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ClinicalTrials.gov public records Last synced Oct 23, 2026, 8:36 AM EDT

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Showing 433–456 of 529 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Hearing Disorders and Deafness Clear all
Recruiting Not applicable Interventional

Characterizing Variability in Hearing Aid Outcomes in Among Older Adults With Alzheimer's Dementia

NCT04240561
View directory record Official record
Conditions
Hearing Loss, Sensorineural, Dementia of Alzheimer Type, Amnestic Mild Cognitive Impairment
Interventions
High level of signal manipulation, Low level of signal manipulation
Device
Lead sponsor
Northwestern University
Other
Eligibility
50 Years to 90 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
2
States / cities
Chicago, Illinois • Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Oct 23, 2026, 8:36 AM EDT
Completed Not applicable Interventional Results available

North Carolina Genomic Evaluation by Next-generation Exome Sequencing, 2

NCT03548779
View directory record Official record
Conditions
Epilepsy; Seizure, Neuromuscular Diseases, Brain Malformation, Intellectual Disability, Autism Spectrum Disorder, Hypotonia, Inborn Errors of Metabolism, Movement Disorders, Genetic Disease, Development Delay, Chromosome Abnormality, Hearing Loss, Dysmorphic Features, Skeletal Dysplasia, Congenital Abnormality, Microcephaly, Macrocephaly
Interventions
Pre-visit prep, usual care + exome seq
Behavioral · Diagnostic Test
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
0 Years and older
Enrollment
548 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
3
States / cities
Asheville, North Carolina • Chapel Hill, North Carolina • Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated May 13, 2025 · Synced Oct 23, 2026, 8:36 AM EDT
Completed Not applicable Interventional

Hearing Aid Education and Adaptation System

NCT02839759
View directory record Official record
Conditions
Hearing Loss
Interventions
TELLYHealth
Other
Lead sponsor
Healthcare Technologies and Methods, LLC
Industry
Eligibility
50 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
2
States / cities
Gainesville, Florida • Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated May 14, 2020 · Synced Oct 23, 2026, 8:36 AM EDT
Completed Phase 1Phase 2 Interventional Results available

A Clinical Trial of Anakinra for Steroid-Resistant Autoimmune Inner Ear Disease

NCT01267994
View directory record Official record
Conditions
Sensorineural Hearing Loss, Autoimmune Inner Ear Disease
Interventions
Anakinra
Drug
Lead sponsor
Andrea Vambutas
Other
Eligibility
13 Years to 75 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
New Hyde Park, New York
Source: ClinicalTrials.gov public record
Updated Jan 10, 2018 · Synced Oct 23, 2026, 8:36 AM EDT
Not listed Not applicable Interventional

Hear Me Read 2021 Clinical Trial

NCT05245799
View directory record Official record
Conditions
Hearing Loss, Deafness, Hearing Disorders in Children, Hearing Impaired Children, Speech Therapy, Speech Disorders in Children, Literacy
Interventions
Speech Language Therapy, Digital Software Application
Behavioral
Lead sponsor
Prasanth Pattisapu
Other
Eligibility
3 Years to 5 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 30, 2023 · Synced Oct 23, 2026, 8:36 AM EDT
Not yet recruiting Phase 1Phase 2 Interventional

A Basket Clinical Study to Assess Glycerol Tributyrate in Patients With Mitochondrial Encephalopathy, Lactic Acidosis, Stroke-like Episodes (MELAS) or Leber's Hereditary Optic Neuropathy-Plus (LHON-Plus)

NCT06792500
View directory record Official record
Conditions
MELAS Syndrome, Lebers Hereditory Optic Neuropathy With Extra Ocular Symptoms (LHON-Plus)
Interventions
Glycerol Tributyrate
Drug
Lead sponsor
George Washington University
Other
Eligibility
18 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 23, 2026, 8:36 AM EDT
Terminated Phase 1 Interventional

