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Showing 1–24 of 70 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Heart Rate Control Clear all
Completed Phase 1 Interventional Accepts healthy volunteers

Study to Evaluate the QTC Interval in Healthy Volunteers Dosed With Dexpramipexole (QTC = Electrocardiogram (ECG) Interval Measured From the Onset of the QRS Complex to the End of the T Wave Corrected for Heart Rate)

NCT01511029
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis
Interventions
Dexpramipexole, Dexpramipexole Placebo, Moxifloxacin
Drug
Lead sponsor
Knopp Biosciences
Industry
Eligibility
18 Years to 60 Years
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
Overland Park, Kansas
Source: ClinicalTrials.gov public record
Updated Nov 24, 2014 · Synced Sep 8, 2026, 7:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Cognitive Behavioral Stress Intervention for Women Who Smoke

NCT03077945
View directory record Official record
Conditions
Smoking, Cigarette, Smoking Cessation, Stress, Stress, Emotional, Stress Reaction
Interventions
heart rate variability biofeedback and cognitive reappraisal, control tasks
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 13, 2018 · Synced Sep 8, 2026, 7:08 PM EDT
Completed Not applicable Interventional

The Effect of Maternal Scent on Sleep Wake States

NCT04301453
View directory record Official record
Conditions
Development, Infant
Interventions
Maternal Scent
Other
Lead sponsor
Columbia University
Other
Eligibility
30 Weeks to 36 Weeks
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 25, 2022 · Synced Sep 8, 2026, 7:08 PM EDT
Terminated Not applicable Interventional

Sensible Medical Innovations Lung fLuid Status Monitor Allows rEducing Readmission Rate of Heart Failure Patients

NCT02448342
View directory record Official record
Conditions
Heart Failure
Interventions
Remote Dielectric Sensing (ReDS) Wearable System
Device
Lead sponsor
Sensible Medical Innovations Ltd.
Industry
Eligibility
21 Years and older
Enrollment
380 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
41
States / cities
Birmingham, Alabama • Hollywood, California • La Jolla, California + 34 more
Source: ClinicalTrials.gov public record
Updated Dec 28, 2017 · Synced Sep 8, 2026, 7:08 PM EDT
Completed Not applicable Interventional Results available

Feasibility Study of Closed Loop Control in Type 1 Diabetes Using Heart Rate Monitoring as an Exercise Marker

NCT01582139
View directory record Official record
Conditions
Type 1 Diabetes Mellitus
Interventions
Heart rate informed SSM+HMM
Device
Lead sponsor
University of Virginia
Other
Eligibility
21 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 14, 2014 · Synced Sep 8, 2026, 7:08 PM EDT
Recruiting Phase 2Phase 3 Interventional

Randomized Controlled Trial of Treatment to Optimize Heart Rate Variability for Persistent Post-Concussion Symptoms

NCT07071350
View directory record Official record
Conditions
Autonomic Nervous System Disease, Concussive Injury, Mild Traumatic Brain Injury, Post Traumatic Stress Disorder, Persistent Post Concussion Syndrome
Interventions
HRV Coherence Ratio, NSI, Pittsburgh Sleep Quality Index (PSQI), Quantitative Sleep Measures, Patient Global Impression of Change (PGIC), Cognitive Performance/NIH Toolbox Cognitive Battery, Pain Interference/TBI-QoL Pain Interference Short-Form, Patient Health Questionnaire-9 (PHQ-9), PTSD Checklist for DSM-5 (PCL-5), HRV Biofeedback (HRV-B), Psychoeducational (Edu) Comparator Intervention
Other · Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced Sep 8, 2026, 7:08 PM EDT
Completed Phase 2Phase 3 Interventional

Comparing Paroxetine and Duloxetine on Cardiovascular Measures

NCT00136383
View directory record Official record
Conditions
Depressive Symptoms
Interventions
paroxetine versus duloxetine
Drug
Lead sponsor
Duke University
Other
Eligibility
20 Years to 60 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 20, 2014 · Synced Sep 8, 2026, 7:08 PM EDT
Completed Phase 3 Interventional Results available

