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Showing 1–24 of 752 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Human Immunodeficiency Virus Prevention Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comprehensive HIV Prevention Package for MSM in Southern Africa: Pilot Study (Sibanye Health Project)

NCT02043015
View directory record Official record
Conditions
HIV
Interventions
Condom choices, Condom-compatible lubricant choices, Couples HIV counseling and testing (CVCT), Pre-exposure prophylaxis with FTC/TDF, Staff and provider MSM and LGBT sensitization training, HIV Testing and Risk-reduction counseling, Linkage to care
Behavioral · Drug · Other
Lead sponsor
Emory University
Other
Eligibility
18 Years and older · Male only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
2
States / cities
Atlanta, Georgia • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 16, 2018 · Synced Jun 26, 2026, 10:15 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Scalable Interventions to Increase PrEP Adherence: Value Affirmation and Future Selves

NCT03278990
View directory record Official record
Conditions
HIV Prevention
Interventions
Value Affirmation and Future Selves Combination, Control writing exercise
Behavioral
Lead sponsor
Stuart Fisk
Other
Eligibility
18 Years to 65 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 10, 2021 · Synced Jun 26, 2026, 10:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

ASAP: Access to Syringes at Pharmacies for the Prevention of Bloodborne Infections Among People Who Inject Drugs

NCT05270135
View directory record Official record
Conditions
Skin and Soft Tissue Infections, Hiv, Hepatitis C, Bloodstream Infection
Interventions
ASAP
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Dec 18, 2023 · Synced Jun 26, 2026, 10:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Enhancing PrEP in Community Settings (EPIC)

NCT02371525
View directory record Official record
Conditions
HIV
Interventions
Prepmate
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 29 Years · Male only
Enrollment
121 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 25, 2017 · Synced Jun 26, 2026, 10:15 PM EDT
Completed Not applicable Interventional

RCT of an Integrative Intervention for Non-Treatment-Seeking Meth Users

NCT01926184
View directory record Official record
Conditions
HIV/AIDS, Stimulant Use Disorders
Interventions
Affect Regulation Treatment to Enhance Meth Intervention Success (ARTEMIS), Contingency Management (CM)
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Male only
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 20, 2022 · Synced Jun 26, 2026, 10:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Supporting Trans Affirmation, Relationships, and Sex, Phase 3

NCT06001307
View directory record Official record
Conditions
HIV, Violence, Gender-Based, Violence, Domestic, Risk Reduction Behavior
Interventions
Program STARS (Supporting Trans Affirmation, relationships, and Sex), Relaxation and Stress Reduction
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older · Male only
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Nov 18, 2025 · Synced Jun 26, 2026, 10:15 PM EDT
Completed Phase 2 Interventional

HIV Prevention Intervention for Couples

NCT00325585
View directory record Official record
Conditions
Acquired Immunodeficiency Syndrome
Interventions
Couples HIV counseling and testing, Women's relationship-focused HIV counseling and testing
Behavioral
Lead sponsor
National Development and Research Institutes, Inc.
Other
Eligibility
18 Years and older
Enrollment
780 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Apr 8, 2013 · Synced Jun 26, 2026, 10:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluating a Structural and Behavioral HIV Risk Reduction Program for Black Men

NCT01694121
View directory record Official record
Conditions
HIV
Interventions
MEN Count, Comparison
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 40 Years · Male only
Enrollment
455 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Dec 27, 2018 · Synced Jun 26, 2026, 10:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The LEARN Study for CVD Prevention

NCT05242952
View directory record Official record
Conditions
Cardiovascular Diseases
Interventions
Gaming in a virtual environment
Behavioral
Lead sponsor
Yale University
Other
Eligibility
30 Years to 65 Years · Male only
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Orange, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 27, 2025 · Synced Jun 26, 2026, 10:15 PM EDT
Recruiting Not applicable Interventional

PRIDE III Prison Interventions and HIV Prevention Collaboration

NCT06962033
View directory record Official record
Conditions
Hiv, Opioid Use
Interventions
Opioid Agonist Therapy
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 10, 2025 · Synced Jun 26, 2026, 10:15 PM EDT
Completed Phase 2 Interventional Results available

Rituximab and Combination Chemotherapy in Treating Patients With Newly Diagnosed, HIV-Associated Burkitt's Lymphoma

NCT00392834
View directory record Official record
Conditions
Lymphoma
Interventions
filgrastim, pegfilgrastim, rituximab, cyclophosphamide, cytarabine, doxorubicin hydrochloride, etoposide, ifosfamide, leucovorin calcium, liposomal cytarabine, methotrexate, therapeutic hydrocortisone, vincristine sulfate
Biological · Drug
Lead sponsor
AIDS Malignancy Consortium
Network
Eligibility
18 Years to 120 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
13
States / cities
La Jolla, California • Los Angeles, California • San Francisco, California + 9 more
Source: ClinicalTrials.gov public record
Updated Jun 5, 2018 · Synced Jun 26, 2026, 10:15 PM EDT
Recruiting Not applicable Interventional

RESTORE Study R61 Phase: Recovery and Engagement for Stimulant Users on Re-entry

NCT07136363
View directory record Official record
Conditions
HIV, Stimulant Use Disorder, Justice Involved Populations, HIV Prevention
Interventions
DynamiCare, Patient Navigation (PN)
Device · Behavioral
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
New Haven, Connecticut • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jun 14, 2026 · Synced Jun 26, 2026, 10:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Pragmatic Clinical Trial of MyPEEPS Mobile to Improve HIV Prevention Behaviors in Diverse Adolescent MSM

