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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Highly Stressed Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

Effect of Diet Composition on Weight Change and Metabolic Parameters

NCT01642849
View directory record Official record
Conditions
Obesity, Inflammation
Interventions
high protein diet, high carbohydrate diet
Dietary Supplement
Lead sponsor
University of Tennessee
Other
Eligibility
20 Years to 50 Years · Female only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 16, 2012 · Synced Sep 11, 2026, 7:10 PM EDT
Terminated Phase 1 Interventional

Effect of High-Dose Vitamin D3 in Smokers and Non-Smokers With and Without HIV

NCT03270709
View directory record Official record
Conditions
HIV/AIDS, Vitamin D Deficiency, Smoker Lung
Interventions
Vitamin D3 450,000 IU orally
Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
2
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 20, 2021 · Synced Sep 11, 2026, 7:10 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Physiological Responses to Heat Stress During High-risk Events

NCT06907225
View directory record Official record
Conditions
Thermoregulation
Interventions
None-placebo
Other
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
2
States / cities
Fort Novosel, Alabama • Fort Jackson, South Carolina
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Sep 11, 2026, 7:10 PM EDT
Completed Not applicable Interventional

The Impact of a School-Based, Trauma-Informed CBT Intervention for Young Women

NCT03376633
View directory record Official record
Conditions
Anxiety, Anxiety Disorders, Behavioral Symptoms, Depression, Mental Disorders, Stress Disorders, Post-Traumatic, Stress Disorders, Traumatic, Trauma and Stressor Related Disorders, Wounds and Injuries
Interventions
Working on Womanhood (WOW)
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
Female only
Enrollment
5,106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 23, 2022 · Synced Sep 11, 2026, 7:10 PM EDT
Completed Not applicable Interventional

Effects of Pistachios on Cardiovascular Responses to Stress in Type 2 Diabetes

NCT00956735
View directory record Official record
Conditions
Cardiovascular Disease, Type 2 Diabetes
Interventions
Pistachio
Other
Lead sponsor
Penn State University
Other
Eligibility
30 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 15, 2013 · Synced Sep 11, 2026, 7:10 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Three New Ideas to Protect Special Forces From the Stress of High Altitude

NCT02463357
View directory record Official record
Conditions
Mountain Sickness
Interventions
Quercetin, Nifedipine extended release, Methazolamide, Metformin, Placebo, Nitrite
Dietary Supplement · Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 30 Years · Male only
Enrollment
148 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Alma, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 29, 2021 · Synced Sep 11, 2026, 7:10 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Green Tea and Reduction of Breast Cancer Risk

NCT00917735
View directory record Official record
Conditions
Breast Cancer
Interventions
Green tea extract supplement, Placebo
Drug · Other
Lead sponsor
University of Minnesota
Other
Eligibility
50 Years to 70 Years · Female only
Enrollment
1,075 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
5
States / cities
Edina, Minnesota • Maple Grove, Minnesota • Minneapolis, Minnesota + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 21, 2016 · Synced Sep 11, 2026, 7:10 PM EDT
Recruiting Not applicable Interventional

Community-based Approach to Lowering Stress Through Mindfulness

NCT06987799
View directory record Official record
Conditions
Depression, Hypertension
Interventions
Mindfulness-Based Stress Reduction (MBSR; CALM-Chicago Study)
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Sep 11, 2026, 7:10 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Efficacy and Safety of a Proprietary Blend of Ashwagandha Root Extract (Aqueous) in Adult Men and Women With High Stress and Anxiety: A Randomized, Double-blind, Three-arm, Parallel, Placebo-controlled Study

NCT06714942
View directory record Official record
Conditions
Stress, Anxiety
Interventions
Proprietary Blend of Ashwagandha, KSM-66 Ashwagandha root extract, Placebo
Dietary Supplement
Lead sponsor
SF Research Institute, Inc.
Network
Eligibility
18 Years to 65 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Dec 3, 2024 · Synced Sep 11, 2026, 7:10 PM EDT
Not listed Not applicable Interventional

Stress Management for High Blood Pressure

NCT02371317
View directory record Official record
Conditions
Prehypertension
Interventions
Mindfulness-Based Stress Reduction, Stress Management Education, American Heart Association Recommended Self-Care
Behavioral · Other
Lead sponsor
Kent State University
Other
Eligibility
21 Years to 70 Years
Enrollment
141 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
2
States / cities
Cleveland, Ohio • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 12, 2019 · Synced Sep 11, 2026, 7:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Tailored Health Self-Management Interventions for Highly Distressed Caregivers: Family Members of Persons With Dementia

NCT04247347
View directory record Official record
Conditions
Stress, Carer Stress Syndrome, Dementia, Alzheimer Disease
Interventions
Biofeedback Training, Dementia Education, Resourcefulness Training
Behavioral · Other
Lead sponsor
Case Western Reserve University
Other
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 11, 2026, 7:10 PM EDT
Completed No phase listed Observational

