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ClinicalTrials.gov public records Last synced Oct 11, 2026, 12:48 PM EDT

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Showing 73–96 of 766 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Human Immunodeficiency Virus (HIV) Prophylaxis Clear all
Completed Not applicable Interventional

The Safety and Effectiveness of Ganciclovir Plus Interferon Beta in Preventing the Return of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS

NCT00002299
View directory record Official record
Conditions
Cytomegalovirus Retinitis, HIV Infections
Interventions
Interferon beta-1b, Ganciclovir
Drug
Lead sponsor
Hoffmann-La Roche
Industry
Eligibility
18 Years to 60 Years
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
6
States / cities
Los Angeles, California • Orange, California • San Diego, California + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 24, 2005 · Synced Oct 11, 2026, 12:48 PM EDT
Recruiting Not applicable Interventional

RESTORE Study R61 Phase: Recovery and Engagement for Stimulant Users on Re-entry

NCT07136363
View directory record Official record
Conditions
HIV, Stimulant Use Disorder, Justice Involved Populations, HIV Prevention
Interventions
DynamiCare, Patient Navigation (PN)
Device · Behavioral
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
New Haven, Connecticut • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Oct 11, 2026, 12:48 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Feasibility, Acceptability, and Preliminary Efficacy of an HIV Prevention Intervention for Older Black Women

NCT07181616
View directory record Official record
Conditions
Health Risk Behaviors
Interventions
Adapted W2W, Waitlist Control
Behavioral
Lead sponsor
Laneshia Conner
Other
Eligibility
50 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Oct 11, 2026, 12:48 PM EDT
Completed Phase 2 Interventional

The Safety and Effectiveness of Ganciclovir in the Prevention of Cytomegalovirus (CMV) of the Eyes and Disease of the Stomach and Intestines in Patients With HIV

NCT00001034
View directory record Official record
Conditions
Cytomegalovirus Retinitis, HIV Infections, Gastrointestinal Diseases
Interventions
Ganciclovir
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
13 Years and older
Enrollment
850 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 1995
U.S. locations
17
States / cities
San Francisco, California • Denver, Colorado • Wilmington, Delaware + 12 more
Source: ClinicalTrials.gov public record
Updated Nov 4, 2021 · Synced Oct 11, 2026, 12:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mitigating Sexual Stigma Within Healthcare Interactions Improve Engagement of MSM in HIV Prevention

NCT04779736
View directory record Official record
Conditions
Human Immunodeficiency Virus, Stigma, Social, Patient Engagement
Interventions
A set of implementation strategies to reduce sexual stigma
Behavioral
Lead sponsor
Albert Einstein College of Medicine
Other
Eligibility
18 Years and older
Enrollment
113 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated May 29, 2025 · Synced Oct 11, 2026, 12:48 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Study of MK-8527 in Healthy Lactating Female Participants (MK-8527-009)

NCT06580587
View directory record Official record
Conditions
Healthy, HIV Pre-exposure Prophylaxis
Interventions
MK-8527
Drug
Lead sponsor
Merck Sharp & Dohme LLC
Industry
Eligibility
18 Years and older · Female only
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
2
States / cities
Springfield, Missouri • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Oct 11, 2026, 12:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Gender-Specific Combination HIV Prevention for Youth in High Burden Settings (MP3-Youth)

NCT01571128
View directory record Official record
Conditions
HIV, Adolescent Behavior, Gender
Interventions
Male-Specific Intervention Package, Female-Specific Intervention Package, Pre-Exposure Prophylaxis (Females), Cash Transfer Cohort (Females)
Other · Drug · Behavioral
Lead sponsor
New York University
Other
Eligibility
15 Years to 24 Years
Enrollment
1,215 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 18, 2022 · Synced Oct 11, 2026, 12:48 PM EDT
Completed Not applicable Interventional

Brief HIV Prevention Counseling for STI Patients in South Africa

NCT01242501
View directory record Official record
Conditions
Sexually Transmitted Infections
Interventions
60 Minute HIV/STI risk reduction counseling.Single 60 min Social Cognitive Theory-based counseling., 20-Min education session
Behavioral
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years and older
Enrollment
1,050 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Storrs, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 11, 2021 · Synced Oct 11, 2026, 12:48 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Maintaining HIV Prevention Gains in Female Adolescents

NCT00161343
View directory record Official record
Conditions
HIV Infection, Sexually Transmitted Diseases
Interventions
Health Improvement Project for Teens on HIV Prevention
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
15 Years to 19 Years · Female only
Enrollment
640 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2009
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Sep 6, 2012 · Synced Oct 11, 2026, 12:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mobile Messaging Intervention to Present New HIV Prevention Options for Men Who Have Sex With Men (MSM)

NCT03666247
View directory record Official record
Conditions
Human Immunodeficiency Virus
Interventions
HealthMindr Application, Waitlist
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years and older · Male only
Enrollment
1,229 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
3
States / cities
Atlanta, Georgia • Detroit, Michigan • New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 6, 2020 · Synced Oct 11, 2026, 12:48 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Pre-Exposure Prophylaxis (PrEP)- Gender Affirming Hormone Therapy (GAHT) Interactions in TGW

