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Showing 1–24 of 1,573 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Heart Rhythm Disorder Clear all
Withdrawn Phase 4 Interventional

Comparison of Reverse Remodeling and PVI Versus CFAE and/or Linear Lesions and PVI for Persistent AF

NCT01877473
View directory record Official record
Conditions
Persistent Atrial Fibrillation
Interventions
Ablation
Procedure
Lead sponsor
Valley Health System
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Ridgewood, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 16, 2014 · Synced Sep 4, 2026, 4:02 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Ivabradine for Rate Control in Permanent Atrial Fibrillation

NCT03987204
View directory record Official record
Conditions
Atrial Fibrillation, Atrial Fibrillation, Persistent
Interventions
Ivabradine
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years to 90 Years
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 1, 2021 · Synced Sep 4, 2026, 4:02 PM EDT
Completed Not applicable Interventional Results available

Multicenter Automatic Defibrillator Implantation Trial With Subcutaneous Implantable Cardioverter Defibrillator

NCT02787785
View directory record Official record
Conditions
Tachycardia, Diabetes Mellitus, Cardiovascular Disease
Interventions
Subcutaneous Implantable Cardioverter Defibrillator
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
65 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
36
States / cities
Huntsville, Alabama • Scottsdale, Arizona • Jonesboro, Arkansas + 31 more
Source: ClinicalTrials.gov public record
Updated Aug 21, 2024 · Synced Sep 4, 2026, 4:02 PM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Cor360: Clinician-Facing Broad-Spectrum Cardiac Phenotyping and Risk Assessment Using COR® Wearable ECG to Inform Outcomes-Oriented Care Pathways

NCT07775976
View directory record Official record
Conditions
Cardiovascular Diseases, Cardiovascular Diseases Risk, Cardiac Conduction System Disease, Bundle/Fascicular Abnormalities, His-Purkinje Disease, Arrhythmias, Cardiac, Rhythm Phenotypes, Myocardial Ischemia, Syncope, Syncope Recurrent, Syncope and Collapse, Seizure Disorder, Sleep Apnea Syndrome, Obstructive, Decision Support Systems, Clinical, Heart Failure - NYHA II - IV, Heart Failure (for Example, Fluid Overload), HRV, Cardiopulmonary, Sudden Cardiac Arrest, Cardiac Arrest (CA), Ventricular Arrhythmias and Cardiac Arrest, Ventricular Fibrillation, QT Dispersion, Atrial Cardiomyopathy
Interventions
COR Wearable ECG Monitoring, Cor360 Clinician-Facing Decision-Aid Reporting
Device · Other
Lead sponsor
Peerbridge Health, Inc
Industry
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
2
States / cities
Pasadena, California • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Sep 4, 2026, 4:02 PM EDT
Completed Not applicable Interventional Results available

SJM MRI Diagnostic Imaging Registry (IDE)

NCT02807948
View directory record Official record
Conditions
Cardiac Arrhythmia
Interventions
Pacemaker, ICD, or CRT device
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
189 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
58
States / cities
Scottsdale, Arizona • Tucson, Arizona • Jonesboro, Arkansas + 55 more
Source: ClinicalTrials.gov public record
Updated Aug 25, 2019 · Synced Sep 4, 2026, 4:02 PM EDT
Terminated Not applicable Interventional Results available

Atrial Pressure Electrophysiology Pilot Study

NCT01845974
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
ThermoCool® SF NAV Catheter, ThermoCool® catheter
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Park Ridge, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 2, 2024 · Synced Sep 4, 2026, 4:02 PM EDT
Completed Not applicable Interventional

Prematurity Related Ventilatory Control (PRE-VENT) - Specific Aim 3

NCT03333174
View directory record Official record
Conditions
Infant,Premature
Interventions
Cardiorespiratory monitoring
Diagnostic Test
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
1 Day to 98 Days
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 20, 2021 · Synced Sep 4, 2026, 4:02 PM EDT
Terminated No phase listed Observational

His Bundle Recording From Subclavian Vein

NCT04115735
View directory record Official record
Conditions
Atrial Fibrillation, Congestive Heart Failure
Interventions
Not listed
Lead sponsor
TriHealth Inc.
Other
Eligibility
18 Years to 105 Years
Enrollment
1 participant
Timeline
2019 – 2020
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 7, 2023 · Synced Sep 4, 2026, 4:02 PM EDT
Withdrawn Phase 2 Interventional

Apixaban in Patients Who Undergo CIED Procedure- Randomized Pilot Study

NCT02450682
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Apixaban, Warfarin
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 17, 2016 · Synced Sep 4, 2026, 4:02 PM EDT
Completed No phase listed Observational

Using Near-infrared Spectroscopy (NIRS) Monitor to Noninvasively Evaluate Hepatic Venous Saturation

NCT01891188
View directory record Official record
Conditions
Congenital Heart Disease, Arrhythmia
Interventions
Not listed
Lead sponsor
Phoenix Children's Hospital
Other
Eligibility
1 Day to 18 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Jan 22, 2026 · Synced Sep 4, 2026, 4:02 PM EDT
Terminated Not applicable Interventional

Arterial Stiffness and Atrial Fibrillation

NCT04160663
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Carotid Ultrasound
Diagnostic Test
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 95 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 16, 2023 · Synced Sep 4, 2026, 4:02 PM EDT
Completed No phase listed Observational

Patient Status Engine (PSE): EARLY FEASIBILITY AND USABILITY STUDY

NCT03480204
View directory record Official record
Conditions
Cardiac Arrhythmia
Interventions
Not listed
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 18, 2019 · Synced Sep 4, 2026, 4:02 PM EDT
Completed No phase listed Observational

