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ClinicalTrials.gov public records Last synced Sep 10, 2026, 11:28 AM EDT

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Showing 1–24 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: High-frequency Stimulation Clear all
Recruiting No phase listed Observational

Neurostimulation for Treatment of Chronic Upper Limb Pain After Brachial Plexus Injury

NCT04733599
View directory record Official record
Conditions
Brachial Plexus Injury
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
2
States / cities
Jacksonville, Florida • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 1, 2026 · Synced Sep 10, 2026, 11:28 AM EDT
Not yet recruiting Not applicable Interventional

Acute Stimulation and Modulation of Stereotyped High-Frequency Oscillations

NCT06898138
View directory record Official record
Conditions
Epilepsy
Interventions
Brain Interchange System
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
3 Years to 70 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
2
States / cities
Rochester, Minnesota • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Sep 10, 2026, 11:28 AM EDT
Active, not recruiting Not applicable Interventional Results available

Comparing Long-term Effectiveness of High Frequency and Burst Spinal Cord Stimulation

NCT03681262
View directory record Official record
Conditions
Chronic Pain
Interventions
High frequency spinal cord stimulation, Burst spinal cord stimulation
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated May 12, 2026 · Synced Sep 10, 2026, 11:28 AM EDT
Recruiting Not applicable Interventional

High Frequency Light, Sound, and Tactile Stimulation to Improve Motor and Cognitive Deficits in Parkinson's Disease

NCT05268887
View directory record Official record
Conditions
Parkinson Disease
Interventions
GENUS device (Active Settings), GENUS device (Sham settings)
Device
Lead sponsor
Massachusetts Institute of Technology
Other
Eligibility
45 Years to 90 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Sep 10, 2026, 11:28 AM EDT
Active, not recruiting Phase 1 Interventional

Enhancing Gait Using Alternating-Frequency DBS in Parkinson Disease

NCT05022147
View directory record Official record
Conditions
Parkinson Disease, Gait Disorders, Neurologic, Disease Progression, Subthalamic Nucleus, Accidental Fall, Deep Brain Stimulation
Interventions
High-Frequency-Only Stimulation, Low-Frequency-Only Stimulation, Alternating, 50 sec High-Frequency, 10 sec Low-Frequency Stimulation, Alternating, 50 sec High-Frequency, 50 sec Low-Frequency Stimulation, Alternating, 10 sec High-Frequency, 50 sec Low-Frequency Stimulation, Alternating, 10 sec High-Frequency, 10 sec Low-Frequency Stimulation, OFF Dopaminergic Medication, ON Dopaminergic Medication
Device · Drug
Lead sponsor
James Liao
Other
Eligibility
21 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Sep 10, 2026, 11:28 AM EDT
Completed Not applicable Interventional Results available

Effect of Vibration Therapy on Bone in Persons With Sub-acute Spinal Cord Injury

NCT00886145
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Vibration: Right Leg and No Vibration: Left Leg.
Device
Lead sponsor
William A. Bauman, M.D.
Federal
Eligibility
18 Years to 65 Years · Male only
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Apr 27, 2016 · Synced Sep 10, 2026, 11:28 AM EDT
Completed Not applicable Interventional

BioWave High-frequency Neurostimulation Versus TENS for the Treatment of Chronic Low Back Pain

NCT05511181
View directory record Official record
Conditions
Chronic Pain, Lumbar Pain Syndrome, Low Back Pain
Interventions
BioWave, TENS
Device
Lead sponsor
BioWave Corporation
Industry
Eligibility
18 Years to 85 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
4
States / cities
New Haven, Connecticut • Huntersville, North Carolina • Lancaster, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 2, 2023 · Synced Sep 10, 2026, 11:28 AM EDT
Recruiting Not applicable Interventional

rTMS Over the Dorsolateral Prefrontal Cortex for the Treatment of Impulse Control Disorders in Parkinson's Disease

NCT06237868
View directory record Official record
Conditions
Impulse Control Disorder, Parkinson Disease
Interventions
rTMS Active, rTMS Sham
Device
Lead sponsor
West Virginia University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Apr 19, 2026 · Synced Sep 10, 2026, 11:28 AM EDT
Completed Early Phase 1 Interventional Results available

