- Conditions
- Alcohol Use Disorder (AUD), Post Traumatic Stress Disorder (PTSD)
- Interventions
- Dexmedetomidine (DEX) for sublingual (SL) administration (BXCL501) - 40µg, Dexmedetomidine (DEX) for sublingual (SL) administration (BXCL501) - 80µg
- Drug
- Lead sponsor
- Pharmacotherapies for Alcohol and Substance Use Disorders Alliance
- Other
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- West Haven, Connecticut
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Showing 1–24
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matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Arsenic Poisoning
- Interventions
- Standard Treatment, Intensive Education
- Other · Behavioral
- Lead sponsor
- Johns Hopkins Bloomberg School of Public Health
- Other
- Eligibility
- 10 Years and older
- Enrollment
- 57 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2027
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Sexually Transmitted Diseases, Bacterial, Alcohol; Harmful Use
- Interventions
- Access to Game Plan app and 24-hour helpline
- Behavioral
- Lead sponsor
- Brown University
- Other
- Eligibility
- 18 Years and older · Male only
- Enrollment
- 314 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2025
- U.S. locations
- 1
- States / cities
- Providence, Rhode Island
- Conditions
- Heavy Drinking, Harmful; Use, Alcohol
- Interventions
- Behavioral Self-Management and Feedback, Behavioral Self-Management
- Behavioral
- Lead sponsor
- Yale University
- Other
- Eligibility
- 18 Years to 25 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2023
- U.S. locations
- 1
- States / cities
- New Haven, Connecticut
- Conditions
- Sexual Assault, Heavy Drinking
- Interventions
- Alc-ERDT
- Behavioral
- Lead sponsor
- University of Washington
- Other
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2019
- U.S. locations
- 1
- States / cities
- Seattle, Washington
- Conditions
- Binge Drinking, Heavy Drinking, Young Adult, Heavy Drinker
- Interventions
- Mindfulness-Based Treatment-Regulation of Craving, Cognitive-Based Therapy-Regulation of Craving
- Behavioral
- Lead sponsor
- Yale University
- Other
- Eligibility
- 18 Years to 26 Years
- Enrollment
- 177 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2027
- U.S. locations
- 2
- States / cities
- Berkeley, California • New Haven, Connecticut
- Conditions
- Alcohol Drinking, Alcohol Use Disorder, Trauma Injury, Alcohol Dependence, Alcohol Abuse
- Interventions
- Real iTBS to the dlPFC, Sham iTBS to the dlPFC
- Device
- Lead sponsor
- Wake Forest University Health Sciences
- Other
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 11 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2021
- U.S. locations
- 1
- States / cities
- Winston-Salem, North Carolina
- Conditions
- Alcohol; Use, Problem
- Interventions
- Seed DS-01 Daily Synbiotic
- Dietary Supplement
- Lead sponsor
- Brown University
- Other
- Eligibility
- 18 Years to 64 Years
- Enrollment
- 32 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2023
- U.S. locations
- 1
- States / cities
- Providence, Rhode Island
- Conditions
- Heavy Drinking, Driving Under the Influence, Riding With Driver Under the Influence
- Interventions
- Computer-facilitated Screening and Brief Intervention
- Behavioral
- Lead sponsor
- Boston Children's Hospital
- Other
- Eligibility
- 14 Years to 17 Years
- Enrollment
- 169 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2026
- U.S. locations
- 3
- States / cities
- Itasca, Illinois • Boston, Massachusetts • Philadelphia, Pennsylvania
- Conditions
- Alcohol Use Disorder
- Interventions
- Dutasteride Capsules, Placebo Capsules
- Drug
- Lead sponsor
- UConn Health
- Other
- Eligibility
- 35 Years to 70 Years
- Enrollment
- 180 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2024
- U.S. locations
- 1
- States / cities
- Farmington, Connecticut
- Conditions
- Alcohol Use Disorder
- Interventions
- Realtime fMRI Neurofeedback - Active, TMS - Active, Realtime fMRI Neurofeedback - Yoked Sham, TMS - Sham
- Behavioral · Device
- Lead sponsor
- Auburn University
- Other
- Eligibility
- 19 Years to 65 Years
- Enrollment
- 90 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Auburn, Alabama
- Conditions
- Drinking Heavy, Drinking Behavior, Drinking Excessive
- Interventions
