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ClinicalTrials.gov public records Last synced Oct 25, 2026, 12:00 AM EDT

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Showing 649–672 of 765 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Human Immunodeficiency Virus Prevention Clear all
Active, not recruiting Not applicable Interventional

Trauma Intervention to Optimize PrEP Among Women Who Inject Drugs

NCT05192434
View directory record Official record
Conditions
HIV Infections, Opioid Use, Trauma, Psychological
Interventions
Expressive Writing, Contingency Management
Behavioral
Lead sponsor
Drexel University
Other
Eligibility
18 Years and older · Female only
Enrollment
219 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 23, 2025 · Synced Oct 25, 2026, 12:00 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Improving Prevention Systems to Reduce Disparities for High Priority Populations

NCT03778164
View directory record Official record
Conditions
HIV Infections
Interventions
Fast Track Partner Services-Sexual Health Intervention
Other
Lead sponsor
Hunter College of City University of New York
Other
Eligibility
18 Years and older
Enrollment
451 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Oct 25, 2026, 12:00 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Study of Retrovir in the Prevention of HIV Infection in Health Care Workers Accidentally Exposed to the Virus

NCT00002287
View directory record Official record
Conditions
HIV Infections
Interventions
Zidovudine
Drug
Lead sponsor
Glaxo Wellcome
Industry
Eligibility
13 Years and older
Healthy volunteers
Accepts healthy volunteers
U.S. locations
1
States / cities
Research Triangle Park, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 24, 2005 · Synced Oct 25, 2026, 12:00 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Formative Study to Explore the Sensory Perceptions of Vaginal Product Users

NCT01334827
View directory record Official record
Conditions
Microbicide Delivery System Acceptability
Interventions
high volume gel, low volume gel, vaginal film
Other
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 15, 2025 · Synced Oct 25, 2026, 12:00 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Developing Rectal USPE Measures for Suppositories (Project DRUM-S)

NCT02744261
View directory record Official record
Conditions
Microbicide Delivery System Perceptibility and Acceptability
Interventions
Gel, Suppository 1, Suppository 2
Other
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Feb 10, 2026 · Synced Oct 25, 2026, 12:00 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Trial of Three Neonatal Antiretroviral Regimens for Prevention of Intrapartum HIV Transmission

NCT00099359
View directory record Official record
Conditions
Disease Transmission, Vertical, Vertical Human Immunodeficiency Virus Transmission, HIV Infections
Interventions
Zidovudine, Nevirapine (NVP), Epivir (3TC), Nelfinavir (NFV)
Drug
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
Up to 2 Days
Enrollment
1,735 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2011
U.S. locations
5
States / cities
Long Beach, California • Gainesville, Florida • Jacksonville, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 4, 2012 · Synced Oct 25, 2026, 12:00 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Safety and Pharmacokinetic Study of Oral MK-8527 QM in Participants at Low-Risk for HIV-1 Infection (MK-8527-007)

NCT06045507
View directory record Official record
Conditions
HIV, HIV Pre-exposure Prophylaxis
Interventions
MK-8527, Placebo to MK-8527
Drug
Lead sponsor
Merck Sharp & Dohme LLC
Industry
Eligibility
18 Years to 65 Years
Enrollment
352 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
10
States / cities
North Hollywood, California • San Francisco, California • Hallandale, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Oct 25, 2026, 12:00 AM EDT
Completed Not applicable Interventional

Pilot Mobile Medical Unit Study for I'm Fully Empowered4Her

NCT05644834
View directory record Official record
Conditions
HIV Prevention, Pre-exposure Prophylaxis, PrEP, Prevention, Women's Health, Mobile Health
Interventions
I'm Fully Empowered for Her (IFE4Her)
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 99 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 15, 2025 · Synced Oct 25, 2026, 12:00 AM EDT
Recruiting Not applicable Interventional

PrEP Readiness Interventions for Sustained Motivation (PRISM)

NCT06637436
View directory record Official record
Conditions
HIV, Methamphetamine Disorders
Interventions
Motivational Interviewing (MI), Contingency Management (CM)
Behavioral
Lead sponsor
Florida International University
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Oct 25, 2026, 12:00 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Increasing PrEP Among African Americans in Louisville KY

NCT03559595
View directory record Official record
Conditions
HIV/AIDS PREVENTION
Interventions
Project Prevent
Behavioral
Lead sponsor
University of Louisville
Other
Eligibility
18 Years to 29 Years
Enrollment
205 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 29, 2021 · Synced Oct 25, 2026, 12:00 AM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers

HIV Prevention Program for Patients Receiving Care at a Sexually Transmitted Diseases Clinic

NCT00183573
View directory record Official record
Conditions
HIV Infections, Sexually Transmitted Diseases
Interventions
Brief Motivational Intervention, Brief Informational Intervention, Intensive Informational Intervention, Intensive Info-Motivation-Behavioral Skills Intervention
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years and older
Enrollment
1,554 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Jun 7, 2013 · Synced Oct 25, 2026, 12:00 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Streamlining Telehealth for Expanded PrEP Utilization Through Community Partnerships

NCT07246057
View directory record Official record
Conditions
HIV
Interventions
STEP-UP, Philadelphia TelePrEP Program Direct-to-Consumer Model
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
16 Years and older
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 14, 2026 · Synced Oct 25, 2026, 12:00 AM EDT
Completed Not applicable Interventional Results available

