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ClinicalTrials.gov public records Last synced Nov 14, 2026, 10:45 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 129 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: High-risk Sex Clear all

Conditions: HIV
Interventions: Relationship Strengthening HIV Prevention Intervention, Parenting Program Intervention; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 14 Years and older
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2020
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: HIV Preexposure Prophylaxis
Interventions: ISL, FTC/TDF, FTC/TAF, Placebo to ISL, Placebo to FTC/TDF, Placebo to FTC/TAF; Drug
Lead sponsor: Merck Sharp & Dohme LLC; Industry
Eligibility: 16 Years and older · Male only
Enrollment: 494 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 15
States / cities: Birmingham, Alabama • Los Angeles, California • San Francisco, California + 11 more

Conditions: Hpv, HPV 16 Infection, HPV Infection, High Risk HPV
Interventions: Teal Wand Self-Collection Device Group; Device
Lead sponsor: Teal Health, Inc.; Industry
Eligibility: 25 Years to 65 Years · Female only
Enrollment: 870 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 15
States / cities: Birmingham, Alabama • San Francisco, California • Aurora, Colorado + 10 more

Conditions: Help-Seeking Behavior, Pre-exposure Prophylaxis Use, Condomless Sex, Risky Health Behavior
Interventions: Moon and Sun Brothers: A Community Prevention Intervention; Behavioral
Lead sponsor: San Francisco State University; Other
Eligibility: 18 Years and older
Enrollment: 360 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2028
U.S. locations: 2
States / cities: San Francisco, California • Chicago, Illinois

Conditions: Substance Abuse, HIV Infections
Interventions: Aripiprazole, Placebo; Drug
Lead sponsor: San Francisco Department of Public Health; Government
Eligibility: 18 Years to 60 Years
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Unsafe Sex, Physical Violence, Sexual Assault, Sexual Abuse
Interventions: Nutrition Program (NP), Women's Prison CoOp (WPC); Behavioral
Lead sponsor: Brown University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 42 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 3
States / cities: Framingham, Massachusetts • Cranston, Rhode Island

Conditions: Anal High Grade Squamous Intraepithelial Lesion, Anal Precancerous Condition, AIN 2/3, HPV Infection, Anal Dysplasia, HPV Disease
Interventions: Artesunate, Placebo; Drug
Lead sponsor: Frantz Viral Therapeutics, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 2
States / cities: Chicago, Illinois • New York, New York

Conditions: HIV Infections, Sexually Transmitted Diseases
Interventions: Emtricitabine / Tenofovir; Drug
Lead sponsor: The Miriam Hospital; Other
Eligibility: 18 Years and older · Male only
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: HIV/AIDS, Pre-exposure Prophylaxis
Interventions: PrEP-LINK, Enhanced Standard of Care; Behavioral · Other
Lead sponsor: University of Arkansas; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2024
U.S. locations: 7
States / cities: Little Rock, Arkansas • West Memphis, Arkansas

Conditions: Alcohol Drinking, Sex, Unsafe, Hiv
Interventions: Self-Regulation Intervention, Brief Advice and Information; Behavioral
Lead sponsor: Boston University Charles River Campus; Other
Eligibility: 18 Years and older · Male only
Enrollment: 354 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Human Immunodeficiency Virus
Interventions: emtricitabine/tenofovir, CBT-based counseling; Drug · Behavioral
Lead sponsor: James Egan; Other
Eligibility: 18 Years and older · Male only
Enrollment: 54 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2017
U.S. locations: 2
States / cities: Boston, Massachusetts • Pittsburgh, Pennsylvania

Conditions: Leukemia
Interventions: Prophylactic White Cell Transfusion, Therapeutic White Cell Transfusion; Procedure
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 2 Years and older
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Contraceptive Behavior, Sexually Transmitted Diseases
Interventions: follow-up phone counseling; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 14 Years to 18 Years · Female only
Enrollment: 800 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2009
U.S. locations: 1
States / cities: San Francisco, California

Conditions: HIV/AIDS
Interventions: PrEP campaign messages developed via open contest, PrEP campaign messages developed via social marketing approach; Behavioral
Lead sponsor: Johns Hopkins Bloomberg School of Public Health; Other
Eligibility: 18 Years and older · Male only
Enrollment: 23 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Sex, Unprotected Sex, Contraception, Alcohol Use, Drug Use, Pregnancy
Interventions: Respecting the Circle of Life (RCL), Control Program; Behavioral · Other
Lead sponsor: Johns Hopkins Bloomberg School of Public Health; Other
Eligibility: 11 Years and older
Enrollment: 1,072 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2022
U.S. locations: 1
States / cities: Whiteriver, Arizona

Conditions: Hepatitis C Virus (HCV), Hepatitis C Virus (HCV) Infection, HIV (Human Immunodeficiency Virus)
Interventions: Physician-Initiated Screening (Conventional Screening), FOCUS (Universal Screening), HepC-EnD (Targeted Screening); Other
Lead sponsor: University of Florida; Other
Eligibility: 18 Years to 79 Years
Enrollment: 6,466 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 3
States / cities: Gainesville, Florida • Jacksonville, Florida

