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Showing 1–24 of 223 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Hearing Loss, Sensorineural Clear all
Active, not recruiting Phase 2 Interventional

Randomized Controlled Trial of Valganciclovir for Cytomegalovirus Infected Hearing Impaired Infants

NCT03107871
View directory record Official record
Conditions
Cmv Congenital, CMV, Congenital Cmv, SNHL, Sensorineural Hearing Loss
Interventions
Valganciclovir, Simple Syrup
Drug
Lead sponsor
Albert Park
Other
Eligibility
1 Month to 12 Months
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
30
States / cities
Palo Alto, California • San Diego, California • San Francisco, California + 25 more
Source: ClinicalTrials.gov public record
Updated Feb 23, 2022 · Synced Jun 25, 2026, 6:50 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Evaluation of Revised Indicatons (ERID) for Cochlear Implant Candidacy for the Adult CMS Population

NCT02075229
View directory record Official record
Conditions
Bilateral Sensorineural Hearing Loss
Interventions
Cochlear implant
Device
Lead sponsor
American Cochlear Implant Alliance
Other
Eligibility
65 Years and older
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
19
States / cities
Los Angeles, California • Englewood, Colorado • Miami, Florida + 16 more
Source: ClinicalTrials.gov public record
Updated Jul 26, 2021 · Synced Jun 25, 2026, 6:50 PM EDT
Completed Phase 1Phase 2 Interventional

Study to Evaluate Safety and Tolerability of QR-421a in Subjects With RP Due to Mutations in Exon 13 of the USH2A Gene

NCT03780257
View directory record Official record
Conditions
Retinitis Pigmentosa, Usher Syndrome Type 2, Deaf Blind, Retinal Disease, Eye Diseases, Eye Diseases, Hereditary, Eye Disorders Congenital, Vision Disorders
Interventions
QR-421a, Sham-procedure (dose cohort 1&2 only)
Drug · Other
Lead sponsor
ProQR Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
4
States / cities
Boston, Massachusetts • Ann Arbor, Michigan • Portland, Oregon + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 19, 2022 · Synced Jun 25, 2026, 6:50 PM EDT
Completed Not applicable Interventional Results available

Evaluation of the Nucleus Hybrid™ L24 Cochlear Implant System

NCT00678899
View directory record Official record
Conditions
Sensorineural Hearing Loss
Interventions
Nucleus Hybrid L24
Device
Lead sponsor
Cochlear
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 14, 2015 · Synced Jun 25, 2026, 6:50 PM EDT
Completed Not applicable Interventional Results available

Hybrid L24 New Enrollment Post Approval Study

NCT02379819
View directory record Official record
Conditions
High Frequency Sensorineural Hearing Loss
Interventions
Nucleus Hybrid L24 Implant
Device
Lead sponsor
Cochlear
Industry
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
19
States / cities
Phoenix, Arizona • Sacramento, California • Aurora, Colorado + 15 more
Source: ClinicalTrials.gov public record
Updated Mar 12, 2023 · Synced Jun 25, 2026, 6:50 PM EDT
Terminated Phase 2Phase 3 Interventional Results available

Study to Evaluate the Efficacy Safety and Tolerability of Ultevursen in Subjects With RP Due to Mutations in Exon 13 of the USH2A Gene (Sirius)

NCT05158296
View directory record Official record
Conditions
Retinitis Pigmentosa, Usher Syndrome Type 2, Deaf Blind, Retinal Disease, Eye Diseases, Eye Diseases, Hereditary, Eye Disorders Congenital, Vision Disorders
Interventions
Ultevursen, Sham-procedure
Drug · Other
Lead sponsor
Laboratoires Thea
Industry
Eligibility
12 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
10
States / cities
San Diego, California • San Francisco, California • Miami, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Jul 11, 2024 · Synced Jun 25, 2026, 6:50 PM EDT
Recruiting Not applicable Interventional

Characterizing Variability in Hearing Aid Outcomes in Among Older Adults With Alzheimer's Dementia