HIV/STI Prevention for Drug-Involved Couples

NCT01285349
View directory record Official record
Conditions
Sexually Transmitted Infections
Interventions
Couple HIV/STI prevention intervention, Couple-based HIV/STI prevention, Individual HIV/STI prevention, Couple Wellness Promotion
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 40 Years
Enrollment
564 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 14, 2019 · Synced Oct 25, 2026, 12:00 AM EDT
Completed Not applicable Interventional

Enhancement of Connect to Protect® (C2P)

NCT01492816
View directory record Official record
Conditions
HIV Infection
Interventions
Community Mobilization
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
16 Years and older
Enrollment
927 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
9
States / cities
Los Angeles, California • Washington D.C., District of Columbia • Miami, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Feb 28, 2017 · Synced Oct 25, 2026, 12:00 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparative Effectiveness of Individual Versus Group-Level Interventions to Increase PrEP Uptake and Reduce HIV/STI Incidence

NCT06022809
View directory record Official record
Conditions
HIV, Other STIs
Interventions
Dada Kwa Dada (individual-level), DADA (group-level)
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
149 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
3
States / cities
Boston, Massachusetts • Roxbury, Massachusetts • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Feb 27, 2026 · Synced Oct 25, 2026, 12:00 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Peer-Driven Intervention to Increase PrEP Uptake Among Minority MSM

NCT05161663
View directory record Official record
Conditions
HIV Infections
Interventions
Peer-driven intervention
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years and older · Male only
Enrollment
98 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Oct 25, 2026, 12:00 AM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers Results available

Phase I Study to Evaluate a Human Monoclonal Antibody (MAb) 10E8VLS Administered Alone or Concurrently With MAb VRC07-523LS Via Subcutaneous Injection in Healthy Adults

NCT03565315
View directory record Official record
Conditions
Healthy Adult Immune Response
Interventions
VRC-HIVMAB095-00-AB (10E8VLS), VRC-HIVMAB075-00-AB (VRC07-523LS)
Biological
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
18 Years to 60 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 30, 2020 · Synced Oct 25, 2026, 12:00 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Network Intervention for Reducing Sexual Risk for HIV With African American Men Who Have Sex With Men (AA MSM)

NCT00691041
View directory record Official record
Conditions
HIV Infections
Interventions
Unity in Diversity
Behavioral
Lead sponsor
Centers for Disease Control and Prevention
Federal
Eligibility
18 Years and older · Male only
Enrollment
233 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 13, 2012 · Synced Oct 25, 2026, 12:00 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Safety, Tolerability, and Immunogenicity Study of Homologous Ad26 Mosaic Vector Vaccine Regimens or Heterologous Ad26 Mosaic and MVA Mosaic Vector Vaccine Regimens With Glycoprotein 140 (gp140) for Human Immunodeficiency Virus (HIV) Prevention

NCT02315703
View directory record Official record
Conditions
Healthy
Interventions
Ad26.Mos.HIV, MVA-Mosaic, gp140 DP Low-dose, gp140 DP High-dose, Placebo
Biological · Drug
Lead sponsor
Janssen Vaccines & Prevention B.V.
Industry
Eligibility
18 Years to 50 Years
Enrollment
393 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2022
U.S. locations
5
States / cities
Aurora, Colorado • Miami, Florida • Rockville, Maryland + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 4, 2025 · Synced Oct 25, 2026, 12:00 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Biktarvy for Non-Occupational Post-Exposure Prophylaxis (nPEP)

NCT03499483
View directory record Official record
Conditions
HIV Prevention
Interventions
bictegravir
Drug
Lead sponsor
Fenway Community Health
Other
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 7, 2022 · Synced Oct 25, 2026, 12:00 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Single Dose Truvada Study

NCT03719053
View directory record Official record
Conditions
Medication Adherence, HIV Prevention
Interventions
Tenofovir
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 16, 2020 · Synced Oct 25, 2026, 12:00 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Y2Prevent: Preventing Drug Use and HIV Through Empowerment, Social Support and Mentorship (Y2P)

NCT04504981
View directory record Official record
Conditions
HIV, Drug Use
Interventions
Y2Prevent
Behavioral
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
18 Years to 24 Years · Male only
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 18, 2023 · Synced Oct 25, 2026, 12:00 AM EDT
Completed Phase 1Phase 2 Interventional

HIV/STI Prevention for Adolescents With Substance Use Disorders in Treatment

NCT01383837
View directory record Official record
Conditions
HIV, Sexually Transmitted Diseases
Interventions
STYLEnS, Health Promotion
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
13 Years to 24 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 28, 2015 · Synced Oct 25, 2026, 12:00 AM EDT
Completed Phase 4 Interventional Results available

Evaluating the Response to Two Antiretroviral Medication Regimens in HIV-Infected Pregnant Women, Who Begin Antiretroviral Therapy Between 20 and 36 Weeks of Pregnancy, for the Prevention of Mother-to-Child Transmission

NCT01618305
View directory record Official record
Conditions
HIV Infections
Interventions
Lamivudine/zidovudine, Efavirenz, Raltegravir
Drug
Lead sponsor
Westat
Other
Eligibility
16 Years and older · Female only
Enrollment
408 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
4
States / cities
Fort Lauderdale, Florida • New Orleans, Louisiana • Memphis, Tennessee + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 30, 2020 · Synced Oct 25, 2026, 12:00 AM EDT