NCT03167606
View directory record Official record
Conditions
HIV Infections
Interventions
MyPEEPS Mobile
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
13 Years to 18 Years · Male only
Enrollment
764 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
4
States / cities
Birmingham, Alabama • Chicago, Illinois • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 22, 2023 · Synced Jun 26, 2026, 10:15 PM EDT
Not yet recruiting Phase 2 Interventional Accepts healthy volunteers

Combatting HIV Or Other STIs Early (CHOOSE)

NCT07510048
View directory record Official record
Conditions
HIV, STIs, STIs Prevention, HIV Prevention
Interventions
Standard of care and PrEP Choice at Enrollment, Standard of care followed by PrEP Choice at Month 9
Other
Lead sponsor
Westat
Other
Eligibility
13 Years to 24 Years · Male only
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
6
States / cities
San Francisco, California • Washington D.C., District of Columbia • Tampa, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Jun 26, 2026, 10:15 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Prepping for The Talk: Helping Trusted Adults and Youth Talk About Sexual Health

NCT07011563
View directory record Official record
Conditions
HIV Prevention, Sexual Health
Interventions
Intervention, Control
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
14 Years to 17 Years · Male only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 8, 2025 · Synced Jun 26, 2026, 10:15 PM EDT
Completed Not applicable Interventional

A Randomized, Prospective, Double-Blind Study Comparing Fluconazole With Placebo for Primary and Secondary Prophylaxis of Mucosal Candidiasis in HIV-Infected Women

NCT00000744
View directory record Official record
Conditions
Candidiasis, Candidiasis, Esophageal, HIV Infections
Interventions
Fluconazole
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
13 Years and older · Female only
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 1995
U.S. locations
16
States / cities
San Francisco, California • Denver, Colorado • Wilmington, Delaware + 11 more
Source: ClinicalTrials.gov public record
Updated Nov 2, 2021 · Synced Jun 26, 2026, 10:15 PM EDT
Completed Not applicable Interventional

Safer Choices 2 - HIV, STD, & Pregnancy Prevention Program

NCT00223314
View directory record Official record
Conditions
HIV, Sexually Transmitted Diseases, Pregnancy, HIV Infections
Interventions
HIV, STD, Pregnancy Prevention Curriculum
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
Not listed
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2004
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 20, 2007 · Synced Jun 26, 2026, 10:15 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Behavioral Economic Intervention to Improve HIV Behaviors in Sexual Minority Individuals

NCT06745947
View directory record Official record
Conditions
HIV Prevention
Interventions
EFT
Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 34 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jun 21, 2025 · Synced Jun 26, 2026, 10:15 PM EDT
Active, not recruiting Phase 4 Interventional Accepts healthy volunteers

Emtricitabine/Tenofovir Alafenamide Switch Study for Transgender Individuals for HIV Pre-exposure Prophylaxis

NCT04616963
View directory record Official record
Conditions
Hiv, Hormone Therapy
Interventions
Emtricitabine / Tenofovir Disoproxil Oral Tablet 200/300 mg, Emtricitabine Tenofovir Alafenamide 200/25 mg
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated May 5, 2023 · Synced Jun 26, 2026, 10:15 PM EDT
Completed Not applicable Interventional

A Web-based Intervention Study to Reduce High-risk Sexual Behavior by Persons Living With HIV AIDS (PLWH)

NCT01198418
View directory record Official record
Conditions
Sexually Transmitted Infections, HIV Infections
Interventions
Experimental
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older · Male only
Enrollment
181 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2017
U.S. locations
3
States / cities
Los Angeles, California • San Diego, California • Torrance, California
Source: ClinicalTrials.gov public record
Updated May 11, 2020 · Synced Jun 26, 2026, 10:15 PM EDT
Completed Not applicable Interventional

Positive Lifestyles Using Safety

NCT00836290
View directory record Official record
Conditions
HIV, HIV Infections
Interventions
Pre-Release (Group 1), Post-release (Group 2)
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 20, 2015 · Synced Jun 26, 2026, 10:15 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

The PROTECT (PrEP Optimization Through Telehealth Care and Treatment) Trial

NCT06845774
View directory record Official record
Conditions
HIV Prevention
Interventions
CDC PrEP with active referral, TelePrEP
Behavioral
Lead sponsor
Hilary L Surratt, PhD
Other
Eligibility
18 Years to 99 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Jun 26, 2026, 10:15 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Tenofovir Levels Following Local Application of Tenofovir Reduced-Glycerin 1% Gel

NCT01768962
View directory record Official record
Conditions
HIV Prevention
Interventions
Once Daily Application of TFV RG 1% Gel - Vaginal, Once Daily Application of TFV RG 1% gel - Rectal
Drug
Lead sponsor
CONRAD
Other
Eligibility
21 Years to 45 Years · Female only
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 27, 2021 · Synced Jun 26, 2026, 10:15 PM EDT
Not listed Not applicable Interventional

Linking Women to PrEP Care

NCT03281343
View directory record Official record
Conditions
Prevention
Interventions
Motivational Interviewing & Patient Navigator, Standard of Care (SOC)
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Apr 4, 2023 · Synced Jun 26, 2026, 10:15 PM EDT