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ClinicalTrials.gov public records Last synced Sep 5, 2026, 7:16 AM EDT

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Showing 1–24 of 85 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Hoarseness Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

Brain Network Changes After Vibro-tactile Stimulation in Laryngeal Dystonia

NCT07443891
View directory record Official record
Conditions
Laryngeal Dystonia
Interventions
Vibrotactile Stimulation (VTS)
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced Sep 5, 2026, 7:16 AM EDT
Withdrawn No phase listed Observational

Examining the Spasmodic Dysphonia Diagnosis and Assessment Procedure (SD-DAP) for Measuring Symptom Change

NCT02061943
View directory record Official record
Conditions
Spasmodic Dysphonia, Laryngeal Dystonia
Interventions
Not listed
Lead sponsor
Emory University
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
2
States / cities
Atlanta, Georgia • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 29, 2016 · Synced Sep 5, 2026, 7:16 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Brain-Computer Interfaces in Laryngeal Dystonia

NCT04421365
View directory record Official record
Conditions
Laryngeal Dystonia
Interventions
neurofeedback brain-computer interface (BCI)
Device
Lead sponsor
Kristina Simonyan
Other
Eligibility
18 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 1, 2025 · Synced Sep 5, 2026, 7:16 AM EDT
Recruiting No phase listed Observational

Deep Brain Stimulation for Laryngeal Dystonia: From Mechanism to Optimal Application

NCT05506085
View directory record Official record
Conditions
Laryngeal Dystonia, Adductor Spastic Dysphonia of Dystonia
Interventions
Deep Brain Stimulation
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 70 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2030
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Sep 5, 2026, 7:16 AM EDT
Completed No phase listed Observational

LMA Cuff Pressure and LMA-induced Complications

NCT01385969
View directory record Official record
Conditions
Sore Throat, Dysphagia, Dysphonia
Interventions
Standard inflation of LMA cuff, Pressure check with syringe recoil, Pressure check by pressure transducer
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 99 Years
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
2
States / cities
Gainesville, Florida • Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 5, 2015 · Synced Sep 5, 2026, 7:16 AM EDT
Completed No phase listed Observational

Efficacy of Conversation Training Therapy (CTT)

NCT02441348
View directory record Official record
Conditions
Voice Disorders
Interventions
Conversation Training Therapy
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 60 Years
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 7, 2019 · Synced Sep 5, 2026, 7:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Post-operative Sore Throat as Determined by Endotracheal Tube Inflation Technique

NCT01305265
View directory record Official record
Conditions
Post Operative Sore Throat, Dysphagia, Hoarseness
Interventions
cuff manometer
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
141 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Feb 25, 2014 · Synced Sep 5, 2026, 7:16 AM EDT
Withdrawn Phase 2 Interventional

Laryngeal Vibro-tactile Stimulation as a Non-invasive Symptomatic Treatment for Spasmodic Dysphonia

NCT05467228
View directory record Official record
Conditions
Adductor Spasmodic Dysphonia, Abductor Spastic Dysphonia, Laryngeal Dystonia
Interventions
vibro-tactile stimulation (VTS)
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated May 15, 2025 · Synced Sep 5, 2026, 7:16 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Usefulness and Feasibility of Ultrasound in Office Laryngology Procedures

NCT06579989
View directory record Official record
Conditions
Cough, Vocal Cord Atrophy, Vocal Cord Paresis, Vocal Cord Paralysis, Dysphagia, Dysphonia
Interventions
Ultrasound for cough, Ultrasound for vocal fold atrophy or vocal fold paresis/paralysis, Ultrasound for dysphagia, Ultrasound for dysphonia
Diagnostic Test
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 99 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2030
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Sep 5, 2026, 7:16 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Central Mechanisms in Speech Motor Control Studied With H215O PET

NCT00001308
View directory record Official record
Conditions
Communication Disorder, Healthy, Stuttering, Tourette Syndrome, Voice Disorder
Interventions
Not listed
Lead sponsor
National Institute on Deafness and Other Communication Disorders (NIDCD)
NIH
Eligibility
18 Years to 85 Years
Enrollment
1,163 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1992 – 2016
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 16, 2019 · Synced Sep 5, 2026, 7:16 AM EDT
Completed No phase listed Observational

Sensory Function in Idiopathic Voice Disorders

NCT00001922
View directory record Official record
Conditions
Phonation Disorder, Spastic Dysphonia, Voice Disorder
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
20 Years to 80 Years
Enrollment
370 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 1998
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Sep 5, 2026, 7:16 AM EDT
Completed No phase listed Observational

Role of Neurotransmission and Functional CNS Networks in Spasmodic Dysphonia

NCT00713414
View directory record Official record
Conditions
Spasmodic Dysphonia, Focal Dystonia
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
21 Years to 80 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 4, 2018 · Synced Sep 5, 2026, 7:16 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Use of Osteopathic Medical Manipulation to Decrease the Incidence and Severity of Post-Operative Sore Throat