First in Human Safety Study of FX-345 in Adults With Sensorineural Hearing Loss

NCT05664100
View directory record Official record
Conditions
Hearing Loss, Sensorineural
Interventions
FX-345, Placebo
Drug
Lead sponsor
Frequency Therapeutics
Industry
Eligibility
18 Years to 67 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
4
States / cities
Sarasota, Florida • Spartanburg, South Carolina • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Apr 27, 2023 · Synced Oct 23, 2026, 8:36 AM EDT
Completed No phase listed Interventional Results available

Evaluation of Remote Fitting in Adult and Pediatric Users of the HiResolution Bionic Ear System

NCT05034731
View directory record Official record
Conditions
Hearing Loss, Ear Diseases, Hearing Disorders, Otolaryngological Disease
Interventions
Remote Fitting, In-Office Fitting
Device
Lead sponsor
Advanced Bionics
Industry
Eligibility
13 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 21, 2023 · Synced Oct 23, 2026, 8:36 AM EDT
Recruiting No phase listed Observational

Long-term Follow-up of a Cochlear Implant With Dexamethasone Eluting Electrode Array

NCT06936449
View directory record Official record
Conditions
Sensorineural Hearing Loss, Bilateral Hearing Loss
Interventions
CI632D, CI632
Device
Lead sponsor
Cochlear
Industry
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
3
States / cities
Englewood, Colorado • Iowa City, Iowa • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Oct 23, 2026, 8:36 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Comparing Hearing Aid Fitting Methods in Blast-exposed Veterans

NCT06309264
View directory record Official record
Conditions
Auditory Diseases, Central
Interventions
Phonak Lumina P90
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 60 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
3
States / cities
Loma Linda, California • Sepulveda, California • West Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Oct 23, 2026, 8:36 AM EDT
Completed No phase listed Observational

Effects of Stimulus Validity on Speech Recognition

NCT00013364
View directory record Official record
Conditions
Hearing Impaired
Interventions
Talker variability
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 85 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2001
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 21, 2009 · Synced Oct 23, 2026, 8:36 AM EDT
Completed Not applicable Interventional Results available

The EarLens System Long Term Safety and Efficacy Definitive Multi-Center Study

NCT02042404
View directory record Official record
Conditions
Hearing Impairment
Interventions
Sound amplification provided via EarLens System.
Device
Lead sponsor
EarLens Corporation
Industry
Eligibility
18 Years to 85 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
3
States / cities
Menlo Park, California • San Jose, California • Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Feb 2, 2016 · Synced Oct 23, 2026, 8:36 AM EDT
Completed Not applicable Interventional

Head and Neck Cancer Survivorship Ototoxicity Screening (SOS)

NCT05789316
View directory record Official record
Conditions
Head and Neck Cancer Survivors, Cancer of the Head and Neck Surviors
Interventions
Ototoxicity Screening Protocol
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 12, 2026 · Synced Oct 23, 2026, 8:36 AM EDT
Completed No phase listed Observational Results available

Littlears Auditory Questionnaire: Validation Study in CI Children

NCT00785707
View directory record Official record
Conditions
Hearing Loss
Interventions
Not listed
Lead sponsor
Med-El Corporation
Industry
Eligibility
Up to 24 Months
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
5
States / cities
Augusta, Georgia • Durham, North Carolina • Nashville, Tennessee + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 26, 2017 · Synced Oct 23, 2026, 8:36 AM EDT
Terminated Phase 2 Interventional Results available

Randomized Controlled Trial of Valganciclovir for Cytomegalovirus Infected Hearing Impaired Infants

NCT03107871
View directory record Official record
Conditions
Cmv Congenital, CMV, Congenital Cmv, SNHL, Sensorineural Hearing Loss
Interventions
Valganciclovir, Simple Syrup
Drug
Lead sponsor
Albert Park
Other
Eligibility
1 Month to 12 Months
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
30
States / cities
Palo Alto, California • San Diego, California • San Francisco, California + 25 more
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Oct 23, 2026, 8:36 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Cochlear Implantation in Children With Asymmetric Hearing Loss or Single-Sided Deafness Clinical Trial