Efficacy Study of Pioglitazone Compared to Glimepiride on Coronary Atherosclerotic Disease Progression in Subjects With Type 2 Diabetes Mellitus

NCT00225277
View directory record Official record
Conditions
Diabetes Mellitus
Interventions
Pioglitazone, Glimepiride
Drug
Lead sponsor
Takeda
Industry
Eligibility
35 Years to 85 Years
Enrollment
547 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
65
States / cities
Birmingham, Alabama • Phoenix, Arizona • Huntington Beach, California + 62 more
Source: ClinicalTrials.gov public record
Updated Feb 27, 2012 · Synced Sep 8, 2026, 7:08 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Pharmacologic Effects of Darifenacin and Tolterodine on Cardiovascular Parameters in Healthy Subjects

NCT00703703
View directory record Official record
Conditions
Healthy
Interventions
Darifenacin, Tolterodine, Placebo
Drug
Lead sponsor
Novartis
Industry
Eligibility
50 Years and older
Enrollment
117 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
21
States / cities
Phoenix, Arizona • Tempe, Arizona • Little Rock, Arkansas + 18 more
Source: ClinicalTrials.gov public record
Updated Aug 1, 2012 · Synced Sep 8, 2026, 7:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Afferent Neurocardiac Signals, Cue Reactivity, and Cognitive Control

NCT05369169
View directory record Official record
Conditions
Binge Drinking
Interventions
Resonance breathing, Low demand cognitive task
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 35 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 19, 2026 · Synced Sep 8, 2026, 7:08 PM EDT
Withdrawn Phase 4 Interventional

Assessment of Intravenous Rate Control Response in Atrial Fibrillation Trial (AIRCRAFT)

NCT04234477
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Beta-blocker strategy, Calcium channel blocker strategy, Physician preference strategy
Drug
Lead sponsor
Boston University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 14, 2021 · Synced Sep 8, 2026, 7:08 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Study to Evaluate the Effect of ACP-196 on the Heart Rate-corrected QT Interval in Healthy Adult Participants

NCT04867980
View directory record Official record
Conditions
Healthy Volunteers
Interventions
ACP-196, Moxifloxacin 400 mg, Placebo
Drug
Lead sponsor
Acerta Pharma BV
Industry
Eligibility
18 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Tempe, Arizona
Source: ClinicalTrials.gov public record
Updated Apr 29, 2021 · Synced Sep 8, 2026, 7:08 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

UCLA Magnesium Formulation Athlete Study

NCT07640685
View directory record Official record
Conditions
Athletic Performance, Recovery, Sleep
Interventions
Magnesium glycinate, Magnesium L-threonate, Placebo
Dietary Supplement · Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 35 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Sep 8, 2026, 7:08 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

BPIT 5-Week Multi-Site Study: Movement Efficiency, Mobility & Neuromuscular Adaptation

NCT07256717
View directory record Official record
Conditions
Physical Fitness
Interventions
Balanced Progressive Intensity Training (BPIT) 5-Line Method
Behavioral
Lead sponsor
MMSx Authority Institute for Movement Mechanics & Biomechanics Research Inc.
Other
Eligibility
18 Years to 65 Years
Enrollment
369 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
3
States / cities
Columbus, Ohio • Powell, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 15, 2025 · Synced Sep 8, 2026, 7:08 PM EDT
Completed Phase 4 Interventional

Resync-AF (Rate vs Rhythm Control in AF Patients With CRT-D)

NCT01233648
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
rate control via CRT-D and AVN ablation, rhythm control via pharmacologic, electrical or ablative therapies
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2015
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 22, 2023 · Synced Sep 8, 2026, 7:08 PM EDT
Completed Not applicable Interventional Results available