NCT04240561
View directory record Official record
Conditions
Hearing Loss, Sensorineural, Dementia of Alzheimer Type, Amnestic Mild Cognitive Impairment
Interventions
High level of signal manipulation, Low level of signal manipulation
Device
Lead sponsor
Northwestern University
Other
Eligibility
50 Years to 90 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
2
States / cities
Chicago, Illinois • Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Jun 25, 2026, 6:50 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Appreciation for Music Processed by Hearing Aids

NCT05568329
View directory record Official record
Conditions
Sensorineural Hearing Loss
Interventions
Hearing Aid Program
Device
Lead sponsor
Purdue University
Other
Eligibility
18 Years to 25 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 28, 2023 · Synced Jun 25, 2026, 6:50 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Neural Changes in the Aging Auditory System

NCT00264407
View directory record Official record
Conditions
Progesterone, Estrogens, Hearing, Psychoacoustics, Auditory Perceptual Disorders
Interventions
Hormone Replacement Therapy - HRT
Drug
Lead sponsor
University of Rochester
Other
Eligibility
60 Years to 86 Years · Female only
Enrollment
126 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2005
U.S. locations
2
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Dec 11, 2005 · Synced Jun 25, 2026, 6:50 PM EDT
Completed Not applicable Interventional Results available

Variability In Hearing Aid Outcomes In Older Adults

NCT02448706
View directory record Official record
Conditions
Hearing Loss, Presbycusis
Interventions
Hearing Aid Fitting A, Hearing Aid Fitting B
Device
Lead sponsor
Northwestern University
Other
Eligibility
54 Years and older
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 16, 2020 · Synced Jun 25, 2026, 6:50 PM EDT
Not listed Early Phase 1 Interventional

Comparing Topical Tetracaine Drops to Topical Focal Phenol for Local Anesthesia During Intratympanic Steroid Injection

NCT04794842
View directory record Official record
Conditions
Intratympanic Steroid Injection, Idiopathic Sudden Sensorineural Hearing Loss, Meniere Disease
Interventions
Tetracaine 5% drops, Phenol 90% concentration
Drug
Lead sponsor
Our Lady of the Lake Hospital
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Oct 30, 2023 · Synced Jun 25, 2026, 6:50 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

The Contributions of Age Related Changes in the Sound Localization Pathway to Central Hearing Loss

NCT04513782
View directory record Official record
Conditions
Healthy Individuals, Hearing Loss, Central
Interventions
Audiological Assessments
Diagnostic Test
Lead sponsor
University of Colorado, Denver
Other
Eligibility
40 Years to 89 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Jun 25, 2026, 6:50 PM EDT
Active, not recruiting Early Phase 1 Interventional

Effect of Donepezil on Speech Recognition in Cochlear Implant Users

NCT05438264
View directory record Official record
Conditions
Bilateral Sensorineural Hearing Loss
Interventions
Donepezil, Placebo
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 100 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 1, 2025 · Synced Jun 25, 2026, 6:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Iowa/Nucleus 10/10 mm and Nucleus Freedom Feasibility Study

NCT00594061
View directory record Official record
Conditions
Hearing Loss, Sensorineural, Hearing Loss, Bilateral
Interventions
Iowa/Nucleus 10/10 mm and Freedom Cochlear Implantation
Device
Lead sponsor
Bruce J Gantz
Other
Eligibility
12 Months to 24 Months
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2016
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 22, 2018 · Synced Jun 25, 2026, 6:50 PM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers Results available

Noise-Induced Hearing Loss-Acute Exposure Treatment (UA)

NCT04774250
View directory record Official record
Conditions
Hearing Loss, Noise-Induced
Interventions
Zonisamide 100Mg Cap, Placebo
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Akron, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Jun 25, 2026, 6:50 PM EDT
Terminated Phase 1Phase 2 Interventional Results available

Study of the Effects of Anakinra in Corticosteroid-resistant Subjects With Sudden Sensorineural Hearing Loss

