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Showing 1–24 of 131 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Heat Stress, Fatigue
Interventions
Hot Dry
Other
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years to 39 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Buffalo, New York
Recruiting No phase listed Observational

Genetic Risk Factor for Heat Stroke

NCT06847256
Conditions
Carrier State, Heat Stroke, Dehydration
Interventions
Heat Challenge
Procedure
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 60 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Muscle Recovery, Muscle Soreness, Glycogen Depletion
Interventions
Compression sleeve, Heat therapy, Glycogen-depleting exercise session, Nutrient Intake (beverage), Skeletal muscle biopsy
Device · Other · Procedure
Lead sponsor
PepsiCo Global R&D
Industry
Eligibility
18 Years to 35 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
West Lafayette, Indiana
Completed Not applicable Interventional Accepts healthy volunteers Results available

Bundling and Unbundling the Laparoscopic Electrosurgery Cord With the Camera Cord

NCT01707095
Conditions
Fatigue
Interventions
Unbundling of cords, Bundling of cords
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Aurora, Colorado
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Skin Surface and Intradermal Temperature Responses to Heat Stress

NCT06593067
Conditions
Hyperthermia
Interventions
Control, Fan, Fan and Water Spray, Water Spray
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Dallas, Texas
Completed Not applicable Interventional Accepts healthy volunteers

Renal Considerations in the Heat Stress Recommendations (Aim2)

NCT05458843
Conditions
Hot Weather; Adverse Effect, Kidney Dysfunction, Kidney Injury, Hyperthermia, Dehydration
Interventions
Fluid replacement, No fluid replacement
Procedure
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 44 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Bloomington, Indiana
Completed Not applicable Interventional Accepts healthy volunteers

Acquiring and Targeting Heat Exposures Necessary for Action

NCT05678738
Conditions
Heat Intolerance, Heat Stress, Fatigue; Heat
Interventions
Antioxidant Berry Supplementation, Acute and Chronic Exercise-Heat Stress, Placebo (non-juice) Supplementation
Dietary Supplement · Other
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years to 50 Years
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Storrs, Connecticut
Not listed No phase listed Observational Accepts healthy volunteers

Sickle Cell Trait in Football Players

NCT01891877
Conditions
Sickle Cell Trait
Interventions
Not listed
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older · Male only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Tampa, Florida
Conditions
Melanoma, Sarcoma
Interventions
double isolated limb perfusion with melphalan alone
Procedure
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
Not listed
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 2000
U.S. locations
1
States / cities
Bethesda, Maryland
Completed Not applicable Interventional Accepts healthy volunteers

Military Alerting System for Monitoring Body Temperature During Active Cooling

NCT04431596
Conditions
Hyperthermia
Interventions
Forearm cooling, Mist-fan cooling
Device · Other
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Storrs, Connecticut
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Passive Heat Therapy on Oxygen Consumption and Cardiovascular Fitness in Adults

NCT04026126
Conditions
Heart Failure, Heart Diseases, Cardiovascular Diseases, Endothelial Dysfunction
Interventions
Heat Therapy Treatment
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
50 Years to 75 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Kansas City, Kansas
Conditions
Heart Failure, Tachycardia, Ventricular
Interventions
Optimal placement of return pad
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older
Enrollment
167 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Portland, Oregon
Withdrawn Not applicable Interventional Accepts healthy volunteers

Biomarkers to Assess Acute Kidney Injury Risk During Heat Strain

NCT05710978
Conditions
Hyperthermia, Kidney Injury, Acute
Interventions
Work Protocol
Other
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years to 39 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Buffalo, New York
Conditions
Valvular Heart Disease, Aortic Valve Failure
Interventions
TELLTALE BASILICA procedure
Device
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
21 Years to 109 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
10
States / cities
San Francisco, California • Fort Collins, Colorado • Washington D.C., District of Columbia + 7 more
Conditions
Breast Cancer
Interventions
Focused Microwave Thermotherapy, Chemotherapy (control)
Device · Drug
Lead sponsor
Medifocus, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
238 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Conditions
Long COVID
Interventions
Heat therapy, Sham Control, Walking
Behavioral
Lead sponsor
University of Nebraska
Other
Eligibility
50 Years to 90 Years
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Omaha, Nebraska
Conditions
Hypothermia
Interventions
placement of plastic cap during delivery room stabilization, placement of routine cap during delivery room stabilization
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
Up to 1 Hour
Enrollment
260 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Dallas, Texas
Conditions
Hypertension, Pure Autonomic Failure, Multiple System Atrophy, Autonomic Failure
Interventions
Passive heat stress, Control (non-heating)
Other
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years to 80 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
Nashville, Tennessee
Conditions
Liver Neoplasms, Neoplasm Metastasis
Interventions
Isolated hepatic portal and arterial perfusion, Melphalan
Procedure · Drug
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
Not listed
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 2001
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Tonsillitis
Interventions
PEAK PlasmaBlade TnA, Traditional Electrosurgery with scalpel
Device
Lead sponsor
Medtronic Surgical Technologies
Industry
Eligibility
3 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
2
States / cities
Merced, California • San Diego, California
Completed Not applicable Interventional Accepts healthy volunteers

Acute Exercise With Overdressing

NCT07080853
Conditions
Heat Stress, Exertional, Heat Acclimation and Thermotolerance
Interventions
Exercise with Overdressing, Control Exercise
Other
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years to 45 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Natick, Massachusetts
Conditions
Major Depressive Disorder, Depression
Interventions
Cognitive Behavioral Therapy (CBT), Active Whole-Body Hyperthermia (Active WBH), Sham Whole-Body Hyperthermia (Sham WBH)
Behavioral · Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
San Francisco, California
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Identification of Critical Thermal Environments for Aged Adults

NCT04284397
Conditions
Aging
Interventions
Low dose ASA, Control
Drug · Other
Lead sponsor
Penn State University
Other
Eligibility
18 Years and older
Enrollment
190 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2027
U.S. locations
1
States / cities
University Park, Pennsylvania
Conditions
Obesity, Polycystic Ovary Syndrome, Prehypertension, PreDiabetes, Cardiovascular Risk Factor, Metabolic Syndrome
Interventions
Heat therapy
Behavioral
Lead sponsor
University of Oregon
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Eugene, Oregon