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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Herniation Clear all
Completed No phase listed Observational

Restorelle® Mesh Versus Native Tissue Repair for Prolapse

NCT02162615
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Restorelle Direct Fix A, Restorelle Direct Fix P, Native Tissue Repair Anterior, Native Tissue Repair Posterior
Device · Procedure
Lead sponsor
Coloplast A/S
Industry
Eligibility
18 Years and older · Female only
Enrollment
810 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
33
States / cities
Agoura Hills, California • Stanford, California • Denver, Colorado + 30 more
Source: ClinicalTrials.gov public record
Updated Jan 26, 2022 · Synced Jun 26, 2026, 9:23 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Mesh Removal Versus No Mesh Removal for Chronic Groin Pain After Inguinal Hernia Repair

NCT05484635
View directory record Official record
Conditions
Chronic Groin Pain, Hernia, Inguinal
Interventions
Diagnostic laparoscopy and inguinal mesh removal, Diagnostic laparoscopy
Procedure
Lead sponsor
David Krpata
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 5, 2025 · Synced Jun 26, 2026, 9:23 AM EDT
Completed No phase listed Observational

Assuring and Defining Outcomes Through Procedural Training Using a Proctorship Model That Collects Patient Outcomes A Single-Arm, Case-Series to Determine the Feasibility of Safe Skills Transfer for Laparoscopic Ventral Hernia Repair Utilizing a Hands-On Proctorship Model.

NCT02238743
View directory record Official record
Conditions
Hernia
Interventions
Not listed
Lead sponsor
Medtronic - MITG
Industry
Eligibility
Not listed
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 25, 2016 · Synced Jun 26, 2026, 9:23 AM EDT
Terminated Phase 4 Interventional Results available

Percutaneous HydroDiscectomy Compared to TESI for Radiculopathy

NCT02414698
View directory record Official record
Conditions
Lumbar Herniated Disc
Interventions
Percutaneous Hydrodiscectomy, TESI
Procedure · Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Mar 1, 2020 · Synced Jun 26, 2026, 9:23 AM EDT
Recruiting Phase 4 Interventional

Subjective Intraoperative Use of Epidural Steroid Administration Following Discectomy

NCT04182997
View directory record Official record
Conditions
Lumbar Disc Herniation
Interventions
Dexamethasone, saline 0.9%
Drug
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Jun 26, 2026, 9:23 AM EDT
Completed Phase 3 Interventional

Does Tension-Free Herniorrhaphy or Laparoscopic Herniorrhaphy Achieve Equal or Better Recurrence Rates and Lower Costs While Achieving Equivalent Outcomes for Hernia Patients?

NCT00032448
View directory record Official record
Conditions
Hernia
Interventions
Standardized tension-free herniorrhaphy with prosthesis
Procedure
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older · Male only
Enrollment
2,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2004
U.S. locations
14
States / cities
Birmingham, Alabama • No. Little Rock, Arkansas • San Francisco, California + 11 more
Source: ClinicalTrials.gov public record
Updated Apr 13, 2011 · Synced Jun 26, 2026, 9:23 AM EDT
Completed Not applicable Interventional Results available

Study of Transverse Abdominis Plane (TAP) Block in Children Undergoing Hydrocelectomy and/or Hernia Repair Surgery

NCT01698268
View directory record Official record
Conditions
Hydrocele, Inguinal Hernia
Interventions
TAP block, Local Infiltration
Procedure
Lead sponsor
Kaveh Aslani, MD
Other
Eligibility
2 Years to 8 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 23, 2017 · Synced Jun 26, 2026, 9:23 AM EDT
Completed Not applicable Interventional Results available

Percutaneous Rectus Sheath Block Versus Intra-operative Rectus Sheath Block for Pediatric Umbilical Hernia Repair

NCT02341144
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Pre-op percutaneous rectus sheath block, Intra-operative rectus sheath block, Ropivacaine
Procedure · Drug
Lead sponsor
Johns Hopkins All Children's Hospital
Other
Eligibility
3 Years to 18 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
St. Petersburg, Florida
Source: ClinicalTrials.gov public record
Updated Jul 2, 2023 · Synced Jun 26, 2026, 9:23 AM EDT
Active, not recruiting Phase 2 Interventional

Treatment of Occult Inguinal Hernias

NCT04815707
View directory record Official record
Conditions
Inguinal Hernia
Interventions
Occcult hernia repair
Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
252 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Jun 26, 2026, 9:23 AM EDT
Completed No phase listed Observational

Flexible Composite Next Generation Tissue Separating Mesh in Laparoscopic Incisional/Ventral Hernia Repair

NCT01162564
View directory record Official record
Conditions
Incisional Hernia, Ventral Hernia
Interventions
NG-TSM
Device
Lead sponsor
Ethicon, Inc.
Industry
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
6
States / cities
Jefferson City, Missouri • St Louis, Missouri • The Bronx, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Apr 26, 2011 · Synced Jun 26, 2026, 9:23 AM EDT
Completed Phase 3 Interventional Results available

Reducing INfection at the Surgical SitE With Antibiotic Irrigation During Ventral Hernia Repair (RINSE Trial)

NCT03945357
View directory record Official record
Conditions
Ventral Hernia Repair
Interventions
Gemcitabine/ clindamycin, Normal saline
Drug
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 23, 2023 · Synced Jun 26, 2026, 9:23 AM EDT
Recruiting Not applicable Interventional

Fetoscopic Endoluminal Tracheal Occlusion

NCT03674372
View directory record Official record
Conditions
Congenital Diaphragmatic Hernia
Interventions
Fetoscopic Endoluminal Tracheal Occlusion (FETO)
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older · Female only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2030
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 9, 2025 · Synced Jun 26, 2026, 9:23 AM EDT
Active, not recruiting Not applicable Interventional

