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Showing 1–24 of 56 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Hormonal Contraception Clear all
Recruiting Phase 2 Interventional Accepts healthy volunteers

Phase II Study of Ovulation in Obese Women

NCT06306131
View directory record Official record
Conditions
Pregnancy Prevention
Interventions
Levonorgestrel 0.15 milligram, Meloxicam 15 milligram, calcium carbonate 750 milligram
Drug · Other
Lead sponsor
InnovaGyn, Inc.
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 21, 2025 · Synced Jun 25, 2026, 10:45 PM EDT
Not yet recruiting Not applicable Interventional

Energy Deficiency on Hormones in Contraceptive Users

NCT07651800
View directory record Official record
Conditions
Energy Deficiency Due to Short-term Fasting, Hormonal Contraception
Interventions
Energy Deficiency of approximately ~250 kcal/day
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Jun 25, 2026, 10:45 PM EDT
Not listed Phase 2 Interventional Accepts healthy volunteers

Oral Versus Patch Hormonal Contraceptive Effects on Metabolism, Clotting, Inflammatory Factors and Vascular Reactivity

NCT00439972
View directory record Official record
Conditions
Contraception
Interventions
Ortho-Cyclen (R), Ortho Evra (R), extended use of Ortho Evra (R)
Drug
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2011
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 13, 2011 · Synced Jun 25, 2026, 10:45 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Safety, Efficacy, Tolerability and Pharmacokinetics of LF111 (Drospirenone 4.0 mg) During 13 Cycles

NCT02269241
View directory record Official record
Conditions
Contraception
Interventions
LF111 (drospirenone)
Drug
Lead sponsor
Laboratories Leon Farma, S.A.
Industry
Eligibility
15 Years and older · Female only
Enrollment
1,552 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
37
States / cities
Birmingham, Alabama • Anaheim, California • Costa Mesa, California + 32 more
Source: ClinicalTrials.gov public record
Updated Aug 5, 2019 · Synced Jun 25, 2026, 10:45 PM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Effects of NLS-133, a Potential Non-Hormonal "On-Demand" Male Contraceptive

NCT07393334
View directory record Official record
Conditions
Male Contraception, Semen Volume, Sperm Motility
Interventions
NLS-133, Placebo, Active Comparator #1
Drug
Lead sponsor
Next Life Sciences
Industry
Eligibility
18 Years to 55 Years · Male only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Jun 25, 2026, 10:45 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Contraceptive Hormones, Immunity, and Microbiome Evaluation

NCT03660046
View directory record Official record
Conditions
Hormonal Contraception
Interventions
Depot medroxyprogesterone acetate (DMPA), Etonogestrel implant (Eng-Implant), Levonorgestrel IUD (Lng-IUD)
Drug
Lead sponsor
Emory University
Other
Eligibility
Up to 45 Years · Female only
Enrollment
155 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
3
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 28, 2024 · Synced Jun 25, 2026, 10:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Hormonal Birth Control and the Risk of Acquiring HIV

NCT00006324
View directory record Official record
Conditions
HIV Infections
Interventions
Ethinyl estradiol/levonorgestrel, Medroxyprogesterone acetate
Drug
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
16 Years to 35 Years · Female only
Enrollment
6,360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2002
U.S. locations
1
States / cities
Research Triangle Park, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 6, 2008 · Synced Jun 25, 2026, 10:45 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Contraceptive Efficacy Study of Ovaprene

NCT06127199
View directory record Official record
Conditions
Contraception
Interventions
Ovaprene
Device
Lead sponsor
Daré Bioscience, Inc.
Industry
Eligibility
18 Years to 40 Years · Female only
Enrollment
656 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
27
States / cities
Phoenix, Arizona • Scottsdale, Arizona • Tucson, Arizona + 24 more
Source: ClinicalTrials.gov public record
Updated May 10, 2026 · Synced Jun 25, 2026, 10:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Trial of Immediate Versus Delayed Initiation of Transdermal Hormonal Contraception After Therapeutic Abortion

NCT00235547
View directory record Official record
Conditions
Abortion
Interventions
timing of initiation of transdermal patch after an abortion
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
13 Years to 45 Years · Female only
Enrollment
298 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2012
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 28, 2019 · Synced Jun 25, 2026, 10:45 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Nexplanon and Combined Oral Contraceptive (COC) Combined Use Study

NCT02852265
View directory record Official record
Conditions
Contraception
Interventions
Etonogestrel contraceptive implant
Drug
Lead sponsor
University of California, Davis
Other
Eligibility
16 Years to 35 Years · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Dec 27, 2018 · Synced Jun 25, 2026, 10:45 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Depo-Provera: Bone Mineral Density and Total Body Calcium in Adolescent DP150CI Users and Non-Hormonal Contraception

NCT00139685
View directory record Official record
Conditions
Contraception, Bone Density
Interventions
Depo-Provera Contraceptive Injection - DP150CI
Drug
Lead sponsor
Pfizer
Industry
Eligibility
12 Years to 18 Years · Female only
Enrollment
350 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1998 – 2007
U.S. locations
12
States / cities
Los Angeles, California • Palo Alto, California • Torrance, California + 9 more
Source: ClinicalTrials.gov public record
Updated Sep 24, 2008 · Synced Jun 25, 2026, 10:45 PM EDT
Completed Not applicable Interventional

Cluster, Randomized Trial on Long Acting Reversible Contraception (LARC) Education and Training