Withings Pulse Wave Velocity and Blood Pressure Study

NCT03099954
View directory record Official record
Conditions
Elevated Blood Pressure, Hypertension, Mental Stress, Sleep Disorders
Interventions
Not listed
Lead sponsor
Scripps Translational Science Institute
Other
Eligibility
18 Years and older
Enrollment
300 participants
Timeline
2017
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Feb 28, 2018 · Synced Sep 11, 2026, 7:10 PM EDT
Completed Phase 1Phase 2 Interventional

R(+)PPX High Dose Treatment of ALS

NCT00600873
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis
Interventions
R(+) pramipexole dihydrochloride monohydrate
Drug
Lead sponsor
Bennett, James P., Jr., M.D., Ph.D.
Individual
Eligibility
30 Years to 80 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 12, 2010 · Synced Sep 11, 2026, 7:10 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Estimating Blood [Lactate] Non-Invasively

NCT05036122
View directory record Official record
Conditions
Healthy
Interventions
LabClasp
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Sep 11, 2026, 7:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Heart Inflammation and Mental Stress Study

NCT03695146
View directory record Official record
Conditions
Hypertension
Interventions
Paced breathing, Active relaxation
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
21 Years to 65 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Feb 14, 2024 · Synced Sep 11, 2026, 7:10 PM EDT
Completed Phase 2 Interventional Results available

Measures to Lower the Stress Response in Pediatric Cardiac Surgery

NCT00848393
View directory record Official record
Conditions
Tetralogy of Fallot (TOF), Ventricular Septal Defects (VSD), Atrioventricular Septal Defects (AVSD)
Interventions
Fentanyl (High Dose), Fentanyl (Low Dose), Fentanyl (Low Dose) + Dexmedetomidine
Drug
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
1 Month to 3 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 26, 2018 · Synced Sep 11, 2026, 7:10 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Heat Therapy and Muscle Function Study

NCT04733287
View directory record Official record
Conditions
Exercise Intolerance, Aging, Heat Therapy, High Intensity Interval Training
Interventions
High Intensity Interval Training of the Knee Extensors, Muscle Heat Therapy, Muscle Disuse, Sham Heat Therapy
Other
Lead sponsor
Brigham Young University
Other
Eligibility
18 Years to 95 Years
Enrollment
148 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Provo, Utah
Source: ClinicalTrials.gov public record
Updated Feb 1, 2021 · Synced Sep 11, 2026, 7:10 PM EDT
Recruiting Not applicable Interventional

Development of a College Student-Delivered Cognitive-Behavioral Therapy (CBT) Intervention for Rural High School Students

NCT07240792
View directory record Official record
Conditions
Depression, Anxiety, Stress
Interventions
Student Delivered Cognitive Behavioral Therapy Intervention
Behavioral
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
13 Years to 18 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Sep 11, 2026, 7:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Arena Labs - Improving Clinician Well Being

NCT05653700
View directory record Official record
Conditions
Mental Health Disorder
Interventions
Arena Strive, Control Cohort
Device · Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 3, 2024 · Synced Sep 11, 2026, 7:10 PM EDT
Completed Not applicable Interventional Results available

HIRREM Developmental Study

NCT02709369
View directory record Official record
Conditions
Sleep Initiation and Maintenance Disorders, Anxiety, Post-Traumatic Stress Disorder, Hot Flashes, Headache, Traumatic Brain Injury, Post Concussion Symptoms
Interventions
HIRREM
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
11 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2018
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 23, 2019 · Synced Sep 11, 2026, 7:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Acute Effect of Spices on Vascular Health

NCT03064958
View directory record Official record
Conditions
Oxidative Stress
Interventions
Herbs and spices, High fat meal
Other
Lead sponsor
Penn State University
Other
Eligibility
40 Years to 65 Years · Male only
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 20, 2023 · Synced Sep 11, 2026, 7:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Brief App-based Mobile Health and Well-being Intervention Among Middle-aged Adults

NCT04272138
View directory record Official record
Conditions
Meditation, Control Group
Interventions
Calm Meditation, Educational Podcast Control
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
40 Years to 64 Years
Enrollment
83 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Feb 27, 2022 · Synced Sep 11, 2026, 7:10 PM EDT
Completed Not applicable Interventional

Feasibility Trial of a Lifestyle Intervention for CHR-P

NCT05532683
View directory record Official record
Conditions
Prodromal Schizophrenia, Psychosis, Psychological Disorder, Psychological Stress
Interventions
Health Behaviors Group
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
13 Years to 17 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 24, 2024 · Synced Sep 11, 2026, 7:10 PM EDT
Active, not recruiting Phase 2 Interventional

Nicotinamide Riboside Supplementation for Treating Arterial Stiffness and Elevated Systolic Blood Pressure in Patients With Moderate to Severe CKD

NCT04040959
View directory record Official record
Conditions
Vascular Diseases, Kidney Disease, Blood Pressure, Oxidative Stress
Interventions
Nicotinamide riboside
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
35 Years to 80 Years
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Sep 11, 2026, 7:10 PM EDT