- Motivational Enhancement Therapy and Strengths Based Case Management (MET/SBCM), Alcohol education brochure
- Behavioral · Other
- Lead sponsor
- University of California, Los Angeles
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 237 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2021
- U.S. locations
- 2
- States / cities
- Van Nuys, California • Wilmington, California
- Conditions
- Alcohol Abuse, Alcoholism
- Interventions
- Ondansetron, Placebo, BASICS Plus
- Drug · Behavioral
- Lead sponsor
- University of Maryland, Baltimore
- Other
- Eligibility
- 18 Years to 25 Years
- Enrollment
- 74 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2017
- U.S. locations
- 1
- States / cities
- Columbia, Maryland
- Conditions
- Alcohol Use Disorder
- Interventions
- Nimodipine, Placebo
- Drug
- Lead sponsor
- Yale University
- Other
- Eligibility
- 21 Years to 50 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2032
- U.S. locations
- 1
- States / cities
- New Haven, Connecticut
- Conditions
- Cigarette Smoking, Alcohol Use Disorders
- Interventions
- Varenicline, Prazosin, Placebo
- Drug
- Lead sponsor
- Yale University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 5 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 1
- States / cities
- New Haven, Connecticut
- Conditions
- Alcohol Use Disorder, Mild-Moderate Traumatic Brain Injury
- Interventions
- Personalized VR Alcohol Approach Bias Modification (ApBM) Condition, Sham Condition
- Behavioral
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 18 Years to 65 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Alcohol Abuse, Alcohol Dependence, Heavy Drinking Days
- Interventions
- Kudzu extract, Placebo, Medical Management
- Drug · Behavioral
- Lead sponsor
- Mclean Hospital
- Other
- Eligibility
- 21 Years to 60 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2014
- U.S. locations
- 1
- States / cities
- Belmont, Massachusetts
- Conditions
- Alcohol Associated Liver Disease, Heavy Drinking Behavior
- Interventions
- Alirocumab, Placebo
- Drug · Other
- Lead sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
- NIH
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2026
- U.S. locations
- 1
- States / cities
- Bethesda, Maryland
- Conditions
- Alcohol Drinking, Alcohol Intoxication, Alcoholism
- Interventions
- Brain stimulation with mindfulness-based relapse prevention
- Device
- Lead sponsor
- University of New Mexico
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 84 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2018
- U.S. locations
- 1
- States / cities
- Albuquerque, New Mexico
- Conditions
- Alcohol Abuse, Posttraumatic Stress Disorder
- Interventions
- Prazosin, Placebo medication
- Drug
- Lead sponsor
- Seattle Institute for Biomedical and Clinical Research
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2012
- U.S. locations
- 1
- States / cities
- Seattle, Washington
- Conditions
- Alcohol Use Disorder, Mild Traumatic Brain Injury
- Interventions
- VR-WMR-Only, Exercise-only, Active VR-WMR
- Behavioral
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2020
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Alcohol Drinking, Alcohol Use Disorder, Alcohol Intoxication, Alcohol; Harmful Use, Alcoholism, Binge Drinking
- Interventions
- Alcohol
- Drug
- Lead sponsor
- University of Illinois at Urbana-Champaign
- Other
- Eligibility
- 21 Years to 30 Years
- Enrollment
- 640 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2023
- U.S. locations
- 1
- States / cities
- Champaign, Illinois
- Conditions
- Smoking, Heavy Episodic Drinking
- Interventions
- Tobacco Status Project Intervention, Tobacco Status Project + Alcohol Intervention, nicotine patch
- Behavioral · Drug
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 18 Years to 25 Years
- Enrollment
- 179 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2019
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Reduction in Heavy Drinking in Patients With HIV
- Interventions
- Naltrexone, Placebo + Medication Management/Medication Coaching
- Drug · Other
- Lead sponsor
- Yale University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 51 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2017
- U.S. locations
- 2
- States / cities
- New Haven, Connecticut