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ClinicalTrials.gov public records Last synced Oct 21, 2026, 8:24 AM EDT

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Showing 169–192 of 529 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Hearing Disorders and Deafness Clear all
Completed Phase 1Phase 2 Interventional

OTO-413 in Subjects With Speech-in-Noise Hearing Impairment

NCT04129775
View directory record Official record
Conditions
Sensorineural Hearing Loss
Interventions
OTO-413, Placebo
Drug
Lead sponsor
Otonomy, Inc.
Industry
Eligibility
21 Years to 64 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
8
States / cities
Colorado Springs, Colorado • Hollywood, Florida • Miami, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Oct 27, 2022 · Synced Oct 21, 2026, 8:24 AM EDT
Completed Not applicable Interventional

CROS Application in CI

NCT03243097
View directory record Official record
Conditions
Hearing Loss
Interventions
Phase I - Standard Microphone Cros Input, Phase II - Automatic directional microphone Cros Input, Phase III - No Cros Input
Device
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Apr 27, 2023 · Synced Oct 21, 2026, 8:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Application of Ideal Binary Masking to Disordered Speech

NCT05244603
View directory record Official record
Conditions
Hearing Loss, Sensorineural, Dysarthria
Interventions
Ideal binary mask
Behavioral
Lead sponsor
Utah State University
Other
Eligibility
18 Years to 90 Years
Enrollment
435 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Logan, Utah
Source: ClinicalTrials.gov public record
Updated Mar 26, 2025 · Synced Oct 21, 2026, 8:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Sound Quality Comparisons With Different Hearing Aid Couplings and Venting Systems

NCT05180630
View directory record Official record
Conditions
Hearing Loss, Sensorineural
Interventions
Audeo P90 hearing aid with custom earmolds using dynamic venting, Audeo P90 hearing aid with Open domes, Audeo P90 hearing aid with Vented domes
Device
Lead sponsor
Sonova AG
Industry
Eligibility
18 Years to 80 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Aurora, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 28, 2023 · Synced Oct 21, 2026, 8:24 AM EDT
Active, not recruiting Phase 2 Interventional

A Study to Determine the Long-Term Safety, Tolerability and Biological Activity of SAR421869 in Patients With Usher Syndrome Type 1B

NCT02065011
View directory record Official record
Conditions
Usher's Syndrome
Interventions
Blood draw for the laboratory assessment
Drug
Lead sponsor
Sanofi
Industry
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2031
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced Oct 21, 2026, 8:24 AM EDT
Completed Not applicable Interventional Results available

Variability In Hearing Aid Outcomes In Older Adults

NCT02448706
View directory record Official record
Conditions
Hearing Loss, Presbycusis
Interventions
Hearing Aid Fitting A, Hearing Aid Fitting B
Device
Lead sponsor
Northwestern University
Other
Eligibility
54 Years and older
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 17, 2020 · Synced Oct 21, 2026, 8:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Remote Microphone Candidacy Study

NCT03897634
View directory record Official record
Conditions
Hearing Loss, Sensorineural
Interventions
Remote Microphone
Device
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 85 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 10, 2021 · Synced Oct 21, 2026, 8:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Test of a Web-based Intervention to Promote Hearing Protector Use

NCT01454895
View directory record Official record
Conditions
Noise-induced Hearing Loss
Interventions
Sampler of hearing protection devices, Static Web-based information, Interactive Web-based information
Behavioral
Lead sponsor
Marjorie McCullagh
Other
Eligibility
18 Years and older
Enrollment
498 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 5, 2015 · Synced Oct 21, 2026, 8:24 AM EDT
Enrolling by invitation No phase listed Observational

Long Term Follow-up Study of AAVAnc80-hOTOF Gene Therapy

NCT06696456
View directory record Official record
Conditions
Otoferlin Gene-mediated Hearing Loss
Interventions
Not listed
Lead sponsor
Akouos, Inc.
Industry
Eligibility
Not listed
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2033
U.S. locations
3
States / cities
Iowa City, Iowa • Boston, Massachusetts • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Oct 21, 2026, 8:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Randomized Trial Comparison of Ototoxicity Monitoring Programs

NCT02099786
View directory record Official record
Conditions
Cisplatin Ototoxicity, Hearing Loss
Interventions
COMP-VA, Standard of care
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 85 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 9, 2019 · Synced Oct 21, 2026, 8:24 AM EDT
Completed Not applicable Interventional Results available

Cochlear Implantation in Adults With Asymmetric Hearing Loss Clinical Trial

NCT03052920
View directory record Official record
Conditions
Hearing Loss
Interventions
Cochlear implant
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
4
States / cities
Los Angeles, California • Kansas City, Missouri • St Louis, Missouri + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Oct 21, 2026, 8:24 AM EDT
Terminated Not applicable Interventional Results available

Implantation With the Nucleus CI532 Cochlear Implant in Adults

NCT02677220
View directory record Official record
Conditions
Hearing Loss
Interventions
CI532 cochlear implant
Device
Lead sponsor
Cochlear
Industry
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 12, 2019 · Synced Oct 21, 2026, 8:24 AM EDT
Completed Not applicable Interventional