High Frequency SARS for Neurogenic Bladder and Bowel Emptying

NCT05214378
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Finetech-Brindley Sacral Anterior Roots Stimulation System
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
2
States / cities
Syracuse, New York • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 21, 2025 · Synced Sep 10, 2026, 11:28 AM EDT
Active, not recruiting Not applicable Interventional

High Frequency Light and Sound Stimulation to Improve Brain Functions in Alzheimer's Disease

NCT04042922
View directory record Official record
Conditions
Alzheimer Disease
Interventions
GENUS device (Active Settings), GENUS device (Sham Settings)
Device
Lead sponsor
Massachusetts Institute of Technology
Other
Eligibility
50 Years to 100 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 30, 2024 · Synced Sep 10, 2026, 11:28 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

High-Frequency Repetitive Transcranial Magnetic Stimulation of the Right Dorsolateral Prefrontal Cortex in PTSD

NCT02873299
View directory record Official record
Conditions
PTSD, Post Traumatic Stress Disorder
Interventions
10 Hz rTMS of the right dorsolateral prefrontal cortex, 20 Hz rTMS of the right dorsolateral prefrontal cortex
Other
Lead sponsor
United States Naval Medical Center, San Diego
Federal
Eligibility
18 Years to 65 Years
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 21, 2016 · Synced Sep 10, 2026, 11:28 AM EDT
Terminated Not applicable Interventional Results available

rTMS Combined With BWSTT in Stroke With Body Weight Supported Treadmill Training (BWSTT) After Stroke

NCT03441334
View directory record Official record
Conditions
Stroke
Interventions
High Frequency rTMS, Sham rTMS
Device
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years to 80 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 5, 2023 · Synced Sep 10, 2026, 11:28 AM EDT
Completed Not applicable Interventional Results available

Quantitative Assessment of Painful Diabetic Peripheral Neuropathy After High Frequency Spinal Cord Stimulation

NCT03769675
View directory record Official record
Conditions
Painful Diabetic Neuropathy
Interventions
High Frequency Spinal Cord Stimulator
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 10, 2023 · Synced Sep 10, 2026, 11:28 AM EDT
Recruiting No phase listed Observational

Intensive Multimodal Neurorehabilitation Targeting Neuroplasticity in Pediatric Neurodevelopmental and Chromosomal Disorders

NCT07493096
View directory record Official record
Conditions
Neurodevelopmental Disorders, Neurodevelopmental Disorders (NDD), Neurodevelopmental Disorders and Developmental Abnormalities, Developmental Delay (Disorder), Cerebral Palsy (CP), Cerebral Palsy Hemiparetic Cerebral Palsy Spasticity Gait Disorders, Neurologic Postural Balance Impairment, Cerebral Palsy Infantile, Cerebral Palsy Spastic Hemiplegic, Cerebral Palsy, Dyskinetic, Autism Spectrum Disorder, Autism Spectrum Disorder (ASD, Hypoxic Ischemic Encephalopathy, Hypoxic Ischemic Encephalopathy (HIE), Traumatic Brain Injury (TBI), Sensory Processing Disorder, Chromosomal Abnormalities, Genetic Disorders, Down Syndrome (Trisomy 21), Fragile X Syndrome (FXS), RETT Syndrome With Proven MECP2 Mutation, Williams Syndrome, 22q11.2 Deletion Syndrome, Sensorimotor Integration
Interventions
Not listed
Lead sponsor
Healing Hope International
Other
Eligibility
4 Years to 12 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2036
U.S. locations
1
States / cities
The Woodlands, Texas
Source: ClinicalTrials.gov public record
Updated Mar 24, 2026 · Synced Sep 10, 2026, 11:28 AM EDT
Completed Not applicable Interventional Results available

tACS for Amyloid-β Reduction in Alzheimer's Disease

NCT03290326
View directory record Official record
Conditions
Alzheimer Disease
Interventions
Transcranial Alternating Current Stimulation (tACS)
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
45 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 21, 2022 · Synced Sep 10, 2026, 11:28 AM EDT
Completed Not applicable Interventional Results available