NCT04760691
View directory record Official record
Conditions
HIV, Prophylaxis, Transgender
Interventions
Truvada alone, Truvada plus Leuprolide 11.25mg intramuscular injection, Truvada plus Estradiol 1 mg, Truvada plus Estradiol 6 mg, Estradiol 6 mg alone
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older · Male only
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Oct 11, 2026, 12:48 PM EDT
Recruiting Not applicable Interventional

Quitting Matters Human Immunodeficiency Virus Hybrid Trial

NCT06883097
View directory record Official record
Conditions
Tobacco, Tobacco Abstinence, Smoking Cessation, Smoking Cessation; Tobacco Dependence, Human Immunodeficiency Virus (HIV), Tobacco Dependence Caused by Cigarettes, Cancer Prevention
Interventions
Learn to Quit-HIV (LTQ-H) App, QuitStart
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
314 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 11, 2026, 12:48 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

HIV/STI/HCV Testing and Overdose Prevention Among Survivors of Sex Trafficking

NCT07264582
View directory record Official record
Conditions
HIV Testing, STI, HCV, Overdose, Drug
Interventions
Sex Trafficking Survivor-Developed Digital Crowdsourced Intervention
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older · Female only
Enrollment
368 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced Oct 11, 2026, 12:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Enhancing PrEP in Community Settings (EPIC)

NCT02371525
View directory record Official record
Conditions
HIV
Interventions
Prepmate
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 29 Years · Male only
Enrollment
121 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 26, 2017 · Synced Oct 11, 2026, 12:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Developing a Dyadic Intervention for Sexually Transmitted Infection (STI)/HIV Prevention in Youth

NCT03275168
View directory record Official record
Conditions
Exposure to Sexually Transmissible Disorder (Event)
Interventions
Intervention, Individual evidence-based STI/HIV prevention intervention
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
16 Years to 30 Years
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 9, 2025 · Synced Oct 11, 2026, 12:48 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

The HJ MILE HIV Prevention Intervention for Post-incarcerated Men

NCT01427543
View directory record Official record
Conditions
HIV, Risk Reduction Behavior
Interventions
MILE intervention
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older · Male only
Enrollment
212 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 12, 2018 · Synced Oct 11, 2026, 12:48 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Case Management Dyad

NCT06162897
View directory record Official record
Conditions
HIV, Pre-exposure Prophylaxis, Case Management, Contingency Management
Interventions
Dyadic Case Management
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
220 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 11, 2026, 12:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

PC4PrEP: Integrating PrEP Into Primary Care

NCT03617874
View directory record Official record
Conditions
Human Immunodeficiency Virus Transmission
Interventions
PC4PrEP- Intervention Clinics, Standard of Care Clinics
Other
Lead sponsor
Albert Einstein College of Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Sep 16, 2022 · Synced Oct 11, 2026, 12:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Prison Connect-STI/HIV Prevention Intervention for Couples Affected by Incarceration

NCT03025191
View directory record Official record
Conditions
Incarceration
Interventions
Speaker/Listener technique, Social Support, Problem-Solving, Goal Setting
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 14, 2017 · Synced Oct 11, 2026, 12:48 PM EDT
Recruiting Phase 4 Interventional

Long-acting Cabotegravir Injectable Pre-exposure Prophylaxis for People Who Inject Drugs

NCT07199335
View directory record Official record
Conditions
HIV, Substance Use Disorder (SUD), Injection Drug Use
Interventions
APRETUDE (cabotegravir)
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Oct 11, 2026, 12:48 PM EDT
Not listed Phase 3 Interventional Accepts healthy volunteers

Video-Based Delivery of HIV Test Information for Spanish-Speaking Latinos

NCT01452555
View directory record Official record
Conditions
HIV, AIDS
Interventions
Video or In-Person Presentation
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
18 Years to 64 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2011
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 17, 2011 · Synced Oct 11, 2026, 12:48 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

IN-US-276-1340: Pre-Exposure Prophylaxis to Prevent HIV Acquisition in US Women: A Demonstration Project

NCT03058835
View directory record Official record
Conditions
PrEP Adherence Monitoring
Interventions
tenofovir disoproxil and emtricitabine
Drug
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 64 Years · Female only
Enrollment
162 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2024
U.S. locations
4
States / cities
Atlanta, Georgia • Chicago, Illinois • Newark, New Jersey + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Oct 11, 2026, 12:48 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

HIV Prevention for Youth With Severe Mental Illness

NCT00496691
View directory record Official record
Conditions
HIV Infections
Interventions
Family-based HIV prevention program
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
13 Years to 18 Years
Enrollment
718 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2010
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 20, 2016 · Synced Oct 11, 2026, 12:48 PM EDT
Completed Not applicable Interventional

HIV Prevention and Trauma Treatment for Men Who Have Sex With Men With Childhood Sexual Abuse Histories

NCT01395979
View directory record Official record
Conditions
Sexual Risk Behavior, Childhood Sexual Abuse, Stress Disorders, Post-Traumatic
Interventions
Cognitive Processing Therapy for Sexual Risk, Supportive Psychotherapy, Sexual Risk Reduction Intervention
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older · Male only
Enrollment
232 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
3
States / cities
Coral Gables, Florida • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 30, 2018 · Synced Oct 11, 2026, 12:48 PM EDT