NCT04793412
View directory record Official record
Conditions
Asymmetric Hearing Loss, Single-sided Deafness, Unilateral Deafness
Interventions
Cochlear Implant
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
4 Years to 14 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
5
States / cities
Los Angeles, California • Minneapolis, Minnesota • St Louis, Missouri + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Oct 23, 2026, 8:36 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Perceptual Consequences of Cochlear Implant Electrode-neuron Interfaces

NCT05867173
View directory record Official record
Conditions
Deafness
Interventions
Experimental Speech Processing Strategy
Other
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
3 Months and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
2
States / cities
Boston, Massachusetts • Waltham, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 26, 2025 · Synced Oct 23, 2026, 8:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

ACEMg Hearing Preservation, Tinnitus and Hyperacusis Relief

NCT06477354
View directory record Official record
Conditions
Sensorineural Hearing Loss, Tinnitus, SNHL, Inner Ear Hearing Loss
Interventions
ACEMg
Dietary Supplement
Lead sponsor
Keep Hearing, Inc.
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 31, 2025 · Synced Oct 23, 2026, 8:36 AM EDT
Completed Not applicable Interventional

A Comparison of Hearing Aid Noise Programs on Speech Intelligibility

NCT06957730
View directory record Official record
Conditions
Hearing Loss, Bilateral or Unilateral
Interventions
Phonak Audeo Infinio Hearing Aid
Device
Lead sponsor
Sonova AG
Industry
Eligibility
18 Years to 95 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Aurora, Illinois
Source: ClinicalTrials.gov public record
Updated May 30, 2025 · Synced Oct 23, 2026, 8:36 AM EDT
Completed Not applicable Interventional Results available

Clinical Evaluation of a Cochlear Implant Sound Processor

NCT04237207
View directory record Official record
Conditions
Hearing Loss, Ear Diseases, Hearing Disorders, Otorhinolaryngologic Diseases
Interventions
Naída Cochlear Implant Q90 sound processor (Naida CI Q90) & software, 301-M062 sound processor & software
Device
Lead sponsor
Advanced Bionics
Industry
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
6
States / cities
Aurora, Colorado • Tampa, Florida • Kansas City, Missouri + 3 more
Source: ClinicalTrials.gov public record
Updated May 13, 2022 · Synced Oct 23, 2026, 8:36 AM EDT
Completed Not applicable Interventional Results available

Evaluation of the Clinical Benefit of the Hearing Aids Tinnitus Feature.

NCT05292534
View directory record Official record
Conditions
Hearing Loss, Sensorineural, Tinnitus
Interventions
hearing aid amplification, hearing aid amplification with an added sound
Device
Lead sponsor
Sonova AG
Industry
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Jul 5, 2024 · Synced Oct 23, 2026, 8:36 AM EDT
Active, not recruiting Phase 2 Interventional

AMX0035 in Adult Patients With Wolfram Syndrome

NCT05676034
View directory record Official record
Conditions
Wolfram Syndrome
Interventions
AMX0035
Drug
Lead sponsor
Amylyx Pharmaceuticals Inc.
Industry
Eligibility
17 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Oct 23, 2026, 8:36 AM EDT
Terminated Phase 1Phase 2 Interventional Results available

Study of the Effects of Anakinra in Corticosteroid-resistant Subjects With Sudden Sensorineural Hearing Loss

NCT02414152
View directory record Official record
Conditions
Hearing Loss, Sudden
Interventions
anakinra
Drug
Lead sponsor
Andrea Vambutas
Other
Eligibility
18 Years to 75 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
New Hyde Park, New York
Source: ClinicalTrials.gov public record
Updated Mar 13, 2017 · Synced Oct 23, 2026, 8:36 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Auditory Training and Hearing Aid Satisfaction

NCT04230876
View directory record Official record
Conditions
Hearing Impairment, Sensorineural
Interventions
Auditory Brian Training Games/Activities
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
60 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 19, 2022 · Synced Oct 23, 2026, 8:36 AM EDT