Independent directory Public ClinicalTrials.gov records United States
Clinical Trials Finder
Objective public record navigation
Search Results

Search by objective public record fields.

Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.

Clear filters
ClinicalTrials.gov public records Last synced Jul 21, 2026, 4:01 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 197 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Heart Rate Variability Clear all
Completed Not applicable Interventional Results available

Relaxation and Heart Rate Variability

NCT00735618
View directory record Official record
Conditions
Cancer
Interventions
Guided Relaxation
Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 18, 2011 · Synced Jul 21, 2026, 4:01 PM EDT
Completed Phase 2 Interventional Results available

Heart Rate Variability in Response to Metformin Challenge

NCT02500628
View directory record Official record
Conditions
Fibromyalgia, Mitochondrial Diseases, Movement Disorders, Diabetes Mellitus, Type 2
Interventions
Metformin
Drug
Lead sponsor
Woodinville Psychiatric Associates
Other
Eligibility
18 Years and older
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Woodinville, Washington
Source: ClinicalTrials.gov public record
Updated Jan 2, 2018 · Synced Jul 21, 2026, 4:01 PM EDT
Completed Phase 4 Interventional Results available

To Evaluate the Effect of Liraglutide on Ambulatory Blood Pressure-A Pilot Study

NCT02299388
View directory record Official record
Conditions
Diabetes Mellitus, Non-Insulin-Dependent, Hypertensive Disease
Interventions
Liraglutide or Placebo
Drug
Lead sponsor
Tulane University School of Medicine
Other
Eligibility
18 Years to 75 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Jan 26, 2021 · Synced Jul 21, 2026, 4:01 PM EDT
Completed No phase listed Observational

Treatment of Reduced Heart Rate Variability Associated With Major Depression With Electroconvulsive Therapy

NCT00209066
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Not listed
Lead sponsor
Emory University
Other
Eligibility
18 Years to 90 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2005
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Nov 18, 2013 · Synced Jul 21, 2026, 4:01 PM EDT
Completed Phase 2 Interventional

Acceptability and Feasibility of Apollo in Veterans With a History of PTSD

NCT05019651
View directory record Official record
Conditions
PTSD
Interventions
Apollo Wearable System
Device
Lead sponsor
Lisa Brenner
Federal
Eligibility
18 Years to 65 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 16, 2025 · Synced Jul 21, 2026, 4:01 PM EDT
Completed Not applicable Interventional

Coherence Training for Military Personnel

NCT01599598
View directory record Official record
Conditions
Stress
Interventions
Progressive Muscle Relaxation, Coherence Advantage
Behavioral
Lead sponsor
United States Naval Medical Center, San Diego
Federal
Eligibility
Not listed
Enrollment
192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 18, 2016 · Synced Jul 21, 2026, 4:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Investigating Real-world Stress-related Mechanisms in Heavy Cannabis Users

NCT05833230
View directory record Official record
Conditions
Cannabis Use, Cannabis, Cannabis Abuse
Interventions
Intensive Day Monitoring
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 3, 2025 · Synced Jul 21, 2026, 4:01 PM EDT
Completed No phase listed Observational

Gestational Diabetes and Sleep-Disordered Breathing

NCT00933881
View directory record Official record
Conditions
Gestational Diabetes Mellitus
Interventions
Determining a change in heart rate variability post delivery of the baby
Other
Lead sponsor
Christiana Care Health Services
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Jul 13, 2016 · Synced Jul 21, 2026, 4:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Hot Water Immersion on Heart Rate Variability and Glucose

NCT06193291
View directory record Official record
Conditions
Glucose Tolerance, HRV
Interventions
Feet heating, Calf heating
Procedure
Lead sponsor
San Diego State University
Other
Eligibility
18 Years to 65 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jan 7, 2024 · Synced Jul 21, 2026, 4:01 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Effects of Mid-thoracic Manipulation on Heart Rate Variability.

NCT02379871
View directory record Official record
Conditions
Neurophysiological Mechanisms Underlying Spinal Manipulation
Interventions
Experimental Group, Sham Group
Other
Lead sponsor
Mount St. Mary's College, Los Angeles, CA
Other
Eligibility
18 Years to 55 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 4, 2015 · Synced Jul 21, 2026, 4:01 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Effects of Single-Pulse Transcranial Magnetic Stimulation on the Autonomic Nervous System in Healthy Adults

NCT02833220
View directory record Official record
Conditions
Healthy
Interventions
Single-Pulse Transcranial Magnetic Stimulation
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 15, 2019 · Synced Jul 21, 2026, 4:01 PM EDT
Completed Not applicable Interventional Results available

RCT of Effects of Device-guided Breathing on Ambulatory BP

NCT01184755
View directory record Official record
Conditions
Hypertension
Interventions
Relaxation, RESPeRate
Behavioral · Device
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 80 Years
Enrollment
253 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
2
States / cities
New Brunswick, New Jersey • New York, New York
Source: ClinicalTrials.gov public record
Updated May 15, 2017 · Synced Jul 21, 2026, 4:01 PM EDT
Completed Not applicable Interventional

The Effect of Maternal Scent on Sleep Wake States

NCT04301453
View directory record Official record
Conditions
Development, Infant
Interventions
Maternal Scent
Other
Lead sponsor
Columbia University
Other
Eligibility
30 Weeks to 36 Weeks
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 25, 2022 · Synced Jul 21, 2026, 4:01 PM EDT
Completed Not applicable Interventional

Evaluating the Feasibility, Acceptability, and Preliminary Outcomes of Heart Rate Variability Biofeedback for Individuals With Opioid Use Disorder.

