
Interventions
AM-101 0.81 mg/mL, Placebo
Drug
Lead sponsor
Auris Medical, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
5
States / cities
Gainsville, Florida • Kansas City, Kansas • Louisville, Kentucky + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 26, 2015 · Synced Oct 22, 2026, 4:27 AM EDT