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Showing 1–24 of 44 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Not yet recruiting Not applicable Interventional

Antibiotic-coated Braided Suture Study

NCT07322289
Conditions
Prosthetic Joint Infection, Debridement With Prosthesis Retention, Prosthetic Joint Infections of Hip, Prosthetic Joint Infections of Knee, Suture
Interventions
VICRYL™ Plus (Coated VICRYL™ Plus Antibacterial), Polydioxanone (PDS™ II ) Sterile Synthetic Absorbable Surgical Suture-Monofilament
Device
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 89 Years
Enrollment
142 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Miami, Florida
Conditions
Arthritis, Osteoarthritis, Knee, Osteoarthritis, Hip, Thromboembolism
Interventions
Rivaroxaban
Drug
Lead sponsor
Ortho-McNeil Janssen Scientific Affairs, LLC
Industry
Eligibility
18 Years to 99 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
5
States / cities
Denver, Colorado • Hollywood, Florida • Tamarac, Florida + 2 more
Conditions
Prosthetic Joint Infection
Interventions
Bacteriophage, Placebo
Drug
Lead sponsor
Adaptive Phage Therapeutics, Inc.
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
10
States / cities
San Diego, California • Hartford, Connecticut • Idaho Falls, Idaho + 5 more
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Relationship Between Anesthetic Regimen and Bone Cement Implantation Syndrome (BCIS)

NCT06952257
Conditions
Bone Cement Implantation Syndrome
Interventions
Administration of general anaesthesia, Neuraxial Analgesia
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Hip Replacement
Interventions
REDAPT
Device
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years and older
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2034
U.S. locations
4
States / cities
Rancho Mirage, California • San Diego, California • New York, New York
Conditions
Non-inflammatory Degenerative Joint Disease, Osteoarthritis, Avascular Necrosis, Post-traumatic Arthritis
Interventions
Ceramax Acetabular System
Device
Lead sponsor
DePuy Orthopaedics
Industry
Eligibility
Not listed
Enrollment
185 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
12
States / cities
Sacramento, California • Denver, Colorado • Fort Collins, Colorado + 8 more
Conditions
Aseptic Loosening, Osteolysis, Traumatic Fracture, Failed Total Hip Implant
Interventions
Modular Revision Hip System
Device
Lead sponsor
Encore Medical, L.P.
Industry
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
6
States / cities
Burbank, California • Redwood City, California • Syracuse, New York + 3 more
Conditions
Periprosthetic Joint Infection
Interventions
Single Debridement, Antibiotics and Implant Retention, Planned Double Debridement, Antibiotics and Implant Retention
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
490 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2032
U.S. locations
2
States / cities
Jacksonville, Florida • Rochester, Minnesota
Conditions
Non-inflammatory Degenerative Joint Disease
Interventions
Total Hip Replacement
Procedure
Lead sponsor
Anderson Orthopaedic Research Institute
Other
Eligibility
40 Years to 80 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2013
U.S. locations
1
States / cities
Alexandria, Virginia
Conditions
Hip Arthritis, Hip Disease, Hip Fractures, Hip Injuries, Hip Pain Chronic
Interventions
RingLoc Bipolar Acetabular Cup, Endo II Femoral Head
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Falls Church, Virginia
Withdrawn No phase listed Observational Accepts healthy volunteers

