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Showing 1–24 of 121 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: High Intensity Exercise Clear all
Completed Not applicable Interventional

High Intensity Exercise for Increasing Fitness in Patients With Hypertrophic Cardiomyopathy

NCT03335332
View directory record Official record
Conditions
Hypertrophic Cardiomyopathy
Interventions
High intensity exercise, Moderate intensity exercise
Behavioral
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Feb 27, 2023 · Synced Jun 26, 2026, 6:18 AM EDT
Recruiting Not applicable Interventional

HIT-Stroke Trial 2

NCT06268041
View directory record Official record
Conditions
Stroke
Interventions
Moderate-Intensity Aerobic Training, High-Intensity Interval Training
Behavioral
Lead sponsor
University of Cincinnati
Other
Eligibility
30 Years to 85 Years
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
3
States / cities
Newark, Delaware • Kansas City, Kansas • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Jun 26, 2026, 6:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

"Facemask Use During High-intensity Interval Exercise in Temperate and Hot Environments"

NCT05143801
View directory record Official record
Conditions
Hypoxemia, Physiological Stress
Interventions
High-intensity interval exercise with surgical face mask in a temperate environment, High-intensity interval exercise with surgical face mask in a hot environment, High-intensity interval exercise without using a surgical face mask in a hot environment, High-intensity interval exercise without using a surgical face mask in a temperate environment
Device · Other
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Apr 24, 2022 · Synced Jun 26, 2026, 6:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Guayusa Extract on Exercise Training

NCT05820399
View directory record Official record
Conditions
Desire to Exercise, Exercise Training, Physical Exertion
Interventions
Organic Guayusa Extract, Placebo
Dietary Supplement
Lead sponsor
Nathaniel Jenkins
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Apr 18, 2023 · Synced Jun 26, 2026, 6:18 AM EDT
Recruiting Not applicable Interventional

High-Intensity Exercise to Combat Vascular and Cognitive Dysfunction in Adults With HIV

NCT05965518
View directory record Official record
Conditions
HIV, Arterial Stiffness, Cognitive Dysfunction
Interventions
High-Intensity Interval Training, Continuous Moderate Exercise
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
50 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 7, 2025 · Synced Jun 26, 2026, 6:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Molecular Markers of Neuroplasticity During Exercise in People With Incomplete Spinal Cord Injury

NCT01538693
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
escitalopram oxalate, Cyproheptadine, sugar pill, Graded intensity exercise
Drug · Other
Lead sponsor
T. George Hornby
Other
Eligibility
18 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 18, 2015 · Synced Jun 26, 2026, 6:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of High-Intensity Interval Training (HIT) While in a Hyperoxic-Hyperbaric Environment on Exercise Performance

NCT02941939
View directory record Official record
Conditions
Exercise Performance
Interventions
Hyperbaric chamber, Ambient pressure
Other
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
18 Years to 40 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Murray, Utah
Source: ClinicalTrials.gov public record
Updated May 21, 2018 · Synced Jun 26, 2026, 6:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The First 20 Fire Academy Recruits Exercise Training Program

NCT03319394
View directory record Official record
Conditions
Physical Fitness
Interventions
The First Twenty, Comparison
Behavioral
Lead sponsor
Kansas State University
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Manhattan, Kansas
Source: ClinicalTrials.gov public record
Updated Oct 23, 2017 · Synced Jun 26, 2026, 6:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Exercise on Chocolate Addiction

NCT03356509
View directory record Official record
Conditions
Acute Exercise and Addictive Behavior
Interventions
Exercise
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 45 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Coral Gables, Florida
Source: ClinicalTrials.gov public record
Updated Sep 17, 2018 · Synced Jun 26, 2026, 6:18 AM EDT
Completed Not applicable Interventional Results available

High Intensity Interval Training in Endometrial Cancer

NCT04025229
View directory record Official record
Conditions
Endometrial Cancer
Interventions
HIIT exercise
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Jun 26, 2026, 6:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

T Cell Responses to Various Levels of Exercise Stress

NCT06638684
View directory record Official record
Conditions
Healthy
Interventions
Exercise
Other
Lead sponsor
University of Kansas
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Lawrence, Kansas
Source: ClinicalTrials.gov public record
Updated Oct 14, 2024 · Synced Jun 26, 2026, 6:18 AM EDT
Not listed Not applicable Interventional

Priming Motor Learning Through Exercise in People With Spinocerebellar Ataxia

NCT05826171
View directory record Official record
Conditions
Spinocerebellar Ataxia Type 1, Spinocerebellar Ataxia Type 2, Spinocerebellar Ataxia Type 3, Spinocerebellar Ataxia Type 6, Spinocerebellar Ataxia Type 7
Interventions
High-Intensity Aerobic Exercise Prior to Balance Training, Low-Intensity Exercise Prior to Balance Training
Behavioral
Lead sponsor
Teachers College, Columbia University
Other
Eligibility
18 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 2, 2024 · Synced Jun 26, 2026, 6:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Physical Activity Variety's Impact on Physical Activity Participation

