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Showing 1–24 of 138 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Homeless Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Contingency Management for Smoking Cessation in Homeless Smokers

NCT01789710
View directory record Official record
Conditions
Smoking, Homeless Persons
Interventions
Bupropion, Nicotine replacement therapy, Contingency Management
Drug · Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 70 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 3, 2026 · Synced Sep 2, 2026, 5:40 PM EDT
Completed Not applicable Interventional Results available

Examining the Feasibility and Acceptability of a Tailored Version of a Mindfulness-Based Intervention (MBI) Among Youth Experiencing Homelessness (YEH)

NCT04950816
View directory record Official record
Conditions
Stress, Emotional
Interventions
tailored MBI (.b), attention control condition
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 25 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 27, 2025 · Synced Sep 2, 2026, 5:40 PM EDT
Completed Not applicable Interventional Results available

Behavior Change Intervention for Cardiovascular Risk Reduction Among People Experiencing Homelessness

NCT06025721
View directory record Official record
Conditions
Heart Diseases, Diabetes Mellitus, Type 2, Pre-diabetes, Hypertension, Hyperlipidemias
Interventions
Cardiovascular Risk Homeless Support
Behavioral
Lead sponsor
Katherine Vickery
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 7, 2025 · Synced Sep 2, 2026, 5:40 PM EDT
Recruiting Not applicable Interventional

Hepatitis C Tracker Study

NCT06870019
View directory record Official record
Conditions
Hepatitis C Virus Infection
Interventions
GPS tracker device
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Alhambra, California • Ventura, California
Source: ClinicalTrials.gov public record
Updated Aug 28, 2025 · Synced Sep 2, 2026, 5:40 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Improving Productive Community Integration in Homeless-experienced Veterans

NCT07388641
View directory record Official record
Conditions
Homeless Persons
Interventions
Motivational Interviewing and Cognitive Behavioral Therapy, Healthy Behavior Training
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
106 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2031
U.S. locations
1
States / cities
West Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Sep 2, 2026, 5:40 PM EDT
Recruiting No phase listed Observational

Shelter HArm Reduction Evaluation

NCT07170072
View directory record Official record
Conditions
Overdose, Harm Reduction
Interventions
Not listed
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Sep 2, 2026, 5:40 PM EDT
Completed Not applicable Interventional Results available

A Pilot Randomized Controlled Trial of Financial Incentives, Text Messaging, and Usual Care for Homeless Smokers

NCT02565381
View directory record Official record
Conditions
Smoking
Interventions
Transdermal nicotine patch, In-person smoking cessation counseling, Contingent financial rewards for smoking abstinence, Text messages to support smoking abstinence
Drug · Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 13, 2017 · Synced Sep 2, 2026, 5:40 PM EDT
Completed Not applicable Interventional

Educational Module and Decision Counseling Program in Increasing Mammography Screening Rates in Formerly Homeless Women With Serious Mental Illness

NCT03162887
View directory record Official record
Conditions
Breast - Female
Interventions
Educational Intervention, Counseling, Informational Intervention
Other
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Other
Eligibility
40 Years and older · Female only
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 21, 2025 · Synced Sep 2, 2026, 5:40 PM EDT
Completed Not applicable Interventional Results available

Diabetes Homelessness Medication Support Program in Spanish

NCT05819749
View directory record Official record
Conditions
Diabetes Mellitus, Type 2
Interventions
Diabetes Homelessness Medication Support Program in Spanish
Behavioral
Lead sponsor
Hennepin Healthcare Research Institute
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 8, 2024 · Synced Sep 2, 2026, 5:40 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of EBT With Young, Substance Abusing Homeless Mothers

NCT02577666
View directory record Official record
Conditions
Substance Use
Interventions
Ecologically Based Therapy, Housing Only, Treatment as Usual
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 24 Years · Female only
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 23, 2019 · Synced Sep 2, 2026, 5:40 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Advance Care Planning With Formerly Homeless Older Adults Residing in Permanent Supportive Housing

NCT06239896
View directory record Official record
Conditions
Advance Care Planning
Interventions
Facilitated Group ACP Session, Facilitated one-on-one ACP visits
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
50 Years and older
Enrollment
650 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
6
States / cities
Fremont, California • Oakland, California • San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 19, 2025 · Synced Sep 2, 2026, 5:40 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Evaluating the Impact of Emergency Maternity Housing

NCT05428514
View directory record Official record
Conditions
Housing Problems, Pregnancy Related
Interventions
Maternity Housing
Other
Lead sponsor
University of Notre Dame
Other
Eligibility
18 Years and older · Female only
Enrollment
1,048 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Notre Dame, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 22, 2022 · Synced Sep 2, 2026, 5:40 PM EDT
Completed Not applicable Interventional

MISSION-CJ for Justice-Involved Homeless Veterans

NCT04523337
View directory record Official record
Conditions
Substance Use Disorder, Mental Health Disorder, Homelessness
Interventions
Maintaining Maintaining Independence and Sobriety through Systems Integration Outreach and Networking- Criminal Justice, Maintaining Maintaining Independence and Sobriety through Systems Integration Outreach and Networking Peer Support
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
3
States / cities
Little Rock, Arkansas • Palo Alto, California • Bedford, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 16, 2026 · Synced Sep 2, 2026, 5:40 PM EDT
Recruiting Not applicable Interventional

Building Social and Structural Connections for the Prevention of Opioid Use Disorder Among Youth Experiencing Homelessness

