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Showing 1–24 of 39 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Hemiplegic Stroke Clear all
Completed Not applicable Interventional

Optimizing Training in Severe Post-Stroke Walking Impairment

NCT04721860
View directory record Official record
Conditions
Stroke, Chronic Stroke, Walking, Difficulty, Gait, Hemiplegic
Interventions
Backward Locomotion Treadmill Training (BLTT), Forward Locomotion Treadmill Training (FLTT)
Behavioral
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years to 80 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Jul 22, 2026, 10:40 AM EDT
Completed No phase listed Observational

Evaluating Human-Machine Interfaces in a Robotic Thumb Orthosis

NCT01973426
View directory record Official record
Conditions
Hemiplegic Stroke, Hemiplegic Cerebral Palsy
Interventions
Isolated Orthosis for Thumb Actuation (IOTA)
Device
Lead sponsor
Wyss Institute at Harvard University
Other
Eligibility
7 Years to 16 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 8, 2020 · Synced Jul 22, 2026, 10:40 AM EDT
Completed Not applicable Interventional

Treatment of Hemiparetic Gait Impairments Using Telehealth With the Moterum iStride Solution™

NCT04434313
View directory record Official record
Conditions
Telemedicine, Gait, Hemiplegic, Gait Disorders, Neurologic, Stroke, Orthotic Devices, Gait Analysis
Interventions
Delivery of iStride™ device gait treatment using telemedicine
Device
Lead sponsor
Moterum Technologies, Inc.
Industry
Eligibility
21 Years to 80 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Sep 6, 2022 · Synced Jul 22, 2026, 10:40 AM EDT
Completed Not applicable Interventional Results available

Gait Training Combined With Behavioral Strategies for People With Stroke

NCT04546217
View directory record Official record
Conditions
Stroke, Gait, Hemiplegic, Behavior and Behavior Mechanisms
Interventions
Treadmill training + transfer package (TT+TP), Treadmill training (TT)
Combination Product · Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 21, 2024 · Synced Jul 22, 2026, 10:40 AM EDT
Active, not recruiting Not applicable Interventional

Implant for Walking After Stroke

NCT05740540
View directory record Official record
Conditions
Stroke, Hemiplegia, Gait, Hemiplegic
Interventions
IRS-8, IST 12 & IST 16
Device
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
21 Years to 75 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
2
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Jul 22, 2026, 10:40 AM EDT
Completed Not applicable Interventional

The Effects of Plantar Flexion Training in People With Chronic Stroke

NCT03548090
View directory record Official record
Conditions
Stroke, Hemiplegic Gait
Interventions
Skateboard exercise at an incline angle of 0 degrees and 50% body weight, Skateboard exercise at an incline angle of 5 degrees and 50% body weight, Skateboard exercise at an incline angle determined to be optimal in phase 1 (either 0 or 5 degrees) and 75% body weight, Skateboard exercise at an incline angle determined to be optimal in phase 1 (either 0 or 5 degrees) and 90% body weight, Control 4-week exercise intervention, Experimental 4-week exercise intervention, Over-ground multi-directional gait training, Home exercise
Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 30, 2021 · Synced Jul 22, 2026, 10:40 AM EDT
Completed Not applicable Interventional Results available

Randomized DB Controlled Trial of Botulinum Toxin A in Hemiplegic Shoulder Pain and Spasticity

NCT00661089
View directory record Official record
Conditions
Post-stroke Shoulder Pain and Spasticity
Interventions
Botulinum Toxin Type A - OnabotulinumtoxinA, Placebo (Saline)
Drug
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2010
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 12, 2020 · Synced Jul 22, 2026, 10:40 AM EDT
Terminated Phase 2 Interventional

Acupuncture in Stroke Rehabilitation

NCT00547690
View directory record Official record
Conditions
Stroke
Interventions
Acupuncture and Strengthening, Strengthening Alone
Other
Lead sponsor
Wen Liu, Ph.D.
Other
Eligibility
20 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jun 5, 2012 · Synced Jul 22, 2026, 10:40 AM EDT
Completed Not applicable Interventional Results available

Multimodal Treatment for Hemiplegic Shoulder Pain

NCT02893267
View directory record Official record
Conditions
Stroke, Shoulder Pain
Interventions
Peripheral Nerve Stimulation, Physical Therapy, Sham-PT, Sham-PNS
Device · Other
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
21 Years to 89 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
3
States / cities
Chicago, Illinois • Charlotte, North Carolina • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 21, 2025 · Synced Jul 22, 2026, 10:40 AM EDT
Recruiting No phase listed Observational

Focused Intensive Repeated Stepping During Inpatient Rehabilitation Poststroke - A Quality Improvement Project

NCT05393661
View directory record Official record
Conditions
Stroke, Acute, Gait, Hemiplegic
Interventions
inpatient physical therapy poststroke
Other
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 89 Years
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2030
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jul 14, 2025 · Synced Jul 22, 2026, 10:40 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Neural Operant Conditioning

NCT06113965
View directory record Official record
Conditions
Stroke, Chronic Stroke, Gait, Hemiplegic, Gait, Spastic, Walking, Difficulty
Interventions
Peripheral Nerve Stimulation
Device
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 9, 2025 · Synced Jul 22, 2026, 10:40 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Validation of an Obstacle Course Used in Patients With Muscle Tightness

NCT00776048
View directory record Official record
Conditions
Stroke, Traumatic Brain Injury, Multiple Sclerosis, Spasticity, Healthy Controls
Interventions
Not listed
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 23, 2010 · Synced Jul 22, 2026, 10:40 AM EDT
Active, not recruiting Not applicable Interventional

GaitBetter: Motor and Cognitive Training for Gait Rehabilitation and Falls Prevention in Stroke Survivors.

