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Showing 1–24 of 143 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Hydration Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Dehydration, Rehydration, and Blood Viscosity

NCT02118883
View directory record Official record
Conditions
Dehydration
Interventions
Essentia Water, Bottled water
Other
Lead sponsor
Essentia Water, LLC
Industry
Eligibility
25 Years to 49 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Camden, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 15, 2014 · Synced Sep 5, 2026, 11:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of the Benefits of FloraGLO™ Lutein on Skin Health

NCT03769779
View directory record Official record
Conditions
Aging, Wrinkle, Skin Elasticity, Healthy, Hydration
Interventions
FloraGLO Lutein, Safflower Oil
Dietary Supplement
Lead sponsor
Kemin Foods LC
Industry
Eligibility
30 Years to 65 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Port Chester, New York
Source: ClinicalTrials.gov public record
Updated Feb 2, 2021 · Synced Sep 5, 2026, 11:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Efficacy of Different Oral Rehydration Solutions on the Hydration Status of Healthy Males

NCT05428774
View directory record Official record
Conditions
Fluid Retention, Beverage Hydration Index, Hydration Status
Interventions
Test product 1, Test product 2, Placebo
Other
Lead sponsor
Liquid I.V.
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 24, 2023 · Synced Sep 5, 2026, 11:32 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Oral Rehydration Solutions in Healthy Adult Athletes

NCT05569044
View directory record Official record
Conditions
Hydration
Interventions
Control Group, Oral Rehydration Solution, Water
Other
Lead sponsor
Abbott Nutrition
Industry
Eligibility
18 Years to 30 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Kent, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 5, 2026, 11:32 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Recombinant Hyaluronidase in Out-of-Hospital Setting: The EASI Access Trial

NCT00386386
View directory record Official record
Conditions
Mass Casualty Incident, Dehydration
Interventions
hypodermoclysis via recombinant hyaluronidase-facilitated subcutaneous infusion
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 12, 2008 · Synced Sep 5, 2026, 11:32 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Reference Values for Non-invasive Hydration Status Markers H10-14

NCT01387529
View directory record Official record
Conditions
Value Orientation
Interventions
Not listed
Lead sponsor
U.S. Army Medical Research and Development Command
Federal
Eligibility
18 Years and older
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 5, 2019 · Synced Sep 5, 2026, 11:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Clinical Trial to Evaluate Safety and Tolerability of a Novel Hydration Drink in Healthy Volunteers

NCT05428748
View directory record Official record
Conditions
Tolerance
Interventions
1 serving of test product, 2 servings of test product, 3 servings of test product, Placebo
Other
Lead sponsor
Liquid I.V.
Other
Eligibility
18 Years to 35 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 28, 2024 · Synced Sep 5, 2026, 11:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Beverage Hydration Index: Assessment of Four Rehydration Solutions

NCT06272435
View directory record Official record
Conditions
Hydration
Interventions
Multiplier, Sugar Free, Sugar Free with Amino Acids, Water
Dietary Supplement
Lead sponsor
University of Memphis
Other
Eligibility
18 Years to 45 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 15, 2024 · Synced Sep 5, 2026, 11:32 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Thirst for Knowledge

NCT07670767
View directory record Official record
Conditions
Geriatric Population
Interventions
Education with a regular hydration opportunity
Behavioral
Lead sponsor
Duquesne University
Other
Eligibility
60 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Cornwall, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Sep 5, 2026, 11:32 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Skin Hydration in Persons With Acne After Dietary Supplementation With Botanical Antioxidants

NCT04534140
View directory record Official record
Conditions
Acne Vulgaris, Acne
Interventions
HBKB Capsule, HBKB Supplement Vehicle
Dietary Supplement · Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 35 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 27, 2021 · Synced Sep 5, 2026, 11:32 AM EDT
Withdrawn Phase 2 Interventional

Dipyridamole/Magnesium To Improve Sickle Cell Hydration

NCT00276146
View directory record Official record
Conditions
Anemia, Sickle Cell
Interventions
oral dipyridamole, oral magnesium, or a combination of both
Drug
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
12 Years and older
Timeline
Started 2005
U.S. locations
3
States / cities
Detroit, Michigan • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 6, 2013 · Synced Sep 5, 2026, 11:32 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Preoperative Oral Hydration in the Ambulatory Arthroplasty Population

NCT05520593
View directory record Official record
Conditions
Same-day Discharge, Length of Stay
Interventions
Complex Carbohydrate Drink
Dietary Supplement
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 75 Years
Enrollment
312 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Sep 5, 2026, 11:32 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Caregiver Assessments of the Quality of Home Hospice Care

NCT00895024
View directory record Official record
Conditions
Advanced Cancer
Interventions
Phone Interview/Questionnaire
Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
74 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 28, 2020 · Synced Sep 5, 2026, 11:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Hydration Status When Consuming Alkaline Water Compared to Reverse Osmosis Purified Water.