Heart Rate Changes Following the Administration of Sugammadex

NCT03294018
View directory record Official record
Conditions
Bradycardia
Interventions
Recording heart rate changes
Other
Lead sponsor
Joseph D. Tobias
Other
Eligibility
Up to 18 Years
Enrollment
276 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 8, 2019 · Synced Sep 4, 2026, 4:02 PM EDT
Completed No phase listed Observational Results available

Physiologic Pacing Registry

NCT03719040
View directory record Official record
Conditions
Bradycardia, Sinus Node Dysfunction, Heart Block, Syncope, Cardiomyopathies, Ventricular Tachycardia, Heart Failure
Interventions
Physiologic pacing device implant
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
870 participants
Timeline
2018 – 2021
U.S. locations
26
States / cities
Huntsville, Alabama • Burlingame, California • San Diego, California + 22 more
Source: ClinicalTrials.gov public record
Updated Aug 18, 2024 · Synced Sep 4, 2026, 4:02 PM EDT
Recruiting Not applicable Interventional

Ventricular Tachycardia Mechanisms

NCT05478213
View directory record Official record
Conditions
Ventricular Tachycardia
Interventions
Monophasic Action Potential (MAP) Catheter
Device
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
3
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Sep 4, 2026, 4:02 PM EDT
Completed Phase 4 Interventional Results available

Study of Continuous Cardiac Monitoring to Assess Atrial Fibrillation After Cryptogenic Stroke

NCT00924638
View directory record Official record
Conditions
Cryptogenic Symptomatic Transient Ischemic Attack, Cryptogenic Ischemic Stroke
Interventions
Reveal® XT Insertable Cardiac Monitor
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
40 Years and older
Enrollment
447 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
19
States / cities
Mountain View, California • Denver, Colorado • Chicago, Illinois + 15 more
Source: ClinicalTrials.gov public record
Updated Jul 27, 2014 · Synced Sep 4, 2026, 4:02 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

SmartWatch ECG Evaluation Trial I

NCT05942274
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
We propose to validate these smartwatch ECG functions to support FDA submissions
Diagnostic Test
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 90 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated May 21, 2024 · Synced Sep 4, 2026, 4:02 PM EDT
Completed Not applicable Interventional

MRI Assessment of Arrythmia Ablation Lesions

NCT02761343
View directory record Official record
Conditions
Ventricular Tachycardia, Cardiac Arrhythmia
Interventions
MRI scan
Other
Lead sponsor
Children's National Research Institute
Other
Eligibility
Not listed
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jan 20, 2020 · Synced Sep 4, 2026, 4:02 PM EDT
Completed No phase listed Observational Results available

NAVISTAR® THERMOCOOL® SF Catheter: Observational Study

NCT01585961
View directory record Official record
Conditions
Atrial Fibrillation, Paroxysmal Arrhythmia
Interventions
Catheter Ablation (NAVISTAR® THERMOCOOL® SF Catheter)
Device
Lead sponsor
Biosense Webster, Inc.
Industry
Eligibility
18 Years and older
Enrollment
511 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
45
States / cities
Huntsville, Alabama • Anchorage, Alaska • Phoenix, Arizona + 40 more
Source: ClinicalTrials.gov public record
Updated Jan 25, 2015 · Synced Sep 4, 2026, 4:02 PM EDT
Recruiting Not applicable Interventional

PREACTIVE: Preconditioning Exercise Intervention to Improve Symptoms and Quality of Life in Comorbid Atrial Fibrillation and HFpEF

NCT07324772
View directory record Official record
Conditions
Atrial Fibrillation (AF), Atrial Fibrillation (Paroxysmal), Persistent Atrial Fibrillation, Heart Failure With Preserved Ejection Fraction (HFPEF)
Interventions
progressive resistance training, combined aerobic + resistance training
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
60 Years to 99 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 23, 2026 · Synced Sep 4, 2026, 4:02 PM EDT
Completed Phase 2 Interventional Results available

Genetically Targeted Therapy for the Prevention of Symptomatic Atrial Fibrillation in Patients With Heart Failure

NCT01970501
View directory record Official record
Conditions
Current or Recent History of Atrial Fibrillation
Interventions
bucindolol hydrochloride, metoprolol succinate, Placebo oral capsule
Drug · Other
Lead sponsor
ARCA Biopharma, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
267 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
48
States / cities
Anchorage, Alaska • Phoenix, Arizona • East Palo Alto, California + 43 more
Source: ClinicalTrials.gov public record
Updated Sep 25, 2022 · Synced Sep 4, 2026, 4:02 PM EDT
Completed Phase 4 Interventional Results available

Antiarrhythmic Effects of Spironolactone in Patients With ICDs

NCT04495712
View directory record Official record
Conditions
Ventricular Arrhythmias
Interventions
spironolactone, placebo
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 8, 2020 · Synced Sep 4, 2026, 4:02 PM EDT
Completed Phase 4 Interventional Results available

Rhythm Evaluation for AntiCoagulaTion With COntinuous Monitoring

NCT01706146
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Non-coumadin Oral Anticoagulant
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
2
States / cities
Chicago, Illinois • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 22, 2016 · Synced Sep 4, 2026, 4:02 PM EDT
Withdrawn Not applicable Interventional

Effect of Right Ventricular Lead Position on Defibrillation Threshold

NCT02844127
View directory record Official record
Conditions
Ventricular Tachycardia, Ventricular Fibrillation
Interventions
Implantable Cardioverter Defibrillator (ICD)
Procedure
Lead sponsor
OhioHealth
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 18, 2017 · Synced Sep 4, 2026, 4:02 PM EDT