NCT02414152
View directory record Official record
Conditions
Hearing Loss, Sudden
Interventions
anakinra
Drug
Lead sponsor
Andrea Vambutas
Other
Eligibility
18 Years to 75 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
New Hyde Park, New York
Source: ClinicalTrials.gov public record
Updated Mar 12, 2017 · Synced Jun 25, 2026, 6:50 PM EDT
Completed Phase 1 Interventional

FX-322 in Adults With Severe Sensorineural Hearing Loss

NCT04629664
View directory record Official record
Conditions
Hearing Loss, Sensorineural, Noise Induced Hearing Loss, Sudden Hearing Loss
Interventions
FX-322, Placebo
Drug · Other
Lead sponsor
Frequency Therapeutics
Industry
Eligibility
18 Years to 65 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
7
States / cities
Novi, Michigan • Omaha, Nebraska • Amherst, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 31, 2022 · Synced Jun 25, 2026, 6:50 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Self-efficacy-based Auditory Rehabilitation With Over-the-Counter Hearing Aids

NCT06560918
View directory record Official record
Conditions
Hearing Loss, Sensorineural
Interventions
hearing aids
Device
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years to 85 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Dec 23, 2025 · Synced Jun 25, 2026, 6:50 PM EDT
Completed Not applicable Interventional Results available

Osia CPT Code Study

NCT04320407
View directory record Official record
Conditions
Conductive Hearing Loss, Mixed Hearing Loss
Interventions
Osia 2 System
Device
Lead sponsor
Cochlear
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
4
States / cities
Phoenix, Arizona • Tucson, Arizona • Ann Arbor, Michigan + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 24, 2022 · Synced Jun 25, 2026, 6:50 PM EDT
Withdrawn Phase 2 Interventional Accepts healthy volunteers

A Phase 2b Study of SPI-1005 to Prevent Acute Noise Induced Hearing Loss

NCT02779192
View directory record Official record
Conditions
Noise Induced Hearing Loss
Interventions
SPI-1005 200mg, SPI-1005 400mg, Placebo
Drug
Lead sponsor
Sound Pharmaceuticals, Incorporated
Industry
Eligibility
18 Years to 50 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
5
States / cities
Miami, Florida • Kansas City, Kansas • Charleston, South Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Jun 25, 2026, 6:50 PM EDT
Not yet recruiting Not applicable Interventional

Microtable® Method for Cochlear Implantation Investigational Device Exemption (IDE)

NCT03101917
View directory record Official record
Conditions
Hearing Loss, Cochlear
Interventions
The Microtable® Stereotactic System
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
22 Years to 80 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Jun 25, 2026, 6:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Performance of a New Implant System for Bone Conduction Hearing

NCT03086135
View directory record Official record
Conditions
Deafness; Sensoneural Single Sided, Conductive Hearing Loss, Mixed Hearing Loss
Interventions
Osia System
Device
Lead sponsor
Cochlear
Industry
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 13, 2021 · Synced Jun 25, 2026, 6:50 PM EDT
Completed Not applicable Interventional Results available

Benefits of Bimodal Streaming With MED-EL Cochlear Implants and Starkey Hearing Aids

NCT07028619
View directory record Official record
Conditions
Hearing Loss, Sensorineural, Sensorineural Hearing Loss, Bilateral, Cochlear Implant Recipients, Asymmetric Hearing Loss
Interventions
Bimodal Streaming Configuration
Device
Lead sponsor
Med-El Corporation
Industry
Eligibility
Not listed
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Meridian, Idaho
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Jun 25, 2026, 6:50 PM EDT
Not yet recruiting Not applicable Interventional

Maximizing Quality of Life After Cancer Through Rehabilitation

NCT07622407
View directory record Official record
Conditions
Head and Neck Cancer, Hearing Loss, Tinnitus, Dysphagia
Interventions
TIMELY REHAB
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 89 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2030
U.S. locations
3
States / cities
Durham, North Carolina • Portland, Oregon • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Jun 25, 2026, 6:50 PM EDT