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ClinicalTrials.gov public records Last synced Oct 24, 2026, 5:11 PM EDT

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Showing 625–648 of 765 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Human Immunodeficiency Virus Prevention Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

The OPENS Trial: Offering Women PrEP (Aim 1)

NCT04621760
View directory record Official record
Conditions
Human Immunodeficiency Virus Transmission, Sexually Transmitted Diseases
Interventions
HIV Prevention Decision Support Tool (DST), Standard Counseling
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 45 Years
Enrollment
189 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 31, 2026 · Synced Oct 24, 2026, 5:11 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

HIV, Abuse, and Psychiatric Disorders Among Youth

NCT00603369
View directory record Official record
Conditions
HIV Infections
Interventions
group intervention
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
13 Years to 19 Years
Enrollment
212 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2007
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Feb 6, 2009 · Synced Oct 24, 2026, 5:11 PM EDT
Enrolling by invitation Not applicable Interventional

Addressing Psychosocial Comorbidities in HIV Treatment and Prevention 2b

NCT05352061
View directory record Official record
Conditions
Medication Adherence, Mental Health Issue
Interventions
CBT for Syndemics and Adherence Factors
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jun 26, 2026 · Synced Oct 24, 2026, 5:11 PM EDT
Completed Phase 2 Interventional

A Study to Compare Different Drugs Used to Prevent Serious Bacterial Infections in HIV-Positive Children

NCT00000811
View directory record Official record
Conditions
Bacterial Infections, Pneumonia, Pneumocystis Carinii, HIV Infections
Interventions
Azithromycin, Atovaquone, Sulfamethoxazole-Trimethoprim
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
3 Months to 18 Months
Enrollment
690 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2001
U.S. locations
72
States / cities
Birmingham, Alabama • Mobile, Alabama • La Jolla, California + 46 more
Source: ClinicalTrials.gov public record
Updated Nov 4, 2021 · Synced Oct 24, 2026, 5:11 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

#ChopViolence/#ChopHIV

NCT04769492
View directory record Official record
Conditions
Violence, HIV
Interventions
#ChopViolence/#ChopHIV
Other
Lead sponsor
Hektoen Institute for Medical Research
Other
Eligibility
15 Years to 29 Years · Male only
Enrollment
525 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 1, 2024 · Synced Oct 24, 2026, 5:11 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Study of a Potential Preventive Vaccine Against HIV in Healthy Volunteers

NCT00545987
View directory record Official record
Conditions
HIV Infections
Interventions
TriGrid™ Delivery System, conventional intramuscular injection
Device
Lead sponsor
Rockefeller University
Other
Eligibility
18 Years to 60 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2011
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 5, 2011 · Synced Oct 24, 2026, 5:11 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Project RAP: Family-based HIV Prevention in the Juvenile Drug Court

NCT01403298
View directory record Official record
Conditions
HIV/AIDS
Interventions
Family-Based HIV prevention, Adolescent Only Health Promotion
Behavioral · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
13 Years to 18 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 12, 2020 · Synced Oct 24, 2026, 5:11 PM EDT
Completed Phase 3 Interventional

A Phase III Randomized, Double-Blind, Controlled Study of the Use of Anti-HIV Immune Serum Globulin (HIVIG) for the Prevention of Maternal-Fetal HIV Transmission in Pregnant Women and Newborns Receiving Zidovudine (AZT)

NCT00000751
View directory record Official record
Conditions
HIV Infections, Pregnancy
Interventions
Anti-HIV Immune Serum Globulin (Human), Globulin, Immune, Zidovudine
Drug
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
13 Years to 60 Years · Female only
Enrollment
1,600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2007
U.S. locations
48
States / cities
La Jolla, California • Los Angeles, California • San Francisco, California + 26 more
Source: ClinicalTrials.gov public record
Updated Sep 30, 2008 · Synced Oct 24, 2026, 5:11 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Evaluating The Acceptability and Uptake of Pre-Exposure Prophylaxis (PrEP) for Adolescent Women in The Deep South

NCT03897725
View directory record Official record
Conditions
Adolescent Behavior, HIV/AIDS, PrEP
Interventions
Telehealth Coaching
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
15 Years to 21 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Nov 12, 2021 · Synced Oct 24, 2026, 5:11 PM EDT
Recruiting Not applicable Interventional

Pre-exposure Prophylaxis (PrEP) Uptake and Adherence Intervention for Women with Trauma-related Conditions

NCT06558825
View directory record Official record
Conditions
Substance Use
Interventions
Integrated Intervention to Promote PrEP Uptake, Standard Treatment Condition
Behavioral · Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 30, 2024 · Synced Oct 24, 2026, 5:11 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Development of Adherence Biomarkers for Multiple Microbicide and Multipurpose Prevention Technology (MPT) Dosage Forms

NCT02569697
View directory record Official record
Conditions
HIV
Interventions
HEC Placebo gel, Placebo Intravaginal Ring, Placebo Vaginal Film, Placebo Vaginal Insert
Other
Lead sponsor
CONRAD
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 2, 2016 · Synced Oct 24, 2026, 5:11 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

LYNX: A Novel Mobile App to Support Linkage to HIV/STI Testing PrEP for Young Men Who Have Sex With Men

NCT03177512
View directory record Official record
Conditions
HIV, Sexually Transmitted Diseases, Risk Reduction, Pre-Exposure Prophylaxis
Interventions
LYNX Mobile App
Behavioral
Lead sponsor
Public Health Foundation Enterprises, Inc.
Other
Eligibility
15 Years to 24 Years · Male only
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
2
States / cities
Tampa, Florida • Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 11, 2021 · Synced Oct 24, 2026, 5:11 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Effectiveness of Communication Technology in Disseminating HIV Prevention Training to Non-governmental Organizations