AFFIX: Post-market Study of MaxTack™ Motorized Fixation Device in Subjects Undergoing Ventral Hernia Repair

NCT06710795
View directory record Official record
Conditions
Ventral Hernia
Interventions
MaxTack™ Motorized Fixation Device
Device
Lead sponsor
Medtronic - MITG
Industry
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
3
States / cities
Weston, Florida • Cleveland, Ohio • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Jun 26, 2026, 9:23 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Pilot Trial of Fetoscopic Endoluminal Tracheal Occlusion (FETO) in Severe Left Congenital Diaphragmatic Hernia (CDH)

NCT04583644
View directory record Official record
Conditions
Congenital Diaphragmatic Hernia
Interventions
Fetoscopic Endoluminal Tracheal Occlusion Surgery
Device
Lead sponsor
Hanmin Lee
Other
Eligibility
18 Years and older · Female only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2028
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced Jun 26, 2026, 9:23 AM EDT
Recruiting Not applicable Interventional

North American Fetal Therapy Network for Long-term Outcome Following Fetoscopic Endoluminal Tracheal Occlusion in Severe Left and Right Congenital Diaphragmatic Hernia

NCT06739356
View directory record Official record
Conditions
Congenital Diaphragmatic Hernia
Interventions
Fetal Treatment arm (FETO Group)
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older · Female only
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2031
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 18, 2025 · Synced Jun 26, 2026, 9:23 AM EDT
Completed Phase 4 Interventional Results available

EXPAREL Infiltrated Into the TAP for Postoperative Analgesia in Unilateral Abdominal Hernia Repair

NCT01801124
View directory record Official record
Conditions
Hernia
Interventions
EXPAREL
Drug
Lead sponsor
Pacira Pharmaceuticals, Inc
Industry
Eligibility
18 Years to 75 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Mar 7, 2021 · Synced Jun 26, 2026, 9:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparing eTEP and Laparoscopic Intraperitoneal Onlay Mesh (IPOM) for Ventral Hernias

NCT04150796
View directory record Official record
Conditions
Ventral Hernia, Umbilical Hernia, Epigastric Hernia
Interventions
Ventral Hernia Repair
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 3, 2023 · Synced Jun 26, 2026, 9:23 AM EDT
Active, not recruiting Not applicable Interventional

Fetoscopic Endoluminal Tracheal Occlusion (FETO) for Severe Left Diaphragmatic Hernia (CDH)

NCT02710968
View directory record Official record
Conditions
Congenital Diaphragmatic Hernia
Interventions
11540KE and Balt Goldbal 2 balloon
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older · Female only
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 9, 2025 · Synced Jun 26, 2026, 9:23 AM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Impact of Quadratus Lumborum Block on Recovery Profile After Ventral Hernia Repair

NCT03794882
View directory record Official record
Conditions
Pain, Postoperative, Opioid Use
Interventions
Quadratus Lumborum Block, Standard Medical Management
Combination Product · Procedure
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 80 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 20, 2022 · Synced Jun 26, 2026, 9:23 AM EDT
Completed Not applicable Interventional

The Role of the Robotic Platform in Inguinal Hernia Repair Surgery

NCT02816658
View directory record Official record
Conditions
Hernia, Inguinal
Interventions
Laparoscopic Inguinal Hernia Repair, Robotic Inguinal Hernia Repair
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
21 Years and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
6
States / cities
St Louis, Missouri • New York, New York • Wilmington, North Carolina + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 31, 2022 · Synced Jun 26, 2026, 9:23 AM EDT
Not listed No phase listed Observational

Assess the Efficacy of Prevena Plus vs SOC to Closed Incision in Pts Undergoing CAWR and Other Laparotomy Procedures.

NCT04539015
View directory record Official record
Conditions
Hernia
Interventions
Prevena Plus
Device
Lead sponsor
New York Medical College
Other
Eligibility
18 Years and older
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Valhalla, New York
Source: ClinicalTrials.gov public record
Updated Sep 3, 2020 · Synced Jun 26, 2026, 9:23 AM EDT
Not listed Not applicable Interventional

Preventing Opioid Misuse Through Safe Opioid Use Agreements Between Patients and Surgical Providers

NCT06167759
View directory record Official record
Conditions
Opioid Use, Inguinal Hernia, Ventral Hernia
Interventions
Opioid Use Agreement
Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
3
States / cities
Bellaire, Texas • Houston, Texas • Sugar Land, Texas
Source: ClinicalTrials.gov public record
Updated Dec 11, 2023 · Synced Jun 26, 2026, 9:23 AM EDT
Recruiting Phase 2 Interventional

A Trial of Phosphodiesterase-5 Inhibitor in Neonatal Congenital Diaphragmatic Hernia (TOP-CDH)

NCT05201144
View directory record Official record
Conditions
Congenital Diaphragmatic Hernia, Pulmonary Hypertension
Interventions
Sildenafil Oral Suspension, Placebo
Drug · Other
Lead sponsor
University of Utah
Other
Eligibility
Not listed
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 3, 2025 · Synced Jun 26, 2026, 9:23 AM EDT
Completed Phase 3 Interventional

Neurosurgery Patient Outcomes in Treating Spinal Disorders

NCT01220921
View directory record Official record
Conditions
Symptomatic Lumbar Disc Herniation, Symptomatic Grade I Lumbar Spondylolisthesis
Interventions
Lumbar Discectomy, Single-level lumbar fusion
Procedure
Lead sponsor
Greenwich Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
198 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
12
States / cities
San Francisco, California • Greenwich, Connecticut • New Haven, Connecticut + 9 more
Source: ClinicalTrials.gov public record
Updated Dec 3, 2015 · Synced Jun 26, 2026, 9:23 AM EDT