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Showing 1–24 of 484 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Herniation Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Comparison of a Bilateral TAP Block and Preperitoneal Instillation of Local Anesthetic for a Total Extraperitoneal (TEP) Repair

NCT02036983
View directory record Official record
Conditions
Bilateral Inguinal Hernia Repair
Interventions
Transversus abdominis plane block (TAP BLOCK), Instillation of surgical site with local anesthetic., Opioid IV medications (Control)
Procedure
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 80 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 5, 2018 · Synced Sep 5, 2026, 6:38 AM EDT
Active, not recruiting No phase listed Observational

Assessment of GORE® SYNECOR Biomaterial in Focused Patient Populations and Long-Term Application

NCT05094089
View directory record Official record
Conditions
Hernia, Ventral, Hernia Incisional, Hernia Incisional Ventral
Interventions
Hernia repair with mesh
Device
Lead sponsor
W.L.Gore & Associates
Industry
Eligibility
18 Years to 80 Years
Enrollment
320 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2030
U.S. locations
8
States / cities
Atlanta, Georgia • Boston, Massachusetts • Grand Rapids, Michigan + 5 more
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Sep 5, 2026, 6:38 AM EDT
Withdrawn Not applicable Interventional

Miromatrix Biological Mesh for Ventral Hernia Repair

NCT02408458
View directory record Official record
Conditions
Ventral Hernia
Interventions
MIROMESH®
Device
Lead sponsor
Miromatrix Medical Inc.
Industry
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
4
States / cities
Sarasota, Florida • Lexington, Kentucky • Hershey, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 2, 2017 · Synced Sep 5, 2026, 6:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

CT and Radiologist RCT

NCT03121131
View directory record Official record
Conditions
Hernia
Interventions
Clinical Exam Findings, Inaccurate Clinical Exam Findings, No clinical exam findings
Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 12, 2020 · Synced Sep 5, 2026, 6:38 AM EDT
Completed No phase listed Observational

Use of Strattice Mesh in Paraesophageal Hernia Surgery

NCT01678157
View directory record Official record
Conditions
Esophageal Hernia, Hernia, Esophageal, Hernia, Paraesophageal, Hiatal Hernia, Paraesophageal Hiatal Hernia, Sliding Esophageal Hernia, Sliding Hiatal Hernia
Interventions
Not listed
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 5, 2023 · Synced Sep 5, 2026, 6:38 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Does a Transabdominal Plane Block Decrease Patient Pain After Ventral Hernia Repair?

NCT02007096
View directory record Official record
Conditions
Ventral Hernia, Umbilical Hernia, Incisional Hernia, Postoperative Complications, Pain, Postoperative
Interventions
Transabdominal Plane Block, Non Transabdominal Plane Block
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
127 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 18, 2018 · Synced Sep 5, 2026, 6:38 AM EDT
Terminated Phase 3 Interventional

Type of Material in Repair of Congenital Diaphragmatic Hernia

NCT00257946
View directory record Official record
Conditions
Congenital Diaphragmatic Hernia
Interventions
Repair of CDH w/SIS Gold, Repair of CDH w/Alloderm
Procedure
Lead sponsor
Children's Mercy Hospital Kansas City
Other
Eligibility
Up to 2 Months
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 14, 2011 · Synced Sep 5, 2026, 6:38 AM EDT
Completed Not applicable Interventional

dHACM in Lumbar Decompression and Microdiscectomy Surgery

NCT02300909
View directory record Official record
Conditions
Scarring, Spinal Stenosis, Herniated Disc
Interventions
Lumbar Decompression Surgery, Microdiscectomy Surgery, Dehydrated Human Amnion/Chorion Membrane (dHACM)
Procedure · Other
Lead sponsor
MiMedx Group, Inc.
Industry
Eligibility
18 Years and older
Enrollment
143 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 22, 2018 · Synced Sep 5, 2026, 6:38 AM EDT
Completed No phase listed Observational

Pain and Quality of Life After Inguinal Hernia Repair

NCT04074200
View directory record Official record
Conditions
Inguinal Hernia
Interventions
Open Inguinal Hernia Repair, Laparoscopic Inguinal Hernia Repair, Robotic-Assisted Inguinal Hernia Repair
Procedure · Device
Lead sponsor
Intuitive Surgical
Industry
Eligibility
18 Years to 80 Years
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 2, 2024 · Synced Sep 5, 2026, 6:38 AM EDT
Completed Not applicable Interventional

Ultrasound-guided Rectus Sheath Block for Post-operative Pain Control Following Umbilical Hernia Repair

NCT00836134
View directory record Official record
Conditions
Pain
Interventions
rectus sheath block, local anesthetic infiltration
Procedure
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
1 Year to 17 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 11, 2014 · Synced Sep 5, 2026, 6:38 AM EDT
Completed Phase 4 Interventional Results available

Parastomal Reinforcement With Strattice

NCT00771407
View directory record Official record
Conditions
Parastomal Hernia
Interventions
Strattice Reconstructive Matrix, Standard ostomy creation
Device · Other
Lead sponsor
LifeCell
Industry
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
23
States / cities
Mobile, Alabama • Los Angeles, California • Orange, California + 19 more
Source: ClinicalTrials.gov public record
Updated Sep 27, 2015 · Synced Sep 5, 2026, 6:38 AM EDT
Recruiting Not applicable Interventional