NCT05930431
View directory record Official record
Conditions
Physical Inactivity
Interventions
Physical activity variety intervention, Physical activity consistency comparison condition
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 25 Years · Male only
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 6, 2025 · Synced Jun 26, 2026, 6:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Changes in Intrahepatic Lipids With Exercise

NCT02181270
View directory record Official record
Conditions
Obese
Interventions
high intensity exercise, continuous moderate exercise
Other
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
21 Years to 60 Years
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 22, 2018 · Synced Jun 26, 2026, 6:18 AM EDT
Not yet recruiting Not applicable Interventional

Development and Efficacy of a Novel, Cost-Effective Gait Training Device Utilized at Home for Stroke Survivors

NCT07250425
View directory record Official record
Conditions
Stroke, Neurological Diseases or Conditions, Hemiparesis;Poststroke/CVA, Gait Disorders, Neurologic, Post Stroke Fatigue, Motor Recovery, Walking Difficulty, Balance Impairment, Falls Prevention, Hemiparesis, Mobility Limitation
Interventions
Rise&Walk InHome by Healing Innovations
Device
Lead sponsor
Healing Innovations
Other
Eligibility
18 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 8, 2026 · Synced Jun 26, 2026, 6:18 AM EDT
Recruiting Not applicable Interventional

C.A.P.A.B.L.E. (CrossFit® and Physical Activity: A Better Life Experience)

NCT03750981
View directory record Official record
Conditions
Cancer Survivors
Interventions
12 week pilot intervention study.
Behavioral
Lead sponsor
Barbara Ann Karmanos Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2028
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 5, 2025 · Synced Jun 26, 2026, 6:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Acute Renal Injury During High Intensity Training

NCT03678285
View directory record Official record
Conditions
Acute Kidney Injury, Exercise
Interventions
HIFRT Workout
Other
Lead sponsor
University of Wyoming
Other
Eligibility
18 Years to 60 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Laramie, Wyoming
Source: ClinicalTrials.gov public record
Updated Jul 15, 2021 · Synced Jun 26, 2026, 6:18 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Nicotinamide Mononucleotide Supplementation for Exercise Tolerance Improvement in Healthy Older Adults

NCT07144527
View directory record Official record
Conditions
Aging, Frailty, Exercise Tolerance, Healthy Male and Female Subjects
Interventions
NMN, betaine, low-dose hydrogen peroxide (EGA), Nicotinamide Mononucleotide (NMN), Placebo
Dietary Supplement
Lead sponsor
Scott Silveira
Other
Eligibility
60 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Beverly Hills, California
Source: ClinicalTrials.gov public record
Updated Feb 19, 2026 · Synced Jun 26, 2026, 6:18 AM EDT
Completed Not applicable Interventional

High-Intensity Aerobic Lifelong Training--AF

NCT03241433
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
High intensity interval training, Moderate intensity continuous training, No Exercise
Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 19, 2019 · Synced Jun 26, 2026, 6:18 AM EDT
Completed Not applicable Interventional

High-intensity Interval Circuit Training in People With Parkinson Disease

NCT06576817
View directory record Official record
Conditions
Parkinson Disease
Interventions
High intensity circuit exercise class - Lower and upper extremity, High intensity circuit exercise class - Lower extremity alone
Other
Lead sponsor
Pacific Northwest University of Health Sciences
Other
Eligibility
Not listed
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Yakima, Washington
Source: ClinicalTrials.gov public record
Updated Mar 26, 2026 · Synced Jun 26, 2026, 6:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

CASH- Children Active to Stay Healthy

NCT01821313
View directory record Official record
Conditions
Childhood Obesity, Inflammation
Interventions
Moderate exercise, High Intensity Interval Exercise
Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
13 Years to 17 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 23, 2015 · Synced Jun 26, 2026, 6:18 AM EDT
Recruiting Phase 1Phase 2 Interventional Accepts healthy volunteers

Classroom Break, Cognition, and Fitness in Elementary School Children

NCT06258941
View directory record Official record
Conditions
Healthy Volunteers
Interventions
MF-HIIT, HIIT-only, MF-only, Sedentary activity
Behavioral
Lead sponsor
Purdue University
Other
Eligibility
8 Years to 12 Years
Enrollment
352 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Royal Center, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Jun 26, 2026, 6:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The HIIT Cognition Study

NCT05137990
View directory record Official record
Conditions
High Intensity Interval Training, Overweight and Obesity, Metabolic Disease, Cognition
Interventions
HIIT Exercise Intervention, Stretching Intervention
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
12 Years to 16 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 6, 2024 · Synced Jun 26, 2026, 6:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

High-Intensity Exercise in Older Adults

NCT06199661
View directory record Official record
Conditions
Functional Fitness, Cognitive Abilities
Interventions
APEX
Behavioral
Lead sponsor
University of California, Berkeley
Other
Eligibility
50 Years to 80 Years
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 9, 2024 · Synced Jun 26, 2026, 6:18 AM EDT