Conditions: Hyperandrogenism
Interventions: Blood sampling; Other
Lead sponsor: University of Virginia; Other
Eligibility: 8 Years to 15 Years · Female only
Enrollment: 90 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2023
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Unprotected Sex, Contraceptive Usage
Interventions: Pulse; Behavioral
Lead sponsor: Child Trends; Other
Eligibility: 18 Years to 20 Years · Female only
Enrollment: 2,317 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Fragile X Syndrome
Interventions: MG01CI extended-release tablet; Drug
Lead sponsor: Alcobra Ltd.; Industry
Eligibility: 15 Years to 55 Years
Enrollment: 62 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 11
States / cities: Phoenix, Arizona • Sacramento, California • Aurora, Colorado + 8 more

Conditions: IUD, Contraceptive Implant, Contraception, Birth Control, Emergency Contraception
Interventions: Copper T-380 IUD, LNG IUD, Contraceptive implant Nexplanon, Depo-Provera; Drug · Device
Lead sponsor: University of Utah; Other
Eligibility: 15 Years to 45 Years · Female only
Enrollment: 270 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2021
U.S. locations: 1
States / cities: West Valley City, Utah

Conditions: HIV
Interventions: Social Network Intervention, Counsel, Test, and Treat; Behavioral
Lead sponsor: Medical College of Wisconsin; Other
Eligibility: 18 Years and older · Male only
Enrollment: 856 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2017
U.S. locations: 2
States / cities: Cleveland, Ohio • Milwaukee, Wisconsin

Conditions: HIV Infections, Herpes Genitalis, HIV Seronegativity, Syphilis
Interventions: Not listed
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 18 Years and older · Male only
Enrollment: 250 participants
Healthy volunteers: Accepts healthy volunteers
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Sex Work
Interventions: Community based combination HIV prevention package; Behavioral
Lead sponsor: Johns Hopkins Bloomberg School of Public Health; Other
Eligibility: 18 Years and older · Female only
Enrollment: 385 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Emergency Contraception
Interventions: CDB-2914; Drug
Lead sponsor: HRA Pharma; Industry
Eligibility: 18 Years and older · Female only
Enrollment: 1,623 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 17
States / cities: San Jose, California • Denver, Colorado • Miami, Florida + 14 more

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A Couple-Based Relationship Strengthening HIV Intervention for Young Parents

Oral Islatravir (MK-8591) Once-Monthly as Preexposure Prophylaxis (PrEP) in Men and Transgender Women Who Are at High Risk for HIV-1 Infection (MK-8591-024)

SELF-CERV Pivotal Study: SELF-Collection for CERVical Cancer Screening

Moon and Sun Brothers: A Community Prevention Intervention (Hermanos de Luna y Sol)

Aripiprazole Treatment for Methamphetamine Dependence Among High-risk Individuals

HIV/STI Risk Reduction for Incarcerated Women With Interpersonal Violence

Artesunate Suppositories for the Treatment of HIV-negative Patients With Intra-anal HSIL

Defining the PrEP Care Continuum Among Recently Incarcerated Men at High-Risk for HIV Infection

Linking High-Risk Jail Detainees to HIV Pre-Exposure Prophylaxis: PrEP-LINK

Alcohol and "Heat of the Moment" Sexual Decision Making

Feasibility of Short-Term PrEP Uptake for MSM With Episodic High-Risk for HIV

Prophylactic White Cell Transfusions Versus Therapeutic White Cell Transfusions in Patients With Leukemia

The Young Woman's Reach Project: Trial of an Intervention to Impact Contraceptive Behavior, Unintended Pregnancy, and Sexually Transmitted Infections (STIs) Among Adolescent Females

Using Open Contest and Neuro-influence Experiment to Develop and Evaluate PrEP Promotion Messages for High Risk Men

Evaluation of Respecting the Circle of Life on Pregnancy Prevention Outcomes Among American Indian Adolescents

Assessing Performance of a Hepatitis C Emergency Department (HepC-EnD) Screening Tool: IT Integration Process for Electronic Health Record System

Sleep-wake Changes of Luteinizing Hormone Frequency in Pubertal Girls With and Without High Testosterone

The Evaluation of Pulse: A Mobile Health App and Teen Pregnancy Prevention Program

A 6-week, Study of MG01CI Low Dose and High Dose Compared With Placebo in Adults and Adolescents With Fragile X Syndrome

Quick Start of Highly Effective Contraception

Prevention of HIV Infection in High-Risk Social Networks of African American Men Who Have Sex With Men (MSM)

HIV and Genital Herpes Among High-Risk Men Who Have Sex With Men (MSM) in Lima, Peru

A Structural HIV Prevention Intervention Targeting High-risk Women

Safety and Efficacy of CDB-2914 for Emergency Contraception