NCT01360216
View directory record Official record
Conditions
Contraception Behavior
Interventions
LARC education and training
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 25 Years · Female only
Enrollment
1,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 13, 2020 · Synced Jun 25, 2026, 10:45 PM EDT
Withdrawn Phase 2 Interventional Accepts healthy volunteers

ITT-5 Mechanisms of Spermatogenesis in Man

NCT02147964
View directory record Official record
Conditions
Gonadotropin Deficiency
Interventions
Testosterone 1% Gel, Acyline, Dutasteride, Ketoconazole, HCG, placebo dutasteride, placebo ketoconazole
Drug
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 55 Years · Male only
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 17, 2019 · Synced Jun 25, 2026, 10:45 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

A Multicenter, Non-Comparative Trial on the Contraceptive Efficacy, Safety, and Tolerability of LPRI-424, 13 Cycles

NCT03945513
View directory record Official record
Conditions
Contraception
Interventions
LPRI424 (dienogest/ethinylestradiol)
Drug
Lead sponsor
Insud Pharma
Industry
Eligibility
13 Years to 45 Years · Female only
Enrollment
1,034 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Savannah, Georgia
Source: ClinicalTrials.gov public record
Updated Nov 13, 2023 · Synced Jun 25, 2026, 10:45 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Modulation of Immunity by Hormonal Contraceptives

NCT02011711
View directory record Official record
Conditions
Contraception
Interventions
Not listed
Lead sponsor
Thomas L. Cherpes
Other
Eligibility
15 Years to 25 Years · Female only
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jan 15, 2017 · Synced Jun 25, 2026, 10:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Improving Adolescent Adherence to Hormonal Contraception

NCT00584038
View directory record Official record
Conditions
Contraception
Interventions
educational instruction and phone follow-up, educational instruction in clinic
Behavioral
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
16 Years to 24 Years · Female only
Enrollment
1,155 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2012
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated May 23, 2013 · Synced Jun 25, 2026, 10:45 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Male Hormonal Contraceptive Development-ACY-5

NCT00161447
View directory record Official record
Conditions
Contraception
Interventions
Acyline, Testosterone Gel, Depo-Medroxyprogesterone
Drug
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 55 Years · Male only
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2006
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 18, 2008 · Synced Jun 25, 2026, 10:45 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Two-part Trial Assessing the Effects of 7α-methyl-19-nortestosterone (MENT) on Blood Pressure in Normal Men: an Open-label Pilot Study Followed by a Randomized, Double-blind, Placebo-controlled Study

NCT00812630
View directory record Official record
Conditions
Blood Pressure
Interventions
MENT or placebo
Drug
Lead sponsor
Population Council
Other
Eligibility
18 Years to 40 Years · Male only
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 14, 2017 · Synced Jun 25, 2026, 10:45 PM EDT
Terminated Phase 3 Interventional Results available

Contraceptive Efficacy and Safety of NOMAC-E2 Combined Oral Contraceptive

NCT05264506
View directory record Official record
Conditions
Contraception
Interventions
NOMAC-E2 COC
Drug
Lead sponsor
Organon and Co
Industry
Eligibility
14 Years to 35 Years · Female only
Enrollment
3,055 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
103
States / cities
Birmingham, Alabama • Dothan, Alabama • Mobile, Alabama + 79 more
Source: ClinicalTrials.gov public record
Updated Nov 20, 2025 · Synced Jun 25, 2026, 10:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of St. John's Wort on the Effectiveness of Oral Contraceptives

NCT00026013
View directory record Official record
Conditions
Contraception
Interventions
hypericum perforatum
Drug
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
18 Years to 40 Years · Female only
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2004
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 17, 2006 · Synced Jun 25, 2026, 10:45 PM EDT
Recruiting Not applicable Interventional

Hormonal Contraception Access Through Pharmacist Prescribing Implementation

NCT06823037
View directory record Official record
Conditions
Contraception, Pharmaceutical Services, Access and Linkage to Healthcare, Technology Use
Interventions
HAPPI software
Other
Lead sponsor
EMPOWERX INC
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Del Mar, California
Source: ClinicalTrials.gov public record
Updated Dec 3, 2025 · Synced Jun 25, 2026, 10:45 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Does Concomitant Use of Combined Oral Hormonal Steroids Stop Bleeding in Women Using Etonogestrel Implants (Implanon/Nexplanon®)?: A Randomized Controlled Study

NCT01968135
View directory record Official record
Conditions
Uterine Hemorrhage, Contraception
Interventions
Combined Oral Contraceptive Pill, Placebo Sugar Pill
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 44 Years · Female only
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated May 4, 2016 · Synced Jun 25, 2026, 10:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Hormonal Contraception and Vaginal Health

NCT00612508
View directory record Official record
Conditions
Contraceptive Usage, Vaginal Epithelial Disruption
Interventions
Desogen (ethinyl estradiol and desogestrel), NuvaRing (ethinyl estradiol and etonogestrel)
Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 7, 2012 · Synced Jun 25, 2026, 10:45 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Combined Hormonal Contraceptive Use in High Risk Women: A Longitudinal Study

NCT00361400
View directory record Official record
Conditions
Pregnancy
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
15 Years to 24 Years · Female only
Enrollment
1,387 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2008
U.S. locations
5
States / cities
Hayward, California • Oakland, California • Richmond, California + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 1, 2013 · Synced Jun 25, 2026, 10:45 PM EDT