NCT04625127
View directory record Official record
Conditions
Stroke, Gait, Hemiplegic, Hemiplegia
Interventions
Treadmill gait training with GaitBetter, Treadmill gait training with GaitBetter + Standard of care, Standard of care
Device · Other
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 85 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Jul 22, 2026, 10:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Innovative Gait Biofeedback Strategies for Stroke Rehabilitation

NCT03466372
View directory record Official record
Conditions
Stroke, Cardiovascular, Gait, Hemiplegic
Interventions
biofeedback
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years to 90 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated May 13, 2019 · Synced Jul 22, 2026, 10:40 AM EDT
Completed Not applicable Interventional Results available

Electrical Stimulation for Hemiplegic Shoulder Pain

NCT01123382
View directory record Official record
Conditions
Stroke, Shoulder Pain
Interventions
Intramuscular Electrical Stimulator, Outpatient Therapy
Device · Other
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
21 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 22, 2018 · Synced Jul 22, 2026, 10:40 AM EDT
Not listed No phase listed Observational

Biomarkers of Independent Walking Post-Stroke

NCT05004389
View directory record Official record
Conditions
Stroke, Acute, Gait, Hemiplegic
Interventions
MRI, blood draw, Clinical assessments
Diagnostic Test · Other
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Mar 13, 2023 · Synced Jul 22, 2026, 10:40 AM EDT
Completed Not applicable Interventional

Understanding the Effects of Quantitatively-Prescribing Passive-Dynamic Ankle-Foot Orthosis Bending Stiffness for Individuals Post-Stroke

NCT04619043
View directory record Official record
Conditions
Gait, Hemiplegic
Interventions
Ankle Orthotic
Device
Lead sponsor
University of Delaware
Other
Eligibility
Not listed
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Sep 14, 2023 · Synced Jul 22, 2026, 10:40 AM EDT
Completed Not applicable Interventional Results available

Electrical Stimulation for the Treatment of Chronic Post-Stroke Shoulder Pain Using the Smartpatch System

NCT01847885
View directory record Official record
Conditions
Post-stroke Shoulder Pain, Hemiplegic Shoulder Pain
Interventions
Smartpatch Peripheral Nerve Stimulation (PNS) System
Device
Lead sponsor
SPR Therapeutics, Inc.
Industry
Eligibility
21 Years and older
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
5
States / cities
Chicago, Illinois • West Orange, New Jersey • New York, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 15, 2017 · Synced Jul 22, 2026, 10:40 AM EDT
Terminated Not applicable Interventional

StimRouter™ for Pain Management in Post-stroke Shoulder Pain

NCT03093935
View directory record Official record
Conditions
Chronic Pain, Hemiplegic Shoulder Pain
Interventions
StimRouter Neuromodulation System
Device
Lead sponsor
Bioness Inc
Industry
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
2
States / cities
Miami, Florida • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jan 5, 2021 · Synced Jul 22, 2026, 10:40 AM EDT
Completed Not applicable Interventional

Effectiveness of IVR Combined With Task-Specific Training on Hemiplegic Arm Function Following Stroke

NCT05728866
View directory record Official record
Conditions
Stroke
Interventions
VR immersive therapy
Procedure
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced Jul 22, 2026, 10:40 AM EDT
Completed Not applicable Interventional Results available

Electrical Stimulation for the Treatment of Post-Stroke Shoulder Pain

NCT01094301
View directory record Official record
Conditions
Shoulder Pain
Interventions
The SPR System
Device
Lead sponsor
SPR Therapeutics, Inc.
Industry
Eligibility
21 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2017
U.S. locations
4
States / cities
New York, New York • Charlotte, North Carolina • Cleveland, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 11, 2018 · Synced Jul 22, 2026, 10:40 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Reflex Excitability in Post-stroke Stiff-Knee Gait

NCT04947865
View directory record Official record
Conditions
Stroke, Chronic Stroke, Gait, Hemiplegic, Gait, Spastic, Gait Disorder, Sensorimotor, Gait Disorders, Neurologic, Walking, Difficulty
Interventions
Peripheral nerve stimulation, Commercial knee brace
Other · Device
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 18, 2025 · Synced Jul 22, 2026, 10:40 AM EDT
Completed Phase 2 Interventional

Strength Training Effectiveness Post-Stroke (STEPS)

NCT00389012
View directory record Official record
Conditions
Cerebrovascular Accident
Interventions
exercise therapy, walking rehabilitation
Procedure
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
3
States / cities
Downey, California • Los Angeles, California • Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 5, 2017 · Synced Jul 22, 2026, 10:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Bimanual Training in Children With Hemiplegia

NCT01413594
View directory record Official record
Conditions
Hemiplegia, Cerebral Palsy, Children
Interventions
HABIT
Behavioral
Lead sponsor
Teachers College, Columbia University
Other
Eligibility
18 Months to 16 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 18, 2021 · Synced Jul 22, 2026, 10:40 AM EDT