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Showing 1–24 of 124 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Heart Assist Device Clear all
Terminated Phase 4 Interventional Results available

Nesiritide and Renal Function After the Total Artificial Heart

NCT01836809
View directory record Official record
Conditions
Congestive Heart Failure, Cardiorenal Syndrome
Interventions
nesiritide, placebo
Drug
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 7, 2016 · Synced Jul 23, 2026, 6:22 PM EDT
Completed Phase 1 Interventional

Inhaled Milrinone Use in Patients Receiving HeartMate II LVAD: A Pilot Study

NCT01571037
View directory record Official record
Conditions
End Stage Heart Disease, Right Ventricular Dysfunction
Interventions
inhaled nebulized milrinone
Drug
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 5, 2023 · Synced Jul 23, 2026, 6:22 PM EDT
Completed Not applicable Interventional

Magenta Elevate™ EFS in High-Risk PCI Patients

NCT05727059
View directory record Official record
Conditions
High-risk Percutaneous Coronary Intervention
Interventions
The Elevate™ System
Device
Lead sponsor
Magenta Medical Ltd.
Industry
Eligibility
18 Years to 84 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 25, 2024 · Synced Jul 23, 2026, 6:22 PM EDT
Completed Phase 4 Interventional Results available

Prevention of Non-Surgical Bleeding by Management of HeartMate II Patients Without Antiplatelet Therapy

NCT02836652
View directory record Official record
Conditions
Heart Failure
Interventions
HeartMate II (HMII), Warfarin, acetylsalicylic acid (ASA) therapy
Device · Drug
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
50 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
33
States / cities
Birmingham, Alabama • Los Angeles, California • San Diego, California + 29 more
Source: ClinicalTrials.gov public record
Updated Jun 26, 2022 · Synced Jul 23, 2026, 6:22 PM EDT
Completed Not applicable Interventional Results available

A Clinical Trial to Evaluate the HeartWare™ Ventricular Assist System (ENDURANCE SUPPLEMENTAL TRIAL)

NCT01966458
View directory record Official record
Conditions
Chronic Heart Failure
Interventions
HeartWare® VAS (HVAD), Control LVAD
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
494 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
47
States / cities
Birmingham, Alabama • Phoenix, Arizona • Los Angeles, California + 37 more
Source: ClinicalTrials.gov public record
Updated Oct 22, 2020 · Synced Jul 23, 2026, 6:22 PM EDT
Enrolling by invitation Not applicable Interventional

EXCOR Active Driving System for the EXCOR Pediatric VAD IDE Study

NCT05610787
View directory record Official record
Conditions
Heart Failure, Transplant; Failure, Heart, Congenital Heart Disease
Interventions
EXCOR Active Driving System for Pediatric VAD
Device
Lead sponsor
Berlin Heart, Inc
Industry
Eligibility
Up to 21 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
15
States / cities
Los Angeles, California • Palo Alto, California • Aurora, Colorado + 12 more
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Jul 23, 2026, 6:22 PM EDT
Completed No phase listed Observational

Thoratec's Reduce Driveline Trauma Through Stabilization and Exit Site Management Study

NCT01485666
View directory record Official record
Conditions
Left Ventricular Assist Device, Percutaneous Lead Management
Interventions
Percutaneous Lead Management Kit
Other
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
16 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
5
States / cities
Birmingham, Alabama • San Diego, California • Ann Arbor, Michigan + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 23, 2022 · Synced Jul 23, 2026, 6:22 PM EDT
Completed No phase listed Observational

Right Ventricular Failure After Implantation of Left Ventricular Assist Devices

NCT01999712
View directory record Official record
Conditions
Heart Failure
Interventions
Echocardiography
Procedure
Lead sponsor
Emory University
Other
Eligibility
18 Years to 75 Years
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated May 30, 2018 · Synced Jul 23, 2026, 6:22 PM EDT
Terminated Phase 4 Interventional Results available

Angiotensin II for Distributive Shock

NCT04904562
View directory record Official record
Conditions
Distributive Shock
Interventions
Angiotensin II, Placebo
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Jul 23, 2026, 6:22 PM EDT
Completed No phase listed Observational

Cardiac Resynchronization Therapy (CRT) and Left Ventricular Assist Devices (LVAD) Therapy

NCT02083419
View directory record Official record
Conditions
Heart Failure
Interventions
LVAD CRT
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Feb 7, 2017 · Synced Jul 23, 2026, 6:22 PM EDT
Completed No phase listed Observational

Postoperative Tolvaptan Use in Left Ventricular Assist Device Implantation Patients

NCT05408104
View directory record Official record
Conditions
Heart Failure, Heart Assist Device, Hyponatremic
Interventions
tolvaptan
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 6, 2022 · Synced Jul 23, 2026, 6:22 PM EDT
Not listed No phase listed Observational

Skeletal Muscle Perfusion With LVAD

NCT02105831
View directory record Official record
Conditions
Heart Failure
Interventions
Contrast ultrasound skeletal muscle perfusion imaging
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 22, 2018 · Synced Jul 23, 2026, 6:22 PM EDT
Completed Not applicable Interventional

