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Showing 1–22 of 22 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: High Risk Drinking Clear all
Recruiting Not applicable Interventional

Reset Challenge: Reducing High-risk Drinking for Cancer Prevention

NCT07591428
View directory record Official record
Conditions
Alcohol Drinking, Heavy Drinking, Binge Drinking
Interventions
30-Day Alcohol Abstinence Challenge
Behavioral
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 120 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Jul 22, 2026, 9:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

REAL Parenting Alcohol and Substance Use App

NCT03932097
View directory record Official record
Conditions
Underage Drinking, Alcohol Use, Underage
Interventions
REAL Parenting, Active Control Materials
Behavioral · Other
Lead sponsor
Real Prevention, LLC
Industry
Eligibility
15 Years to 18 Years
Enrollment
306 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Clifton, New Jersey
Source: ClinicalTrials.gov public record
Updated May 24, 2023 · Synced Jul 22, 2026, 9:40 AM EDT
Completed Not applicable Interventional

Mobile Alcohol Use Intervention

NCT07126613
View directory record Official record
Conditions
Alcohol Misuse
Interventions
Mobile Health Intervention to Reduce Alcohol Use Among Young Adults
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 25 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Jul 22, 2026, 9:40 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Game Plan: Efficacy of a Brief, Web-based Intervention on Alcohol Use and Sexually-transmitted Infections

NCT04552171
View directory record Official record
Conditions
Sexually Transmitted Diseases, Bacterial, Alcohol; Harmful Use
Interventions
Access to Game Plan app and 24-hour helpline
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older · Male only
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 6, 2025 · Synced Jul 22, 2026, 9:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Computerized Brief Alcohol Intervention (BI) for Binge Drinking HIV At-Risk and Infected Women

NCT01125371
View directory record Official record
Conditions
Alcohol; Harmful Use, Binge Drinking, Risk Behavior, HIV Infection
Interventions
Computerized brief alcohol intervention + IVR booster calls, Computerized brief alcohol intervention, Attention Control
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 90 Years · Female only
Enrollment
439 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 23, 2022 · Synced Jul 22, 2026, 9:40 AM EDT
Not yet recruiting Not applicable Interventional

Social Media Intervention for Risky Drinking

NCT07251192
View directory record Official record
Conditions
Drinking Behavior
Interventions
Social media messaging
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 25 Years
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Jul 22, 2026, 9:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Native-Changing High-risk Alcohol Use and Increasing Contraception Effectiveness Study

NCT03930342
View directory record Official record
Conditions
Contraceptive Usage, Alcohol Use Complicating Childbirth, Alcohol Drinking
Interventions
Native-CHOICES
Behavioral
Lead sponsor
Washington State University
Other
Eligibility
18 Years to 44 Years · Female only
Enrollment
404 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
2
States / cities
Eagle Butte, South Dakota • Rapid City, South Dakota
Source: ClinicalTrials.gov public record
Updated Apr 16, 2025 · Synced Jul 22, 2026, 9:40 AM EDT
Completed Not applicable Interventional Results available

A Social Media Intervention for Risky Drinking

NCT04721925
View directory record Official record
Conditions
Drinking Behavior
Interventions
Social media messaging
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 25 Years
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 2, 2023 · Synced Jul 22, 2026, 9:40 AM EDT
Recruiting Phase 3 Interventional

Intervention to Increase Intention to Change Alcohol/Tobacco Use in Veterans With Chronic Disease

NCT07039175
View directory record Official record
Conditions
Tobacco Smoking, Alcohol-Related Disorders
Interventions
MINDSET, Usual Care
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Dec 30, 2025 · Synced Jul 22, 2026, 9:40 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Narrative Writing to Promote Healthy Decisions About Alcohol During the Transition Out of High School

NCT06191861
View directory record Official record
Conditions
Alcohol Use, Unspecified
Interventions
Most hoped for future self, Most feared future self, Control (trip to zoo), Balanced future self
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
17 Years to 19 Years
Enrollment
468 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Jul 22, 2026, 9:40 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Biomarker Feedback Intervention

NCT07307326
View directory record Official record
Conditions
High Risk Drinking, College Student Drinking
Interventions
eCHECKUP TO GO (eCTG), eCHECKUPTOGO + brief personalized alcohol biomarker feedback intervention (eCTG + TAC)
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
18 Years to 23 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Jul 22, 2026, 9:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Efficacy of a Web-Based Alcohol Intervention for High School Students

NCT03613818
View directory record Official record
Conditions
Underage Drinking
Interventions
eCHECKUP TO GO
Behavioral
Lead sponsor
Boise State University
Other
Eligibility
16 Years to 18 Years
Enrollment
311 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Boise, Idaho
Source: ClinicalTrials.gov public record
Updated Mar 31, 2021 · Synced Jul 22, 2026, 9:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A High School Program for Preventing Prescription Drug Misuse