Direct Comparison of Spinal Cord Stimulator Parameter Settings

NCT05283863
View directory record Official record
Conditions
Spinal Cord Stimulation, High-frequency Stimulation, High-density Stimulation
Interventions
High-frequency stimulation, Sham Stimulation
Device
Lead sponsor
Case Western Reserve University
Other
Eligibility
18 Years to 75 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 20, 2024 · Synced Sep 10, 2026, 11:28 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Feasibility Study for the Use of Low-magnitude, High Frequency Mechanical Stimulation of Bone in Persons With Spinal Cord Injury (SCI)

NCT00882843
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Not listed
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 80 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2010
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jun 24, 2012 · Synced Sep 10, 2026, 11:28 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

High Frequency Stimulation to Improve Cognition, Mobility, and Affect in Individuals With and Without Subjective Cognitive Decline

NCT07395609
View directory record Official record
Conditions
Subjective Cognitive Decline (SCD), Healthy Subjects
Interventions
Experimental -- 16.67 Hz Visual Occlusion, Control - 1Hz Visual Occlusion
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
65 Years to 89 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Sep 10, 2026, 11:28 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Outcomes in Children With Pre-operative Residual Hearing

NCT03379870
View directory record Official record
Conditions
High Frequency Sensorineural Hearing Impairment, Hearing Disorders in Children
Interventions
Electric Acoustic Speech Processor: Electric-acoustic stimulation fitting, Electric Acoustic Speech Processor: Full-electric stimulation fitting
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
60 Months to 215 Months
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 14, 2024 · Synced Sep 10, 2026, 11:28 AM EDT
Completed Not applicable Interventional Results available

Interactions of Fronto-Parietal High Frequency rTMS on Anterior Cingulate Cortex Activation in Schizophrenia

NCT04309370
View directory record Official record
Conditions
Schizophrenia
Interventions
20 Hz rTMS
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 40 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
2
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 2, 2023 · Synced Sep 10, 2026, 11:28 AM EDT
Completed Not applicable Interventional Results available

Transspinal Stimulation Plus Locomotor Training for SCI

NCT04807764
View directory record Official record
Conditions
Spinal Cord Injuries, Paraplegia, Spinal, Tetraplegia/Tetraparesis, Paraplegia, Spastic
Interventions
Standing transspinal stimulation followed by robotic gait training, Lying transspinal stimulation followed by robotic gait training, Standing sham transspinal stimulation followed by robotic gait training
Combination Product · Other
Lead sponsor
City University of New York
Other
Eligibility
18 Years to 70 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
2
States / cities
Staten Island, New York • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Sep 10, 2026, 11:28 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

High Frequency Stimulation Trials in Patients With Precision Spinal Cord Stimulator System

NCT02265848
View directory record Official record
Conditions
Chronic Pain, Low Back Pain, Radiculopathy, Complex Regional Pain Syndrome (CRPS)
Interventions
High frequency stimulation, Low frequency stimulation
Other
Lead sponsor
The Center for Clinical Research, Winston-Salem, NC
Other
Eligibility
18 Years to 70 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 24, 2016 · Synced Sep 10, 2026, 11:28 AM EDT
Recruiting Not applicable Interventional

Transvaginal Electrical Stimulation for Myofascial Pelvic Pain

NCT05354869
View directory record Official record
Conditions
Myofascial Pelvic Pain
Interventions
Urostym, Standard care
Device · Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Sep 10, 2026, 11:28 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Repetitive Transcranial Magnetic Stimulation on Motor Function and Meta-Plasticity in Cerebral Palsy: TMS-EEG Study

NCT07567053
View directory record Official record
Conditions
Cerebral Palsy, Typically Developing Children
Interventions
MRI, HD-EEG Recording, rTMS
Device
Lead sponsor
Cook Children's Health Care System
Other
Eligibility
6 Years to 20 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Sep 10, 2026, 11:28 AM EDT