NCT03720301
View directory record Official record
Conditions
Pharyngitis, Dysphonia
Interventions
Osteopathic Manipulation Treatment, Sham
Procedure
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years and older
Enrollment
168 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Oct 24, 2018 · Synced Sep 5, 2026, 7:16 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Improving Voice Production for Adults With Age-related Dysphonia

NCT03702322
View directory record Official record
Conditions
Presbylarynx, Age-Related Dysphonia
Interventions
Voice therapy: respiratory, Voice therapy: glottal closure, Voice therapy: loud, Voice therapy: Semiocclusion
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
65 Years and older
Enrollment
220 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
2
States / cities
Scottsdale, Arizona • Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Oct 9, 2025 · Synced Sep 5, 2026, 7:16 AM EDT
Completed Phase 2 Interventional

Firdapse for Post-BOTOX Vocal Weakness

NCT05123053
View directory record Official record
Conditions
Vocal Weakness(Post-BOTOX Injection)
Interventions
Amifampridine
Drug
Lead sponsor
Augusta University
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 2, 2025 · Synced Sep 5, 2026, 7:16 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Study of Air Stream in Voice Production

NCT00015795
View directory record Official record
Conditions
Spastic Dysphonia, Healthy
Interventions
airway interruption test
Device
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2003
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Sep 5, 2026, 7:16 AM EDT
Not yet recruiting Not applicable Interventional

Assessment of Laryngopharyngeal Sensation: Cancer Survivor Cohort

NCT06078527
View directory record Official record
Conditions
Presbylarynx, Aspiration, Spasmodic Dysphonia, Globus Pharyngeus, Larynx Paralysis, Laryngeal Disease, Vocal Cord Paralysis, Iatrogenic Injury, Sensory Neuropathy
Interventions
Cheung-Bearelly Aesthesiometer, Transnasal Laryngoscopy, Questionnaires
Device · Procedure · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 22, 2025 · Synced Sep 5, 2026, 7:16 AM EDT
Not yet recruiting Phase 1 Interventional

Extended-release Sodium Oxybate (Lumryz) in Spasmodic Dysphonia and Voice Tremor

NCT07041203
View directory record Official record
Conditions
Spasmodic Dysphonia, Laryngeal Dystonia, Voice Tremor
Interventions
sodium oxybate
Drug
Lead sponsor
Kristina Simonyan
Other
Eligibility
21 Years to 80 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Sep 5, 2026, 7:16 AM EDT
Completed Phase 1Phase 2 Interventional Results available

DaxibotulinumtoxinA Injection for Treatment of Adductor Spasmodic Dysphonia

NCT05158166
View directory record Official record
Conditions
Adductor Spasmodic Dysphonia, Voice Disorders, Spasmodic Dysphonia
Interventions
DaxibotulinumtoxinA
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced Sep 5, 2026, 7:16 AM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Understanding Disorder-specific Neural Pathophysiology in Laryngeal Dystonia and Voice Tremor

NCT05216770
View directory record Official record
Conditions
Laryngeal Dystonia, Spasmodic Dysphonia, Tremor
Interventions
Brain imaging, Laryngeal sensory block with topical bupivacaine
Other · Drug
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
18 Years to 80 Years
Enrollment
165 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 1, 2025 · Synced Sep 5, 2026, 7:16 AM EDT
Completed Phase 1 Interventional

Dextromethorphan to Treat Patients With Voice Spasms

NCT00055549
View directory record Official record
Conditions
Voice Disorders
Interventions
Dextromethorphan, Lorazepam
Drug
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 80 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2009
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Sep 5, 2026, 7:16 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

A Study to Analyze Symptoms Prevalent in Early PD (Dysphonia, Tremor)

NCT04288804
View directory record Official record
Conditions
Parkinson Disease
Interventions
Smartphone microphone sensor, Smartphone accelerometer sensor
Device
Lead sponsor
Goalspal LLC
Other
Eligibility
Not listed
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Pleasanton, California
Source: ClinicalTrials.gov public record
Updated Aug 2, 2022 · Synced Sep 5, 2026, 7:16 AM EDT
Withdrawn Not applicable Interventional

The Effects of Adding Expiratory Muscle Strength Training in Voice Therapy

NCT03692494
View directory record Official record
Conditions
Dysphonia, Unilateral Vocal Cord Paralysis
Interventions
Standard of care voice therapy, Expiratory muscle strength training (EMST)
Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Feb 6, 2025 · Synced Sep 5, 2026, 7:16 AM EDT
Terminated Not applicable Interventional Results available

Retrospective TIF Study for Treatment of Gastroesophageal Reflux Disease (GERD). The RetroTIF Study

NCT01327963
View directory record Official record
Conditions
Gastroesophageal Reflux Disease (GERD)
Interventions
Transoral Incisionless Fundoplication
Device
Lead sponsor
EndoGastric Solutions
Industry
Eligibility
18 Years to 85 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
2
States / cities
Ocala, Florida • Salem, Kentucky
Source: ClinicalTrials.gov public record
Updated Dec 2, 2020 · Synced Sep 5, 2026, 7:16 AM EDT