Discogen for Low Back Pain

NCT06611397
View directory record Official record
Conditions
Disc Herniation
Interventions
Discogen Low pulsed ultrasound treatment, Discogen Sham Treatment
Device
Lead sponsor
Columbia University
Other
Eligibility
21 Years to 75 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Sep 5, 2026, 6:38 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Epidural Clonidine for Lumbosacral Radiculopathy

NCT00588354
View directory record Official record
Conditions
Lumbar and Other Intervertebral Disc Disorders With Radiculopathy
Interventions
Clonidine, Triamcinolone hexacetonide, Lidocaine HCl
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 10, 2012 · Synced Sep 5, 2026, 6:38 AM EDT
Recruiting Phase 1 Interventional

Reversing InGuinal Hernia Trial: The Evaluation of Sex Hormones to Reverse Inguinal Hernias in Males

NCT07604272
View directory record Official record
Conditions
Inguinal Hernia Unilateral, Inguinal Hernia Bilateral, Inguinal Hernia Without Obstruction or Gangrene, Inguinal Hernia, Without Mention of Obstruction or Gangrene
Interventions
Fulvestrant, Anastrozole (ARIMIDEX™)
Drug
Lead sponsor
Northwestern University
Other
Eligibility
50 Years and older · Male only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 2, 2026 · Synced Sep 5, 2026, 6:38 AM EDT
Completed Not applicable Interventional

Fetal Surgery for Moderate Left Sided Congenital Diaphragmatic Hernia.

NCT00763737
View directory record Official record
Conditions
Congenital Diaphragmatic Hernia, Fetal Surgery, Pulmonary Hypoplasia
Interventions
Fetoscopic Endoluminal Tracheal Occlusion
Procedure
Lead sponsor
University Hospital, Gasthuisberg
Other
Eligibility
18 Years and older · Female only
Enrollment
196 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2020
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 2, 2020 · Synced Sep 5, 2026, 6:38 AM EDT
Completed Not applicable Interventional Results available

Postoperative Activity Restrictions in Children

NCT04145895
View directory record Official record
Conditions
Pediatric Post-operative Time to Return to Full Activity
Interventions
Postoperative activity restrictions
Other
Lead sponsor
Corewell Health East
Other
Eligibility
Not listed
Enrollment
168 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
2
States / cities
Royal Oak, Michigan • Troy, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 23, 2024 · Synced Sep 5, 2026, 6:38 AM EDT
Completed Not applicable Interventional Results available

Study of Transverse Abdominis Plane (TAP) Block in Children Undergoing Hydrocelectomy and/or Hernia Repair Surgery

NCT01698268
View directory record Official record
Conditions
Hydrocele, Inguinal Hernia
Interventions
TAP block, Local Infiltration
Procedure
Lead sponsor
Kaveh Aslani, MD
Other
Eligibility
2 Years to 8 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 23, 2017 · Synced Sep 5, 2026, 6:38 AM EDT
Completed Not applicable Interventional

Laparoscopic Ventral Hernia Repair With Elastomeric Pain Pump

NCT00472134
View directory record Official record
Conditions
Hernia, Ventral
Interventions
bupivacaine, On-Q PainBuster pump
Drug · Device
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 7, 2015 · Synced Sep 5, 2026, 6:38 AM EDT
Not listed No phase listed Observational

Natural Orifice Translumenal Endoscopic Surgery (NOTES): Laparoscopic Assisted Transvaginal Ventral Hernia Repair

NCT01398215
View directory record Official record
Conditions
Umbilical Hernia, Ventral Hernia
Interventions
transvaginal NOTES ventral hernia repair
Procedure
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2019
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 30, 2018 · Synced Sep 5, 2026, 6:38 AM EDT
Completed Phase 3 Interventional

The Value of Traction in the Treatment of Cervical Radiculopathy

NCT00979108
View directory record Official record
Conditions
Radiculopathy, Neck Pain, Spinal Diseases, Musculoskeletal Diseases, Neuromuscular Diseases, Intervertebral Disk Displacement
Interventions
Physical therapy rehabilitation
Other
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
18 Years to 70 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
2
States / cities
Lackland Air Force Base, Texas • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Nov 16, 2014 · Synced Sep 5, 2026, 6:38 AM EDT
Completed No phase listed Observational

Dominican Republic Mission Cost Analysis

NCT01872364
View directory record Official record
Conditions
Hernia, Hydrocele
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
Not listed
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 16, 2013 · Synced Sep 5, 2026, 6:38 AM EDT
Not listed Not applicable Interventional

Prospective Study Investigating Aspirin and Intraoperative Blood Loss and Complications Following Inguinal Hernia Repair

NCT02084615
View directory record Official record
Conditions
Hernia, Inguinal, Postoperative Complications, Postoperative Hemorrhage
Interventions
Aspirin
Drug
Lead sponsor
Jesse Brown VA Medical Center
Federal
Eligibility
18 Years and older · Male only
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 17, 2015 · Synced Sep 5, 2026, 6:38 AM EDT
Terminated Not applicable Interventional Results available

Dexamethasone Versus Depo Medrol in Lumbar Epidurals

NCT01397552
View directory record Official record
Conditions
Lumbar Spine Disc Herniation, Lumbar Radiculitis, Lumbar Back Pain
Interventions
Dexamethasone, methylprednisolone acetate
Drug
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
21 Years to 89 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
East Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Nov 21, 2023 · Synced Sep 5, 2026, 6:38 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Cytokine Response to Abdominal Wall Reconstruction

NCT07422584
View directory record Official record
Conditions
Incisional Ventral Hernia
Interventions
Not applicable- observational study
Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 19, 2026 · Synced Sep 5, 2026, 6:38 AM EDT