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ClinicalTrials.gov public records Last synced Sep 8, 2026, 11:03 AM EDT

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Showing 1–24 of 62 matching trials from the live ClinicalTrials.gov search.
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Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Effects of Pulse Consumption, Gut Microbiome, and Appetite in Healthy Participants

NCT07043712
Conditions
Microbial Colonization, Metabolic Syndrome
Interventions
High pulse consumption
Dietary Supplement
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
20 Years to 55 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Columbia, Missouri
Conditions
Gut Microbiome
Interventions
Dietary MACs, Control
Dietary Supplement · Other
Lead sponsor
Access Business Group
Industry
Eligibility
40 Years to 60 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Addison, Illinois
Completed Not applicable Interventional Accepts healthy volunteers

Predicting Adenomatous Polyps in the Colon Using Images of a Human Tongue

NCT06305364
Conditions
Colorectal Neoplasms, Gastrointestinal Microbiome
Interventions
Gixam
Device
Lead sponsor
Jubaan Ltd.
Industry
Eligibility
18 Years to 75 Years
Enrollment
426 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
3
States / cities
New York, New York
Completed Not applicable Interventional Accepts healthy volunteers Results available

Systems Biology of Flu Vaccine in Healthy Adults With and Without the Use of Antibiotics

NCT02154061
Conditions
Influenza
Interventions
IIV Flu Vaccine, Metronidazole, Neomycin, Vancomycin
Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years to 40 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Atlanta, Georgia
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of S. Boulardii and Amoxicillin/Clavulanate on Gut Microbiota

NCT01473368
Conditions
Healthy Volunteers
Interventions
Saccharomyces boulardii, Amoxicillin Clavulanate
Dietary Supplement · Drug
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers

A Study to Evaluate the Influence of Diet on GI Health

NCT04783142
Conditions
Healthy
Interventions
High-fiber, low-protein diet, Low-fiber, high-protein diet
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
2
States / cities
Rochester, Minnesota
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Impact of Dietary Intervention on Inflammation and Microbiome Composition Post-Colonoscopy

NCT06603519
Conditions
Colorectal Polyp, Inflammation, Dietary Intervention, Microbiota, Colorectal Neoplasms, Metabolomics
Interventions
Modified Plant-Based Mediterranean Diet
Dietary Supplement
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
San Diego, California
Conditions
Malignant Central Nervous System Neoplasm
Interventions
Non-Interventional Study
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
Jacksonville, Florida
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers

Effects of Xylooligosarcharide on Composition of the Human Colonic Microflora

NCT01861964
Conditions
Bifidobacteria, Healthy Volunteers
Interventions
Placebo (Maltodextrin), Xylooligosarcharide 1.4g, Xylooligosarcharide 2.8g
Dietary Supplement
Lead sponsor
University of California, Los Angeles
Other
Eligibility
20 Years to 50 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
2
States / cities
Los Angeles, California
Completed Not applicable Interventional Results available

Impacts of Lentils on Metabolism and Inflammation

NCT04283448
Conditions
Hypertriglyceridemia, Inflammation, Waist, Hypertriglyceridemic
Interventions
Dietary Lentil, Control
Behavioral
Lead sponsor
Montana State University
Other
Eligibility
18 Years to 70 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Bozeman, Montana
Conditions
Gut Microbiota
Interventions
Dietary Fiber, Placebo
Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 45 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Davis, California
Completed No phase listed Observational Accepts healthy volunteers

Genomic Tools for Studying the Ecology of the Human Vaginal Microflora

NCT00576797
Conditions
Healthy
Interventions
Not listed
Lead sponsor
Emory University
Other
Eligibility
12 Years to 45 Years · Female only
Enrollment
396 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
3
States / cities
Atlanta, Georgia • Baltimore, Maryland
Completed Not applicable Interventional Accepts healthy volunteers

Adult HMO Supplementation and the Gut Microbiome

NCT06570330
Conditions
Healthy Adults
Interventions
SuperHMO, Non-GMO corn Maltodextrin, Rapid Absorption
Dietary Supplement
Lead sponsor
Seeding Inc
Industry
Eligibility
18 Years to 40 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Rockville, Maryland
Completed Not applicable Interventional Accepts healthy volunteers

Trimethylamine-N-oxide Production and Metabolism

NCT02558673
Conditions
Healthy
Interventions
TMAO dietary precursors, Control (or active comparator)
Other
Lead sponsor
Cornell University
Other
Eligibility
21 Years to 50 Years · Male only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
2
States / cities
Ithaca, New York
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Grape Impact on Human Gut Microbiome