NCT04460846
View directory record Official record
Conditions
Hydration
Interventions
Alkaline water, Reverse osmosis water
Dietary Supplement
Lead sponsor
Natural Immune Systems Inc
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Klamath Falls, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 26, 2022 · Synced Sep 5, 2026, 11:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

"Beverage Hydration Index" of Commercial Therapeutic Beverages

NCT03262597
View directory record Official record
Conditions
Healthy
Interventions
enterade, Pedialyte, Gatorade, Water
Other
Lead sponsor
Sonoma State University
Other
Eligibility
18 Years to 35 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Rohnert Park, California
Source: ClinicalTrials.gov public record
Updated Mar 6, 2018 · Synced Sep 5, 2026, 11:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Nuun Electrolyte Tablets on Hydration Status in Active Men and Women

NCT04422158
View directory record Official record
Conditions
Hydration
Interventions
Nuun electrolyte tablet, water
Dietary Supplement · Other
Lead sponsor
University of Memphis
Other
Eligibility
18 Years to 45 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 27, 2021 · Synced Sep 5, 2026, 11:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Healthy Hydration Pilot in Elementary Schools

NCT06132763
View directory record Official record
Conditions
Hydration, Dental Caries, Body Mass Index
Interventions
Hydration Intervention, Control - Assessments Only
Behavioral · Other
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
4 Years and older
Enrollment
563 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 30, 2025 · Synced Sep 5, 2026, 11:32 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Advancing Water Security: A Community Participatory School-Based Hydration Intervention

NCT06714929
View directory record Official record
Conditions
Dental Caries, Obesity Prevention
Interventions
Hydration
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
4 Years and older
Enrollment
7,200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Henrico, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Sep 5, 2026, 11:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Three-Group Study to Examine the Efficacy of the Air up® Drinking System at Improving Hydration and Associated Health Outcomes

NCT06290479
View directory record Official record
Conditions
Water Intake
Interventions
Air Up® Peach Pod, Air Up® Orangeade Pod
Dietary Supplement
Lead sponsor
air up GmbH
Industry
Eligibility
18 Years to 50 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Jul 18, 2024 · Synced Sep 5, 2026, 11:32 AM EDT
Completed Not applicable Interventional Results available

Senofilcon A Investigational Manufacturing Process

NCT01951703
View directory record Official record
Conditions
Visual Acuity, Comfort, Overall Vision
Interventions
senofilcon A
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
4
States / cities
Jacksonville, Florida • Bloomington, Illinois • Pittsburg, Kansas + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 18, 2018 · Synced Sep 5, 2026, 11:32 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Hydrate Heroes for Improving Brain Function & Mood

NCT07241260
View directory record Official record
Conditions
Hydration Status
Interventions
Hydrate Heroes (6 packets), Hydrate Heroes (3 packets)
Dietary Supplement
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Sep 5, 2026, 11:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Water With Anti-Inflammatory Capabilities on the Inflammatory Response to Heavy Resistance Exercise

NCT07456683
View directory record Official record
Conditions
Systemic Inflammation, Hydration, Resting Metabolism
Interventions
We made a water with berry essence volatiles (cranberry, blackberry, and blueberry). This was consumed for 6 weeks.
Other
Lead sponsor
University of Arkansas, Fayetteville
Other
Eligibility
18 Years to 39 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Fayetteville, Arkansas
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Sep 5, 2026, 11:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of AMP Human Sodium Bicarbonate Lotion on Hydration

NCT04598386
View directory record Official record
Conditions
Fluid Retention, Fluid Loss, Sodium Retention, Cognitive Change, Heat Exposure, Hyperhydration, Electrolyte and Fluid Balance Conditions
Interventions
PR Lotion - AMP Human Performance, Placebo Lotion
Other
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Storrs, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 13, 2021 · Synced Sep 5, 2026, 11:32 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Interaction of Caffeine and Hydration on Voice

NCT01435837
View directory record Official record
Conditions
Voice Disorders
Interventions
C2 (200mg of caffeine; 1/2 L of water), C3(200mg of caffeine; 1 L of water), C1 (200mg of caffeine, no water), Placebo (no caffeine, no water).
Drug
Lead sponsor
Southern Illinois University Carbondale
Other
Eligibility
18 Years to 35 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
Carbondale, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 10, 2013 · Synced Sep 5, 2026, 11:32 AM EDT