NCT07361731
View directory record Official record
Conditions
Autonomic Nervous System Imbalance, Heart Rate Variability (HRV), Opioid Use Disorder, Breathing Techniques, Opioid Craving, Recovery, Emotional Regulation, Positive and Negative Affect, Stress, Biofeedback
Interventions
Heart rate variability biofeedback
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
18 Years to 65 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Jul 21, 2026, 4:01 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Pediatric Hypertension and the Renin-Angiotensin SystEm (PHRASE)

NCT04752293
View directory record Official record
Conditions
Hypertension, Left Ventricular Hypertrophy, Left Ventricular Dysfunction, Left Atrial Dilatation, Left Ventricular Diastolic Dysfunction, Kidney Diseases, Kidney Injury, Kidney Dysfunction, Sodium Urine High, Blood Pressure Disorders, Uric Acid Retention, Angiotensin Hypertension, Autonomic Dysfunction, Autonomic Imbalance, Pediatric Kidney Disease, Pediatric Obesity, Proteinuria, Albuminuria
Interventions
Not listed
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
7 Years to 18 Years
Enrollment
125 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 10, 2025 · Synced Jul 21, 2026, 4:01 PM EDT
Recruiting Not applicable Interventional

Benefits of Choir for Older Adults With Unaddressed Hearing Loss (WP2)

NCT06580847
View directory record Official record
Conditions
Hearing Loss, Age-Related, Speech Intelligibility, Psychosocial Functioning
Interventions
Group Singing, Audiobook Club
Behavioral
Lead sponsor
Toronto Metropolitan University
Other
Eligibility
60 Years and older
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 17, 2025 · Synced Jul 21, 2026, 4:01 PM EDT
Withdrawn No phase listed Observational

Electrocardiographic Autonomic Function Measures in Mechanically Ventilated Patients

NCT00844935
View directory record Official record
Conditions
Disorders of the Autonomic Nervous System, Cardiovascular Abnormalities, Respiratory Disorders
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 27, 2012 · Synced Jul 21, 2026, 4:01 PM EDT
Completed Not applicable Interventional

Interval Training and Parkinson's Disease

NCT06606743
View directory record Official record
Conditions
Other Disorders of Autonomic Nervous System
Interventions
High-Intensity Interval Training, High-Velocity Circuit Resistance Training
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
30 Years to 90 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
2
States / cities
Coral Gables, Florida
Source: ClinicalTrials.gov public record
Updated Aug 14, 2025 · Synced Jul 21, 2026, 4:01 PM EDT
Recruiting Phase 2Phase 3 Interventional

Randomized Controlled Trial of Treatment to Optimize Heart Rate Variability for Persistent Post-Concussion Symptoms

NCT07071350
View directory record Official record
Conditions
Autonomic Nervous System Disease, Concussive Injury, Mild Traumatic Brain Injury, Post Traumatic Stress Disorder, Persistent Post Concussion Syndrome
Interventions
HRV Coherence Ratio, NSI, Pittsburgh Sleep Quality Index (PSQI), Quantitative Sleep Measures, Patient Global Impression of Change (PGIC), Cognitive Performance/NIH Toolbox Cognitive Battery, Pain Interference/TBI-QoL Pain Interference Short-Form, Patient Health Questionnaire-9 (PHQ-9), PTSD Checklist for DSM-5 (PCL-5), HRV Biofeedback (HRV-B), Psychoeducational (Edu) Comparator Intervention
Other · Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced Jul 21, 2026, 4:01 PM EDT
Terminated Not applicable Interventional Results available

Feasibility Study of Omega-3 Fatty Acids in Dialysis Patients

NCT01002118
View directory record Official record
Conditions
Cardiovascular Disease
Interventions
Omega-3 Acid Ethyl Esters, Placebo
Drug
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 70 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Aug 8, 2017 · Synced Jul 21, 2026, 4:01 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Diaphragmatic Breathing and Heart Rate Variability Training for Improving Hypertension in Fragile X Associated Tremor/Ataxia

NCT03816540
View directory record Official record
Conditions
Hypertension, FXTAS
Interventions
HRV and respiratory coherence biofeedback
Device
Lead sponsor
University of California, Davis
Other
Eligibility
50 Years to 90 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Oct 21, 2019 · Synced Jul 21, 2026, 4:01 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Pranayama Practice on the Autonomic Nervous System

NCT03280589
View directory record Official record
Conditions
Pranayama Effect on Autonomic Nervous System, Respiration Variability Effect on Nervous System
Interventions
Sheetali/Sheekari Pranayama, Sitting Quietly, Deep breathing
Other
Lead sponsor
National University of Natural Medicine
Other
Eligibility
25 Years to 55 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 23, 2023 · Synced Jul 21, 2026, 4:01 PM EDT
Not listed Phase 1Phase 2 Interventional Accepts healthy volunteers

The Effect of Acupuncture on Blood Pressure and Heart Rate Variability (HRV)

NCT00724763
View directory record Official record
Conditions
Hypertension
Interventions
acupuncture, sham needle treatment
Device
Lead sponsor
Logan College of Chiropractic
Other
Eligibility
20 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2008
U.S. locations
1
States / cities
Chesterfield, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 29, 2008 · Synced Jul 21, 2026, 4:01 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Does Style Matter: Comparison of Moderate- to Low-intensity Styles of Yoga

NCT07638267
View directory record Official record
Conditions
Insomnia, Health Adult Subjects, Insomnia Disorder, Heart Health Markers
Interventions
Vinyasa yoga, Gentle yoga, Non-active control
Behavioral · Other
Lead sponsor
Caitlin Cheruka
Other
Eligibility
18 Years to 40 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Jul 21, 2026, 4:01 PM EDT