NCT06311838
View directory record Official record
Conditions
Opioid Use Disorder, Dual Diagnosis, Housing Problems, Mental Disorder in Adolescence, Risk Behavior, Homelessness
Interventions
Motivational Interviewing/Community Reinforcement Approach (MI/CRA), Strengths-Based Outreach and Advocacy (SBOA ), Services as Usual (SAU)
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
14 Years to 24 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
2
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 21, 2025 · Synced Sep 2, 2026, 5:40 PM EDT
Completed Not applicable Interventional Results available

Diabetes Homeless Medication Support Single Arm Treatment Development Trial

NCT04678284
View directory record Official record
Conditions
Type 2 Diabetes, Homeless Persons
Interventions
Diabetes Homeless Medication Support (D-Homes)
Behavioral
Lead sponsor
Hennepin Healthcare Research Institute
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 17, 2023 · Synced Sep 2, 2026, 5:40 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Intervention to Improve Expression of End of Life Preferences for Homeless Persons

NCT00546884
View directory record Official record
Conditions
Healthy
Interventions
MI condition, GI
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
262 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
2
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 12, 2017 · Synced Sep 2, 2026, 5:40 PM EDT
Completed Not applicable Interventional Results available

Lung Cancer Screening Navigation for Homeless People

NCT04308226
View directory record Official record
Conditions
Lung Cancer, Tobacco Use, Homelessness
Interventions
Patient Navigation
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
55 Years to 77 Years
Enrollment
261 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 8, 2024 · Synced Sep 2, 2026, 5:40 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparative Effectiveness of Stress Management

NCT03203902
View directory record Official record
Conditions
Stress
Interventions
Psychoeducation and Therapeutic Touch
Other
Lead sponsor
Columbia University
Other
Eligibility
21 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 24, 2018 · Synced Sep 2, 2026, 5:40 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

QAIAx (AIhealth4U) - AI Public Health Central: Microcity-A (re Quantum AI Agency Aka AI City Hall Project, UPSTO App Nos. 64/074,526, 64/063,557, 63/903,181, 63/729,428

NCT07661823
View directory record Official record
Conditions
Asperger's Disorder, Asperger Disorder, Autism Disorder, Autism, ADHD - Attention Deficit Disorder With Hyperactivity, ADHD, ASD, Alcohol Abuse/Dependence, Alcohol Addiction, Alcohol and Other Drug Use Disorders, Alcohol and Other Substance Use Prevention, Gambling Addiction, Gambling Disorder, Sex Abuse, Sex Behavior, Sex Crimes, Sex Disorder, Sex Disorders, Gender Dysphoria, Adult, Eating Behavior Disorders, Narcotic-Related Disorders, Narcotic Addiction, Narcissism, Psychiatric Disorder, Psychedelic Effects in Healthy Volunteers, Psychedelic Experiences, Psychedelic Drug Dependence, Marijuana Use Disorder, Marijuana Abuse and Dependence, Smoking (Tobacco) Addiction, Smoking Among Youth, Smoking Abstinence, Abstinence, Sex, Opiate Substitution Treatment, Opioid Abuse (Disorder), Opioid Abuse and Addiction, Cocaine Abuse, MDMA ('Ecstasy'), Addiction Disorders, Homeless and Low Incomes People, Refugees, Homelessness, Reliability and Validity, Anger Problems, Child Abuse, Sexual
Interventions
AI City Hall Project (AIhealth4u - Public Health Central), AI City Hall Project (QAIAx Microcity A - AI Public Health Central)
Behavioral
Lead sponsor
Veterans Recovery Network Inc.
Other
Eligibility
17 Years to 99 Years
Enrollment
1,000,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Sep 2, 2026, 5:40 PM EDT
Withdrawn Not applicable Interventional

Rebuilding Bridges for Homeless Veterans

NCT03329157
View directory record Official record
Conditions
Housing Problems
Interventions
Rebuilding Bridges
Other
Lead sponsor
VA Connecticut Healthcare System
Federal
Eligibility
Not listed
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 21, 2025 · Synced Sep 2, 2026, 5:40 PM EDT
Completed Not applicable Interventional

Contingency Management for Smoking Cessation in the Homeless

NCT01736982
View directory record Official record
Conditions
Cigarette Smoking
Interventions
Contingency Management, Standard of Care
Behavioral · Other
Lead sponsor
UConn Health
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
New Britain, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 15, 2018 · Synced Sep 2, 2026, 5:40 PM EDT
Completed Not applicable Interventional

Utilizing Battlefield Acupuncture(BFA) to Treat Chronic Pain for Homeless and at Risk Veterans.

NCT05417724
View directory record Official record
Conditions
Acupuncture, Homelessness, Pain, Veterans
Interventions
Battlefield Acupuncture
Other
Lead sponsor
Edith Nourse Rogers Memorial Veterans Hospital
Federal
Eligibility
18 Years to 100 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Bedford, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 11, 2023 · Synced Sep 2, 2026, 5:40 PM EDT
Completed Not applicable Interventional

Self-Management Using Text Messaging in a Homeless Population

NCT03034993
View directory record Official record
Conditions
Chronic Disease
Interventions
Text Messaging
Behavioral
Lead sponsor
Boston University
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 2, 2019 · Synced Sep 2, 2026, 5:40 PM EDT
Enrolling by invitation Not applicable Interventional

Silicon Valley Guaranteed Income Project

NCT05698498
View directory record Official record
Conditions
Families Experiencing Homelessness and/or Housing Instability, Housing Stability
Interventions
Guaranteed Income, Public Benefits Information Session
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
2
States / cities
San Jose, California
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Sep 2, 2026, 5:40 PM EDT