Wheeled Mobility in Everyday Life

NCT00981344
View directory record Official record
Conditions
Chronic Heart Disorder, Lung Disorder, Arthritis
Interventions
Wheeled Mobility in Everyday Life:Effects of Wheelchair Type on Mobility Performance of Elders in Public Environments
Other
Lead sponsor
Duke University
Other
Eligibility
Not listed
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
2
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 8, 2012 · Synced Jul 23, 2026, 6:22 PM EDT
Completed No phase listed Observational

Data Collection During CT for Axial Flow VADs

NCT00427739
View directory record Official record
Conditions
Heart Failure
Interventions
Cardiac CT
Procedure
Lead sponsor
Subha Raman
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 30, 2017 · Synced Jul 23, 2026, 6:22 PM EDT
Completed Not applicable Interventional Results available

Thoratec HeartMate II Left Ventricular Assist System (LVAS) for Bridge to Cardiac Transplantation

NCT00121472
View directory record Official record
Conditions
Heart Failure, Congestive, Ventricular Dysfunction, Cardiomyopathies
Interventions
Thoratec HeartMate II Left Ventricular Assist System (LVAS)
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
Not listed
Enrollment
194 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
34
States / cities
Birmingham, Alabama • Phoenix, Arizona • San Diego, California + 30 more
Source: ClinicalTrials.gov public record
Updated Jun 26, 2022 · Synced Jul 23, 2026, 6:22 PM EDT
Terminated No phase listed Observational

The Epidemiology of Bleeding and Clotting in Patients Undergoing Heart Transplantation, Coronary Artery Bypass Graft Surgery,or Implantation of Left Ventricular Assist Devices

NCT01481012
View directory record Official record
Conditions
Congestive Heart Failure
Interventions
Not listed
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
13
States / cities
Birmingham, Alabama • San Diego, California • Oak Lawn, Illinois + 10 more
Source: ClinicalTrials.gov public record
Updated Nov 28, 2011 · Synced Jul 23, 2026, 6:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Use of Simulation to Improve VAD Self-management

NCT03073005
View directory record Official record
Conditions
Heart Failure
Interventions
Simulation-based Mastery Learning (SBML)
Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
143 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 9, 2021 · Synced Jul 23, 2026, 6:22 PM EDT
Completed Not applicable Interventional Results available

MOMENTUM 3 Continued Access Protocol

NCT02892955
View directory record Official record
Conditions
Advanced Refractory Left Ventricular Heart Failure
Interventions
HeartMate 3 LVAS
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years to 100 Years
Enrollment
1,685 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
69
States / cities
Little Rock, Arkansas • Beverly Hills, California • La Jolla, California + 53 more
Source: ClinicalTrials.gov public record
Updated Jun 26, 2022 · Synced Jul 23, 2026, 6:22 PM EDT
Completed Not applicable Interventional Results available

Ventricular Assist Device Anti-Factor Xa (VAD ANTIX) Monitoring Study: a Prospective Randomized Feasibility Trial

NCT03143569
View directory record Official record
Conditions
Left Sided Heart Failure, Left Ventricular Assist Device, Anticoagulant Therapy, Gastro Intestinal Bleeding, Thrombosis, LVAD, Anti-factor Xa, aPTT, Heparin
Interventions
aPTT guided heparin management, Anti-factor Xa guided heparin management
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 24, 2020 · Synced Jul 23, 2026, 6:22 PM EDT
Completed No phase listed Observational

Hemodynamic Assessment of the Right Ventricle Using Pressure-volume Loop Catheter and Pulmonary Artery Catheter in Patients Undergoing Left Ventricular Assist Device Placement

NCT04478890
View directory record Official record
Conditions
Right Ventricular Dysfunction
Interventions
Hemodynamic assessment
Diagnostic Test
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 3, 2025 · Synced Jul 23, 2026, 6:22 PM EDT
Recruiting Not applicable Interventional

LVAD Conditioning for Cardiac Recovery

NCT03238690
View directory record Official record
Conditions
Heart Failure
Interventions
Controlled Cardiac Reloading through LVAD Speed Adjustment
Device
Lead sponsor
STAVROS G DRAKOS
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2028
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 14, 2025 · Synced Jul 23, 2026, 6:22 PM EDT
Recruiting Phase 4 Interventional

Aspirin and Hemocompatibility Events in Chronic Advanced Heart Failure Patients With Assist Device

NCT06655376
View directory record Official record
Conditions
Bleeding, Clot Blood
Interventions
Aspirin, Warfarin
Drug
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
3
States / cities
Chicago, Illinois • New York, New York • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Jul 23, 2026, 6:22 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Stem Cell Therapy in Patients With Severe Heart Failure & Undergoing Left Ventricular Assist Device Placement

NCT00869024
View directory record Official record
Conditions
Heart Failure
Interventions
Intramyocardial Delivery of Bone Marrow Derived Mononuclear Cells
Biological
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 80 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 12, 2020 · Synced Jul 23, 2026, 6:22 PM EDT
Completed Not applicable Interventional Results available

C-Pulse IDE Feasibility Study- A Heart Assist System

NCT00815880
View directory record Official record
Conditions
Heart Failure
Interventions
C-Pulse™ (Implantable Counterpulsation Therapy)
Device
Lead sponsor
Nuwellis, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2018
U.S. locations
6
States / cities
Birmingham, Alabama • Louisville, Kentucky • Saint Paul, Minnesota + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 23, 2023 · Synced Jul 23, 2026, 6:22 PM EDT