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ClinicalTrials.gov public records Last synced Nov 15, 2026, 6:00 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 97–120 of 129 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: High-risk Sex Clear all

Conditions: HIV Seropositivity
Interventions: Telephone-Administered Motivational Interviewing Plus Behavioral Skills Training, Telephone-Administered Coping Effectiveness Training; Behavioral
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 50 Years and older
Enrollment: 343 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2021
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Reproductive Behavior, Sexual Behavior, Adolescent Behavior, Contraception
Interventions: Dr. Erica; Behavioral
Lead sponsor: Columbia University; Other
Eligibility: 14 Years to 19 Years · Female only
Enrollment: 146 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: New York, New York

Conditions: Sexually Transmitted Diseases, Unsafe Sex, Substance-Related Disorders
Interventions: PACT, TAU; Behavioral
Lead sponsor: Columbia University; Other
Eligibility: 18 Years and older
Enrollment: 480 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: New York, New York

Conditions: HIV/AIDS
Interventions: Seek and Test Phase, Treat and Retain Phase; Behavioral
Lead sponsor: New York University; Other
Eligibility: 18 Years to 60 Years
Enrollment: 500 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: New York, New York

Conditions: Unsafe Sex, Risk Reduction
Interventions: PROJECT POWER, Power Health; Behavioral
Lead sponsor: Nova Southeastern University; Other
Eligibility: 18 Years to 60 Years · Male only
Enrollment: 211 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Risky Sexual Behavior, Emotion Regulation, Adolescent Behavior
Interventions: iTRAC-HERO; Behavioral
Lead sponsor: Klein Buendel, Inc.; Industry
Eligibility: 12 Years to 14 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Golden, Colorado

Conditions: HIV Infections
Interventions: Couples HIV testing and counseling, Individual HIV testing and counseling; Behavioral
Lead sponsor: Hunter College of City University of New York; Other
Eligibility: 17 Years to 65 Years · Male only
Enrollment: 384 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 2
States / cities: Ann Arbor, Michigan • New York, New York

Conditions: Enhanced Assess, Acknowledge, and Act Sexual Assault Resistance Program With Alcohol and Cannabis Content
Interventions: Enhanced Assess, Acknowledge, and Act Sexual Assault Resistance Program, Assessment Only Control; Behavioral
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years to 24 Years · Female only
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Alcohol Use, Drug Use, Diagnostic Self Evaluation, Gonorrhea, Unprotected Sex, Chlamydia, Trichomonas
Interventions: Project EMPWR, Optimized Standard Care (OSC); Behavioral · Other
Lead sponsor: Johns Hopkins Bloomberg School of Public Health; Other
Eligibility: 18 Years to 49 Years
Enrollment: 350 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Fort Apache, Arizona

Conditions: Amphetamine-Related Disorders
Interventions: Naltrexone, Placebo; Drug
Lead sponsor: San Francisco Department of Public Health; Government
Eligibility: 18 Years to 65 Years · Male only
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Neurodevelopmental Disorders, Neurodevelopmental Disorders (NDD), Neurodevelopmental Disorders and Developmental Abnormalities, Developmental Delay (Disorder), Cerebral Palsy (CP), Cerebral Palsy Hemiparetic Cerebral Palsy Spasticity Gait Disorders, Neurologic Postural Balance Impairment, Cerebral Palsy Infantile, Cerebral Palsy Spastic Hemiplegic, Cerebral Palsy, Dyskinetic, Autism Spectrum Disorder, Autism Spectrum Disorder (ASD, Hypoxic Ischemic Encephalopathy, Hypoxic Ischemic Encephalopathy (HIE), Traumatic Brain Injury (TBI), Sensory Processing Disorder, Chromosomal Abnormalities, Genetic Disorders, Down Syndrome (Trisomy 21), Fragile X Syndrome (FXS), RETT Syndrome With Proven MECP2 Mutation, Williams Syndrome, 22q11.2 Deletion Syndrome, Sensorimotor Integration
Interventions: Not listed
Lead sponsor: Healing Hope International; Other
Eligibility: 4 Years to 12 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2036
U.S. locations: 1
States / cities: The Woodlands, Texas

Conditions: HIV Disease, Chronic Pain
Interventions: Communication Strategy, Standard of Care; Other
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years and older
Enrollment: 42 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: New York, New York

Conditions: Condomless Sex, Human Immunodeficiency Virus (HIV), Sexually Transmitted Infection (STI), Alcohol and Drug Use
Interventions: Face-to-Face Young Women's CoOp (YWC), mHealth Young Women's CoOp (YWC), HIV Counseling and Testing; Behavioral
Lead sponsor: RTI International; Other
Eligibility: 18 Years to 25 Years · Female only
Enrollment: 652 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2020
U.S. locations: 4
States / cities: Durham, North Carolina • Greensboro, North Carolina • High Point, North Carolina + 1 more