NCT07797803
Conditions
Gut Microbiomes
Interventions
Grape Powder, Placebo Powder
Dietary Supplement · Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
45 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Accepts healthy volunteers

Oral Pomegranate Extract on the Microbiome and Skin Biophysical Properties

NCT04596722
Conditions
Human Microbiome
Interventions
Pomella, Placebo
Dietary Supplement · Other
Lead sponsor
Integrative Skin Science and Research
Industry
Eligibility
25 Years to 55 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Sacramento, California
Completed Not applicable Interventional Accepts healthy volunteers

Resistant Starch Wheat for Improved Metabolic Health

NCT03082131
Conditions
Gut Microbiota, Metabolism, Metabolic Health
Interventions
Resistant Starch Wheat
Dietary Supplement
Lead sponsor
USDA, Western Human Nutrition Research Center
Federal
Eligibility
40 Years to 65 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Davis, California
Completed Not applicable Interventional Accepts healthy volunteers

Human Gut Microbiota and Prebiotic Response

NCT03595306
Conditions
Healthy Gut Microbiota
Interventions
Prebiotic A - inulin, Prebiotic B - galactooligosaccharides(GOS), Prebiotic C - wheat dextrin
Dietary Supplement
Lead sponsor
Duke University
Other
Eligibility
17 Years to 70 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Durham, North Carolina
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Association Between Gut Microbiome and Dietary Determinants and Vaccine Response

NCT05239403
Conditions
Influenza
Interventions
Biospecimen Collection, Questionnaire Administration
Procedure · Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
74 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Houston, Texas
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Quest to Analyze One Thousand Humans Meditating

NCT06583395
Conditions
Amyotrophic Lateral Sclerosis (ALS), Angina, Stable, Anxiety, Asthma, Atrial Fibrillation, Cancer Brain, Cancer, Breast, Cancer Colon, Cancer, Lung, Cancer, Ovarian, Cancer Prostate, Cancer Skin, Throat Cancer, Lymphoma, Cancer, Thyroid, Cancer, Other, Cerebral Palsy, Chronic Fatigue Syndrome, Cluster Headache, Chronic Obstructive Pulmonary Disease (COPD), Chronic Kidney Diseases, Crohn Disease, Deafness, Depression, Diabetes, Eczema, Epilepsy, Fibroids, Fibromyalgia, Heart Failure, Hypertension, Hyperthyroidism, Hypothyroidism, Irritable Bowel Syndrome (IBS), Infertility, Lyme Disease, Macular Degeneration, Migraine, Multiple Allergies, Multiple Sclerosis, Osteoarthritis, Osteoporosis, Ovarian Cysts, Parkinson Disease, Phantom Limb Pain, Psoriasis, Post Traumatic Stress Disorder (PTSD), Rheumatoid Arthritis, Sjogrens Disease, Spinal Cord Injury, Spinal Stenosis, Stroke, Tension Headache, Tinnitus, Ulcerative Colitis
Interventions
Advanced multi-component meditation practice
Behavioral
Lead sponsor
Tobias Moeller-Bertram
Industry
Eligibility
21 Years and older
Enrollment
3,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Palm Desert, California
Not listed Not applicable Interventional Accepts healthy volunteers

Garden-fresh Foods and Gut Microbiomes

NCT06506786
Conditions
Gut Microbiome
Interventions
Garden-fresh Produce, Supermarket Produce
Other
Lead sponsor
University of Oregon
Other
Eligibility
18 Years to 45 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Eugene, Oregon
Completed Not applicable Interventional Accepts healthy volunteers

Impacts of Fruit on the Gut Health and Human Health

NCT05063929
Conditions
Cardiometabolic Health, Healthy Aging, Cognition
Interventions
Fruit (2 cup eq), Fruit restriction (1/2 cup eq)
Other
Lead sponsor
San Diego State University
Other
Eligibility
30 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
San Diego, California
Conditions
Insulin Sensitivity, Overweight or Obesity, Inflammatory Response
Interventions
Control, Black bean, Chickpea
Other
Lead sponsor
Clinical Nutrition Research Center, Illinois Institute of Technology
Industry
Eligibility
18 Years and older
Enrollment
103 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Completed Not applicable Interventional Accepts healthy volunteers

Food Effects on the Gut Microbiota

NCT03078283
Conditions
Gut Microbial Responses to Dietary Fiber
Interventions
high-fiber food type
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
31 Years to 45 Years · Female only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
St Louis, Missouri