MRI Scanning of People With MR Safe Orthopedic Implants That Are Made of Metal

NCT01570543
Conditions
Implants
Interventions
Not listed
Lead sponsor
GE Healthcare
Industry
Eligibility
18 Years to 85 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Waukesha, Wisconsin
Conditions
Arthroplasties, Hip Replacement
Interventions
REDAPT Revision Femoral System modular stem
Device
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
Not listed
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
3
States / cities
Louisville, Kentucky • Detroit, Michigan • Portland, Oregon
Conditions
Hip Injuries, Tendon Injuries, Orthopedic Procedures
Interventions
Standard gluteus medius repair with Tapestry Biointegrative implant
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
3
States / cities
Columbus, Ohio • Westerville, Ohio
Conditions
Advanced Degeneration of the Hip Joint, Revision of the Hip Joint
Interventions
Primary Total Hip Arthroplasty, Revision Total Hip Arthroplasty
Device
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
177 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2035
U.S. locations
6
States / cities
Lexington, Kentucky • Omaha, Nebraska • New York, New York + 2 more
Conditions
Shoulder Injuries, Knee Injuries, Hip Injuries
Interventions
Standard of Care Treatment
Device
Lead sponsor
Stryker Endoscopy
Industry
Eligibility
18 Years and older
Enrollment
1,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
3
States / cities
Phoenix, Arizona • Englewood, Colorado • San Antonio, Texas
Not yet recruiting No phase listed Observational

Mako-MORE Registry

NCT07647354
Conditions
Arthropathy of Knee, Arthropathy of Hip
Interventions
Mako Robotic-Arm Assisted Arthroplasty
Device
Lead sponsor
Stryker Orthopaedics
Industry
Eligibility
18 Years and older
Enrollment
950 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2037
U.S. locations
5
States / cities
Jacksonville, Florida • Louisville, Kentucky • New York, New York + 2 more
Completed Not applicable Interventional Results available

Metal on Metal Versus Ceramic on Metal Hip Replacement

NCT00208494
Conditions
Non-inflammatory Joint Diseases
Interventions
Total hip replacement
Device
Lead sponsor
DePuy Orthopaedics
Industry
Eligibility
20 Years to 75 Years
Enrollment
392 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2011
U.S. locations
8
States / cities
Little Rock, Arkansas • Orange, California • Palm Bay, Florida + 5 more
Conditions
Cartilage Defect
Interventions
Autologous Chondrocytes in their Pericellular Matrix (Chondrons) Coimplanted with Allogeneic Adipose-Derived Mesenchymal Stromal Cells (AMSCs) in a Fibrin Glue Carrier
Combination Product
Lead sponsor
Daniel B. F. Saris
Other
Eligibility
18 Years to 50 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Osteoarthritis, Rheumatoid Arthritis, Post-traumatic Arthritis, Avascular Necrosis, Acute Fracture
Interventions
non-coated femoral hip stem, coated femoral hip stem
Device
Lead sponsor
DePuy Orthopaedics
Industry
Eligibility
Up to 75 Years
Enrollment
245 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2009
U.S. locations
1
States / cities
Warsaw, Indiana
Conditions
Femoral Neck Fractures
Interventions
Sliding Hip Screw, Cancellous Screws, Vitamin D, Vitamin D Placebo
Procedure · Drug
Lead sponsor
McMaster University
Other
Eligibility
18 Years to 60 Years
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
10
States / cities
Phoenix, Arizona • San Francisco, California • Gainesville, Florida + 7 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Two Year Study With Robotic-Arm Assisted Hip Surgery.

NCT03891199
Conditions
Surgery, Hip Osteoarthritis
Interventions
Robotic-Arm Assisted THA
Procedure
Lead sponsor
West Virginia University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Morgantown, West Virginia
Conditions
Implant Position in Total Hip Replacement
Interventions
Not listed
Lead sponsor
Barrett, William, M.D.
Individual
Eligibility
20 Years to 75 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Renton, Washington
Conditions
Femoro Acetabular Impingement
Interventions
LoopLoc Arm, Control Arm
Device
Lead sponsor
American Hip Institute
Other
Eligibility
18 Years to 60 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Des Plaines, Illinois
Conditions
Non-inflammatory Degenerative Joint Disease, Osteoarthritis, Avascular Necrosis, Post-Traumatic Osteoarthritis of Hip
Interventions
COC 36mm
Device
Lead sponsor
DePuy Orthopaedics
Industry
Eligibility
21 Years to 75 Years
Enrollment
172 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2023
U.S. locations
9
States / cities
Sacramento, California • Denver, Colorado • Tampa, Florida + 5 more