NCT03219190
View directory record Official record
Conditions
Prescription Drug Abuse, Substance Abuse, Substance Use (Drugs, Alcohol)
Interventions
LST High School Hybrid
Behavioral
Lead sponsor
National Health Promotion Associates, Inc.
Industry
Eligibility
14 Years to 18 Years
Enrollment
1,804 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
White Plains, New York
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Jul 22, 2026, 9:40 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Examining an Intervention to Reduce High School Drinking

NCT07086508
View directory record Official record
Conditions
Underage Drinking, Drinking, Teen, Adolescent Alcohol Use
Interventions
e-CHECKUP TO GO (eCTG), e-Parent Intervention
Behavioral
Lead sponsor
Binghamton University
Other
Eligibility
15 Years to 18 Years
Enrollment
2,532 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Binghamton, New York
Source: ClinicalTrials.gov public record
Updated Jun 21, 2026 · Synced Jul 22, 2026, 9:40 AM EDT
Not listed Phase 2 Interventional

Project RAP: Reaching Adolescents for Prevention

NCT00183157
View directory record Official record
Conditions
Alcohol Related Morbidity, Alcohol Dependence
Interventions
Brief Motivational Intervention, Assessment and list of resources, Referral to Community Resources
Behavioral
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
14 Years to 21 Years
Enrollment
1,400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 12, 2009 · Synced Jul 22, 2026, 9:40 AM EDT
Completed Not applicable Interventional Results available

Family-focused vs. Drinker-focused Smartphone Interventions to Reduce Drinking-related Consequences of COVID-19

NCT05419128
View directory record Official record
Conditions
Alcohol Use Disorder, Family Members, Behavior, Addictive
Interventions
PartnerCHESS, ACHESS
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
398 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Jul 22, 2026, 9:40 AM EDT
Recruiting Not applicable Interventional

The GLUCID Study: Effect of Alcohol Reduction and Probiotic Interventions on Cognition and Brain Glucose Metabolism in Normal Aging Adults Who Are High-Risk Alcohol Drinkers

NCT07415707
View directory record Official record
Conditions
Aging, Alcohol Drinking
Interventions
Visbiome, Motivational Interviewing, Placebo
Dietary Supplement · Behavioral · Other
Lead sponsor
University of Miami
Other
Eligibility
65 Years to 84 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Jul 22, 2026, 9:40 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Reducing Blood Pressure in Mid-life Adult Binge Drinkers

NCT05522075
View directory record Official record
Conditions
Alcohol Drinking, Binge Drinking, Blood Pressure, Alcohol Abstinence, Aging, Lifestyle Factors, Vasodilation, Behavioral Problem
Interventions
Exercise Training, Alcohol Abstinence Intervention
Behavioral
Lead sponsor
The University of Texas at Arlington
Other
Eligibility
50 Years to 64 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Arlington, Texas
Source: ClinicalTrials.gov public record
Updated May 31, 2026 · Synced Jul 22, 2026, 9:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Game Plan for PrEP

NCT04973267
View directory record Official record
Conditions
Human Immunodeficiency Virus Exposure, Alcohol; Harmful Use
Interventions
Game Plan for PrEP, Attention-Matched Control Lifestyle Habits Videos
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older · Male only
Enrollment
73 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 27, 2024 · Synced Jul 22, 2026, 9:40 AM EDT
Completed Phase 2 Interventional

Evaluation of an School-based Alcohol Prevention Program for Middle School Students

NCT01847183
View directory record Official record
Conditions
Alcohol-related Disorders, Drinking and Driving, Neurological Impairment
Interventions
Click City®: Alcohol
Behavioral
Lead sponsor
Oregon Research Institute
Other
Eligibility
12 Years to 16 Years
Enrollment
2,300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 5, 2016 · Synced Jul 22, 2026, 9:40 AM EDT
Completed Phase 4 Interventional Results available

High Dose Vitamin B1 to Reduce Abusive Alcohol Use

NCT00680121
View directory record Official record
Conditions
Alcoholism
Interventions
Benfotiamine, Placebo
Drug
Lead sponsor
University of Kansas
Other
Eligibility
18 Years to 60 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Sep 24, 2014 · Synced Jul 22, 2026, 9:40 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Brief Mobile Intervention for Prepartying

NCT04016766
View directory record Official record
Conditions
Heavy Drinking
Interventions
Mobile app prepartying intervention
Behavioral
Lead sponsor
RAND
Other
Eligibility
18 Years to 24 Years
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 16, 2021 · Synced Jul 22, 2026, 9:40 AM EDT