Conditions: Human Immunodeficiency Virus, Human Papillomavirus-Related Anal Squamous Cell Carcinoma, High-Grade Squamous Intraepithelial Lesions
Interventions: Biospecimen Collection, Questionnaires; Other
Lead sponsor: University of California, San Francisco; Other
Eligibility: 21 Years and older
Enrollment: 217 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Unsafe Sex
Interventions: MyLife MyStyle group-level intervention; Behavioral
Lead sponsor: Los Angeles County Department of Public Health; Government
Eligibility: 18 Years to 29 Years · Male only
Enrollment: 528 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Gonorrhea
Interventions: Listerine Antiseptic Mouthwash Product, Biotene Mouthwash; Drug
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years to 45 Years · Male only
Enrollment: 89 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Papillomavirus Infections
Interventions: 851B; Drug
Lead sponsor: Takeda; Industry
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 22
States / cities: Colton, California • San Diego, California • Colorado Springs, Colorado + 19 more

Conditions: Risk Reduction Behavior
Interventions: Cognitive-behavioral therapy; Behavioral
Lead sponsor: Fenway Community Health; Other
Eligibility: 18 Years and older · Male only
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: AIDS-Related Anal Carcinoma, Anal Margin Squamous Cell Carcinoma, Anal Non-Keratinizing Squamous Cell Carcinoma, Anal Squamous Cell Carcinoma, HIV Infection, Rectal Squamous Cell Carcinoma, Stage II Rectal Cancer AJCC v8, Stage IIB Anal Cancer AJCC v8, Stage III Anal Cancer AJCC v8, Stage III Rectal Cancer AJCC v8
Interventions: Anoscopy, Biospecimen Collection, Capecitabine, Colonoscopy, Computed Tomography, Digital Rectal Examination, Echocardiography Test, Fludeoxyglucose F-18, Fluorouracil, Intensity-Modulated Radiation Therapy, Lymph Node Biopsy, Magnetic Resonance Imaging, Mitomycin, Nivolumab, Positron Emission Tomography, Proctoscopy, Questionnaire Administration, Sigmoidoscopy; Procedure · Drug · Other + 2 more
Lead sponsor: National Cancer Institute (NCI); NIH
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2031
U.S. locations: 14
States / cities: San Francisco, California • Washington D.C., District of Columbia • Tampa, Florida + 7 more

Conditions: Economic Hardship, Condomless Sex, Utilization, Health Care
Interventions: Job announcements plus HIV prevention text messages, educational sessions, economic resources, and mentoring., Job announcements; Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 24 Years
Enrollment: 500 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2028
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Sexual Behavior, Alcohol Drinking, Condomless Sex
Interventions: Online program; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years to 24 Years · Female only
Enrollment: 300 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: HIV Infections
Interventions: Healthy Futures parent education; Behavioral
Lead sponsor: Education Development Center, Inc.; Industry
Eligibility: 11 Years and older
Enrollment: 1,200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2013
U.S. locations: 1
States / cities: Newton, Massachusetts

Conditions: Responsible Sex
Interventions: Real Essentials; Behavioral
Lead sponsor: University of Denver; Other
Eligibility: Not listed
Enrollment: 1,135 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Denver, Colorado

Conditions: Mycobacterium Avium-intracellulare Infection, HIV Infections
Interventions: Nelfinavir mesylate, Nevirapine, Azithromycin; Drug
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 18 Years and older
Enrollment: 85 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Ends 2001
U.S. locations: 26
States / cities: Birmingham, Alabama • Los Angeles, California • San Diego, California + 17 more

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Telephone Counseling to Enhance the Quality and Safety of Romantic and Sexual Relationships in People Living and Aging With HIV

Reducing Teen Pregnancy in the Emergency Department

Protect and Connect: Couple HIV Prevention for Drug Involved Male Offenders

Hybrid STTR Intervention for Heterosexuals: Anonymous Testing and Confidential Care Linkage

Project Power: An HIV Risk Reduction Intervention for Black Men Who Have Sex With Men and Women (BMSM/W)

An Interactive Education Program to Reduce High Risk Behavior in Adolescents Ph II (iTRAC HERO)

Evaluating the Efficacy of Annual CHTC Retesting Among Male Couples at High Risk of HIV Infection

Development of an Alcohol, Cannabis, and Sexual Assault Risk Reduction Program for High Risk College Women

Trial of an Adapted STD Screening and Risk Reduction Intervention

Extended-Release Naltrexone to Treat Methamphetamine Dependence in Men Who Have Sex With Men (MSM)

Intensive Multimodal Neurorehabilitation Targeting Neuroplasticity in Pediatric Neurodevelopmental and Chromosomal Disorders

Toward Safer Opioid Prescribing for Chronic Pain in High Risk Populations

NC Young Women's CoOp

Anal High-risk HPV, HSIL, and Microbiome Among Hispanic Peoples Living With HIV (PLWH)

MyLife MyStyle Evaluation Project

Antibacterial Mouthwash for Pharyngeal Gonorrhea Prevention

Efficacy of 851B Gel for Treating High-Risk Cervical Human Papillomavirus Infection in Women.

HIV Prevention in Very High Risk Men Who Have Sex With Men

Therapy Adapted for High Risk and Low Risk HIV-Associated Anal Cancer

Education and Employment Support for HIV Prevention in Young Adults (ENSPIRE)

Young Adult Education on Alcohol & Health

Reducing HIV Risks in African American Teens

Evaluation of High School-based Relationship Education

A Study to Learn More About MAC Disease and the Use of Anti-HIV Drugs in Patients With Advanced HIV Infection