NCT00698529
View directory record Official record
Conditions
HIV Infections
Interventions
Face-to-face training, Distance training, Popular Opinion Leader (POL)
Behavioral
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older
Enrollment
99 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2019
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 11, 2019 · Synced Oct 24, 2026, 5:11 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Rectal Insert TAF/EVG Pre-Exposure Prophylaxis (RITE PrEP) Study

NCT06274398
View directory record Official record
Conditions
Safety Issues
Interventions
TAF/EVG rectal insert, Matching placebo rectal insert
Drug
Lead sponsor
Eastern Virginia Medical School
Other
Eligibility
18 Years to 59 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 25, 2025 · Synced Oct 24, 2026, 5:11 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

HIV Prevention Among Latino MSM: Evaluation of a Locally Developed Intervention

NCT01626898
View directory record Official record
Conditions
Risk Reduction Behavior
Interventions
HOLA en Grupos, General Health intervention (comparison intervention )
Behavioral
Lead sponsor
Centers for Disease Control and Prevention
Federal
Eligibility
18 Years and older · Male only
Enrollment
304 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 3, 2016 · Synced Oct 24, 2026, 5:11 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Motiv82Change: an HIV Prevention Study for Young Latino Men

NCT00877695
View directory record Official record
Conditions
HIV Infections
Interventions
Entre Culturas: Navigating Culture, Identity, and HIV Risk
Behavioral
Lead sponsor
Nova Southeastern University
Other
Eligibility
18 Years to 29 Years · Male only
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Mar 4, 2013 · Synced Oct 24, 2026, 5:11 PM EDT
Completed Phase 2 Interventional

The Safety and Effectiveness of Ganciclovir in the Prevention of Cytomegalovirus (CMV) of the Eyes and Disease of the Stomach and Intestines in Patients With HIV

NCT00001034
View directory record Official record
Conditions
Cytomegalovirus Retinitis, HIV Infections, Gastrointestinal Diseases
Interventions
Ganciclovir
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
13 Years and older
Enrollment
850 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 1995
U.S. locations
17
States / cities
San Francisco, California • Denver, Colorado • Wilmington, Delaware + 12 more
Source: ClinicalTrials.gov public record
Updated Nov 4, 2021 · Synced Oct 24, 2026, 5:11 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Prevention and Risk: Treatment With a New Emphasis on Relationships

NCT03396367
View directory record Official record
Conditions
Adherence, Medication, Risk Reduction, Drug Use, Sex, Anal, HIV/AIDS
Interventions
PARTNER, Education Intervention
Behavioral
Lead sponsor
Hunter College of City University of New York
Other
Eligibility
18 Years to 29 Years · Male only
Enrollment
196 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 29, 2025 · Synced Oct 24, 2026, 5:11 PM EDT
Completed Not applicable Interventional

Toxoplasmic Encephalitis in Patients With AIDS. Treatment and Prevention of Relapse

NCT00002064
View directory record Official record
Conditions
Toxoplasmosis, Cerebral, HIV Infections
Interventions
Pyrimethamine, Clindamycin
Drug
Lead sponsor
Palo Alto Medical Foundation
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jun 24, 2005 · Synced Oct 24, 2026, 5:11 PM EDT
Completed No phase listed Observational

Optimizing CAB-LA as PrEP for Women Who Inject Drugs

NCT05799339
View directory record Official record
Conditions
HIV Infections, Opioid Use, Trauma, Psychological
Interventions
Not listed
Lead sponsor
Alexis Roth
Other
Eligibility
18 Years and older · Female only
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 29, 2025 · Synced Oct 24, 2026, 5:11 PM EDT
Completed Not applicable Interventional

Using Mobile Technology and Incentives With Men Who Have Sex With Men and Transgender Women for HIV Prevention

NCT03144336
View directory record Official record
Conditions
HIV Infections, HIV
Interventions
Information provision, Weekly quizzes, Rewards for testing HIV-negative
Behavioral
Lead sponsor
RAND
Other
Eligibility
18 Years and older
Enrollment
217 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 10, 2019 · Synced Oct 24, 2026, 5:11 PM EDT
Completed Not applicable Interventional

Providing PrEP, Hepatitis C Treatment, and MOUD Through Telemedicine at Greensboro SSP

NCT05108935
View directory record Official record
Conditions
Opioid Use, Opioid Use Disorder, Risk Reduction, Hiv, Hepatitis C
Interventions
Suboxone, Truvada, Mavyret
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
2
States / cities
Durham, North Carolina • Greensboro, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 27, 2023 · Synced Oct 24, 2026, 5:11 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Enhancing PrEP in Community Settings (EPIC)

NCT02371525
View directory record Official record
Conditions
HIV
Interventions
Prepmate
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 29 Years · Male only
Enrollment
121 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 26, 2017 · Synced Oct 24, 2026, 5:11 PM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers

Griffithsin-based Rectal Microbicide for PREvention of Viral ENTry (PREVENT)

NCT04032717
View directory record Official record
Conditions
HIV Prevention
Interventions
Q-Griffithsin (Q-GRFT) enema, Placebo enema
Drug · Other
Lead sponsor
Rhonda Brand
Other
Eligibility
18 Years to 45 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 6, 2023 · Synced Oct 24, 2026, 5:11 PM EDT