Pulse Pressure and Post-epidural Fetal Heart Rate Changes

NCT02565485
View directory record Official record
Conditions
Fetus or Neonate Affected by Maternal Epidural Anesthesia During Labor and Delivery
Interventions
Lactated Ringer's
Drug
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
276 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 8, 2018 · Synced Sep 8, 2026, 7:08 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Ivabradine for Rate Control in Permanent Atrial Fibrillation

NCT03987204
View directory record Official record
Conditions
Atrial Fibrillation, Atrial Fibrillation, Persistent
Interventions
Ivabradine
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years to 90 Years
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 1, 2021 · Synced Sep 8, 2026, 7:08 PM EDT
Completed Phase 2Phase 3 Interventional

MARS - Monitored Atherosclerosis Regression Study

NCT00116870
View directory record Official record
Conditions
Atherosclerosis, Coronary Artery Disease
Interventions
lovastatin
Drug
Lead sponsor
Merck Sharp & Dohme LLC
Industry
Eligibility
21 Years to 67 Years
Enrollment
270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1985 – 1992
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 10, 2009 · Synced Sep 8, 2026, 7:08 PM EDT
Completed Not applicable Interventional

Kangaroo Care and Premature Infant Sleep

NCT02473055
View directory record Official record
Conditions
Premature Birth of Newborn
Interventions
Kangaroo Care
Other
Lead sponsor
Case Western Reserve University
Other
Eligibility
7 Days to 37 Weeks
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2015
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 17, 2015 · Synced Sep 8, 2026, 7:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Physiological Mechanisms of Therapeutic Horseback Riding Intervention Effects in a Psychiatric Population of ASD Youth

NCT04606966
View directory record Official record
Conditions
Autism Spectrum Disorder, Mental Disorders
Interventions
Therapeutic Horseback Riding, Barn Activity, Hybrid
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
6 Years to 17 Years
Enrollment
236 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
2
States / cities
Aurora, Colorado • Portland, Maine
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Sep 8, 2026, 7:08 PM EDT
Completed Not applicable Interventional

Osteopathic Manual Treatment Parkinson's Disease and Truncal Dystonia

NCT03307161
View directory record Official record
Conditions
Parkinson Disease, Dystonia, Autonomic Dysreflexia
Interventions
osteopathic manual therapy
Other
Lead sponsor
New York Institute of Technology
Other
Eligibility
Not listed
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Sep 22, 2021 · Synced Sep 8, 2026, 7:08 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Effect on the Electrocardiographic QT Interval Corrected for Heart Rate (QTc) in Healthy Subjects

NCT00979316
View directory record Official record
Conditions
Alzheimer Disease
Interventions
BMS-708163, Placebo, Moxifloxacin
Drug
Lead sponsor
Bristol-Myers Squibb
Industry
Eligibility
18 Years to 55 Years
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Tempe, Arizona
Source: ClinicalTrials.gov public record
Updated Jan 6, 2011 · Synced Sep 8, 2026, 7:08 PM EDT
Withdrawn Not applicable Interventional

Heart Rate Variability-Guided Exercise Training in Type 2 Diabetes

NCT04910997
View directory record Official record
Conditions
Type 2 Diabetes, Diabetes Mellitus, Type 2, Type 2 Diabetes Mellitus in Obese
Interventions
Aerobic exercise training
Other
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
40 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 17, 2023 · Synced Sep 8, 2026, 7:08 PM EDT
Completed Not applicable Interventional

Trial to Evaluate the Effects of Sound Modulation on Critically Ill Patients

NCT03019133
View directory record Official record
Conditions
Critical Illness, Physiological Stress, Delirium, Sleep Deprivation
Interventions
Sound reduction, Sound masking
Device
Lead sponsor
Brian Gehlbach
Other
Eligibility
18 Years to 99 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2024
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Apr 5, 2025 · Synced Sep 8, 2026, 7:08 PM EDT