Aural Rehabilitation for Cochlear Implant Users Via Telerehab Technology

NCT03157492
View directory record Official record
Conditions
Hearing Loss, Deafness
Interventions
Aural Rehabilitation Group, Cognitive Training Group
Behavioral
Lead sponsor
Gallaudet University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
5
States / cities
Washington D.C., District of Columbia • Tampa, Florida • College Park, Maryland + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 14, 2021 · Synced Oct 21, 2026, 8:24 AM EDT
Completed No phase listed Observational Results available

I-Tracking Neurodegeneration in Early Wolfram Syndrome

NCT03951298
View directory record Official record
Conditions
Wolfram Syndrome
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
1 Day and older
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 23, 2026 · Synced Oct 21, 2026, 8:24 AM EDT
Completed Not applicable Interventional Results available

Osia CPT Code Study

NCT04320407
View directory record Official record
Conditions
Conductive Hearing Loss, Mixed Hearing Loss
Interventions
Osia 2 System
Device
Lead sponsor
Cochlear
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
4
States / cities
Phoenix, Arizona • Tucson, Arizona • Ann Arbor, Michigan + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 25, 2022 · Synced Oct 21, 2026, 8:24 AM EDT
Completed No phase listed Observational

Study of Usher Syndromes, Type 1 and Type 2

NCT00001347
View directory record Official record
Conditions
Retinitis Pigmentosa
Interventions
Not listed
Lead sponsor
National Eye Institute (NEI)
NIH
Eligibility
Not listed
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1993 – 2002
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 21, 2026, 8:24 AM EDT
Terminated No phase listed Observational

Genetic Analysis of Human Hereditary Hearing Impairment

NCT00001606
View directory record Official record
Conditions
Partial Hearing Loss
Interventions
Not listed
Lead sponsor
National Institute on Deafness and Other Communication Disorders (NIDCD)
NIH
Eligibility
Not listed
Enrollment
404 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 2015
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 17, 2019 · Synced Oct 21, 2026, 8:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Iowa/Nucleus 10/10 mm and Nucleus Freedom Feasibility Study

NCT00594061
View directory record Official record
Conditions
Hearing Loss, Sensorineural, Hearing Loss, Bilateral
Interventions
Iowa/Nucleus 10/10 mm and Freedom Cochlear Implantation
Device
Lead sponsor
Bruce J Gantz
Other
Eligibility
12 Months to 24 Months
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2016
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 23, 2018 · Synced Oct 21, 2026, 8:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Hearing Aid Noise Reduction in Pediatric Users Pilot Study (Oticon Pilot Study)

NCT04469946
View directory record Official record
Conditions
Hearing Impairment, Sensorineural Hearing Loss, Bilateral
Interventions
Oticon OpenSound Navigator speech enhancement algorithm
Device
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
6 Years to 12 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 14, 2020 · Synced Oct 21, 2026, 8:24 AM EDT
Completed Not applicable Interventional Results available

Esteem Totally Implantable Hearing System

NCT01092910
View directory record Official record
Conditions
Mild to Severe Sensorineural Hearing Loss
Interventions
Esteem Totally Implantable Hearing System
Device
Lead sponsor
Envoy Medical Corporation
Industry
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
5
States / cities
Newport Beach, California • Burlington, Massachusetts • Greensboro, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 2, 2020 · Synced Oct 21, 2026, 8:24 AM EDT
Completed Not applicable Interventional

Speech Perception for Children With Cochlear Implants

NCT01059838
View directory record Official record
Conditions
Hearing Loss
Interventions
sentence recognition
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
4 Years to 17 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 8, 2017 · Synced Oct 21, 2026, 8:24 AM EDT
Completed No phase listed Interventional Results available

Evaluation of Remote Fitting in Adult and Pediatric Users of the HiResolution Bionic Ear System

NCT05034731
View directory record Official record
Conditions
Hearing Loss, Ear Diseases, Hearing Disorders, Otolaryngological Disease
Interventions
Remote Fitting, In-Office Fitting
Device
Lead sponsor
Advanced Bionics
Industry
Eligibility
13 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 21, 2023 · Synced Oct 21, 2026, 8:24 AM EDT
Recruiting Not applicable Interventional

AI Noise Reduction in Phonak Hearing Aids

NCT06743295
View directory record Official record
Conditions
Hearing Loss
Interventions
DEEPSONIC™ Deep Sound Optimized Neural Integrated Chip Artificial intelligence-based noise reduction
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 110 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 6, 2026 · Synced Oct 21, 2026, 8:24 AM EDT
Completed Phase 2 Interventional Results available

Valganciclovir Therapy in Infants and Children With Congenital CMV Infection and Hearing Loss

NCT01649869
View directory record Official record
Conditions
Cytomegalovirus Infection
Interventions
Placebo, Valganciclovir
Other · Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
1 Month to 4 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
9
States / cities
Birmingham, Alabama • Washington D.C., District of Columbia • St Louis, Missouri + 6 more
Source: ClinicalTrials.gov public record
Updated Oct 16, 2024 · Synced Oct 21, 2026, 8:24 AM EDT